LOCUS       NM_017179               2388 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus UNC homeobox (Uncx), mRNA.
ACCESSION   NM_017179 XM_001065224
VERSION     NM_017179.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2388)
  AUTHORS   Sammeta,N., Hardin,D.L. and McClintock,T.S.
  TITLE     Uncx regulates proliferation of neural progenitor cells and
            neuronal survival in the olfactory epithelium
  JOURNAL   Mol Cell Neurosci 45 (4), 398-407 (2010)
   PUBMED   20692344
REFERENCE   2  (bases 1 to 2388)
  AUTHORS   Leitges,M., Neidhardt,L., Haenig,B., Herrmann,B.G. and Kispert,A.
  TITLE     The paired homeobox gene Uncx4.1 specifies pedicles, transverse
            processes and proximal ribs of the vertebral column
  JOURNAL   Development 127 (11), 2259-2267 (2000)
   PUBMED   10804169
REFERENCE   3  (bases 1 to 2388)
  AUTHORS   Mansouri,A., Voss,A.K., Thomas,T., Yokota,Y. and Gruss,P.
  TITLE     Uncx4.1 is required for the formation of the pedicles and proximal
            ribs and acts upstream of Pax9
  JOURNAL   Development 127 (11), 2251-2258 (2000)
   PUBMED   10804168
REFERENCE   4  (bases 1 to 2388)
  AUTHORS   Saito,T., Lo,L., Anderson,D.J. and Mikoshiba,K.
  TITLE     Identification of novel paired homeodomain protein related to C.
            elegans unc-4 as a potential downstream target of MASH1
  JOURNAL   Dev Biol 180 (1), 143-155 (1996)
   PUBMED   8948581
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Nov 26, 2020 this sequence version replaced NM_017179.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: D87748.1, SRR26643298.79805.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-785               JAXUCZ010000012.1  20210341-20211125   c
            786-961             JAXUCZ010000012.1  20209989-20210164   c
            962-2388            JAXUCZ010000012.1  20206604-20208030   c
FEATURES             Location/Qualifiers
     source          1..2388
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q11"
     gene            1..2388
                     /gene="Uncx"
                     /gene_synonym="Chx4; PHD1; Uncx4.1"
                     /note="UNC homeobox"
                     /db_xref="GeneID:29375"
                     /db_xref="RGD:69361"
     exon            1..785
                     /gene="Uncx"
                     /gene_synonym="Chx4; PHD1; Uncx4.1"
                     /inference="alignment:Splign:2.1.0"
     CDS             500..2092
                     /gene="Uncx"
                     /gene_synonym="Chx4; PHD1; Uncx4.1"
                     /note="homeobox protein Uncx4.1; paired-type homeodomain
                     transcription factor 1; Unc4.1 homeobox"
                     /codon_start=1
                     /product="homeobox protein unc-4 homolog"
                     /protein_id="NP_058875.2"
                     /db_xref="GeneID:29375"
                     /db_xref="RGD:69361"
                     /translation="MMDGRLLEHPHAQFGGSLGGVVGFPYPLGHHHVYELAGHQLQSA
                     AAAAAAASVPFSIDGLLSGSCAAAAASVVNPTPLLPAACGVAGESQPFKLADSGDPDK
                     ESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNR
                     RAKWRKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKS
                     QSRHLHSPGGLSLHSAPSSDSDSGGGGLSPEPPEPPPPTASAKGPGAHGSGIAGSAPV
                     PPGEPPAPGTCDPAFYPSQRSGAGSQPRLGRPADKDTVPCGPGAASTAGLPKASPFSV
                     ESLLSDSPPRRKATPANTAATAGLDFTPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQ
                     AALKGGAGPELVPKDAPPAPPAPPAPPAQASFGAFPGPVGAADPAFARRSPEVVASPG
                     PPAPASFRDLAAAAAESGAGDCADAGTVCPAAPPPPPLETSPGPGPRAPSPPGEPATC
                     GAAEPGAATGSSPPEGEEVDMD"
     exon            786..961
                     /gene="Uncx"
                     /gene_synonym="Chx4; PHD1; Uncx4.1"
                     /inference="alignment:Splign:2.1.0"
     exon            962..2388
                     /gene="Uncx"
                     /gene_synonym="Chx4; PHD1; Uncx4.1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atttgccgct caatgtctct ctgtaattgg agcaacatca ctttaaaggt tcagagagta
       61 cagcatttct ggtgaaaaat ccccacaaca cgccggcgaa tgttttaaag ggaaatctat
      121 tagaaggagg caaggggcgg gagcggcggg gggcaggagt ggggggctcg ccagggcccc
      181 cggccggccg agcgcggcgg cgcccctccc tccccacccc gtcttgttgt gacagctcct
      241 gatactgttt atggaggtgc gtgtcaggta taattagcaa tcgatatgga aaacgtttcc
      301 ttgcacccag cacgcctctg acgtcagagc cgattagcgc ttcttattgg tcccaaattc
      361 cccgggccgc ggctaattat cgagagcttg atgttgataa agtaaagcgg cggagcgcgg
      421 gccgaagcat gtgtagggct ccgggcccct gtccccgccg ccgtccgcgc ccccgcgccc
      481 caccagcccc gcgcgcgaga tgatggacgg tcgcctcctg gagcacccgc atgcccagtt
      541 cgggggctcg ctgggcggcg tggtgggctt cccctacccg ctgggccacc accacgtgta
      601 cgagctggcc ggtcaccagc tgcagtcggc cgccgccgcc gccgccgcgg cctcggtgcc
      661 cttctccatc gacggcctgc tcagcggctc gtgcgctgca gcagccgcct cggtggtcaa
      721 ccccacgccg ctgctgccgg ccgcctgcgg ggtggcgggc gaaagccagc ccttcaagct
      781 tgcagactcg ggggatccag acaaggagag ccccggctgc aaacggagac gcacccgcac
      841 taacttcacc ggctggcagc tggaggagct ggagaaggca ttcaatgaga gccactaccc
      901 ggacgtgttc atgcgcgagg cgctggcgct gcgcctggac ctggtcgagt cccgagttca
      961 ggtctggttc caaaatcgcc gggccaagtg gagaaagaag gagaacacca agaagggccc
     1021 gggccggcca gcccacaact cgcacccgac cacgtgcagc ggggagccca tggacccgga
     1081 ggagatcgct cgcaaggaac tggagaagat ggagaagaag aaacgcaaac acgagaagaa
     1141 actgctcaag agtcagagcc gccacctgca ctcgcccggt ggcctgtccc tgcacagcgc
     1201 gcctagctca gacagcgaca gcggtggcgg aggcctgtct ccagagccac ccgagcctcc
     1261 accgccgacc gcctcggcca agggccctgg agcgcacggc tctggcatcg cgggctccgc
     1321 tccggtacct cctggcgagc cacccgcgcc tggcacctgc gaccccgcct tctacccgag
     1381 ccaaagaagc ggcgccggct cgcagccgcg gctaggccgc ccggcggaca aggacacggt
     1441 cccttgcggg cccggagcgg cgtcgactgc aggcctgcct aaggctagcc cgttcagcgt
     1501 ggagagcctg ctgtccgact cgccaccgcg ccgcaaagcc accccagcca acactgcggc
     1561 cacagcgggg ttggacttca cgccggggct gccgtgcgca cctcggaccc tgattggcaa
     1621 gggccacttc ttgctctacc ccatcacgca gcccctcggc ttcctggtgc cacaggcagc
     1681 gctcaaggga ggagcaggcc ctgagttggt gcccaaggac gcgccccccg cgccgcccgc
     1741 gccgcccgca ccgcccgcgc aggccagctt cggggccttc cccggacctg ttggcgctgc
     1801 ggacccggct ttcgcccgtc gcagccctga ggttgttgcc tcccctgggc caccggctcc
     1861 cgcttctttc cgggacctag cagcggcggc agcggagagc ggtgccgggg actgcgcgga
     1921 cgcggggacc gtctgccccg cggccccgcc gcccccgccc ctcgaaacgt cgcccggtcc
     1981 gggccccaga gcccccagtc cacccggaga gccagccact tgcggcgccg ctgagccggg
     2041 cgctgctacg ggatccagcc cgcccgaggg cgaggaggtg gacatggact gagctgggga
     2101 ccgcggccgg aagaggcgct tagccagccg agcccgctcg ctcagcccca gactcccaac
     2161 gaatcaggtg atcggctctt agagacattg cttttccctc ctgctttttt tcccttcctt
     2221 ttattattat ttttaaaggc aaacgaaaac gctgtgtcga tggggaccaa ggcagcagct
     2281 gcaggtcctg gggtgaggtc ccctccttag gagggatcaa aagaccccgt atcccctaac
     2341 ccacaaaaac cccacaacga gaatcctcag ccttgtaaaa tgcaaaaa
//
