LOCUS       NM_001415084            9352 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus unc-5 netrin receptor C (Unc5c), transcript
            variant 1, mRNA.
ACCESSION   NM_001415084 XM_006233402
VERSION     NM_001415084.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 9352)
  AUTHORS   Shao,Q., Yang,T., Huang,H., Alarmanazi,F. and Liu,G.
  TITLE     Uncoupling of UNC5C with Polymerized TUBB3 in Microtubules Mediates
            Netrin-1 Repulsion
  JOURNAL   J Neurosci 37 (23), 5620-5633 (2017)
   PUBMED   28483977
REFERENCE   2  (bases 1 to 9352)
  AUTHORS   Hashimoto,Y., Toyama,Y., Kusakari,S., Nawa,M. and Matsuoka,M.
  TITLE     An Alzheimer Disease-linked Rare Mutation Potentiates Netrin
            Receptor Uncoordinated-5C-induced Signaling That Merges with
            Amyloid beta Precursor Protein Signaling
  JOURNAL   J Biol Chem 291 (23), 12282-12293 (2016)
   PUBMED   27068745
REFERENCE   3  (bases 1 to 9352)
  AUTHORS   Wetzel-Smith,M.K., Hunkapiller,J., Bhangale,T.R., Srinivasan,K.,
            Maloney,J.A., Atwal,J.K., Sa,S.M., Yaylaoglu,M.B., Foreman,O.,
            Ortmann,W., Rathore,N., Hansen,D.V., Tessier-Lavigne,M., Mayeux,R.,
            Pericak-Vance,M., Haines,J., Farrer,L.A., Schellenberg,G.D.,
            Goate,A., Behrens,T.W., Cruchaga,C., Watts,R.J. and Graham,R.R.
  CONSRTM   Alzheimer's Disease Genetics Consortium
  TITLE     A rare mutation in UNC5C predisposes to late-onset Alzheimer's
            disease and increases neuronal cell death
  JOURNAL   Nat Med 20 (12), 1452-1457 (2014)
   PUBMED   25419706
  REMARK    GeneRIF: T835M (rs137875858) in UNC5C increased hippocampal
            neuronal cell death and susceptibility to neurotoxic stimuli.
REFERENCE   4  (bases 1 to 9352)
  AUTHORS   Srinivasan,K., Leone,D.P., Bateson,R.K., Dobreva,G., Kohwi,Y.,
            Kohwi-Shigematsu,T., Grosschedl,R. and McConnell,S.K.
  TITLE     A network of genetic repression and derepression specifies
            projection fates in the developing neocortex
  JOURNAL   Proc Natl Acad Sci U S A 109 (47), 19071-19078 (2012)
   PUBMED   23144223
REFERENCE   5  (bases 1 to 9352)
  AUTHORS   Purohit,A.A., Li,W., Qu,C., Dwyer,T., Shao,Q., Guan,K.L. and Liu,G.
  TITLE     Down syndrome cell adhesion molecule (DSCAM) associates with
            uncoordinated-5C (UNC5C) in netrin-1-mediated growth cone collapse
  JOURNAL   J Biol Chem 287 (32), 27126-27138 (2012)
   PUBMED   22685302
REFERENCE   6  (bases 1 to 9352)
  AUTHORS   Goldowitz,D., Hamre,K.M., Przyborski,S.A. and Ackerman,S.L.
  TITLE     Granule cells and cerebellar boundaries: analysis of Unc5h3 mutant
            chimeras
  JOURNAL   J Neurosci 20 (11), 4129-4137 (2000)
   PUBMED   10818148
REFERENCE   7  (bases 1 to 9352)
  AUTHORS   Eisenman,L.M. and Brothers,R.
  TITLE     Rostral cerebellar malformation (rcm/rcm): a murine mutant to study
            regionalization of the cerebellum
  JOURNAL   J Comp Neurol 394 (1), 106-117 (1998)
   PUBMED   9550145
REFERENCE   8  (bases 1 to 9352)
  AUTHORS   Przyborski,S.A., Knowles,B.B. and Ackerman,S.L.
  TITLE     Embryonic phenotype of Unc5h3 mutant mice suggests chemorepulsion
            during the formation of the rostral cerebellar boundary
  JOURNAL   Development 125 (1), 41-50 (1998)
   PUBMED   9389662
REFERENCE   9  (bases 1 to 9352)
  AUTHORS   Ackerman,S.L., Kozak,L.P., Przyborski,S.A., Rund,L.A., Boyer,B.B.
            and Knowles,B.B.
  TITLE     The mouse rostral cerebellar malformation gene encodes an
            UNC-5-like protein
  JOURNAL   Nature 386 (6627), 838-842 (1997)
   PUBMED   9126743
REFERENCE   10 (bases 1 to 9352)
  AUTHORS   Lane,P.W., Bronson,R.T. and Spencer,C.A.
  TITLE     Rostral cerebellar malformation, (rcm): a new recessive mutation on
            chromosome 3 of the mouse
  JOURNAL   J Hered 83 (4), 315-318 (1992)
   PUBMED   1401878
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Dec 21, 2022 this sequence version replaced XM_006233402.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360190.2771728.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-239               JAXUCZ010000002.1  232854352-232854590
            240-461             JAXUCZ010000002.1  233057436-233057657
            462-605             JAXUCZ010000002.1  233091055-233091198
            606-709             JAXUCZ010000002.1  233110611-233110714
            710-890             JAXUCZ010000002.1  233136836-233137016
            891-1058            JAXUCZ010000002.1  233141298-233141465
            1059-1223           JAXUCZ010000002.1  233144102-233144266
            1224-1280           JAXUCZ010000002.1  233160281-233160337
            1281-1472           JAXUCZ010000002.1  233162255-233162446
            1473-1817           JAXUCZ010000002.1  233163095-233163439
            1818-1905           JAXUCZ010000002.1  233164982-233165069
            1906-2074           JAXUCZ010000002.1  233174705-233174873
            2075-2308           JAXUCZ010000002.1  233177078-233177311
            2309-2458           JAXUCZ010000002.1  233190582-233190731
            2459-2623           JAXUCZ010000002.1  233191818-233191982
            2624-2802           JAXUCZ010000002.1  233200998-233201176
            2803-9352           JAXUCZ010000002.1  233201933-233208482
FEATURES             Location/Qualifiers
     source          1..9352
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q44"
     gene            1..9352
                     /gene="Unc5c"
                     /note="unc-5 netrin receptor C"
                     /db_xref="GeneID:362049"
                     /db_xref="RGD:735109"
     exon            1..239
                     /gene="Unc5c"
                     /inference="alignment:Splign:2.1.0"
     CDS             116..2968
                     /gene="Unc5c"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; netrin receptor UNC5C; unc-5 homolog 3; protein
                     unc-5 homolog C; protein unc-5 homolog 3"
                     /codon_start=1
                     /product="netrin receptor UNC5C isoform 1 precursor"
                     /protein_id="NP_001402013.1"
                     /db_xref="GeneID:362049"
                     /db_xref="RGD:735109"
                     /translation="MRKGLRATAARCGLGLGYLLQMLVLPALALLSASGTGSAAQDDD
                     FFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQ
                     KDHVVDERVDETSGLIVREVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYV
                     RIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPMAEVEWLKNEDIIDPVEDRNFYI
                     TIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWAEWSVCNSRC
                     GRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTLCPVDGRWTSWSKWSTCGTECTH
                     WRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLCMQGFIYPISTEHRTQSEYGFSSAPD
                     SDDVALYVGIVIAVTVCLAITVVVALFVYRKNHRDFESDIIDSSALNGGFQPVNIKAA
                     RQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNSSGAVT
                     PQDDLAEFSSKLSPQMTQSLLENEALNLKNQSLARQTDPSCTAFGTFNSLGGHLIIPN
                     SGVSLLIPAGAIPQGRVYEMYVTVHRKENMRPPMEDSQTLLTPVVSCGPPGALLTRPV
                     ILTLHHCADPNTEDWKIQLKNQAVQGQWEDVVVVGEENFTTPCYIQLDAEACHILTEN
                     LSTYALVGQSTTKAAAKRLKLAIFGPLCCSSLEYSIRVYCLDDTQDALKEVLQLERQM
                     GGQLLEEPKALHFKGSIHNLRLSIHDITHSLWKSKLLAKYQEIPFYHIWSGSQRNLHC
                     TFTLERLSLNTVELVCKLCVRQVEGEGQIFQLNCTVSEEPTGIDLPLLDPASTITTVT
                     GPSAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDL
                     WEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGQY"
     exon            240..461
                     /gene="Unc5c"
                     /inference="alignment:Splign:2.1.0"
     exon            462..605
                     /gene="Unc5c"
                     /inference="alignment:Splign:2.1.0"
     exon            606..709
                     /gene="Unc5c"
                     /inference="alignment:Splign:2.1.0"
     exon            710..890
                     /gene="Unc5c"
                     /inference="alignment:Splign:2.1.0"
     exon            891..1058
                     /gene="Unc5c"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1223
                     /gene="Unc5c"
                     /inference="alignment:Splign:2.1.0"
     exon            1224..1280
                     /gene="Unc5c"
                     /inference="alignment:Splign:2.1.0"
     exon            1281..1472
                     /gene="Unc5c"
                     /inference="alignment:Splign:2.1.0"
     exon            1473..1817
                     /gene="Unc5c"
                     /inference="alignment:Splign:2.1.0"
     exon            1818..1905
                     /gene="Unc5c"
                     /inference="alignment:Splign:2.1.0"
     exon            1906..2074
                     /gene="Unc5c"
                     /inference="alignment:Splign:2.1.0"
     exon            2075..2308
                     /gene="Unc5c"
                     /inference="alignment:Splign:2.1.0"
     exon            2309..2458
                     /gene="Unc5c"
                     /inference="alignment:Splign:2.1.0"
     exon            2459..2623
                     /gene="Unc5c"
                     /inference="alignment:Splign:2.1.0"
     exon            2624..2802
                     /gene="Unc5c"
                     /inference="alignment:Splign:2.1.0"
     exon            2803..9352
                     /gene="Unc5c"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttatttctc aggactgcct ggcggtggcc ggatctagcc tcctgcccgg cggggctttc
       61 tgctgtttgc gcgtctcctg gtggcgttac ccttccccgc acacctctgc cgacgatgag
      121 gaaaggtctg agggcgacag cggcccgctg cggactggga ctaggatact tgctgcagat
      181 gcttgtgtta cctgccctgg ccctgctcag cgccagtggc accggctcgg ccgctcaaga
      241 tgatgacttt ttccatgaac tcccagaaac ctttccatca gacccacctg agccattacc
      301 acactttctc attgagcccg aggaagctta cattgtgaag aacaagcctg tgaacctgta
      361 ttgtaaagcc agccctgcca cccagatcta cttcaagtgc aacagcgaat gggttcatca
      421 gaaggaccac gtagtagacg agagggtaga tgaaacctcc ggtctcattg tgagagaagt
      481 gagcattgag atttcacgcc agcaggtgga ggaactgttc gggcctgaag attactggtg
      541 ccagtgtgtg gcctggagct cagcgggcac tacgaagagt cggaaggcat acgtgcgcat
      601 tgcgtatctg cggaagacat ttgagcagga acccttggga aaagaagtgt ccttggagca
      661 ggaagtgtta ctccagtgcc ggccacctga agggatccca atggctgagg tggagtggct
      721 aaagaatgaa gacataattg atcctgtcga agatcggaat ttttatatca ctatcgatca
      781 caacctgatc atcaagcagg cacgactctc agatacagcg aattatacct gtgttgccaa
      841 aaacattgtt gccaagagga aaagcaccac agccaccgtc atcgtgtatg ttaatggtgg
      901 ctggtccacc tgggcagaat ggtctgtgtg taacagccgc tgtgggcgag gatatcagaa
      961 acgcacaaga acctgcacca acccagcccc cctcaatggt ggggccttct gcgaggggca
     1021 gagtgtacag aaaatagcat gcaccacgtt atgcccagtg gatggcaggt ggacttcgtg
     1081 gagcaaatgg tcaacttgtg ggactgagtg cacccactgg cggaggaggg agtgtacagc
     1141 accagccccc aagaacgggg gtaaggactg tgatggcctg gtcctccaat ccaagaactg
     1201 caccgatggg ctgtgcatgc agggattcat ttaccccatt tcaactgagc acagaaccca
     1261 gagtgaatat ggattttctt ctgctcctga ctcagatgac gttgctctct acgttgggat
     1321 tgtgatcgct gtaaccgttt gtctggcaat cactgttgtg gtggccctgt tcgtgtatcg
     1381 caagaaccac cgtgactttg agtctgatat cattgactcc tcagcactca atggcggctt
     1441 tcagcctgtg aacatcaagg ctgccagaca agatctcctg gcagtacccc cggatctcac
     1501 ctcagctgca gccatgtaca ggggacccgt ctatgctctg catgatgtct cagacaaaat
     1561 cccaatgacc aattctccaa ttctagaccc actgcccaat ttgaaaatca aagtgtacaa
     1621 cagctcaggt gctgtcactc ctcaggacga ccttgctgag ttctcatcca agctgtcacc
     1681 ccagatgacc caatccttgc tagagaatga ggccctgaac ctgaagaacc agagtctcgc
     1741 aagacagact gacccatcct gcacagcgtt tggcaccttc aactccctgg gcggtcacct
     1801 catcatccct aattcaggag taagcttgct gattcccgct ggggccattc ctcaggggag
     1861 agtctatgaa atgtatgtga ctgtacacag gaaagaaaat atgaggcccc ccatggaaga
     1921 ctctcagacc ctgctgaccc ctgtggtgag ctgtgggcct cctggagctc tgttgacccg
     1981 tcctgtcatc ctcactctgc atcactgtgc agaccctaac accgaggact ggaagatcca
     2041 gctcaaaaac caggcagtgc agggacagtg ggaggatgtt gtggttgttg gagaggaaaa
     2101 cttcacaacc ccctgttaca ttcagctgga tgcagaggct tgccatattc tcacggagaa
     2161 cctcagtacc tatgccctgg ttgggcagtc caccaccaaa gcagctgcca agcgtctgaa
     2221 gctggccatc tttgggcccc tctgctgctc ttccctggag tatagcatca gagtctactg
     2281 cctggatgac acacaggatg ccctgaagga agttctacaa ctggaaaggc aaatgggagg
     2341 acagctccta gaagaaccca aggctcttca ttttaaaggc agcatccaca acctgcgcct
     2401 ctcaattcat gacatcaccc attccctctg gaagagcaaa ttgctggcta agtatcagga
     2461 aattccattt taccacatct ggagtggctc tcaaagaaac ctccactgta ccttcactct
     2521 ggaaagactc agcctaaaca cagtagagct ggtttgcaaa ctctgtgtgc ggcaggttga
     2581 aggagaaggg cagatcttcc agctcaactg tactgtgtca gaggaaccta ctggtatcga
     2641 tttgcctctc ctggaccctg ctagcaccat taccactgtc actggaccaa gtgctttcag
     2701 catccctctt cctatccggc agaagctatg tagcagcctg gatgcccccc aaacaagagg
     2761 ccatgactgg aggatgctgg cccacaaact taacctggac aggtacttga attactttgc
     2821 caccaaatcg agcccgactg gcgtaatcct ggatctctgg gaagcacaga acttccccga
     2881 tggaaacctg agcatgctgg cagccgtcct ggaagaaatg ggaagacacg aaaccgtagt
     2941 gtccttggca gcagaaggtc agtattgacc acaccggaac cgacactgaa ggacaaaatt
     3001 acacagggag tctgtgttca ggggaaccac atctgaggag gaaatccaga taggaccaag
     3061 gcgctttaca ggcaagatgg caacaggaaa cgtgggggac agatacaacc accaaggtac
     3121 acgcccactt cattcggaca gtaccaccac gggagctaag gaaaacaatg tgtaaatttg
     3181 taccttgaat ttaacaatca atctaatttt ctcttcattg ggctgtatgc tgtatggtac
     3241 aggatcttac agtttcctag gaaacgcttt atattgctat ccagatgtat ggataaactt
     3301 tcttaacaaa cccagtttct acaaatgttg tttacatcaa attggacagg gatgcagacg
     3361 ctgtccatgg ctcgttctat ttttgttcag atcatttgaa gttgaagctg tggacggttg
     3421 attgtgtcta tttcagatta gtaatttaca gagaaatcac agactttttg ctacaaattg
     3481 tgtacatcga gtgtctcaga taatcttccc atcagtgttc tgtttctgaa acttgttgga
     3541 ccagtattgc cattggtatc agggaagtgg agaatctcaa tgtaaaggag aaattgctaa
     3601 aattccttac gtgatggggg ggcccggtcg gtgtcctttg ggaacaacct ttgctgtggt
     3661 attacaggga aggtagcgac tcaggtccct ccacacaaac atttctgtgt cacgtgtgtg
     3721 tttgtaataa gcaatttcaa gtgttttttg aaaaagtatt atcattatta ctgatgatta
     3781 tcacaactat tctagtgaaa agatttttct tttgttttag ttagcaatac tgttagtgtt
     3841 tggtgttgac tgggcctgcc tccctttctt gcctaaagag gtgggatatg gtcaccagtt
     3901 tagttcaata gcttttgctt ccttgacctt tgacctacta ttctgtggtg gaaaagacaa
     3961 aaatgctcag tggctatgtc tgctctttca gcttgcttgg tcagagcctt tctcctcttg
     4021 ctcttatcat gaggagagtt ctctatgtaa agttcattta cttttgtggc tgtctttctg
     4081 ggaggcagtg ggactgtggg taacagtgaa ctaggaatca ggaaaagtta tccttgtgaa
     4141 gttggtcact gtctggctgt gtgactttgg ggagaaccct gagagtcact ggagctcatt
     4201 gtccttctat gtaaacaatg gagaccagat catctcaagg ttccagcatg ctgatatccc
     4261 attgggatat catcagcctt ttacatcttg caggcaggat tgacttgaaa gggggatgac
     4321 ttcaacatgc atttatttgt ttgcctttgt ctttgtatca tcgttgcatg atgttcaccg
     4381 agagagggca tccttttctt attgtcttga cctctagtgg ggccctaccc tccagccgac
     4441 caactaattg taaattctac tttacccatt tattgatctc tagatctcaa gaccatttct
     4501 actaaaagcc catgcagctg aaggactcgg taccattttt cttcctttat taatctttgc
     4561 tttaataata tgcagttgta tttacagcct tttattatcc ctttaaccct ataaaatgtt
     4621 gtacatacca caagttctcc ttgggaccat cttggttttg gtttgtttgt ttctttgggg
     4681 ctttttgttg ttgttgtttt gttttgtttt gtttttgata taggaactcc attcagcaga
     4741 tggtgaatga aaacttagca accccatagt tacagttgca gttaaatagg aagcacccgt
     4801 gtccttaagt cagagacttc aaaatgtggc tgtggtatac tttggggctg gaagtatcca
     4861 ggttgctgag tggattccag ttgggaatcg ttttgcctaa tgctccctcc aattctttta
     4921 cttcctgata ctctccgtcc cttccactgt agtcattaag gaaccatgga aacagttgcg
     4981 gagacttcct tcacggtgtt tttcttctct ttcagagatg tatcctccaa tctctctaac
     5041 ctcattcata tgtaagactc ctggttccac tggtggtggg aggcgaattc tatactccta
     5101 tgaaagccca gtggctgatg tctagaacta tgagtttgtt tgaattttta agagtttgat
     5161 agatattctt aaaaagcaag aggaagaaag acagtcattg ctgcctcttg aaacaaaggt
     5221 gtggatgttc ctcttcgcta cttggatttt ggaaccatcc aagtaatcca aactgagaga
     5281 tcttgactgg atattctgtg taacttcaat gctttgtgct aagtcaagag agacaaacat
     5341 gttgctgttc tggataattt atcctaaaaa cccgttaagt aaccatcata gacatactga
     5401 atataaccaa agcaacatta ttgagtcttt tcagagtcct catgttcaag catctagaga
     5461 tactggcttt tctattcaga ctctcacaac aggaaaagga aacattactg atatcttatg
     5521 aaggaatcat ttgtcataaa actacttttc tgtcatgcga atgacagttt ccaaactaga
     5581 acataccaaa catcaaataa tttcctctta agcagtctgc tctttctcct taggaagaaa
     5641 ataatagttg ttagattgct gctttccaac acaccaggtt cacctggcat agttcatttt
     5701 agagggagct tcatcatcac ctctgtggca tgtctgactt ctacagagct tctgaggaaa
     5761 gccttgcttg ctctgggtgg gttaaaaaaa actaattatt tgtgcatggt gccatctagt
     5821 ggcctgccac atagttactc aattttacat acagcttaca aaaagttgac agttaagtac
     5881 ctgtggagtt tgacataaca tttgtgacag acgtggggga atttacccac gtgcgtaact
     5941 ctcttattct catattcttc agttaaatca tctattccac aattttctgg gtatattacc
     6001 tcatcaaatt actcattcac accttaagtt attttctagt aatagacata tatggaatct
     6061 atattaaaaa gtctctgaaa gttgtcattc tttatttatg aatgccattg ggttttgcat
     6121 attttaaatc ttttaattcc aaaacattaa cttttagaag cataagctct agtcacaaag
     6181 aagcccccct gtccaccatc tccacataca tatacaaacg catggcatcc cctttggggt
     6241 tttgttattt gatttactat tttgatatat attcttacta ggtattccag aacaccctca
     6301 aatccatcac cctattgccc ctgcctctct catgtggtgg gagtttaagt atgtaccata
     6361 gacctgcttc aacctgctct gcatctggaa atgagagtcc tgtgtctatg gatgtgggag
     6421 ttgtggctgt taatcaaggt gatactcttt caatgaagta gactttctga gatcaggaat
     6481 ctaacgctcc atgacctcat cttattgtta tgacattaat tcaaatgggc ttgagtacat
     6541 gagtagaagg gtgtgtcaag aaagtcacag cccaaacatc ttcaaagcac tcacattgtc
     6601 tctgctacac aagaacttca tcctgacctg agcaaattaa tctcttcggg gaaagaataa
     6661 tttgggagat gagaggtcca agatcaaagt atagcattag ctattttcac atatgctatg
     6721 agtctataga ttttaattat tccactatca aagagtagag acattcttga gggaaaagtt
     6781 gtcatagcta tatttaggat cctctaggaa acaggtatta aagacatttc ttctaaaagt
     6841 gtttgaaaag gaaaccttca gagggtggga tttagacagt tcatatctgg agcagggtag
     6901 atggttgcta catctctgtg tgtctccgat gaggacttgg cagctgtgat cctgcatcat
     6961 tcacacctcc atagccacag gacaaaggag agcttataag gttgatgtcc tgccccagaa
     7021 tccatacata tgcctacagt ctgtgctctg gagccaatca gtgtagaagg atgttgaaca
     7081 atatgagaga acaagtagaa aagattgact tgttgcgagt ctccaagatg aacatgaatt
     7141 tgagctgagt aattgctcca gaaaagagat ccattcagag atagatacta atgcaagtcc
     7201 aaggccaggg tggcaaagga gggactacag aaacacagtg gggggtggaa ttaggcttga
     7261 gatgcctttt ctgagaagct ttgtaaatca gaacaccatt gttcaaatca gtcatttgta
     7321 aagatgataa tggccaatga gcatcttatt ttatagatcc aaaagaaaaa tatttttatt
     7381 attattctca agataataaa actggttttg ccttctgagt gcctcgtggg accaactatc
     7441 ttattccttt agttttgtat tgtttttgta tttttaaagc atactgagct gacattgact
     7501 tataactctt acaactctct gtacaacaga gtactgtttc tctgccccaa gagatccgat
     7561 tgtaccacct ctgcaacagt tacctgagaa tttcctgatg taattgggac tatgaggaat
     7621 acatttatta tgttcatatg ggctaagtaa gccatatgaa gttatgtttc ccaaaatctg
     7681 acacttatgt aagctttgtt aaatgagtag agatggcctg catgtacctg ggtggagtat
     7741 ctcgtcaaac taacagtgtg gttgtgaatc ctttagtcct tttgaacaaa tggttgccct
     7801 tttttcctga aaacctattg caatggtctt cagaaagtcc agtgggcttg gctgcttcct
     7861 ttattgatct gtggtgggat attaacgggc ttattcaacc aaaggtattt tcagaggcct
     7921 atttcagtat ggctggggta tcctcaggac aaataagaca tactccataa acatgctagc
     7981 aggtaaagcc aatgaaatgt aagaggtgac ctgcaagtct tcagtataca caactatgaa
     8041 ggaatctatc ccaagaatta ccagaatcct aaattggaag ctcctgccat atatcaggac
     8101 cgtcatggcc aaccccacta gttgttaagc agaaaaccag ggactgtcct gagatacaat
     8161 cagctgtcca ccagccatgt tatttactac ggtacaccag ctttttatat atcatttggg
     8221 aacctgtgct agagcagaat tataaattgc aggctatcat actgtatgac ccattttaaa
     8281 taagcctaaa ctccatgtca tccttacatg ccaaaggcct aatgccatgg agcccgatga
     8341 cacccagcca tggtgactga actgtgggct ggttgtcctg atgggcagcc taagggacga
     8401 gctctctgcc tttgatcttc actcagcatg aagatgtggc aacatcaaag catcatgatg
     8461 agccctgtgc tatgttaaag caattttaag atggcgtacg aaacaaattc acagctagta
     8521 gaacatacct ttgccctttc tgtgttccta aagtcatcaa tggcacccat aactgcacat
     8581 atatggattc agacattttt ttctccagat tattggaaag aaagaagagc cagttaaaca
     8641 catgacttgc gttctttctt tcacttgttc ctagtcctac tatgggtatt gatgccctta
     8701 cctttcagac aatgtattta gccaagttgc agggaatatc attactctgt gtgtgtgtgt
     8761 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgttagatg tcacagtgtt gtgtgtatta
     8821 agcttaatgt tgagctgtaa ggaaccagtc atcttcctcc ttgttctaaa gaagaaaacc
     8881 catattcatc agagaacaat ccccagcttg ctgctaaaaa gaggctgggt caccctcctg
     8941 ctgtcttctt tggaccaggt caacttcaga agtatcaggt tgaaatttta agctctgtca
     9001 gttttttttt tcccttcttt tagcaaaaca acatgacctt ggcttcccag atatggaacc
     9061 cttccttcct ttgttacaga attctgtctt gctgtatctt ctatgcaatt ccttttctaa
     9121 tgacccctag tggctgagga gtgctctgca gcactccgct tgtcgccttg ctgtgcggtg
     9181 gaggtgaggg ataccagctt tgggtgtgcc tcttttctct ccctggttgc ctctcaccca
     9241 attttcctgc agtccccttg gtttgtaaat tgcctgcatt tactctgtca gccaacgtgt
     9301 acaaatgtaa gaaagaattt ttaaacaggt aataaattat atttataagc aa
//
