LOCUS       NM_001037647            3335 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus unc-45 myosin chaperone A (Unc45a), mRNA.
ACCESSION   NM_001037647 XM_218818
VERSION     NM_001037647.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3335)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3335)
  AUTHORS   Liu,L., Srikakulam,R. and Winkelmann,D.A.
  TITLE     Unc45 activates Hsp90-dependent folding of the myosin motor domain
  JOURNAL   J Biol Chem 283 (19), 13185-13193 (2008)
   PUBMED   18326487
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC107919.1.
            
            On Dec 9, 2005 this sequence version replaced XM_218818.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC107919.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3335
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q31"
     gene            1..3335
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /note="unc-45 myosin chaperone A"
                     /db_xref="GeneID:308759"
                     /db_xref="RGD:1305357"
     exon            1..175
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
     CDS             125..2959
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /note="SMAP-1; UNC-45A; smooth muscle cell-associated
                     protein 1; unc-45 homolog A"
                     /codon_start=1
                     /product="protein unc-45 homolog A"
                     /protein_id="NP_001032736.1"
                     /db_xref="GeneID:308759"
                     /db_xref="RGD:1305357"
                     /translation="MTVSGPGTPEPRPSDPGASSAEELRKEGNELFKCGDYEGALTAY
                     TQALSLGATPQDQAILHRNRAACHLKLEDYSKAESEASKAIEKDGGDVKALYRRSQAL
                     EKLGRLDQAVLDLKRCVSLEPKNKVFQESLRNIGGQIQEKVRYMSSTDAKVEQMFQIL
                     LDPKEKGTEKKQKASQNLVVLAREDAGAEKIFRSNGVQLLQRLLDTGETDLMLAALRT
                     LVGICSEHQSRTVATLSVLGTRRVVSILGVENQAVSLAACHLLQVMFDALKEGVKKGF
                     RGKEGAIIVDPARELKVLISNLLELLTEIGVSGQGRDNALTLLIKMVPRKSPKDPNNS
                     LTLWVIDQGLKKILEVGGSVPEAAGELTVTANSRMSASILLSKLFDDLKCDAERENFH
                     RLCENYIRSWFEGQGLAGKLRAIQTVSCLLQGPCDAGNRALELSGVMESVIALCASEQ
                     EEEQLVAVEALIHAAGKAKRASFITANGVALLKDLYKGSERDSIRIRALVGLCKLGSA
                     GGTDFSMKQFAEGSTLKLAKQCRKWLCNDQIDAGTRRWAVEGLAYLTFDADVKEEFVE
                     DEAALKALFQLSRSEERSVLFAVGSALVNCTNSYDYEEPDPKMVELAKYAKQHVPEQH
                     PKDKPSFVRARVKKLLAAGVVSAMTCMVKTESPVLTNSCRELLSRVFLALVEEVEDRG
                     TVVAQGGGKALLPLALEGTDVGQTKAAQALAKLTITSNPEMTFPGERIYEVVRPLVSL
                     LHLSCSGLQNFEALMALTNLAGISERLRQKILKEKAVPMIEGYMFEEHEMIRRAATEC
                     MCNLAMSKEVQDLFEAQGNDRLKLLVLYSGEDDELLRRAAAGGLAMLTSMRPSLCSRI
                     PQVTTHWLEILQALLLSPNPELQHRGTVVVLNMMESSKEIASTLMESEVLEILSVLAK
                     GEESPVTRAAAACLEKAVEYRLIQPNQDGE"
     exon            176..337
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
     exon            338..374
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
     exon            375..550
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
     exon            551..643
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
     exon            644..811
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
     exon            812..980
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1151
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
     exon            1152..1323
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
     exon            1324..1624
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
     exon            1625..1719
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
     exon            1720..1861
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
     exon            1862..2002
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
     exon            2003..2130
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
     exon            2131..2197
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
     exon            2198..2311
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
     exon            2312..2427
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
     exon            2428..2545
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
     exon            2546..2701
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
     exon            2702..3309
                     /gene="Unc45a"
                     /gene_synonym="RGD1305357"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgccttcttt ggcgtaaccc tgacgcattg ctggggcggg gcagtcaccg gcatcttccg
       61 gagcccaggg ctaccttagc tccagtgact gtgcctgcac cggctcttgg agctcagctt
      121 cgtgatgact gtgagtggtc cggggacccc cgagccccga ccttccgacc ccggggccag
      181 ctcagccgag gagctgcgga aggagggcaa cgagctgttc aaatgcgggg attacgaggg
      241 cgccttgacc gcctacaccc aggccctgag tcttggcgcg acaccccagg accaggctat
      301 tttgcaccga aaccgggctg cttgccacct caagctggaa gattacagca aagcagaatc
      361 agaggcatct aaagccattg aaaaggacgg tggggatgtc aaagcacttt atcgacgaag
      421 ccaagcccta gagaagctgg gccgcctgga ccaggctgtc cttgacctga agagatgtgt
      481 gagcctagaa cccaagaaca aagttttcca ggagtccctg aggaacattg ggggccagat
      541 tcaggagaag gtgcggtaca tgtcctccac agatgccaaa gtggaacaga tgtttcagat
      601 actgttggac cccaaagaga aaggcacaga gaagaagcag aaggcttctc agaaccttgt
      661 ggtactggcc cgagaggatg ctggagccga gaagatcttc cggagcaatg gggttcagct
      721 tttgcagcgc ctactggaca cgggagagac tgacctcatg ctggcagccc tgcgcacact
      781 ggtcggcatt tgctctgagc accagtctcg gacagtggcg accctgagtg tcctaggaac
      841 tcggagagtc gtctccatcc tgggtgtgga aaaccaggct gtgtcgctgg cagcctgcca
      901 cctgctgcag gttatgtttg atgccctcaa ggaaggcgtc aagaaaggct tccgaggcaa
      961 agaaggtgcc attatcgtgg atcctgcccg ggagctgaag gttctcatca gtaacctctt
     1021 ggagcttctg actgagatag gggtctctgg ccaaggccgg gacaatgccc tgaccctcct
     1081 cattaaaatg gtacctcgga agtcaccgaa agatcccaac aacagcctca cactctgggt
     1141 cattgatcaa ggtctgaaaa agattctgga ggtggggggc tctgtgccgg aggccgccgg
     1201 ggagctcacg gtgaccgcaa acagccgcat gagtgcctcc atcctcctca gcaagctgtt
     1261 tgatgaccta aagtgcgatg ctgagcggga gaacttccac cgactctgtg agaactacat
     1321 caggagctgg tttgaaggcc aagggctggc cgggaagctg cgagccatcc agacagtgtc
     1381 ctgccttctg cagggcccat gtgacgctgg caaccgggcc ttagagctga gcggtgtcat
     1441 ggagagtgtg atcgctctct gcgcctcaga gcaggaggaa gaacagctgg tggcagtgga
     1501 agcactgatc catgcagccg gcaaagccaa gcgagcctca tttatcactg ccaatggcgt
     1561 cgcgctgctc aaggacctgt acaagggcag tgagagggac agcatccgca tcagagcact
     1621 agtgggactc tgtaagctcg gatcagctgg agggactgac tttagcatga agcagtttgc
     1681 tgaaggctct actctcaaac tggccaagca gtgccgaaag tggctatgca atgaccagat
     1741 tgatgcgggt actcggcgct gggcagtgga gggcctggcg tacctcacct ttgacgctga
     1801 tgtgaaggaa gagtttgtgg aggacgaggc tgctctgaag gccctgttcc agctcagcag
     1861 gtctgaagag aggtcggtac tctttgccgt aggctcggcc ctggtcaatt gcaccaacag
     1921 ctatgactat gaggagcctg accccaagat ggtggagctg gctaagtatg ccaagcagca
     1981 cgtgcctgaa cagcacccca aggacaaacc aagcttcgtg cgggctcgtg tgaagaagct
     2041 gctggcagcg ggtgtggtgt cagccatgac gtgtatggtg aagacggaga gcccagtgct
     2101 gacgaactcc tgtagggagc tactctccag ggtcttcctg gctttggtgg aagaggtgga
     2161 ggatcgaggt accgtggttg cccagggagg gggcaaggcc ctgctcccgc tggccctgga
     2221 gggcaccgac gtcgggcaga cgaaggcagc acaggctctt gctaagctca ccatcacctc
     2281 caacccagag atgacctttc ctggtgagcg gatctacgaa gtagtccggc cccttgtctc
     2341 tctgctgcac ctcagttgct caggactgca gaactttgag gccctcatgg ccctaacgaa
     2401 cctggccggg atcagtgaga ggcttagaca gaagatcctg aaggagaagg ccgtgcccat
     2461 gattgagggc tacatgtttg aggagcatga gatgatccgc cgggcagcta cagagtgcat
     2521 gtgtaactta gccatgagca aagaggtaca ggatctcttc gaagcccagg gcaacgaccg
     2581 gttgaagctg ctggtgctgt acagcggaga agatgatgag cttctgcgga gggctgctgc
     2641 cggtggcctg gccatgctca cctccatgcg gccctcactc tgcagccgta tcccacaagt
     2701 gaccacgcac tggctggaga tcctgcaggc cctgcttctg agccccaatc cggagctgca
     2761 gcaccggggc actgtcgtgg tgctgaacat gatggagtcc tcgaaggaga tcgccagcac
     2821 cctgatggag agcgaggtcc tggagatcct gtcagtgttg gccaagggcg aggagagccc
     2881 agtcaccagg gctgctgcag cctgtctgga gaaagccgtg gaatatagac ttatccaacc
     2941 caaccaggat ggggagtgag gttctgccct ggacccacag ctcatgtgtc tgctacccat
     3001 cacagctctg agagtcagga tagaagcagc gtggccaaca ggactgggat gctggacact
     3061 ggccttcctc cccagctgca ctttggtgtt ctctatcctg gggacacgca ccacacagcc
     3121 ctgccctgcc agcactcaga agggccctgt ctgtactgta gagagctggg aatggggagc
     3181 acgcatccca ttcaagtctg tggattatgg gcatcaagaa ggaagggcac agtagcatcc
     3241 tcacaagccg ggagcatcac cagagcctgc cagcaggcta gtccctctaa taaatcatgt
     3301 ggaactaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//
