LOCUS       NM_173146               7250 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Rattus norvegicus unc-13 homolog C (Unc13c), mRNA.
ACCESSION   NM_173146 XM_003750535
VERSION     NM_173146.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7250)
  AUTHORS   Kawabe,H., Mitkovski,M., Kaeser,P.S., Hirrlinger,J., Opazo,F.,
            Nestvogel,D., Kalla,S., Fejtova,A., Verrier,S.E., Bungers,S.R.,
            Cooper,B.H., Varoqueaux,F., Wang,Y., Nehring,R.B.,
            Gundelfinger,E.D., Rosenmund,C., Rizzoli,S.O., Sudhof,T.C.,
            Rhee,J.S. and Brose,N.
  TITLE     ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a
            specific subset of active zones
  JOURNAL   J Cell Biol 216 (4), 1143-1161 (2017)
   PUBMED   28264913
  REMARK    Erratum:[J Cell Biol. 2017 Apr 3;216(4):1205. doi:
            10.1083/jcb.20160608603092017c.. PMID: 28289090]
REFERENCE   2  (bases 1 to 7250)
  AUTHORS   Chen,Z., Cooper,B., Kalla,S., Varoqueaux,F. and Young,S.M. Jr.
  TITLE     The Munc13 proteins differentially regulate readily releasable pool
            dynamics and calcium-dependent recovery at a central synapse
  JOURNAL   J Neurosci 33 (19), 8336-8351 (2013)
   PUBMED   23658173
REFERENCE   3  (bases 1 to 7250)
  AUTHORS   Lipstein,N., Schaks,S., Dimova,K., Kalkhof,S., Ihling,C.,
            Kolbel,K., Ashery,U., Rhee,J., Brose,N., Sinz,A. and Jahn,O.
  TITLE     Nonconserved Ca(2+)/calmodulin binding sites in Munc13s
            differentially control synaptic short-term plasticity
  JOURNAL   Mol Cell Biol 32 (22), 4628-4641 (2012)
   PUBMED   22966208
REFERENCE   4  (bases 1 to 7250)
  AUTHORS   Augustin,I., Korte,S., Rickmann,M., Kretzschmar,H.A., Sudhof,T.C.,
            Herms,J.W. and Brose,N.
  TITLE     The cerebellum-specific Munc13 isoform Munc13-3 regulates
            cerebellar synaptic transmission and motor learning in mice
  JOURNAL   J Neurosci 21 (1), 10-17 (2001)
   PUBMED   11150314
REFERENCE   5  (bases 1 to 7250)
  AUTHORS   Augustin,I., Betz,A., Herrmann,C., Jo,T. and Brose,N.
  TITLE     Differential expression of two novel Munc13 proteins in rat brain
  JOURNAL   Biochem J 337 (Pt 3) (Pt 3), 363-371 (1999)
   PUBMED   9895278
REFERENCE   6  (bases 1 to 7250)
  AUTHORS   Brose,N., Hofmann,K., Hata,Y. and Sudhof,T.C.
  TITLE     Mammalian homologues of Caenorhabditis elegans unc-13 gene define
            novel family of C2-domain proteins
  JOURNAL   J Biol Chem 270 (42), 25273-25280 (1995)
   PUBMED   7559667
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            U75361.1.
            
            On Nov 22, 2013 this sequence version replaced NM_173146.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U75361.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132266,
                                           SAMD00132272 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-7250              U75361.1           15-7264
FEATURES             Location/Qualifiers
     source          1..7250
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..7250
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /note="unc-13 homolog C"
                     /db_xref="GeneID:286931"
                     /db_xref="RGD:628592"
     exon            1..3006
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     CDS             54..6668
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /note="Munc13-3; protein unc-13 homolog C-like"
                     /codon_start=1
                     /product="protein unc-13 homolog C"
                     /protein_id="NP_775169.4"
                     /db_xref="GeneID:286931"
                     /db_xref="RGD:628592"
                     /translation="MVASLFKSLILAYIHKLCKGMFTKKLGNTTKKKENRQQNKDQDF
                     PTAGHTKPPKLSNALKSTVKKIAKCSSTRNFSVEDEEGHKDFSLSPTFSYRVAIANGL
                     QTAVTNSDEDLLQELSSIESSYSESFNELRSSTENQVQSTHTMPVRRNRKSSSSLAPS
                     EGSSDGERTLHTLKLGALRKLRKWKKSQECVSSDSELSTVKKTWGIRSKSLDRTARNP
                     KTNVLEPGFSSSGCISQTHDVMEMIFKELQGISQIETELSELRGHVNALKYSIDEISS
                     SVEVVQSEIEQLRTGFVQARRETRDIHDYIKHLGHMGSKVSLRFLNVPEERHEYVESV
                     VYQILVDKMGFSDVPNAIKIEFAQRIGQQRDCPNAKPRPILVYFETPQQRDSVLKKSY
                     KLKGTGIAISTDILTYDIRERKEKGVLPSSQTYESMDMKLSTPEPKAKKNAWLSPNDS
                     DRELESDLSRSSYADSPAKGSSSKSSSKSHSARSKNKAANSRTSQKSDYNKRPSKPPA
                     SEKPTPHYVEATPLWHSQSDFFTPKLSRSESDFSKLCQSYSEDFSESQFFCRTNGSSL
                     LSSSDRELWQRKQEGMTALYHSPQDQGLDGNIPTVPGQGEIENTETVDSGMSNSVVCA
                     SGDRSNYSGSQLSLHEDLSPWKEWNQAGHGTDGLDSSTQEPFDYDTNSLSDQQLDMSS
                     KDLDDLGKCHSDLQDDSESYDLTQDDNSSPCPGLDNEPQGQWVGQYDSYQKTNSNDLY
                     PNQSHPSMMYRSQSELQSDDSEAAQPKSWHSRLSIDLSDKTFKFPKFGSTLQRAKSAL
                     EVVWNKSTQSLSGCEDSGSSLMGRFRTLSQSTANESSTTLDSDIYTEPYYYKAEEEED
                     YCEPVADSETDYVEVMEQVLAKLENRTSVTEVDEHIKEYDHPSYETPYETPQDEGYDG
                     QADDIISEGELETLNEPAVEMELVEDESQNLPVEPPEVMKPKRIRPSFKEAALRAYKK
                     QMAELEEKILAGDSSSVDEKARIVSGNDLDASKFSALQVFGGAGRGLYGIDSMPDLRR
                     KKTLPIVRDVAMTLAARKSGLSLAMVIRTSLNNEELKMHVFRKTLQALIYPISSTTPH
                     NFEVWTATTPTYCYECEGLLWGIARQGMKCLECGVKCHEKCQDLLNADCLQRAAEKSS
                     KHGAEDKTQTIITAMKERMKIRERNRPEVFEVIQEMFQISKEDFVQYTKAAKQSVLDG
                     TSKWSAKITITVVSAQGLQAKDKTGSSDPYVTVQVGKNKRRTKTIFGNLNPVWDEKFY
                     FECHNSTDRIKVRVWDEDDDIKSRVKQHFKKESDDFLGQTIVEVRTLSGEMDVWYNLE
                     KRTDKSAVSGAIRLKINVEIKGEEKVAPYHIQYTCLHENLFHYLTEVKSNGSVKIPEV
                     KGDEAWKVFFDDASQEIVDEFAMRYGVESIYQAMTHFSCLSSKYMCPGVPAVMSALLA
                     NINAFYAHTTVSTNVQVSASDRFAATNFGREKFIKLLDQLHNSLRIDLSKYRENFPAS
                     NSERLQDLKSTVDLLTSITFFRMKVLELQSPPKASAVVKDCVRACLDSTYKYIFDNCH
                     ELYSQLIDPSKKQDVPREEQGPTTKNLDFWPQLITLMVTIIDEDKTAYTPVLNQFPQE
                     LNMGKISAEIMWSLFALDMKYALEEHEKQRLCKSTDYMNLHFKVKWFYNEYVRELPAF
                     KDAVPEYSLWFEPFVMQWLDENEDVSMEFLHGALGRDKKDGFQQTSDHALFSCSVVDV
                     FAQLNQSFEIIKKLECPNPEALSHLMRRFAKTINKVLVQYAAIVSSDFSSYCDKETVP
                     CILMNNIQQLRVQLEKMFESMGGKELDPEASTILKELQIKLNGVLDALSVTYGESFQL
                     VIEECIKQMGAELNQMRANGNSAANKNNAAMDAEIVLRPLMDFLDKILSLSAKICEKT
                     VLKRVLKELWKLVLNKIEKQIVLPPLTDQTGPQMIFIAAKELGQLSKLKEHMIRDDAK
                     GLTPRQCAIMEVVLATIKQYFHAGGNGLKKNFLEKSPDLHSLRYALSLYTQTTDALIK
                     KFIETQGSQSRSSKDAVGQISVHVDVTTTPGTGEHKVTVKVIAINDLNWQTTTMFRPF
                     VEVCMLGPSLGDKKRKQGTKTKSNTWSPKYNETFQFILGNENRPGAYELHLSVKDYCF
                     AREDRIIGMTVIQLQNIAEKGSYGAWYPLLKNLSMDETGLTILRILSQRTSDDVAKEF
                     VRLKSETRSIDESA"
     exon            3007..3029
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            3030..3094
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            3095..3173
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            3174..3179
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            3180..3251
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            3252..3471
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            3472..3699
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            3700..3841
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            3842..4011
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            4012..4127
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            4128..4291
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            4292..4448
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            4449..4517
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            4518..4607
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            4608..4736
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            4737..4870
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            4871..4956
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            4957..5083
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            5084..5180
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            5181..5324
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            5325..5402
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            5403..5480
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            5481..5569
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            5570..5719
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            5720..5843
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            5844..5900
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            5901..5981
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            5982..6129
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            6130..6222
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            6223..6382
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
     exon            6383..7250
                     /gene="Unc13c"
                     /gene_synonym="Unc13h3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccagtgcctt gttcacttcc ctggattaga aaagctcaca ctcattgctc tccatggtgg
       61 ctagtctctt taagagcttg attttagctt atatacataa gctttgcaaa ggaatgttta
      121 caaagaaatt gggaaataca accaaaaaga aagaaaatcg tcagcagaat aaagatcaag
      181 atttccctac tgctggccac accaaacccc ctaaattgtc caatgccctg aaaagcactg
      241 taaaaaagat tgcaaagtgc tcatccaccc gtaacttctc cgtagaagac gaagaaggtc
      301 acaaagactt ctccctgtca cccacattca gttaccgagt tgctatcgcc aatggcctgc
      361 aaacagctgt gaccaacagt gatgaggacc tgcttcagga gctgtcttcc attgagagct
      421 catactctga atccttcaat gagctaagga gcagcactga aaaccaggtt cagtcaaccc
      481 acaccatgcc ggtcaggcgt aacaggaaga gctcaagcag cttggcaccc tccgagggca
      541 gctcagatgg ggagcgcacc ctccacacct taaaactggg tgctctacgg aagctgagga
      601 aatggaagaa gagccaagag tgtgtctcct cagactcgga gttgagcact gtgaagaaaa
      661 cctggggtat aagaagcaaa tctttagata gaactgctcg gaacccaaag accaatgttt
      721 tggagccagg gttcagctcc tctggctgta ttagccaaac ccatgatgtc atggaaatga
      781 tctttaaaga gcttcagggt ataagtcaga ttgaaacaga actttctgaa ctccgaggcc
      841 atgtaaatgc tctcaagtac tctatcgatg aaatctccag cagtgtggag gttgtccaga
      901 gtgagattga acagcttcgg acaggatttg tccaggctcg aagggaaact agagatatcc
      961 acgattacat taaacacttg ggtcacatgg ggagtaaagt aagcctgaga tttttaaatg
     1021 tgcctgaaga aagacatgaa tatgtggaaa gtgtggtgta ccaaattctt gtagataaaa
     1081 tgggtttctc tgatgtaccg aatgctatta aaattgaatt tgctcagagg atagggcaac
     1141 aaagggattg cccaaacgca aaacctcgac ccatcctagt gtactttgaa acccctcagc
     1201 aaagggattc tgtcttaaag aaatcataca agctcaaagg cacaggcatt gcgatctcca
     1261 cagatattct aacttatgat atcagagaac ggaaagagaa aggggtatta ccatcttctc
     1321 agacatatga aagcatggat atgaagttat ccacaccaga gcccaaagcc aagaagaatg
     1381 cttggctgtc acccaatgac agtgacagag agctggagtc agaccttagc agaagcagct
     1441 atgctgactc tccagcaaag ggaagttctt ctaagtccag ctcaaagtca cacagcgctc
     1501 ggtctaagaa caaagcagct aacagcagaa cgtcacagaa gtcggactac aacaaacggc
     1561 catccaaacc gccagcatca gaaaagccaa cacctcacta tgtggaagcc acaccactct
     1621 ggcattcaca gagtgacttc ttcactccta aacttagtcg ctctgaatca gatttttcca
     1681 aattgtgtca gtcttactca gaggattttt ctgaaagtca gtttttctgt agaactaatg
     1741 ggagctccct cctttcctct tctgaccgag agctttggca gaggaaacag gagggtatga
     1801 ctgccttgta ccacagtcct caggaccagg gtttagatgg gaatattcct acagtaccag
     1861 ggcagggtga aattgagaat acagaaacag tggacagtgg tatgagcaac agtgtggtgt
     1921 gtgcatctgg agaccgaagc aattatagtg gttcccagct ctcactgcat gaggacctgt
     1981 ctccatggaa ggagtggaat caagcagggc acggaactga tggtttagat tcatctaccc
     2041 aggaaccttt tgactatgac accaacagtt tatctgacca acagttggac atgtctagca
     2101 aagacctaga tgaccttggc aagtgccaca gtgacctgca agatgactca gagagctatg
     2161 atttaaccca ggatgacaac tcttctccat gccctggatt ggataatgaa ccacaaggcc
     2221 agtgggttgg ccagtatgat tcttatcaga aaaccaactc taatgacctg taccccaacc
     2281 aaagccatcc atccatgatg tatcgaagtc aaagtgaatt gcaaagcgat gattccgagg
     2341 cggcccagcc caagtcctgg cacagtcggc taagcattga cctttctgac aagaccttta
     2401 agttccccaa atttggatcc actcttcaga gggcgaagtc agccctggaa gtggtgtgga
     2461 acaagagcac acagagtctc agtgggtgtg aggacagcgg ctcttcctta atggggagat
     2521 ttcggacatt gtctcagtcc acggcaaatg agtcaagtac cacccttgac tctgatatct
     2581 acacagaacc ctattactat aaagctgagg aagaggagga ctactgtgaa ccagtggctg
     2641 acagtgagac ggattatgtt gaagtgatgg agcaggtcct agctaagcta gaaaacagga
     2701 ctagtgtgac tgaagtagat gaacacatta aagagtacga ccacccttcc tatgaaactc
     2761 cttatgagac cccacaagat gagggttatg atgggcaggc tgatgacatc attagtgaag
     2821 gagaactgga aaccttaaat gagccagcag ttgaaatgga attagtagaa gatgaaagcc
     2881 aaaacctccc tgtagagcca ccagaggtca tgaagccaaa gagaatccga ccttccttca
     2941 aagaagcagc tttaagggct tataagaagc agatggcaga gctggaagag aagatcctgg
     3001 ctggagacag cagctccgtg gatgaaaagg ctcgaatagt aagtggcaac gatttggatg
     3061 cttccaaatt ctccgcactc caggtgttcg gtggggctgg gcgtggactt tacggaatag
     3121 acagcatgcc tgatctccgc aggaaaaaga cactgcctat tgtacgggat gtggccatga
     3181 ccctggctgc ccggaaatct ggtctatccc ttgctatggt tatcaggaca tccctgaaca
     3241 atgaggagct gaaaatgcat gtcttccgga agaccttgca ggcattgatc taccccattt
     3301 cttctaccac tcctcacaac ttcgaggtct ggacagctac cacacccacc tactgctatg
     3361 agtgtgaagg gctgctgtgg ggcattgcaa ggcaaggcat gaagtgtctg gagtgtgggg
     3421 tgaaatgtca cgagaagtgt caggacctgc tcaacgccga ctgtctgcag cgagcagcgg
     3481 agaagagctc taagcatggt gcagaggaca agacgcagac catcatcaca gccatgaaag
     3541 aaagaatgaa gatcagggag aggaacaggc cagaggtgtt tgaagtcatt caggaaatgt
     3601 tccagatctc caaagaggat tttgtgcagt acacaaaggc tgccaagcag agcgtgctag
     3661 atggcacgtc caagtggtca gcgaaaataa ccatcacagt ggtttctgca caaggcttgc
     3721 aggcaaaaga caaaacaggg tccagtgacc catatgtgac agttcaagtt ggcaagaata
     3781 aaagaagaac gaaaactatc tttggaaact tgaatccggt gtgggatgag aagttctact
     3841 ttgagtgtca taactcgaca gaccgaatca aggtcagagt gtgggatgaa gacgacgaca
     3901 ttaaatccag agtgaagcaa cacttcaaga aggagtcaga tgactttctg ggacagacga
     3961 ttgtcgaagt caggactctg agtggcgaga tggatgtctg gtacaactta gagaaacgga
     4021 cagataaatc agctgtgtct ggggccatcc gactaaaaat caatgtggaa ataaagggag
     4081 aggagaaggt tgcaccgtat catatacaat acacttgttt acacgagaac ctgttccatt
     4141 acctgacaga agtgaagtct aatggcagcg tgaaaatacc agaggtcaaa ggcgatgaag
     4201 cctggaaggt tttctttgat gatgcttctc aagaaatagt ggatgaattt gccatgcgtt
     4261 atggggttga gtccatttat caagctatga cgcacttttc atgtctgtct tctaagtaca
     4321 tgtgcccggg tgtccctgca gtcatgagcg ccctgctggc gaacatcaat gccttctatg
     4381 ctcatacaac tgtctccact aacgtgcagg tttctgcttc tgatcgcttt gctgctacga
     4441 actttgggag ggaaaaattc ataaaactac tggaccagtt gcataactcc ttaaggattg
     4501 atctgtcaaa atacagggaa aactttccag ccagcaacag tgagagacta caggacctaa
     4561 agtccactgt ggacctgctg accagcatca ccttcttccg gatgaaggtc ctggagctgc
     4621 agagcccccc aaaggccagc gcagtggtga aggattgtgt cagggcttgt ctggattcca
     4681 cgtacaagta tatcttcgac aactgccacg aactctattc tcagctgata gacccgagca
     4741 agaagcagga tgttcctcgg gaagagcagg gaccaaccac caagaacctg gacttctggc
     4801 cacagttgat tacactgatg gtcactatca ttgatgagga taagactgcc tacacccctg
     4861 ttctcaatca gttcccacaa gaactaaaca tggggaagat aagtgcagaa atcatgtggt
     4921 ctctctttgc tctcgatatg aaatatgctc tagaggaaca tgagaagcag cgcttatgca
     4981 agagcaccga ttatatgaat ttgcatttca aagtgaaatg gttttataat gagtatgtac
     5041 gagaacttcc tgccttcaag gatgctgttc cagaatattc cctgtggttt gagccttttg
     5101 ttatgcaatg gctagatgaa aatgaagatg tgtccatgga attccttcat ggagcactgg
     5161 gaagagacaa aaaggatgga ttccagcaga catcggacca tgccctcttc tcctgttctg
     5221 tggttgatgt ctttgctcag cttaaccaga gctttgagat cattaagaaa ctggaatgcc
     5281 ccaatcctga agccttatca cacttaatga gacgattcgc aaagaccatc aataaggttc
     5341 tggtccaata cgctgcgatc gtatcaagtg acttcagttc atactgtgat aaggagacag
     5401 tgccttgcat attgatgaac aacatccaac aactgcgggt ccagctggaa aagatgttcg
     5461 aatccatggg tgggaaagag ctagaccccg aagctagcac tattctgaaa gaacttcaaa
     5521 tcaaactcaa cggggttctg gatgcgctca gcgtcactta tggagaaagt ttccaacttg
     5581 taattgaaga gtgcataaag cagatgggtg ccgagctaaa tcagatgcga gcaaacggaa
     5641 acagcgcagc caataagaac aacgcagcga tggatgcgga gattgtgctg aggccgctca
     5701 tggacttctt ggataagata ttaagtcttt cagcaaaaat ctgtgagaaa acggtcctga
     5761 agcgagttct gaaggagctc tggaaattag ttcttaacaa gatagagaaa cagattgttc
     5821 tccctccact gacagaccag acaggacctc agatgatctt cattgcagct aaagagcttg
     5881 gacagttatc caaactgaag gagcacatga tccgagatga tgccaagggt ctgacaccaa
     5941 gacaatgtgc aataatggag gtggtcctgg ccactataaa gcaatacttt catgcaggag
     6001 gaaatggcct gaagaagaat tttctggaga aaagcccaga tcttcattcc ctgagatacg
     6061 ctctcagcct ctacacacaa accactgatg ctttgatcaa gaagttcatc gagacccagg
     6121 gctcacagag tcgttcctcc aaagatgctg taggccagat ctctgtccat gtggatgtca
     6181 ccaccacccc agggactgga gagcataaag tcactgtaaa agtgattgcg atcaatgacc
     6241 taaactggca gaccaccacc atgttccgcc cctttgtgga agtgtgcatg ctgggaccca
     6301 gcctgggaga caagaagaga aaacaaggga caaagacaaa aagtaacacg tggtcaccga
     6361 agtacaatga aaccttccag ttcattctgg gtaatgagaa ccgcccagga gcctatgaac
     6421 ttcacctctc agttaaggac tactgctttg cccgagaaga tcgaataatt ggaatgacag
     6481 tcattcagtt acagaatata gcagagaaag ggagctacgg ggcatggtac cctctcctga
     6541 aaaatctctc tatggatgaa actggtttaa ccatccttcg aatactctct cagagaacca
     6601 gtgacgatgt cgctaaagag tttgtgagac ttaagtctga aacgaggtct attgacgaga
     6661 gtgcctgaaa catagacttc caaatactat ctttgagaat tcataaactc ccattgtgtg
     6721 acccttacat gcatgtgaaa atacatggga atgtttaaac ccactgcgtt ttgatgtttg
     6781 ccagtaatca accacaatgt ctacaatgta tgtaaacaac ttttatatca gttctggtct
     6841 ttgagaaata aatgttccat gaagtgccaa aattatgatg taaagtgaaa tatcaaggta
     6901 atcttttaca atgttcttct cattaccaat ttcttctcca tgaagaaaac taaaatacat
     6961 tcttgagttt gtccattggt tgtctttgtt agattaattt agagcgacct atcagaaagc
     7021 atttttgact gaacttcttc tgttccgttc agccttacct tattgtagac accctgcaga
     7081 tccagttttc taccacactt agaaatgcag caacttctag aaagtttgta attttatagt
     7141 tgcagatata ttgtgatgat ttttgcatac aaattacaat agaaaaggtg ggaaatattt
     7201 tatgctgacc agttcctaac ctttctaaaa tatcactgtg aagaaatgct
//
