LOCUS       NM_001024743            2138 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus UDP-glucose pyrophosphorylase 2 (Ugp2), mRNA.
ACCESSION   NM_001024743 XM_214108
VERSION     NM_001024743.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2138)
  AUTHORS   Wang,J., Huo,K., Ma,L., Tang,L., Li,D., Huang,X., Yuan,Y., Li,C.,
            Wang,W., Guan,W., Chen,H., Jin,C., Wei,J., Zhang,W., Yang,Y.,
            Liu,Q., Zhou,Y., Zhang,C., Wu,Z., Xu,W., Zhang,Y., Liu,T., Yu,D.,
            Zhang,Y., Chen,L., Zhu,D., Zhong,X., Kang,L., Gan,X., Yu,X., Ma,Q.,
            Yan,J., Zhou,L., Liu,Z., Zhu,Y., Zhou,T., He,F. and Yang,X.
  TITLE     Toward an understanding of the protein interaction network of the
            human liver
  JOURNAL   Mol Syst Biol 7, 536 (2011)
   PUBMED   21988832
  REMARK    Erratum:[Mol Syst Biol. 2017 Dec 18;13(12):965. doi:
            10.15252/msb.20178107. PMID: 29254952]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2138)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   3  (bases 1 to 2138)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   4  (bases 1 to 2138)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   5  (bases 1 to 2138)
  AUTHORS   Aw,T.Y. and Jones,D.P.
  TITLE     Control of glucuronidation during hypoxia. Limitation by
            UDP-glucose pyrophosphorylase
  JOURNAL   Biochem J 219 (3), 707-712 (1984)
   PUBMED   6331395
REFERENCE   6  (bases 1 to 2138)
  AUTHORS   Guynn,R.W., Veloso,D., Lawson,J.W. and Veech,R.L.
  TITLE     The concentration and control of cytoplasmic free inorganic
            pyrophosphate in rat liver in vivo
  JOURNAL   Biochem J 140 (3), 369-375 (1974)
   PUBMED   4374936
REFERENCE   7  (bases 1 to 2138)
  AUTHORS   Knop,J.K. and Hansen,R.G.
  TITLE     Uridine diphosphate glucose pyrophosphorylase. IV. Crystallization
            and properties of the enzyme from human liver
  JOURNAL   J Biol Chem 245 (10), 2499-2504 (1970)
   PUBMED   5427280
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC097369.1.
            
            [WARNING] On Oct 26, 2024 this sequence was replaced by
            NM_001024743.2.
            
            On Jun 10, 2005 this sequence version replaced XM_214108.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097369.1, SRR8487227.306088.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMEA5760494
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2138
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q22"
     gene            1..2138
                     /gene="Ugp2"
                     /note="UDP-glucose pyrophosphorylase 2"
                     /db_xref="GeneID:289827"
                     /db_xref="RGD:1310210"
     exon            1..267
                     /gene="Ugp2"
                     /inference="alignment:Splign:2.1.0"
     CDS             249..1775
                     /gene="Ugp2"
                     /EC_number="2.7.7.9"
                     /codon_start=1
                     /product="UTP--glucose-1-phosphate uridylyltransferase"
                     /protein_id="NP_001019914.1"
                     /db_xref="GeneID:289827"
                     /db_xref="RGD:1310210"
                     /translation="MSRFVQDLSKAMSQDGASQFQEVILQELELSVKKELEKILTTAT
                     SHEFEHTKKDLDGFRKLFHRFLQEKGPSVDWGKIQRPPEDSIQPYEKIKARGLPDNIS
                     SVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLV
                     LMNSFNTDEDTKKILQKYNHCRVKIYTFNQSRYPRINKESLLPIAKDVSYSGENTEAW
                     YPPGHGDIYASFYNSGLLDTFIEEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKRC
                     EFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWI
                     SLAAVKRLQEQNAIDMEIIVNPKTLDGGLNVIQLETAVGAAIKSFENSLGINVPRSRF
                     LPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIP
                     DMLELDHLTVSGDVTFGKNVSLKGTVIIIANHGDRIDIPPGAVLENKIVSGNLRILDH
                     "
     exon            268..395
                     /gene="Ugp2"
                     /inference="alignment:Splign:2.1.0"
     exon            396..503
                     /gene="Ugp2"
                     /inference="alignment:Splign:2.1.0"
     exon            504..689
                     /gene="Ugp2"
                     /inference="alignment:Splign:2.1.0"
     exon            690..823
                     /gene="Ugp2"
                     /inference="alignment:Splign:2.1.0"
     exon            824..1121
                     /gene="Ugp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..1319
                     /gene="Ugp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1320..1562
                     /gene="Ugp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1563..1667
                     /gene="Ugp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1668..2113
                     /gene="Ugp2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgggatcgct gagtagccag gagttccctc ccaagctgag tcggtcccac caagtttccg
       61 tcttctggat ttttcttttt aaagaccagt tttgatcccc cccccctccc gaatacttcc
      121 ttaagtagct aaacagcgga ggagaaagaa cacttcggtt gttgcaggga agggagagag
      181 acctttctta caacgcagct tctagaaatt gaaaattata aggcagatta ttttaataaa
      241 atcctaaaat gtcgagattt gtacaagatc ttagcaaagc tatgtctcaa gatggtgctt
      301 ctcagttcca agaggtcatt ctccaagaac tagaattatc tgtgaagaaa gaattagaaa
      361 aaatacttac cacagcaacc tcacatgagt ttgagcacac taagaaagat cttgatggat
      421 ttcggaagct atttcacaga tttttgcaag aaaaggggcc ttctgtagac tggggtaaaa
      481 tccagagacc tccggaagat tcgattcaac cctatgaaaa gataaaggcc agaggcttgc
      541 ctgataacat atcttctgtg ttgaacaaac tggtggtagt gaaactcaat ggtggtttgg
      601 gaaccagcat gggctgcaaa ggccctaaaa gtctgattgg tgtaagaaat gagaatacct
      661 ttttggatct aaccgttcag caaattgaac atctgaacaa aacctataat acagatgtcc
      721 cgctcgtatt aatgaattct tttaacacgg atgaggatac aaaaaaaata ctccagaagt
      781 acaatcattg tcgtgtgaaa atctacacct tcaatcaaag caggtacccg aggattaata
      841 aggaatctct acttcctata gcaaaggacg tatcttattc aggggaaaat actgaagctt
      901 ggtaccctcc aggacatggg gacatctatg ccagtttcta caactctggt ttgctcgaca
      961 ccttcataga agaaggcaag gagtatattt ttgtgtctaa catagacaac ctgggtgcca
     1021 cagtggatct ttatattctt aatcatctaa tgaacccacc caatgggaaa cgctgtgaat
     1081 ttgtcatgga agtcacaaat aaaacacggg cagacgtaaa gggtgggaca ctcactcagt
     1141 acgaaggcaa actgaggctg gtggagattg ctcaggtgcc caaagcacac gttgatgagt
     1201 tcaagtctgt gtcaaaattt aaaatattta acacaaacaa cctatggatc tccctggccg
     1261 ccgttaaaag actgcaggaa cagaatgcta ttgacatgga aatcattgtg aacccaaaga
     1321 cattggatgg aggcctgaat gttattcagt tagaaactgc agttggagcg gcaattaaaa
     1381 gtttcgagaa ttctttaggt attaatgttc caaggagtcg ttttctgcct gtgaaaacca
     1441 catcagatct cttacttgtg atgtcaaacc tctacagcct taacgcagga tctttgacca
     1501 tgagtgaaaa gcgtgaattt cctacggtac ctttggttaa attaggcagt tcttttacca
     1561 aggttcaaga ttatctaaga aggtttgaaa gtatacccga tatgttggaa ctggaccacc
     1621 tcacggtttc aggagatgta acatttggaa aaaatgtttc attaaaggga acagttatca
     1681 tcattgcaaa tcatggtgac agaattgaca tccccccagg agcagtgtta gagaacaaga
     1741 ttgtatctgg gaaccttcgg atcctggacc actgaaatga gcactgtcag ctacactttc
     1801 tactaattat gggctaaaga gttttacaat aaaatgtcct cagattataa agcaagcagg
     1861 tactttattt actatgttgt actctgcact attgattttt aaagtagttt tctgcaatga
     1921 gcttttagtc taaggaaagc ctaaacaaag caatactttc cttcttggat gaaaagccta
     1981 gaaattaggt cctcttaaag tgcaatatta tttaatctca gaatcgggcc agctctgtag
     2041 atcttcaaca gaagcttcag tgactgtccc tttgaattgc ctttgatttc aaaaataaaa
     2101 agatccatgt gttaaaaaaa aaaaaaaaaa aaaaaaaa
//
