LOCUS       NM_001014142            1539 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus UFM1-specific peptidase 2 (Ufsp2), mRNA.
ACCESSION   NM_001014142 XM_341436
VERSION     NM_001014142.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1539)
  AUTHORS   Yoo,H.M., Kang,S.H., Kim,J.Y., Lee,J.E., Seong,M.W., Lee,S.W.,
            Ka,S.H., Sou,Y.S., Komatsu,M., Tanaka,K., Lee,S.T., Noh,D.Y.,
            Baek,S.H., Jeon,Y.J. and Chung,C.H.
  TITLE     Modification of ASC1 by UFM1 is crucial for ERalpha transactivation
            and breast cancer development
  JOURNAL   Mol Cell 56 (2), 261-274 (2014)
   PUBMED   25219498
REFERENCE   2  (bases 1 to 1539)
  AUTHORS   Ha,B.H., Jeon,Y.J., Shin,S.C., Tatsumi,K., Komatsu,M., Tanaka,K.,
            Watson,C.M., Wallis,G., Chung,C.H. and Kim,E.E.
  TITLE     Structure of ubiquitin-fold modifier 1-specific protease UfSP2
  JOURNAL   J Biol Chem 286 (12), 10248-10257 (2011)
   PUBMED   21228277
REFERENCE   3  (bases 1 to 1539)
  AUTHORS   Kang,S.H., Kim,G.R., Seong,M., Baek,S.H., Seol,J.H., Bang,O.S.,
            Ovaa,H., Tatsumi,K., Komatsu,M., Tanaka,K. and Chung,C.H.
  TITLE     Two novel ubiquitin-fold modifier 1 (Ufm1)-specific proteases,
            UfSP1 and UfSP2
  JOURNAL   J Biol Chem 282 (8), 5256-5262 (2007)
   PUBMED   17182609
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083771.1.
            
            On Apr 20, 2005 this sequence version replaced XM_341436.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083771.1, SRR8487226.17675.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1539
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q11"
     gene            1..1539
                     /gene="Ufsp2"
                     /gene_synonym="RGD1311161"
                     /note="UFM1-specific peptidase 2"
                     /db_xref="GeneID:361151"
                     /db_xref="RGD:1311161"
     exon            1..39
                     /gene="Ufsp2"
                     /gene_synonym="RGD1311161"
                     /inference="alignment:Splign:2.1.0"
     exon            40..126
                     /gene="Ufsp2"
                     /gene_synonym="RGD1311161"
                     /inference="alignment:Splign:2.1.0"
     CDS             63..1448
                     /gene="Ufsp2"
                     /gene_synonym="RGD1311161"
                     /EC_number="3.4.22.-"
                     /codon_start=1
                     /product="ufm1-specific protease 2"
                     /protein_id="NP_001014164.1"
                     /db_xref="GeneID:361151"
                     /db_xref="RGD:1311161"
                     /translation="MDILFRIRGGFDLAFQLAPPKEMFIKNALRQVLNDLTTKLSSDA
                     LVFRICNSSVYLWPNSDANTGELTDSSACKSVVDLIQFDQEEDTKRKFMKKKDKKLTD
                     MQQIVNIDLMLEISTPLGAVTPIIERENEEHHYINMSLPIDAVVSVAPEETWGKVRKL
                     LVDAILNQLVDVEKCILRYMKGTSIVVPEPLHFLLPGGKNLVTVLYPSGIPDDQLQAY
                     RKELHDLFKLPHDRPYLKRINAYHFPDELYKDGYIRNPHAYLSPPNIEGSMICMVQGT
                     YAYHHYMQNRVDDNGWGCAYRSLQTVCSWFRHQGYTERAIPTHREIQQALVDAGDKPA
                     TFVGSRQWIGSIEVQLVLNQLIGVTSKILFVNQGSEMASQGRELANHFQNVGTPVMIG
                     GGVLAHTILGVAWNETTGQIKFLILDPHYTGAEDLQVILEKGWCGWKGPDFWNKDAYY
                     NLCLPQRPNAL"
     exon            127..304
                     /gene="Ufsp2"
                     /gene_synonym="RGD1311161"
                     /inference="alignment:Splign:2.1.0"
     exon            305..371
                     /gene="Ufsp2"
                     /gene_synonym="RGD1311161"
                     /inference="alignment:Splign:2.1.0"
     exon            372..529
                     /gene="Ufsp2"
                     /gene_synonym="RGD1311161"
                     /inference="alignment:Splign:2.1.0"
     exon            530..722
                     /gene="Ufsp2"
                     /gene_synonym="RGD1311161"
                     /inference="alignment:Splign:2.1.0"
     exon            723..869
                     /gene="Ufsp2"
                     /gene_synonym="RGD1311161"
                     /inference="alignment:Splign:2.1.0"
     exon            870..1034
                     /gene="Ufsp2"
                     /gene_synonym="RGD1311161"
                     /inference="alignment:Splign:2.1.0"
     exon            1035..1159
                     /gene="Ufsp2"
                     /gene_synonym="RGD1311161"
                     /inference="alignment:Splign:2.1.0"
     exon            1160..1236
                     /gene="Ufsp2"
                     /gene_synonym="RGD1311161"
                     /inference="alignment:Splign:2.1.0"
     exon            1237..1361
                     /gene="Ufsp2"
                     /gene_synonym="RGD1311161"
                     /inference="alignment:Splign:2.1.0"
     exon            1362..1516
                     /gene="Ufsp2"
                     /gene_synonym="RGD1311161"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcacgaagta ggtgttcttg ccttcgccag tggttcctgg tggtttcccc aaactatgat
       61 ctatggatat cctcttcaga ataagaggtg gtttcgatct ggcttttcag ctggcgcctc
      121 ctaaagaaat gtttatcaag aatgcactaa gacaggtatt gaatgacctg actaccaagc
      181 tctcctcaga tgctcttgtg ttcagaattt gcaacagctc tgtgtacctc tggccgaaca
      241 gtgacgcaaa cacgggagaa ctgactgaca gctctgcctg taagagtgta gtggacctca
      301 ttcaatttga tcaagaggag gatacaaagc gaaaattcat gaaaaagaaa gacaaaaagt
      361 taaccgacat gcaacaaata gtaaatatag acctcatgct ggaaatatcg acccctctgg
      421 gagccgtaac ccccatcatc gaaagggaaa acgaagaaca ccactacatt aatatgagct
      481 tgccaatcga tgcggttgtg tccgttgctc cagaggaaac atggggaaaa gtgcgcaaac
      541 ttctagtgga tgcaattctt aatcagctag ttgatgtgga aaaatgcatc ttgagatata
      601 tgaaaggaac atctattgtg gtccctgaac cactgcactt tctattgcca gggggaaaga
      661 atctcgtaac agttttatat ccatccggaa tcccagatga tcagctacaa gcctatagaa
      721 aggagttaca tgatctcttc aaattgcctc atgacagacc ttatctcaaa aggattaatg
      781 cttatcactt tccggatgaa ctatataaag atggctatat tagaaatccg catgcttacc
      841 tgagcccacc taacatagag ggtagtatga tttgcatggt ccagggcact tacgcctatc
      901 atcactacat gcaaaatcgg gtggacgaca acggctgggg ctgtgcttac aggtcactac
      961 agacggtctg ctcatggttc agacatcagg gttacacaga aagggccatt ccaacacaca
     1021 gggaaatcca gcaggctcta gttgatgccg gtgacaaacc agcaacattt gttggatcac
     1081 ggcaatggat cgggtctatt gaagtgcagc tggtactaaa ccaactgatc ggtgtaactt
     1141 ccaaaatact gtttgtcaat caaggttcag aaatggcttc tcaaggacgg gaactagcca
     1201 accatttcca gaatgtgggc actccagtaa tgattggggg aggagtattg gctcacacaa
     1261 tactaggagt cgcatggaat gaaactacag ggcagatcaa attcctaatt ctagacccac
     1321 actatacagg tgctgaagac ctgcaagtta tattggaaaa gggctggtgt ggatggaagg
     1381 gtccagactt ttggaacaag gatgcatact acaacttatg ccttcctcaa cgaccaaatg
     1441 ctctttaaat taccttggtg tcaagactat aaatataaaa gagctgttcc aatgttaata
     1501 aaagcataat tttaaaaaaa aaaaaaaaaa aaaaaaaaa
//
