LOCUS       NM_001034829            1050 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus UBX domain protein 1 (Ubxn1), mRNA.
ACCESSION   NM_001034829 XM_006230975
VERSION     NM_001034829.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1050)
  AUTHORS   LaLonde,D.P. and Bretscher,A.
  TITLE     The UBX protein SAKS1 negatively regulates endoplasmic
            reticulum-associated degradation and p97-dependent degradation
  JOURNAL   J Biol Chem 286 (6), 4892-4901 (2011)
   PUBMED   21135095
REFERENCE   2  (bases 1 to 1050)
  AUTHORS   Wu-Baer,F., Ludwig,T. and Baer,R.
  TITLE     The UBXN1 protein associates with autoubiquitinated forms of the
            BRCA1 tumor suppressor and inhibits its enzymatic function
  JOURNAL   Mol Cell Biol 30 (11), 2787-2798 (2010)
   PUBMED   20351172
REFERENCE   3  (bases 1 to 1050)
  AUTHORS   Alexandru,G., Graumann,J., Smith,G.T., Kolawa,N.J., Fang,R. and
            Deshaies,R.J.
  TITLE     UBXD7 binds multiple ubiquitin ligases and implicates p97 in
            HIF1alpha turnover
  JOURNAL   Cell 134 (5), 804-816 (2008)
   PUBMED   18775313
REFERENCE   4  (bases 1 to 1050)
  AUTHORS   Ishibashi,T., Ogawa,S., Hashiguchi,Y., Inoue,Y., Udo,H., Ohzono,H.,
            Kato,A., Minakami,R. and Sugiyama,H.
  TITLE     A novel protein specifically interacting with Homer2 regulates
            ubiquitin-proteasome systems
  JOURNAL   J Biochem 137 (5), 617-623 (2005)
   PUBMED   15944415
  REMARK    GeneRIF: Specific interaction of rat protein 2B28 with rat Homer2
            may play a role in regulation of protein degradation by
            ubiquitin-proteasome systems and that this function may be specific
            to Homer2 proteins among Homer family proteins.
REFERENCE   5  (bases 1 to 1050)
  AUTHORS   McNeill,H., Knebel,A., Arthur,J.S., Cuenda,A. and Cohen,P.
  TITLE     A novel UBA and UBX domain protein that binds polyubiquitin and VCP
            and is a substrate for SAPKs
  JOURNAL   Biochem J 384 (Pt 2), 391-400 (2004)
   PUBMED   15362974
REFERENCE   6  (bases 1 to 1050)
  AUTHORS   Hoja,M.R., Wahlestedt,C. and Hoog,C.
  TITLE     A visual intracellular classification strategy for uncharacterized
            human proteins
  JOURNAL   Exp Cell Res 259 (1), 239-246 (2000)
   PUBMED   10942595
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Oct 5, 2022 this sequence version replaced
            XM_006230975.3, NM_001034829.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22582416.822879.1,
                                           SRR26643289.3846.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-36                JAXUCZ010000001.1  215194418-215194453
            37-122              JAXUCZ010000001.1  215194539-215194624
            123-176             JAXUCZ010000001.1  215194728-215194781
            177-283             JAXUCZ010000001.1  215194870-215194976
            284-353             JAXUCZ010000001.1  215195079-215195148
            354-545             JAXUCZ010000001.1  215196166-215196357
            546-597             JAXUCZ010000001.1  215196447-215196498
            598-714             JAXUCZ010000001.1  215196824-215196940
            715-907             JAXUCZ010000001.1  215197833-215198025
            908-1050            JAXUCZ010000001.1  215198201-215198343
FEATURES             Location/Qualifiers
     source          1..1050
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..1050
                     /gene="Ubxn1"
                     /gene_synonym="2B28; RGD1309471"
                     /note="UBX domain protein 1"
                     /db_xref="GeneID:293719"
                     /db_xref="RGD:1309471"
     exon            1..36
                     /gene="Ubxn1"
                     /gene_synonym="2B28; RGD1309471"
                     /inference="alignment:Splign:2.1.0"
     exon            37..122
                     /gene="Ubxn1"
                     /gene_synonym="2B28; RGD1309471"
                     /inference="alignment:Splign:2.1.0"
     CDS             64..957
                     /gene="Ubxn1"
                     /gene_synonym="2B28; RGD1309471"
                     /note="SAPK substrate protein 1"
                     /codon_start=1
                     /product="UBX domain-containing protein 1"
                     /protein_id="NP_001030001.2"
                     /db_xref="GeneID:293719"
                     /db_xref="RGD:1309471"
                     /translation="MAELTALESLIEMGFPRGRAEKALALTGNQGIEAAMDWLMEHED
                     DPDVDEPLETPLSHILGREPTPSEQVGPEGSGSAAGESKPVLTEEERQEQTKRMLELV
                     AQKQREREEREEREALEREKQRRRQGQELSAARQKLQEDEIRRAAEERRREKAEELAA
                     RQRVREKIERDKAERAQKYGGTVGSRSSPPATDPGPVPSSPRQEPPTKREYDQCRIQV
                     RLPDGTSLTQTFRAREQLAAVRLYVELHRGEEPGQDQDPVQLLSGFPRRAFSEADMER
                     PLQELGLVPSAVLIVAKKCPS"
     exon            123..176
                     /gene="Ubxn1"
                     /gene_synonym="2B28; RGD1309471"
                     /inference="alignment:Splign:2.1.0"
     exon            177..283
                     /gene="Ubxn1"
                     /gene_synonym="2B28; RGD1309471"
                     /inference="alignment:Splign:2.1.0"
     exon            284..353
                     /gene="Ubxn1"
                     /gene_synonym="2B28; RGD1309471"
                     /inference="alignment:Splign:2.1.0"
     exon            354..545
                     /gene="Ubxn1"
                     /gene_synonym="2B28; RGD1309471"
                     /inference="alignment:Splign:2.1.0"
     exon            546..597
                     /gene="Ubxn1"
                     /gene_synonym="2B28; RGD1309471"
                     /inference="alignment:Splign:2.1.0"
     exon            598..714
                     /gene="Ubxn1"
                     /gene_synonym="2B28; RGD1309471"
                     /inference="alignment:Splign:2.1.0"
     exon            715..907
                     /gene="Ubxn1"
                     /gene_synonym="2B28; RGD1309471"
                     /inference="alignment:Splign:2.1.0"
     exon            908..1050
                     /gene="Ubxn1"
                     /gene_synonym="2B28; RGD1309471"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtgtctaca ccccccgtcc ccgggtcccc cgcccggtcc ccgcggtagc ggaggcgggc
       61 gccatggcgg agctgacggc tctggagagc ctcatcgaga tgggctttcc caggggacgc
      121 gcggagaagg ctctggccct cacagggaac cagggcatcg aggctgcgat ggactggctt
      181 atggagcatg aagacgaccc cgatgtggac gagcctctag agactcctct cagccatatc
      241 ctgggacgag aacccacgcc ctcagagcaa gttggtcctg aaggatctgg gtctgctgct
      301 ggagaaagca aacccgtttt gactgaagag gagaggcaag aacagactaa gagaatgttg
      361 gaacttgtgg cgcagaagca gcgggaacgt gaagaaagag aggagcgaga agctttagaa
      421 cgagagaagc agcggaggag acaagggcaa gagctgtcag ctgcacgaca gaaactacag
      481 gaagatgaga tacgccgggc tgctgaggag cgcaggaggg agaaggctga agagctagct
      541 gccagacaaa gggttcgaga gaaaattgaa agggacaaag cagagagagc ccagaagtat
      601 ggtggtaccg tgggttctcg gtcatcccca ccagcaacag atccaggtcc tgttccttct
      661 tctccccgcc aggagccccc tacgaagagg gagtatgacc agtgtcgcat acaggttagg
      721 ctgcctgatg ggacttcact gacccaaacc ttccgggccc gggagcagct ggcagctgtg
      781 aggctctatg tggagcttca ccgaggggag gaacctggac aggaccagga cccggtgcag
      841 ttgctcagtg gcttccccag acgggctttc tcagaggctg acatggaacg gcctctgcag
      901 gaactgggac tcgtgccttc tgctgtcctc attgtggcca agaagtgtcc cagctgaggg
      961 tcctccatcc caccatctct gtctgacctc ttcatctttg ataaagcact gacatttcct
     1021 tcctaataaa tagacccttt gagttctgta
//
