LOCUS       NM_001007705            3274 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ubiquitin protein ligase E3 component n-recognin
            7 (Ubr7), mRNA.
ACCESSION   NM_001007705 XM_234475
VERSION     NM_001007705.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3274)
  AUTHORS   Liu,S., Liu,H., Gong,C., Li,G., Li,Q., Pan,Z., He,X., Jiang,Z.,
            Li,H. and Zhang,C.
  TITLE     MiR-10b-5p Regulates Neuronal Autophagy and Apoptosis Induced by
            Spinal Cord Injury Through UBR7
  JOURNAL   Neuroscience 543, 13-27 (2024)
   PUBMED   38382692
  REMARK    GeneRIF: MiR-10b-5p Regulates Neuronal Autophagy and Apoptosis
            Induced by Spinal Cord Injury Through UBR7.
REFERENCE   2  (bases 1 to 3274)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   3  (bases 1 to 3274)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC081966.1.
            
            On Nov 29, 2004 this sequence version replaced XM_234475.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC081966.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3274
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q32"
     gene            1..3274
                     /gene="Ubr7"
                     /gene_synonym="RGD1359144"
                     /note="ubiquitin protein ligase E3 component n-recognin 7"
                     /db_xref="GeneID:314399"
                     /db_xref="RGD:1359144"
     exon            1..177
                     /gene="Ubr7"
                     /gene_synonym="RGD1359144"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..1305
                     /gene="Ubr7"
                     /gene_synonym="RGD1359144"
                     /EC_number="2.3.2.27"
                     /note="ubiquitin protein ligase E3 component n-recognin 7
                     (putative)"
                     /codon_start=1
                     /product="putative E3 ubiquitin-protein ligase UBR7"
                     /protein_id="NP_001007706.1"
                     /db_xref="GeneID:314399"
                     /db_xref="RGD:1359144"
                     /translation="MAGAESPTGCQAELEPVVSLVDVLEEDEELENEACAVLGGSDSE
                     KCSYSQGSVKRQALYACSTCTPEGEEPAGICLACSYECHGSHKLFELYTKRNFRCDCG
                     NSKFKNLECKLFPDKSKVNSCNKYNDNFFGLYCICKRPYPDPEDEVPDEMIQCVVCED
                     WFHGRHLGAIPPESGDFQEMVCQSCMRRCSFLWAYAAQLAVTRLPAEDDGLLLNAVGM
                     GDQDVIKPANGAHQDKTLKENVPEQGRDADKEVKAERNDEPCTSSSSEAHLQTVFKNE
                     NIKTEPQSGCRLQELQAKQFLKKDAATYWPLNWRSRLCTCQDCMKMYGDLDVLFLTDE
                     CDTVLAYENKGKSDQATDRRDPLMDTLSSMNRVQQVELICEYNDLKTELKDYLKRFAD
                     EGTVVKREDIQQFFEEFQSKKRRRVDGLQYYCS"
     exon            178..311
                     /gene="Ubr7"
                     /gene_synonym="RGD1359144"
                     /inference="alignment:Splign:2.1.0"
     exon            312..372
                     /gene="Ubr7"
                     /gene_synonym="RGD1359144"
                     /inference="alignment:Splign:2.1.0"
     exon            373..468
                     /gene="Ubr7"
                     /gene_synonym="RGD1359144"
                     /inference="alignment:Splign:2.1.0"
     exon            469..522
                     /gene="Ubr7"
                     /gene_synonym="RGD1359144"
                     /inference="alignment:Splign:2.1.0"
     exon            523..628
                     /gene="Ubr7"
                     /gene_synonym="RGD1359144"
                     /inference="alignment:Splign:2.1.0"
     exon            629..837
                     /gene="Ubr7"
                     /gene_synonym="RGD1359144"
                     /inference="alignment:Splign:2.1.0"
     exon            838..987
                     /gene="Ubr7"
                     /gene_synonym="RGD1359144"
                     /inference="alignment:Splign:2.1.0"
     exon            988..1150
                     /gene="Ubr7"
                     /gene_synonym="RGD1359144"
                     /inference="alignment:Splign:2.1.0"
     exon            1151..1212
                     /gene="Ubr7"
                     /gene_synonym="RGD1359144"
                     /inference="alignment:Splign:2.1.0"
     exon            1213..3250
                     /gene="Ubr7"
                     /gene_synonym="RGD1359144"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcagcggag cccggtgaca gttgaggatg gccggagccg agagtcccac cgggtgccag
       61 gcggagctgg agcccgtggt gtcgctggtg gacgtgctcg aggaagacga ggagctggag
      121 aatgaggcgt gcgccgtctt gggcggcagc gactccgaga agtgctccta ctcgcagggc
      181 tcagtgaaga gacaagcact atatgcctgt agcacctgca cgccagaggg agaagagcca
      241 gcaggcattt gtctggcttg cagttatgag tgtcatggaa gtcataaact atttgaactg
      301 tacacaaaaa gaaattttcg ttgtgattgt ggaaacagca agtttaaaaa tttggaatgc
      361 aaattatttc ctgacaaatc aaaggtaaat tcttgcaata agtacaatga caactttttt
      421 ggcttatact gcatttgtaa gagaccttat cctgatcctg aagatgaggt tccagatgag
      481 atgatacagt gtgtggtctg tgaagactgg ttccatggca ggcatcttgg tgccattccc
      541 cctgagagtg gggatttcca ggagatggtg tgccagtctt gtatgaggcg ctgttctttt
      601 ttgtgggctt atgctgccca gttggcagtc accagattac ctgctgaaga tgatgggctg
      661 ctgctgaatg ctgttgggat gggagatcaa gatgttatca agcctgcaaa tggagctcac
      721 caagataaga ccctgaaaga gaatgttcca gaacagggaa gggatgctga caaggaggtg
      781 aaagctgagc ggaatgacga gccctgcacc agctccagct ctgaggctca cctccagaca
      841 gtatttaaga atgaaaatat caaaaccgag cctcagtctg gctgcagact tcaggaactc
      901 caagccaaac agtttctaaa gaaagatgct gccacctatt ggcccttgaa ctggcgcagc
      961 cgactgtgca cctgccaaga ctgtatgaaa atgtatggag acctagacgt cctgttcctg
     1021 acagatgaat gtgacacagt tctggcttac gagaacaaag gcaagagtga ccaggcaact
     1081 gacagaaggg accctttaat ggacaccctc agcagcatga acagagtcca gcaagtggag
     1141 ctcatctgtg aatacaatga cttgaagact gaacttaagg attatctgaa gaggtttgct
     1201 gatgaaggca cggttgttaa gagagaagac attcagcagt tctttgaaga gtttcaatca
     1261 aaaaagagaa ggcgagtgga cgggctgcag tattactgca gctagagtgg agggctatgc
     1321 ttcctcagtc agcttcacgg aaatgccact gttccggaat aaagagacct gtgtcacact
     1381 tggttccctt tccatcctcc cgtggcctca ggcccccttc tccttaacag tagctgcagt
     1441 gtttacgctg gcctctcaac aagcatcctc tatgactcag ctcattccac cgactgcagc
     1501 tttcctgtcc aggataccca ggagtttgct tatgttttaa gaagtttgat ttgatcttga
     1561 gaaagcaaat tagcttcttt tttaacagtg tgttccatga cttccaaatg tgtgtccata
     1621 gagctattgc ttctgggtcc tctgtgtctt gcaggttctc ttcctgtcag cctgaacctc
     1681 tgtgggaaca accctctctg cccccatgat cacggtgcct tgggtcaaag cttcctcaag
     1741 cctgctctgc cagtgctctc agtgctttct gagatttgat catggcttga agtgatggga
     1801 actttcctct gtaccaaaca accttcagag tggccaggac tgatctgatt ggaggttgac
     1861 tggcaggatt gaggaaggga gcctttgttc tgagtttcgc tgattagttt aaagtgaaat
     1921 ttcattacca ttctaatggt cctcaaaccc cagtgttagt actgtaatgc tcctcgggct
     1981 tccgggaaac cactcatgtg agagcccctc tgctgctgcc tagaaatgac tagatcctac
     2041 ccttgacaag tgggtgcttt acagagtcct ctggtttctt acattatcag ggatatgcat
     2101 acgcatatat taaaaatgga cctattttga tactgttctg ttaggaaaat gttattggaa
     2161 ccctagtaag ttattttttc ccttgaatct gtgctaaagg caaagaagta tactgagtga
     2221 ccttagtggt ggtaagtggg gcagaggcag ccctgcaaga gagatggagg actccagcca
     2281 aagccctcag ttatatacac attgagtctt tgtatgcaaa cagtgtgccc agccactccc
     2341 cttcttgctg gtctgaaggt cttcctggat tgtataaaac cctgtgtttg agggaagtct
     2401 ttcagatggt atgaagtctt tttaaagttc cctcagtcta tgtggaaaca tcttttgatc
     2461 cacaaagacc taacttgtac cctcaagagg aacaaggtct tccctagcac actgagatac
     2521 attaaagaca ttttaggcca cgcgttggtg tgtgagcagc agttgtatgc atgaatactc
     2581 ttcaattcct ggacaagatg aagtagtcta caaataaggc ctcaggaaat ggcatggctc
     2641 ctgtactgtg taaagcctgc agccttctag tgacagatcc tgtgaagact gctacgtgga
     2701 gctggaaggt tcttcaggct gcaggcaaag cctgtgtgca ctgagctggc ctcctggata
     2761 gggctcagtt aaaaacctcc ggtgcctaca gcctagggat cctccaagtc tgaggttgtt
     2821 ttgaatttga gagttgcact tttcatgtta ccagcatgtt gtcctcaaaa tttgtatctt
     2881 cccagatatc agatttaact accaaaaagt tgtctgccct ttataggtca gcaccaaggt
     2941 gtagcagtag tgtcagtgag cagcaaaaat gcaaaccgcc attgttgaag ggcttgccta
     3001 agaaaggttc cccacttaac cagaaaacct ctttttgtac ctgttcacaa ctagttttct
     3061 tactattctc atagagatgg tttgggtcaa catgtggcag ttgatattaa tgcatgtttt
     3121 atgcagaaga aaatgtgata ccagttgctt ttaaggaatt ctggcattgt atgtacattt
     3181 ttgtagaaat tattactcaa catacttcaa tcaggtttct gtaaaatcca aattaaatca
     3241 attcaaaata aaaaaaaaaa aaaaaaaaaa aaaa
//
