LOCUS       NM_001419542           10771 bp    mRNA    linear   ROD 14-FEB-2025
DEFINITION  Rattus norvegicus ubiquitin protein ligase E3 component n-recognin
            5 (Ubr5), mRNA.
ACCESSION   NM_001419542 XM_039080163
VERSION     NM_001419542.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 10771)
  AUTHORS   Ding,F., Zhu,X., Song,X., Yuan,P., Ren,L., Chai,C., Zhou,W. and
            Li,X.
  TITLE     UBR5 oncogene as an indicator of poor prognosis in gastric cancer
  JOURNAL   Exp Ther Med 20 (5), 7 (2020)
   PUBMED   32934672
REFERENCE   2  (bases 1 to 10771)
  AUTHORS   Saurabh,K., Shah,P.P., Doll,M.A., Siskind,L.J. and Beverly,L.J.
  TITLE     UBR-box containing protein, UBR5, is over-expressed in human lung
            adenocarcinoma and is a potential therapeutic target
  JOURNAL   BMC Cancer 20 (1), 824 (2020)
   PUBMED   32867711
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 10771)
  AUTHORS   Wang,K., Tang,J., Liu,X., Wang,Y., Chen,W. and Zheng,R.
  TITLE     UBR5 regulates proliferation and radiosensitivity in human
            laryngeal carcinoma via the p38/MAPK signaling pathway
  JOURNAL   Oncol Rep 44 (2), 685-697 (2020)
   PUBMED   32468011
REFERENCE   4  (bases 1 to 10771)
  AUTHORS   Leboeuf,D., Abakumova,T., Prikazchikova,T., Rhym,L., Anderson,D.G.,
            Zatsepin,T.S. and Piatkov,K.I.
  TITLE     Downregulation of the Arg/N-degron Pathway Sensitizes Cancer Cells
            to Chemotherapy In Vivo
  JOURNAL   Mol Ther 28 (4), 1092-1104 (2020)
   PUBMED   32087767
REFERENCE   5  (bases 1 to 10771)
  AUTHORS   Seaborne,R.A., Hughes,D.C., Turner,D.C., Owens,D.J., Baehr,L.M.,
            Gorski,P., Semenova,E.A., Borisov,O.V., Larin,A.K., Popov,D.V.,
            Generozov,E.V., Sutherland,H., Ahmetov,I.I., Jarvis,J.C.,
            Bodine,S.C. and Sharples,A.P.
  TITLE     UBR5 is a novel E3 ubiquitin ligase involved in skeletal muscle
            hypertrophy and recovery from atrophy
  JOURNAL   J Physiol 597 (14), 3727-3749 (2019)
   PUBMED   31093990
  REMARK    GeneRIF: UBR5 is a novel E3 ubiquitin ligase involved in skeletal
            muscle hypertrophy and recovery from atrophy.
REFERENCE   6  (bases 1 to 10771)
  AUTHORS   Oughtred,R., Bedard,N., Adegoke,O.A., Morales,C.R., Trasler,J.,
            Rajapurohitam,V. and Wing,S.S.
  TITLE     Characterization of rat100, a 300-kilodalton ubiquitin-protein
            ligase induced in germ cells of the rat testis and similar to the
            Drosophila hyperplastic discs gene
  JOURNAL   Endocrinology 143 (10), 3740-3747 (2002)
   PUBMED   12239083
REFERENCE   7  (bases 1 to 10771)
  AUTHORS   Henderson,M.J., Russell,A.J., Hird,S., Munoz,M., Clancy,J.L.,
            Lehrbach,G.M., Calanni,S.T., Jans,D.A., Sutherland,R.L. and
            Watts,C.K.
  TITLE     EDD, the human hyperplastic discs protein, has a role in
            progesterone receptor coactivation and potential involvement in DNA
            damage response
  JOURNAL   J Biol Chem 277 (29), 26468-26478 (2002)
   PUBMED   12011095
REFERENCE   8  (bases 1 to 10771)
  AUTHORS   Callaghan,M.J., Russell,A.J., Woollatt,E., Sutherland,G.R.,
            Sutherland,R.L. and Watts,C.K.
  TITLE     Identification of a human HECT family protein with homology to the
            Drosophila tumor suppressor gene hyperplastic discs
  JOURNAL   Oncogene 17 (26), 3479-3491 (1998)
   PUBMED   10030672
REFERENCE   9  (bases 1 to 10771)
  AUTHORS   Huibregtse,J.M., Scheffner,M., Beaudenon,S. and Howley,P.M.
  TITLE     A family of proteins structurally and functionally related to the
            E6-AP ubiquitin-protein ligase
  JOURNAL   Proc Natl Acad Sci U S A 92 (7), 2563-2567 (1995)
   PUBMED   7708685
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 1995 May 23;92(11):5249. doi:
            10.1073/pnas.92.11.5249-b.. PMID: 7761480]
REFERENCE   10 (bases 1 to 10771)
  AUTHORS   Muller,D., Rehbein,M., Baumeister,H. and Richter,D.
  TITLE     Molecular characterization of a novel rat protein structurally
            related to poly(A) binding proteins and the 70K protein of the U1
            small nuclear ribonucleoprotein particle (snRNP)
  JOURNAL   Nucleic Acids Res 20 (7), 1471-1475 (1992)
   PUBMED   1533713
  REMARK    Erratum:[Nucleic Acids Res 1992 May 25;20(10):2624]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Apr 7, 2023 this sequence version replaced XM_039080163.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-473               JAXUCZ010000007.1  71109341-71109813   c
            474-518             JAXUCZ010000007.1  71076838-71076882   c
            519-600             JAXUCZ010000007.1  71076290-71076371   c
            601-677             JAXUCZ010000007.1  71075811-71075887   c
            678-797             JAXUCZ010000007.1  71074760-71074879   c
            798-987             JAXUCZ010000007.1  71068923-71069112   c
            988-1147            JAXUCZ010000007.1  71068593-71068752   c
            1148-1297           JAXUCZ010000007.1  71067885-71068034   c
            1298-1509           JAXUCZ010000007.1  71065112-71065323   c
            1510-1626           JAXUCZ010000007.1  71057161-71057277   c
            1627-1737           JAXUCZ010000007.1  71056963-71057073   c
            1738-1892           JAXUCZ010000007.1  71055725-71055879   c
            1893-2010           JAXUCZ010000007.1  71054857-71054974   c
            2011-2195           JAXUCZ010000007.1  71052807-71052991   c
            2196-2305           JAXUCZ010000007.1  71050753-71050862   c
            2306-2418           JAXUCZ010000007.1  71049835-71049947   c
            2419-2562           JAXUCZ010000007.1  71047781-71047924   c
            2563-2674           JAXUCZ010000007.1  71047585-71047696   c
            2675-2829           JAXUCZ010000007.1  71047212-71047366   c
            2830-3027           JAXUCZ010000007.1  71046618-71046815   c
            3028-3238           JAXUCZ010000007.1  71043738-71043948   c
            3239-3365           JAXUCZ010000007.1  71042247-71042373   c
            3366-3517           JAXUCZ010000007.1  71038388-71038539   c
            3518-3613           JAXUCZ010000007.1  71037887-71037982   c
            3614-3737           JAXUCZ010000007.1  71037403-71037526   c
            3738-3835           JAXUCZ010000007.1  71036637-71036734   c
            3836-3984           JAXUCZ010000007.1  71035425-71035573   c
            3985-4076           JAXUCZ010000007.1  71034891-71034982   c
            4077-4223           JAXUCZ010000007.1  71033519-71033665   c
            4224-4342           JAXUCZ010000007.1  71033311-71033429   c
            4343-4469           JAXUCZ010000007.1  71033101-71033227   c
            4470-4599           JAXUCZ010000007.1  71032882-71033011   c
            4600-4760           JAXUCZ010000007.1  71031682-71031842   c
            4761-5000           JAXUCZ010000007.1  71031342-71031581   c
            5001-5124           JAXUCZ010000007.1  71029657-71029780   c
            5125-5236           JAXUCZ010000007.1  71028982-71029093   c
            5237-5368           JAXUCZ010000007.1  71027504-71027635   c
            5369-5626           JAXUCZ010000007.1  71026937-71027194   c
            5627-5895           JAXUCZ010000007.1  71026173-71026441   c
            5896-6107           JAXUCZ010000007.1  71025803-71026014   c
            6108-6338           JAXUCZ010000007.1  71024071-71024301   c
            6339-6412           JAXUCZ010000007.1  71023343-71023416   c
            6413-6585           JAXUCZ010000007.1  71021486-71021658   c
            6586-6699           JAXUCZ010000007.1  71021289-71021402   c
            6700-6920           JAXUCZ010000007.1  71020141-71020361   c
            6921-7041           JAXUCZ010000007.1  71019050-71019170   c
            7042-7140           JAXUCZ010000007.1  71018851-71018949   c
            7141-7384           JAXUCZ010000007.1  71016933-71017176   c
            7385-7496           JAXUCZ010000007.1  71015181-71015292   c
            7497-7641           JAXUCZ010000007.1  71014530-71014674   c
            7642-7772           JAXUCZ010000007.1  71013607-71013737   c
            7773-7833           JAXUCZ010000007.1  71012374-71012434   c
            7834-8009           JAXUCZ010000007.1  71010465-71010640   c
            8010-8094           JAXUCZ010000007.1  71010009-71010093   c
            8095-8250           JAXUCZ010000007.1  71007706-71007861   c
            8251-8364           JAXUCZ010000007.1  71007356-71007469   c
            8365-8509           JAXUCZ010000007.1  71005782-71005926   c
            8510-8595           JAXUCZ010000007.1  71004296-71004381   c
            8596-10771          JAXUCZ010000007.1  71000197-71002372   c
FEATURES             Location/Qualifiers
     source          1..10771
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q22"
     gene            1..10771
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /note="ubiquitin protein ligase E3 component n-recognin 5"
                     /db_xref="GeneID:117060"
                     /db_xref="RGD:621236"
     exon            1..473
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     CDS             412..8808
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /EC_number="2.3.2.26"
                     /note="progestin-induced protein; hyperplastic discs
                     protein homolog; E3 ubiquitin-protein ligase, HECT
                     domain-containing 1; E3 ubiquitin-protein ligase
                     UBR5-like; HECT-type E3 ubiquitin transferase UBR5"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase UBR5"
                     /protein_id="NP_001406471.1"
                     /db_xref="GeneID:117060"
                     /db_xref="RGD:621236"
                     /translation="MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLE
                     QATIKQCVVGPNHAAFLLEDGRICRIGFSVQPDRLELGKPDNNDGSKLNSSSGTGRTS
                     RPGRTSDSPWFLSGSETLGRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRV
                     IRTGRDRGSGLLGSQPQPVIPASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNL
                     AVNNLLSRDDEDGDDGDDTASESYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDIS
                     YFGYPSFRRSSLSRLGSSRVLLLPLERDSELLRERESVLRLRERRWLDGASFDNERGS
                     TSKEGEPNPDKKNTPVQSPVSLGEDLQWWPDKDGTKFTCIGALYSELVAVSSKGELYQ
                     WKWTESEPYRNAQNPSLHHPRATFLGLTNEKIVLLSANSIRATVATENNKVATWVDET
                     LSSVASKLEHTAQTYSELQGERIVSLHCCALYTCAQLENNLYWWGVVPFSQRKKMLEK
                     ARAKNKKPKSSAGISSMPNITVGTQVCLRNNPLYHAGAVAFSISAGIPKVGVLMESVW
                     NMNDSCRFQLRSPESLKSMEKASKTIETKPESKQEPVKTEMGPPPSPASTCSDASSIA
                     SSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVEDVKNVPVGKVLKVDGAYVAVKF
                     PGTSSNTNCQNSSGPDADPSSLLQDCRLLRIDELQVVKTGGTPKVPDCFQRTPKKLCI
                     PEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQENNFPTSSVAFLGQNERS
                     VAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPPISSLGMGVHSLINLPA
                     NSTIKKKAAIIIMAVEKQTLMQHILRCDYEACRQYLVNLEQAVVLEQNLQMLQTFISH
                     RCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVEAIANAISVVSSN
                     GPGNRAGSSSSRSLRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPPIAPPSWVPDP
                     PSMDPDGDIDFILAPAVGSLTTAATGGGQGPSTSTIPGPSTEPSVVESKDRKANAHFI
                     LKLLCDSAVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIAKAEVSG
                     SEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCGLLES
                     LCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLTAT
                     NLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPDDSDMPDHDLE
                     PPRFAQLALERVLQDWNALRSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTI
                     RLDCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVF
                     VILSVEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPT
                     APFTLASTSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQ
                     PVRGREEEQDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGHHDEHDEDGS
                     DMELDLLAAAETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQS
                     NDSSDSDSSSSQSDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRA
                     ASTAPSSTSTPAASSAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSL
                     ARAYSIVIRQISDLMGLIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWM
                     VSIMDSTEAQLRYGSALASAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRR
                     ATLLSARQGMMSARGDFLNYALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWI
                     KAMNQQTTLDTPQLERKRTRELLELGIDNEDSEHENDDDTSQSATLNDKDDESLPAET
                     GQNHPFFRRSDSMTFLGCIPPNPFEVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGL
                     YSSSAGSGKCLVEVTMDRNCLEVLPTKMSYAANLKNVMNMQNRQKKAGEDQSMLAEEA
                     DSSKPGPSAHDVAAQLKSSLLAEIGLTESEGPPLTSFRPQCSFMGMVISHDMLLGRWR
                     LSLELFGRVFMEDVGAEPGSILTELGGFEVKESKFRREMEKLRNQQSRDLSLEVDRDR
                     DLLIQQTMRQLNNHFGRRCATTPMAVHRVKVTFKDEPGEGSGVARSFYTAIAQAFLSN
                     EKLPNLDCIQNANKGTHTSLMQRLRNRGERDREREREREMRRSSGLRAGSRRDRDRDF
                     RRQLSIDTRPFRPASEGNPSDDPDPLPAHRQALGERLYPRVQAMQPAFASKITGMLLE
                     LSPAQLLLLLASEDSLRARVEEAMELIVAHGRENGADSILDLGLLDSSEKVQENRKRH
                     GSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPGKNTEARLNCFRNIGRILGLC
                     LLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSSDADAVFSA
                     MDLAFAVDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMR
                     KGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRW
                     FWSIVERMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCISR
                     LYVPLYSSKQILKQKLLLAIKTKNFGFV"
     exon            474..518
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            519..600
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            601..677
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            678..797
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            798..987
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            988..1147
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            1148..1297
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            1298..1509
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            1510..1626
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            1627..1737
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            1738..1892
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            1893..2010
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            2011..2195
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            2196..2305
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            2306..2418
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            2419..2562
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            2563..2674
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            2675..2829
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            2830..3027
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            3028..3238
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            3239..3365
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            3366..3517
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            3518..3613
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            3614..3737
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            3738..3835
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            3836..3984
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            3985..4076
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            4077..4223
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            4224..4342
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            4343..4469
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            4470..4599
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            4600..4760
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            4761..5000
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            5001..5124
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            5125..5236
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            5237..5368
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            5369..5626
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            5627..5895
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            5896..6107
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            6108..6338
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            6339..6412
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            6413..6585
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            6586..6699
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            6700..6920
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            6921..7041
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            7042..7140
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            7141..7384
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            7385..7496
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            7497..7641
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            7642..7772
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            7773..7833
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            7834..8009
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            8010..8094
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            8095..8250
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            8251..8364
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            8365..8509
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            8510..8595
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
     exon            8596..10771
                     /gene="Ubr5"
                     /gene_synonym="Dd5; Rat100"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agaagtgaag atggcggcgg cggcgctggc ggcggcggtt cgtcgccagt gacgcgcgct
       61 gcgggctgct gtccctcccc gctccccgcg tccgccgcgt ccgccccggt acccctccac
      121 ccgcagcccg ccgctcgccg cgctccgggc cgccctcgtc cgtgcgcgcc gtggccggcc
      181 gagcgggcgg cgcgttgatc cgccctcccg cccgccgcgc cggaccgccg ggccgcggac
      241 acacgctcgg ctgggaggcg gcggtccctg cgcgctcgcg gccctccgtt tggggaccgg
      301 gaggaggagg cggtggcggc ggccgtggga tccggggacg ggaaggggat cggggggccg
      361 ggcgacagcg ggagcggctc gtccccggga gctgggcgcg caggcggtac catgacgtcc
      421 atccatttcg tggttcaccc gctgccgggc accgaggacc agctcaatga caggttgcgg
      481 gaagtttcgg agaagctgaa caagtacaat ctgaacagcc acccgccttt gaacgtactg
      541 gagcaggcca cgattaaaca gtgtgtcgtg gggcccaatc acgccgcgtt tcttcttgag
      601 gatggcagaa tttgtaggat tggtttttca gtacaaccag acagactgga attgggtaaa
      661 cctgataata atgatgggtc aaaactgaac agcagctcgg ggacagggag gacttctagg
      721 ccgggaagaa caagtgactc gccgtggttt ctctcaggtt ctgagactct gggcaggctg
      781 gcaggcaaca ctctgggaag ccgctggagt tctggagtcg gtggaagtgg aggaggctcc
      841 tctggtcggt cgtctgctgg agcccgtgat tcccggcgac agactcgagt cattcggact
      901 ggacgggatc ggggatctgg acttctgggc agtcagcctc agccagttat tccagcatct
      961 gtcattcctg aggagctgat ttcgcaggct caagttgttt tacaaggcaa atcaagaagt
     1021 gtcattattc gagaacttca gagaacaaat cttgatgtca accttgctgt aaataattta
     1081 ctgagccggg atgatgagga tggagatgac ggtgatgata cagccagtga atcttacctg
     1141 ccgggagaag accttatgtc ccttcttgat gctgacattc actctgccca cccaagtgtc
     1201 attattgatg ctgatgccat gttttctgag gacattagct attttggtta cccttctttt
     1261 cgtcgttcat cactctctag gctaggctca tctcgagttc tccttcttcc cttagagaga
     1321 gactccgagc ttttgcggga gcgggaatct gttctacgct tacgggaacg acggtggctt
     1381 gatggagcct catttgataa cgaaaggggc tctaccagca aagaaggaga gcccaacccg
     1441 gataagaaga acacgcctgt gcagagtcca gtgtctctgg gagaagactt acagtggtgg
     1501 cctgataagg atggaaccaa gtttacctgc attggggctc tgtattctga gcttgtggcg
     1561 gtcagcagta aaggagagct ttaccaatgg aagtggactg agtctgagcc ttacagaaat
     1621 gcccagaatc cttcattgca tcatccacga gcaacatttt tggggttgac caatgaaaag
     1681 atagtcctcc tgtctgcaaa tagcataaga gcaaccgtag ctactgaaaa taacaaggtt
     1741 gctacatggg tggatgaaac attaagttct gtggcttcta agttagaaca cacagcccag
     1801 acttactctg aacttcaagg agaacggata gtttctttac attgctgtgc cctttatacc
     1861 tgcgcccagc tggagaataa tttatattgg tggggtgttg ttccttttag tcaaaggaag
     1921 aaaatgttag agaaagctag agcaaaaaat aaaaagccca aatccagtgc tggtatttcc
     1981 tctatgccaa acatcactgt tggaactcag gtgtgcttaa gaaataaccc tctctatcat
     2041 gctggagcag tcgccttttc aattagtgct gggattccca aagttggtgt cttaatggag
     2101 tcagtctgga atatgaatga tagctgtaga tttcaacttc ggtctccaga gagcctgaaa
     2161 agcatggaaa aagccagcaa aactattgaa acaaagcctg agagtaagca ggaacctgtg
     2221 aaaacggaaa tgggtcctcc cccatcacca gcatccacct gcagcgatgc ttcctccatt
     2281 gccagcagcg catccatgcc atataaacga cgtcgatcaa ctcctgcccc aaaagaagag
     2341 gagaaggtga acgaagagca gtggtccctg cgggaagttg tttttgttga agatgttaag
     2401 aatgttcctg tcggcaaggt gctgaaggtg gatggcgcct atgtagctgt gaagtttcca
     2461 ggaacatcta gtaacaccaa ctgtcagaac agctctgggc cggatgctga cccgtcttca
     2521 ctcctgcagg actgcaggct acttcgaatc gatgagctgc aggttgtcaa aactggtggc
     2581 accccaaaag ttcctgactg tttccagagg actcccaaaa agctttgtat acctgagaag
     2641 actgaaatat tagcagtgaa tgtggattcc aaaggtgtac atgctgtttt gaagacggga
     2701 aactgggtac ggtactgtat ctttgatctt gctacaggaa aagctgaaca agaaaataat
     2761 tttccaacaa gcagcgttgc ttttcttggt cagaatgaga gaagtgtagc tattttcact
     2821 gctggacagg agtctcctat tattcttcgg gatggaaatg gtactatcta tccaatggcc
     2881 aaagactgta tgggaggaat aagggaccct gactggctcg atctcccacc aattagtagt
     2941 ctcgggatgg gtgtacattc tttaataaat cttcctgcca attcaacaat caaaaagaaa
     3001 gcagctatta tcatcatggc tgtagagaag caaactttaa tgcagcacat tctcagatgt
     3061 gactatgagg cctgccgaca gtatcttgtg aatctggagc aagcagttgt tttagagcag
     3121 aacctacaga tgttacagac gttcatcagc caccgatgtg atgggaaccg aaacatttta
     3181 catgcttgtg tatcagtttg ctttccaact agcaataagg aaactaaaga agaagaggaa
     3241 gctgagcgct cagaaagaaa tacatttgca gaaaggcttt ctgctgtgga ggccattgca
     3301 aatgcaatat cagttgtttc aagtaatggc ccaggtaatc gggctggatc atcaagtagt
     3361 cgaagtttga gattacggga aatgatgaga cggtcactga gagcagctgg tttgggtaga
     3421 catgaggctg gagcttcatc tagtgaccac caggacccag tttcaccccc catagctccc
     3481 cctagttggg ttcctgaccc tccttcaatg gatcctgatg gtgacattga ttttatcctg
     3541 gcccccgctg tgggatctct taccacagca gcgactggcg gtggtcaagg accaagcacc
     3601 tccaccattc caggtccttc cacagagcct tctgtagtag aatccaagga tcgaaaggca
     3661 aatgctcatt ttatattaaa attgctatgc gacagtgcag ttctgcagcc ttatctacga
     3721 gagcttcttt ctgccaagga tgccagaggg atgaccccat tcatgtctgc tgtaagtggc
     3781 cgggcctacc ctgctgcaat caccatctta gaaacagctc agaaaatcgc caaagctgag
     3841 gtatctggaa gtgaaaagga ggaagatgta tttatgggaa tggtttgccc gtcaggcacc
     3901 aatcctgacg actctccttt gtacgtctta tgttgtaatg acacctgcag ctttacgtgg
     3961 accggagcag aacacattaa ccaggacatt tttgagtgcc ggacttgtgg tttactggag
     4021 tcactttgtt gttgtacaga atgtgcaagg gtttgtcata aaggccacga ttgcaaactt
     4081 aagcggactt caccaacagc ttactgtgat tgttgggaga aatgtaagtg taaaacattg
     4141 attgctggac agaagtccgc tcggctcgat ctgctctatc gcctgctcac tgctaccaat
     4201 ctagtcaccc taccaaacag caggggagag cacctcttgc tgttcttagt gcagaccgtg
     4261 gccaggcaga cagtggagca ctgtcagtat aggcctccgc ggatcaggga ggatcgcaac
     4321 aggaaaacag ccagtcctga cgattcagac atgcccgacc atgacttaga gcccccacgg
     4381 tttgcacagc tcgccctgga acgtgtcctt caggactgga atgctttgag gtctatgatt
     4441 atgtttgggt cacaggagaa taaagaccct ctgagtgcca gcagtaggat aggtcatctt
     4501 ttgccagaag agcaggtgta cctcaatcag caaagtggca cgattcgact cgactgtttc
     4561 actcactgcc ttattgtcaa gtgtacagca gatattttgc ttttagatac tctactaggc
     4621 acattagtga aagaactcca aaacaaatac acacctggac gccgagaaga agcaattgct
     4681 gtaacaatga ggtttctacg atcagtggca agagtgtttg tcattcttag tgtggaaatg
     4741 gcttcatcca aaaagaaaaa caactttatt ccacagccaa ttggaaaatg caaacgtgtg
     4801 tttcaagcac tacttcctta cgctgtagaa gaattgtgta atgtagcaga gtctctgatt
     4861 gttcctgtca gaatggggat tgcccgccct acagccccgt ttacactggc cagtactagc
     4921 atagatgcta tgcaaggcag tgaagaatta ttttcagtag aaccattacc accacggcct
     4981 tcatcagatc agtcaagcag ctccagtcaa tctcagtcat cttacatcat ccggaatcca
     5041 cagcagaggc gcatcagcca gtcacagcct gtcagaggtc gggaggaaga acaggatgat
     5101 attgtgtcag cagatgtgga agaggttgag gtggtggaag gcgtggctgg agaggaggat
     5161 catcacgatg aacaggaaga gcatggggaa gagaacgctg aggctgaggg gcatcacgat
     5221 gaacatgatg aggacggaag tgacatggag ctagacttgt tagcagccgc tgagacggaa
     5281 agtgacagtg aaagtaacca tagtaaccaa gataatgcta gtgggcgcag aagtgttgtc
     5341 actgcagcca ctgcaggctc tgaggcagga gcgagcagtg ttcctgcctt tttttctgaa
     5401 gatgactctc agtcaaatga ctcaagtgac tccgacagta gtagcagtca gagtgatgac
     5461 atagagcagg agacctttat gctggatgag ccactagaga ggacaacgaa tagctcccat
     5521 gcgaacggtg ctgcccaggc ccctcgttcc atgcagtggg ctgtccggaa tacgcaacat
     5581 cagcgagcgg ctagcacagc tccgtccagt acatctacac cggcagcaag ttctgcaggt
     5641 ttgatttaca ttgatccttc aaatttacgc cggagcggca ccatcagtac aagtgctgcg
     5701 gcggcggcgg ctgctttgga agctagcaat gccagcagct acttaacatc ggccagcagt
     5761 ttagccaggg cttacagcat tgtcatcaga caaatctccg acttgatggg ccttattcct
     5821 aagtataatc acctagtata ctctcagatt ccagcagctg tgaaactgac ttaccaagat
     5881 gcagtcaact tacagaacta tgtagaagaa aagcttattc ctacgtggaa ctggatggtc
     5941 agtattatgg attctactga agctcaatta cgttatggtt ctgcattagc atctgctggt
     6001 gatccaggac atccaaatca tccccttcat gcctctcaga attcagctag aagagagagg
     6061 atgactgcac gagaagaggc cagtttaaga acacttgaag gcagacgacg tgccacattg
     6121 ctgagtgccc ggcagggaat gatgtctgct cgaggagatt ttctcaatta tgccctgtct
     6181 ttaatgagat ctcataatga tgagcattct gacgttcttc cagtgttgga tgtgtgctca
     6241 ttgaaacatg tggcatatgt ttttcaagcc cttatatatt ggattaaagc aatgaatcaa
     6301 cagacaactt tagacacccc tcaactggag cgcaaaagga cacgagaact tctggaactg
     6361 ggtattgata atgaagattc agaacacgag aatgatgatg acaccagtca aagcgctact
     6421 ttgaatgata aggatgatga atctcttcct gcagaaaccg gccaaaacca tccatttttc
     6481 cgacgttcag attctatgac attccttgga tgtatacctc caaatccatt tgaagtgcct
     6541 ttggctgaag ccatacccct ggctgatcag cctcatctgt tgcagccaaa tgctagaaag
     6601 gaagatctct ttggtcgccc aagtcagggt ctttattcgt catctgccgg tagcgggaaa
     6661 tgcttagtgg aagttacaat ggacagaaat tgtctcgagg ttcttccaac taaaatgtct
     6721 tatgctgcca atctaaaaaa tgtaatgaac atgcaaaacc ggcagaagaa agcaggggaa
     6781 gaccagagca tgctggccga agaggctgac agttcaaagc cagggccatc cgctcacgat
     6841 gttgccgccc agttgaaaag cagtttacta gcagagatag gactcacaga aagcgaaggg
     6901 cctcccctta catctttcag gccccagtgc agtttcatgg ggatggtgat ctctcatgac
     6961 atgctgctgg ggcgctggcg cctctcttta gaactgtttg gcagagtatt catggaagat
     7021 gttggagcgg agcctggatc gatcttaact gaattgggtg gttttgaggt aaaagaatca
     7081 aagttccgta gagagatgga aaaactgaga aaccagcaat caagagattt atcactagag
     7141 gttgatcgag atcgagatct tctcattcag cagactatga gacaactcaa caatcatttt
     7201 ggtcgaagat gtgctaccac accaatggct gtccacagag ttaaagtcac atttaaggat
     7261 gaaccaggag agggcagtgg tgtagcacgg agtttctata cagccattgc acaagccttt
     7321 ttatcaaatg aaaaattgcc aaatctagat tgtatccaaa atgccaacaa aggtactcat
     7381 acaagtttaa tgcaaagatt gaggaacaga ggcgagagag atcgggaaag agaaagagaa
     7441 cgggaaatga ggaggagcag tggcttgcga gcaggatctc ggagagaccg cgatcgagac
     7501 ttcaggagac agctgtccat cgacaccagg ccttttagac ctgcttctga ggggaaccct
     7561 agtgatgacc ctgaccctct tccagctcat cggcaggcac tcggagagag gctgtacccc
     7621 cgagtgcaag cgatgcagcc tgcctttgcc agtaaaatca ccggcatgct gctggagctg
     7681 tccccagctc agctgcttct ccttctggcg agtgaggact ctctgagggc gagagttgag
     7741 gaggccatgg agctcatcgt cgcccacgga cgggaaaatg gagctgacag tatcttggac
     7801 ctcggattat tagactcctc agaaaaggta caggaaaacc gaaagcgtca tggctctagc
     7861 agaagtgtgg tagatatgga tttagatgac accgatgatg gtgacgacaa tgctcctttg
     7921 ttttaccaac ctggaaagcg agggttttat actccgagac ctggcaaaaa cacagaagca
     7981 aggctgaatt gtttcagaaa catcggcagg attcttggac tatgtctgtt gcaaaatgaa
     8041 ctatgtccta tcacattgaa taggcatgta attaaagtgt tgcttggtag aaaagtcaac
     8101 tggcatgact ttgctttttt cgaccctgtg atgtatgaga gtttacgaca actgatcctt
     8161 gcatctcaga gttcagatgc cgatgctgtt ttctcagcaa tggacttggc gtttgcagtt
     8221 gacctgtgta aagaagaggg tggaggccag gttgaactta ttccaaatgg tgtaaatata
     8281 ccagtcactc cgcagaatgt atatgagtat gtaaggaaat atgcggagca cagaatgctg
     8341 gtggttgcag aacagccatt gcacgcaatg agaaagggtc tactagatgt gcttccaaaa
     8401 aattctttag aagacttaac agcagaggat ttccgacttt tggtgaacgg ctgtggtgaa
     8461 gtcaatgtgc agatgctcat cagtttcacg tctttcaatg atgagtcagg agagaatgct
     8521 gagaagctcc tgcagttcaa acgttggttc tggtcaatag tagagagaat gagcatgact
     8581 gagcggcagg acctggttta cttctggaca tcaagcccat cattgccagc cagtgaagaa
     8641 ggttttcagc ctatgccctc aatcacaata agaccaccag atgaccaaca tcttcctact
     8701 gcaaatactt gtatttctcg actttatgtc ccactctatt cctctaaaca gattctcaaa
     8761 caaaaattac tactcgccat taagaccaag aattttggtt ttgtgtagag tataaaaagt
     8821 gtgtattgct gtgtaatatt actagctaat tttgtagatt ttttttccca tttgtctata
     8881 aaagtttatg gaagttaatg ctgtcatacc cccctggtgg taccttacag agattaaatg
     8941 caaacattcc ttgctgagtt tgtagcttaa aggcctaaga agcactggca ccttttctct
     9001 atgatggttt gctagtcgcc aacttctagg tctaacccca gccaaagatg acagcagaac
     9061 aacataattt acactgtgat ttatcttttt tgctgagggg gaaaaaatgt aaaatgttct
     9121 gaaaattcac tgctgccttt gtggaaagtg tttcagcaaa ggttcttgta tagagggaat
     9181 agggaatttc aaaataaaaa attaagtatg ttctgtgttt tcattttaac ttttttatgg
     9241 tgttctttgt ggttggctgc aattgtgtat catgtatatg gaacttctag aaagttcttg
     9301 acattcagat tttagagacg aagtcacttt tacctataga aaacccactt gtgttgcggg
     9361 ttatttcagc ttcattgacc tttaggatac taaacaccac tgatatttta catgtaatgt
     9421 gttcctttga gagaggcact tttctgtaca tatgatgggc caatgcacag taccttatca
     9481 catccccttt tttgttttgt atctgttgta gtgcaggtgg acaggtcacg ctgcacttga
     9541 gtaacaacca gacatctgta tgaaggtgac tcagcctggg cactttctga taactgtaaa
     9601 atgttttata agatcatgat tactaaaaat acattttgga aaattttaaa tgttggtgag
     9661 cagcttaact acttttgtat ctagcctttt ttttaagtat cttgttacat tttacttttt
     9721 taaataaatt acagaagaaa tgtcaagtaa cattgaagat acagttttta tttacatagt
     9781 tgtacatttt ttaagctagg ggcaatgcac tgacatggtt atagtcatac ctttttttta
     9841 agtcatatac atgtgaacta taagaaagtt aagaaaatca gtccacattt tacagttagc
     9901 agagaatcct aagtggcacc cagccaggcc ttttcttttt acaaggtgaa gtgaagtgtg
     9961 attattaatc agcacagatg gtttgacttt aactaaggga caggtgtttt gttttgtttt
    10021 caaagactgt tgtctggaac caataccctt aacatttgtg gacttatcag gtttatttga
    10081 tgggataaca aggaataaaa agtccctact aggatttaaa ctagttactt aaatataaag
    10141 agaatagtga gagaagttgt tctgttgtct ctcacctatc ttttcagtgc ctgtttagga
    10201 cttctggcct ttgatagttt tcatgtttat aaagggacca tactctatta cataacttcc
    10261 tttaaaagac tgaatcacat ggcattctca gccctgttga cactaaagat ataaaatgta
    10321 tacagcacca tgctgtatta gatatatgta aacttaccaa agtgacacat tggtttatac
    10381 atctaaatat tacactgaat taagagctaa caaacatcaa tgtggctaaa aggaataaaa
    10441 caaacatacc ccttgtgtgc acttgacagg cttgataact tattaaatga gaacaagtta
    10501 aatatgatga ggacacttaa accctaatta agtttatttt taatagctat tgaaagaatg
    10561 aaaatattta aaataatgca atatttaaag tgcaagatgt ctgaggtctt ccattttagt
    10621 taaaatgctt ttagtaataa aaacatagta agattttttt gtttttaatt ttgtgtgtgc
    10681 atgagggttt tgttgttgtt gtgtgtgtgt gggttttttt ttttttcagt aaagcataaa
    10741 atggtctaaa tgtaaaataa agtcatataa a
//
