LOCUS       NM_001014117            2126 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus ubiquitin-like domain containing CTD phosphatase
            1 (Ublcp1), transcript variant 1, mRNA.
ACCESSION   NM_001014117 XM_340787
VERSION     NM_001014117.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2126)
  AUTHORS   Guo,X., Engel,J.L., Xiao,J., Tagliabracci,V.S., Wang,X., Huang,L.
            and Dixon,J.E.
  TITLE     UBLCP1 is a 26S proteasome phosphatase that regulates nuclear
            proteasome activity
  JOURNAL   Proc Natl Acad Sci U S A 108 (46), 18649-18654 (2011)
   PUBMED   21949367
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Apr 10, 2021 this sequence version replaced NM_001014117.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089210.1, SRR26643295.37529.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN12840105,
                                           SAMN12840106 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-71                JAXUCZ010000010.1  29462316-29462386   c
            72-268              JAXUCZ010000010.1  29459397-29459593   c
            269-360             JAXUCZ010000010.1  29458610-29458701   c
            361-446             JAXUCZ010000010.1  29458175-29458260   c
            447-562             JAXUCZ010000010.1  29457982-29458097   c
            563-661             JAXUCZ010000010.1  29456609-29456707   c
            662-699             JAXUCZ010000010.1  29454654-29454691   c
            700-798             JAXUCZ010000010.1  29454070-29454168   c
            799-915             JAXUCZ010000010.1  29451375-29451491   c
            916-1043            JAXUCZ010000010.1  29449604-29449731   c
            1044-2126           JAXUCZ010000010.1  29447081-29448163   c
FEATURES             Location/Qualifiers
     source          1..2126
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q21"
     gene            1..2126
                     /gene="Ublcp1"
                     /gene_synonym="RGD1310386"
                     /note="ubiquitin-like domain containing CTD phosphatase 1"
                     /db_xref="GeneID:360514"
                     /db_xref="RGD:1310386"
     exon            1..71
                     /gene="Ublcp1"
                     /gene_synonym="RGD1310386"
                     /inference="alignment:Splign:2.1.0"
     exon            72..268
                     /gene="Ublcp1"
                     /gene_synonym="RGD1310386"
                     /inference="alignment:Splign:2.1.0"
     CDS             115..1071
                     /gene="Ublcp1"
                     /gene_synonym="RGD1310386"
                     /EC_number="3.1.3.16"
                     /note="isoform 1 is encoded by transcript variant 1;
                     nuclear proteasome inhibitor UBLCP1"
                     /codon_start=1
                     /product="ubiquitin-like domain-containing CTD phosphatase
                     1 isoform 1"
                     /protein_id="NP_001014139.1"
                     /db_xref="GeneID:360514"
                     /db_xref="RGD:1310386"
                     /translation="MSLPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQK
                     LLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESLEDVLCPPPDNDDVINDFDIE
                     DEVVEVENREENLLKISRRVKEYKVEVLNPPREGKKLLVLDVDYTLFDHRSCAETGVE
                     LMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMIT
                     VHTPRRGLIDVKPLGVIWGKFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHL
                     NRDKDKELVKLTQYLKEIAKLDDFLELNHKYWERYLSKKQGQ"
     exon            269..360
                     /gene="Ublcp1"
                     /gene_synonym="RGD1310386"
                     /inference="alignment:Splign:2.1.0"
     exon            361..446
                     /gene="Ublcp1"
                     /gene_synonym="RGD1310386"
                     /inference="alignment:Splign:2.1.0"
     exon            447..562
                     /gene="Ublcp1"
                     /gene_synonym="RGD1310386"
                     /inference="alignment:Splign:2.1.0"
     exon            563..661
                     /gene="Ublcp1"
                     /gene_synonym="RGD1310386"
                     /inference="alignment:Splign:2.1.0"
     exon            662..699
                     /gene="Ublcp1"
                     /gene_synonym="RGD1310386"
                     /inference="alignment:Splign:2.1.0"
     exon            700..798
                     /gene="Ublcp1"
                     /gene_synonym="RGD1310386"
                     /inference="alignment:Splign:2.1.0"
     exon            799..915
                     /gene="Ublcp1"
                     /gene_synonym="RGD1310386"
                     /inference="alignment:Splign:2.1.0"
     exon            916..1043
                     /gene="Ublcp1"
                     /gene_synonym="RGD1310386"
                     /inference="alignment:Splign:2.1.0"
     exon            1044..2126
                     /gene="Ublcp1"
                     /gene_synonym="RGD1310386"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acttccggtc tccttaggtt ccgctgcggc cggctttttc gtccgctgta gctggttccg
       61 ccgcgctcca ggtgttttgt ctagcaggaa gccgctgctt catatgcttg aagaatgtca
      121 ctccccatca ttgtgaaatg gggtgggcag gaatactcgg tgaccacgct ctcagaggat
      181 gacactgtgc tggatctcaa gcagttcctc aagaccctta caggagtgct cccagagcgc
      241 cagaaattac tagggctcaa agtaaaaggc aaacctgcag aaaatgatgt taagcttgga
      301 gctctcaaac tgaaaccaaa tactaaaatc atgatgatgg gaactcgtga ggagagcttg
      361 gaagatgtct tatgtcctcc ccctgacaat gatgatgtca tcaatgattt tgacattgaa
      421 gatgaagtag ttgaagtaga aaatagggaa gaaaacctat tgaagatctc tcgcagggtc
      481 aaggagtaca aggtggaagt gctgaaccct cccagggaag ggaagaagct tctggtgctg
      541 gatgttgatt atacgctatt tgatcatagg tcttgtgcag agactggggt agagttaatg
      601 aggccatatc ttcatgaatt tctaacatct gcatatgaag attatgacat tgttatttgg
      661 tctgcaacaa atatgaagtg gattgaagct aaaatgaaag agctgggagt gagcactaat
      721 gccaactata agattacctt catgctagac agtgccgcca tgataactgt gcacacacca
      781 cggagggggc tcattgacgt gaagcctctt ggtgtcattt ggggaaagtt ttctgaattc
      841 tacagcaaaa aaaacaccat tatgtttgat gacataggaa gaaattttct aatgaaccca
      901 caaaatggac tgaagatacg gcctttcatg aaagctcatc taaatcgtga taaagacaag
      961 gaactggtga agctcactca gtacctcaag gagatagcca agcttgatga cttcctggag
     1021 ctgaatcaca agtactggga acggtatcta tctaagaagc aaggacagta gttaccagtt
     1081 acactcacag ttgaaggtcc ttgaggtcca tggacctttt tttctttgct aggcattacc
     1141 atgtttgtgc tggacactga agcagatgcc aggttgccta gctgtggtct tccaatgctt
     1201 tgtaaattta attttgtatt tttttgaaga tcataacaaa gtgctaaaaa acaaaacaaa
     1261 aagttctctt ccctctgtgt taatttactc ctgaagaaat gtttttgggc attaattatt
     1321 gaggtgtttc ccaaaccctc taaacatgca aaaaagaaag gaaaatgaaa agtggagaaa
     1381 atatacctac cagtgtcatc ctgtgacttt ggaaatgagt tttgtcttat gcttttatgc
     1441 ttttgtctcc ttgtataatc cgctgcctga gtctgagacc aaatctatct tcaactagct
     1501 agtgttctcc cccttaaaac caaaagcaaa accaaaaatc ccagaccagc ttttaagtaa
     1561 tgacctggtt tgttatgctg aaaactccca agagttgtct ccttgtcaga gtttctctac
     1621 tgcagtcttc caggaagatc ttgaagctgg agttgtcagt gttctttaag aatgaaggac
     1681 atctgtgtga tatggctgtg ccctagatga cagggtaaca agcagactga agtaacactg
     1741 caggacaaga atatgtttct ttttggtggc taagtagaaa aagcctttct gcctacactg
     1801 tagtcctgag cacagcttac cacagtagta aaaaggcacc gtcaccaact ccactctcag
     1861 aagcatggat agcatttctg cctactccac ctagtgtcat tgtaactgct aacaccaaac
     1921 atctagccat gagagtaaaa agatctgtta cttgcaatgc ttaagccttg tgcaaatatg
     1981 taatgtgact attgttttat gttgacagta ttgctttata cagttcttgc attgaaggga
     2041 attgctcctt ttaaatgaac atggtgtaca ttgttcttat gggactattt cagtggtgta
     2101 aataataaat atcttttctt aaaaca
//
