LOCUS       NM_001048243             543 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus ubiquitin-like 5 (Ubl5), transcript variant 1,
            mRNA.
ACCESSION   NM_001048243 XM_001077057 XM_576366
VERSION     NM_001048243.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 543)
  AUTHORS   Hasson,S.A., Kane,L.A., Yamano,K., Huang,C.H., Sliter,D.A.,
            Buehler,E., Wang,C., Heman-Ackah,S.M., Hessa,T., Guha,R.,
            Martin,S.E. and Youle,R.J.
  TITLE     High-content genome-wide RNAi screens identify regulators of parkin
            upstream of mitophagy
  JOURNAL   Nature 504 (7479), 291-295 (2013)
   PUBMED   24270810
REFERENCE   2  (bases 1 to 543)
  AUTHORS   Ziolkowska,A., Rucinski,M., Tyczewska,M., Belloni,A.S., Nowak,M.,
            Nussdorfer,G.G. and Malendowicz,L.K.
  TITLE     Down-regulation of the beacon gene expression in the regenerating
            rat adrenal cortex
  JOURNAL   Peptides 27 (12), 3216-3219 (2006)
   PUBMED   17097194
  REMARK    GeneRIF: a hypothalamic peptide involved in the regulation of food
            intake which might act as an endogenous inhibitor of adrenocortical
            growth in the rat.
REFERENCE   3  (bases 1 to 543)
  AUTHORS   Wang,F., Tian,D.R., Tian,N., Chen,H., Shi,Y.S., Chang,J.K.,
            Yang,J., Yuan,L. and Han,J.S.
  TITLE     Distribution of beacon immunoreactivity in the rat brain
  JOURNAL   Peptides 27 (1), 165-171 (2006)
   PUBMED   16157417
  REMARK    GeneRIF: The topographical distribution of beacon immunoreactivity
            in rat brain indicates its possible function as a
            neutrotransmitter, a neuromodulator, or a neuroendocrine regulator,
            depending upon its localization.
REFERENCE   4  (bases 1 to 543)
  AUTHORS   Rucinski,M., Andreis,P.G., Ziolkowska,A., Nussdorfer,G.G. and
            Malendowicz,L.K.
  TITLE     Differential expression and function of beacon in the rat adrenal
            cortex and medulla
  JOURNAL   Int J Mol Med 16 (1), 35-40 (2005)
   PUBMED   15942675
  REMARK    GeneRIF: The hypothesis is advanced that beacon is to be considered
            an autocrine-paracrine negative regulator of mineralo- and
            glucocorticoid synthesis in the rat adrenal gland.
REFERENCE   5  (bases 1 to 543)
  AUTHORS   Friedman,J.S., Koop,B.F., Raymond,V. and Walter,M.A.
  TITLE     Isolation of a ubiquitin-like (UBL5) gene from a screen identifying
            highly expressed and conserved iris genes
  JOURNAL   Genomics 71 (2), 252-255 (2001)
   PUBMED   11161819
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Mar 19, 2021 this sequence version replaced NM_001048243.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CO384247.1, CN543492.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-174               JAXUCZ010000008.1  27459665-27459838
            175-241             JAXUCZ010000008.1  27460054-27460120
            242-325             JAXUCZ010000008.1  27460267-27460350
            326-363             JAXUCZ010000008.1  27460491-27460528
            364-543             JAXUCZ010000008.1  27461279-27461458
FEATURES             Location/Qualifiers
     source          1..543
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q13"
     gene            1..543
                     /gene="Ubl5"
                     /gene_synonym="beacon"
                     /note="ubiquitin-like 5"
                     /db_xref="GeneID:500954"
                     /db_xref="RGD:1564644"
     exon            1..174
                     /gene="Ubl5"
                     /gene_synonym="beacon"
                     /inference="alignment:Splign:2.1.0"
     exon            175..241
                     /gene="Ubl5"
                     /gene_synonym="beacon"
                     /inference="alignment:Splign:2.1.0"
     CDS             186..407
                     /gene="Ubl5"
                     /gene_synonym="beacon"
                     /note="ubiquitin-like 5 protein"
                     /codon_start=1
                     /product="ubiquitin-like protein 5"
                     /protein_id="NP_001041708.2"
                     /db_xref="GeneID:500954"
                     /db_xref="RGD:1564644"
                     /translation="MIEVVCNDRLGKKVRVKCNTDDTIGDLKKLIAAQTGTRWNKIVL
                     KKWYTIFKDHVSLGDYEIHDGMNLELYYQ"
     exon            242..325
                     /gene="Ubl5"
                     /gene_synonym="beacon"
                     /inference="alignment:Splign:2.1.0"
     exon            326..363
                     /gene="Ubl5"
                     /gene_synonym="beacon"
                     /inference="alignment:Splign:2.1.0"
     exon            364..543
                     /gene="Ubl5"
                     /gene_synonym="beacon"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acttccgctt cctgtttcca gccctaaatc cggtcaggat tcagcgttcg agctacaagt
       61 tgtgtcgtcg ctaggttcga ggacattgga ggtgagaagg ctaaacggag aggccggaga
      121 tcgcgggaag ctgccaagac ttgggagcct aggggttgcg ggaggcaaag ccggctccag
      181 ccacaatgat tgaggtggtt tgcaacgacc gtctaggaaa gaaagtccgc gttaagtgca
      241 acaccgatga caccatcggc gacctgaaga aactgatagc ggctcaaact ggcacccgct
      301 ggaataagat cgttcttaaa aagtggtaca cgatttttaa agaccacgtg tctctgggag
      361 actatgagat ccacgacggg atgaacctgg agctttatta ccagtagagg ggactcctcc
      421 ctcctcccct cgtctccctg ctctgccctg ccttcccctc cctccctcat ttgacactgg
      481 tatagatggt catttttaac agttcacatg aataaaattt tgctgctgct ttgctgctgt
      541 cat
//
