LOCUS       NM_001399156            1883 bp    mRNA    linear   ROD 05-AUG-2024
DEFINITION  Rattus norvegicus ubiquitin-conjugating enzyme E2F (putative)
            (Ube2f), transcript variant 3, mRNA.
ACCESSION   NM_001399156 XM_006245427
VERSION     NM_001399156.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1883)
  AUTHORS   Huang,D.T., Ayrault,O., Hunt,H.W., Taherbhoy,A.M., Duda,D.M.,
            Scott,D.C., Borg,L.A., Neale,G., Murray,P.J., Roussel,M.F. and
            Schulman,B.A.
  TITLE     E2-RING expansion of the NEDD8 cascade confers specificity to
            cullin modification
  JOURNAL   Mol Cell 33 (4), 483-495 (2009)
   PUBMED   19250909
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Jan 4, 2022 this sequence version replaced XM_006245427.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360176.831422.1, CO399847.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-118               JAXUCZ010000009.1  99293515-99293632
            119-296             JAXUCZ010000009.1  99297478-99297655
            297-326             JAXUCZ010000009.1  99306216-99306245
            327-392             JAXUCZ010000009.1  99309575-99309640
            393-460             JAXUCZ010000009.1  99317991-99318058
            461-531             JAXUCZ010000009.1  99319251-99319321
            532-589             JAXUCZ010000009.1  99321149-99321206
            590-622             JAXUCZ010000009.1  99322343-99322375
            623-685             JAXUCZ010000009.1  99324911-99324973
            686-1883            JAXUCZ010000009.1  99327488-99328685
FEATURES             Location/Qualifiers
     source          1..1883
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q36"
     gene            1..1883
                     /gene="Ube2f"
                     /gene_synonym="RGD1307608"
                     /note="ubiquitin-conjugating enzyme E2F (putative)"
                     /db_xref="GeneID:363284"
                     /db_xref="RGD:1307608"
     exon            1..118
                     /gene="Ube2f"
                     /gene_synonym="RGD1307608"
                     /inference="alignment:Splign:2.1.0"
     exon            119..296
                     /gene="Ube2f"
                     /gene_synonym="RGD1307608"
                     /inference="alignment:Splign:2.1.0"
     CDS             179..736
                     /gene="Ube2f"
                     /gene_synonym="RGD1307608"
                     /EC_number="2.3.2.34"
                     /note="isoform 1 is encoded by transcript variant 3;
                     NEDD8-conjugating enzyme UBE2F; NEDD8 protein ligase
                     UBE2F; NEDD8 carrier protein UBE2F; ubiquitin-conjugating
                     enzyme E2 F; RING-type E3 NEDD8 transferase UBE2F"
                     /codon_start=1
                     /product="NEDD8-conjugating enzyme UBE2F isoform 1"
                     /protein_id="NP_001386085.1"
                     /db_xref="GeneID:363284"
                     /db_xref="RGD:1307608"
                     /translation="MLTLASKLKRDDGLKGSRASASTSDSTRRVSVRDKLLVKEVAEL
                     EANLPCTCKVHFPDPNKLHCFQLTVSPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLT
                     KIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIE
                     AAEHHLRDKEDFRDKVDEYIKRYAR"
     exon            297..326
                     /gene="Ube2f"
                     /gene_synonym="RGD1307608"
                     /inference="alignment:Splign:2.1.0"
     exon            327..392
                     /gene="Ube2f"
                     /gene_synonym="RGD1307608"
                     /inference="alignment:Splign:2.1.0"
     exon            393..460
                     /gene="Ube2f"
                     /gene_synonym="RGD1307608"
                     /inference="alignment:Splign:2.1.0"
     exon            461..531
                     /gene="Ube2f"
                     /gene_synonym="RGD1307608"
                     /inference="alignment:Splign:2.1.0"
     exon            532..589
                     /gene="Ube2f"
                     /gene_synonym="RGD1307608"
                     /inference="alignment:Splign:2.1.0"
     exon            590..622
                     /gene="Ube2f"
                     /gene_synonym="RGD1307608"
                     /inference="alignment:Splign:2.1.0"
     exon            623..685
                     /gene="Ube2f"
                     /gene_synonym="RGD1307608"
                     /inference="alignment:Splign:2.1.0"
     exon            686..1883
                     /gene="Ube2f"
                     /gene_synonym="RGD1307608"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acttccggtc ccgccgccgg gagccggtgc ggctgtgaag gccagcgcga ctcggtgccg
       61 ctgctggccg ggcatgattt tgggtgccgg cttgcctcgc ctgactcgcg gtgctcagtg
      121 tctggagaca tggccctaac cctccccttg cctgtcttcc agaagaaagg tggcagtaat
      181 gctaactctg gcaagcaagt tgaagcggga tgatggtctc aaaggatccc gggcctcagc
      241 ctccacatcc gactccactc ggagggtttc tgtgagagac aagttgcttg ttaaagaggt
      301 tgcagaactt gaagctaatt taccttgtac ctgtaaagta cattttcctg atccaaacaa
      361 gcttcactgc tttcagctga ctgtaagccc agatgagggt tactaccagg gtggaaaatt
      421 tcagtttgaa actgaagttc ctgatgccta caacatggtg cctcccaagg tgaaatgctt
      481 gactaaaatc tggcacccca acatcacaga aacaggggaa atatgcctaa gtttactaag
      541 agaacattca attgatggca ctggctgggc tcccactaga acgttaaagg atgttgtttg
      601 gggattaaac tctttattta ctgatctttt gaattttgat gatccactga acattgaagc
      661 tgcagaacat catttgcggg acaaggaaga ttttcgggac aaagtggatg aatacatcaa
      721 acgctatgcc agatgataga aggagagatg gcaggtctga ggactttgtc acagttgtct
      781 ctgatgtgaa acagctcgag gtatccctct tccccatcct catactccct gtcagcccct
      841 tgggattgtc ccagtcctgc gaccatgctg tcctgaagaa gaccctcctg actacccact
      901 gtaggtggag aacaacacaa tacagcaaga aagtgtgtct gggcctcgag agagttgtct
      961 acttccctta acatgtttac tgaaactact gtctaggctg tctggtggaa ttcctccgaa
     1021 gttgtaagga actcaccact gaggatgtag cgcttgctgc ccttccccca acaatcggta
     1081 tcctgcacaa gtgatgtaat gacatgttcc gtgtgactgg cagattggca ataagaaacc
     1141 cgctataaac tgtgattgga tgcacattct cttagcttct tccacgaatg ctgaccctac
     1201 ctagatgtga agcttcccag aatgcatagt cattcactgt agatcttact gaaatgcgta
     1261 ttttatttaa tgtaagtata ttttggaaca gatttgtaat ttgtacaatt tgatgcttta
     1321 attatttttc tattcttatt tactttgtat tcattgtata gagcaaacac agagatattg
     1381 ggtcaagaaa ctactgaaga gaaatacaaa gagaccatgc taggcacata attcagtttc
     1441 tccagatgca gcaggaatct ggctcccaga caccagctct ttcttcaggt ccacatgtgg
     1501 atgtctgaga gcctgagaac ctacacctgg atgatcaaaa ccaaaggcag ggaggcttcc
     1561 ctcacatgct acccagacac agcaggtaag ggtggcaggt gactctgcca tggccttagc
     1621 acagactgtc attgccgtcc tgcctgcaga agcagcccag tctctgaccc tgccaaaact
     1681 ccactgtgac tgtcttccaa tttgccagtg gttccaagtc ggggaatctc atagtccttt
     1741 gcaggccaag cagcagcagc agatgccata gtcggggcag tgcacttcaa ggtcagccct
     1801 ggagagagac agacgggttt attctagctt taggtatctg aaccagtgaa gtctaatgca
     1861 aaataaatgc atgtctggtt tta
//
