LOCUS       NM_001047857            1674 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ubiquitin-conjugating enzyme E2E 3 (Ube2e3),
            mRNA.
ACCESSION   NM_001047857 XM_001067181 XM_215754
VERSION     NM_001047857.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1674)
  AUTHORS   David,Y., Ziv,T., Admon,A. and Navon,A.
  TITLE     The E2 ubiquitin-conjugating enzymes direct polyubiquitination to
            preferred lysines
  JOURNAL   J Biol Chem 285 (12), 8595-8604 (2010)
   PUBMED   20061386
REFERENCE   2  (bases 1 to 1674)
  AUTHORS   Plafker,S.M. and Macara,I.G.
  TITLE     Ribosomal protein L12 uses a distinct nuclear import pathway
            mediated by importin 11
  JOURNAL   Mol Cell Biol 22 (4), 1266-1275 (2002)
   PUBMED   11809816
REFERENCE   3  (bases 1 to 1674)
  AUTHORS   Matuschewski,K., Hauser,H.P., Treier,M. and Jentsch,S.
  TITLE     Identification of a novel family of ubiquitin-conjugating enzymes
            with distinct amino-terminal extensions
  JOURNAL   J Biol Chem 271 (5), 2789-2794 (1996)
   PUBMED   8576256
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Feb 10, 2021 this sequence version replaced NM_001047857.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643294.13654.1,
                                           SRR22399489.548169.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-351               JAXUCZ010000003.1  84194246-84194596
            352-574             JAXUCZ010000003.1  84195700-84195922
            575-625             JAXUCZ010000003.1  84197706-84197756
            626-758             JAXUCZ010000003.1  84243275-84243407
            759-906             JAXUCZ010000003.1  84248139-84248286
            907-1674            JAXUCZ010000003.1  84249465-84250232
FEATURES             Location/Qualifiers
     source          1..1674
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q24"
     gene            1..1674
                     /gene="Ube2e3"
                     /note="ubiquitin-conjugating enzyme E2E 3"
                     /db_xref="GeneID:295686"
                     /db_xref="RGD:1308894"
     exon            1..351
                     /gene="Ube2e3"
                     /inference="alignment:Splign:2.1.0"
     exon            352..574
                     /gene="Ube2e3"
                     /inference="alignment:Splign:2.1.0"
     CDS             381..1004
                     /gene="Ube2e3"
                     /EC_number="6.3.2.19"
                     /codon_start=1
                     /product="ubiquitin-conjugating enzyme E2 E3"
                     /protein_id="NP_001041322.2"
                     /db_xref="GeneID:295686"
                     /db_xref="RGD:1308894"
                     /translation="MSSDRQRSDDESPSTSSGSSDADQRDPAAPEPEEQEERKPSATQ
                     QKKNTKLSSKTTAKLSTSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPG
                     SVYEGGVFFLDITFSSDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTIS
                     KVLLSICSLLTDCNPADPLVGSIATQYLTNRAEHDRIARQWTKRYAT"
     exon            575..625
                     /gene="Ube2e3"
                     /inference="alignment:Splign:2.1.0"
     exon            626..758
                     /gene="Ube2e3"
                     /inference="alignment:Splign:2.1.0"
     exon            759..906
                     /gene="Ube2e3"
                     /inference="alignment:Splign:2.1.0"
     exon            907..1674
                     /gene="Ube2e3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaacttgct gactgcgcga ccgggaggag ccgagccgag ccgagcgggg cggcgggagg
       61 ctgagcgcgc ggggggctcc cgcgtccctg cgcctcggcc ggcggagcgc ccaccccacc
      121 gtggctcccg gagcgcgggg cggcgccacc ctccggccgc agcgcggcac tgcacggccg
      181 cctgcgactt tcgatgttcc acactcccgg gccggagcct cggcggcggc tttttttccc
      241 gcccccccgg tccccccccc aggctgcctc catttcctca aggaaggttc ctcggcgctc
      301 tccctccccc acagcgtagc ggcgcacgag cgggccgggc gggcggccga gaagtttttc
      361 ccagagataa cttcaccaag atgtccagtg ataggcaaag gtcggatgat gagagcccta
      421 gcaccagcag tggtagttca gatgcagacc agcgagaccc tgccgctcca gagcctgagg
      481 aacaggaaga aagaaaacct tctgccaccc agcagaagaa aaacaccaaa ctctctagca
      541 aaacgactgc taagttatcc actagtgcta aaagaattca gaaggagcta gctgagatca
      601 cccttgatcc tcctcctaac tgcagtgctg ggcctaaagg agataacatt tatgaatgga
      661 ggtcaactat acttggtcca ccaggttctg tgtatgaagg tggtgttttt tttctggata
      721 tcacattttc ttcagattat ccatttaagc caccaaaggt taccttccgc accagaatct
      781 accactgcaa catcaacagt cagggagtca tctgcctgga tattctgaaa gacaactgga
      841 gtcccgcttt gactatttca aaggttttgc tctctatttg ttcccttttg acagattgca
      901 accctgcgga ccctctggtt ggaagcatag ccactcagta tttgaccaac agagcagaac
      961 acgacaggat agccagacag tggaccaaga gatacgcaac ataattcaca taatttgtat
     1021 gcggtgtgaa ggagcagaag gcctcttccc actgtgctgc ggatctttat agcctttaca
     1081 atacggactt ctgtgtatat gttatactga ctctactctt gcctttatct ctggagactg
     1141 ggagaccccc aaaaggtaaa tgctaccaag agtagaactt cgtagctgta gattagttac
     1201 gtttaaaatg cctacttgca agtcttgctt ctttgggata tcaaaatgta ttttgtgatg
     1261 tactaaggat actggtcctg aagtctacca aatattatag tgcattttag cctaattcat
     1321 tatctgtatg aagttataaa agtagctgta gatgactagg aattatgtca tttgtattaa
     1381 gcccagatct atttctgagt atgtggttca tgctgttgtg aaaatgtttt acctttgtca
     1441 gtttgtaatg aaaggatttc cttctaccct ttgtagctca gagagcaccg atgtatcatc
     1501 tcaaacacaa taaacatgct cctgaaggca gagtttcttg tcataatgtt gaaagtcttg
     1561 tcagaaggtg tgtctgagat gattgttgat gaaataagga tgtggctatg aagattgatt
     1621 attaaggact agtacaaatg aatgaattat taaatcgaaa acatttaaaa atct
//
