LOCUS       NM_001401235            2925 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus ubiquitin associated and SH3 domain containing, A
            (Ubash3a), mRNA.
ACCESSION   NM_001401235 XM_017601654
VERSION     NM_001401235.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2925)
  AUTHORS   Mordes,J.P., Cort,L., Liu,Z., Eberwine,R., Blankenhorn,E.P. and
            Pierce,B.G.
  TITLE     T Cell Receptor Genotype and Ubash3a Determine Susceptibility to
            Rat Autoimmune Diabetes
  JOURNAL   Genes (Basel) 12 (6), 852 (2021)
   PUBMED   34205929
  REMARK    GeneRIF: T Cell Receptor Genotype and Ubash3a Determine
            Susceptibility to Rat Autoimmune Diabetes.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2925)
  AUTHORS   Reppschlager,K., Gosselin,J., Dangelmaier,C.A., Thomas,D.H.,
            Carpino,N., McKenzie,S.E., Kunapuli,S.P. and Tsygankov,A.Y.
  TITLE     TULA-2 Protein Phosphatase Suppresses Activation of Syk through the
            GPVI Platelet Receptor for Collagen by Dephosphorylating Tyr(P)346,
            a Regulatory Site of Syk
  JOURNAL   J Biol Chem 291 (43), 22427-22441 (2016)
   PUBMED   27609517
  REMARK    Erratum:[J Biol Chem. 2017 Mar 10;292(10 ):4360. PMID: 28283589]
REFERENCE   3  (bases 1 to 2925)
  AUTHORS   Kang,D., Oh,S., Ahn,S.M., Lee,B.H. and Moon,M.H.
  TITLE     Proteomic analysis of exosomes from human neural stem cells by flow
            field-flow fractionation and nanoflow liquid chromatography-tandem
            mass spectrometry
  JOURNAL   J Proteome Res 7 (8), 3475-3480 (2008)
   PUBMED   18570454
REFERENCE   4  (bases 1 to 2925)
  AUTHORS   Hu,Y.H., Warnatz,H.J., Vanhecke,D., Wagner,F., Fiebitz,A.,
            Thamm,S., Kahlem,P., Lehrach,H., Yaspo,M.L. and Janitz,M.
  TITLE     Cell array-based intracellular localization screening reveals novel
            functional features of human chromosome 21 proteins
  JOURNAL   BMC Genomics 7, 155 (2006)
   PUBMED   16780588
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2925)
  AUTHORS   Carpino,N., Turner,S., Mekala,D., Takahashi,Y., Zang,H.,
            Geiger,T.L., Doherty,P. and Ihle,J.N.
  TITLE     Regulation of ZAP-70 activation and TCR signaling by two related
            proteins, Sts-1 and Sts-2
  JOURNAL   Immunity 20 (1), 37-46 (2004)
   PUBMED   14738763
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On Feb 4, 2022 this sequence version replaced XM_017601654.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643284.20848.1,
                                           SRR26643292.63775.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-168               JAXUCZ010000020.1  9293690-9293857
            169-222             JAXUCZ010000020.1  9295565-9295618
            223-409             JAXUCZ010000020.1  9300154-9300340
            410-608             JAXUCZ010000020.1  9301621-9301819
            609-778             JAXUCZ010000020.1  9304300-9304469
            779-987             JAXUCZ010000020.1  9306122-9306330
            988-1114            JAXUCZ010000020.1  9315324-9315450
            1115-1214           JAXUCZ010000020.1  9318735-9318834
            1215-1337           JAXUCZ010000020.1  9319586-9319708
            1338-1430           JAXUCZ010000020.1  9323183-9323275
            1431-1575           JAXUCZ010000020.1  9324966-9325110
            1576-1682           JAXUCZ010000020.1  9325824-9325930
            1683-1792           JAXUCZ010000020.1  9327176-9327285
            1793-2925           JAXUCZ010000020.1  9329359-9330491
FEATURES             Location/Qualifiers
     source          1..2925
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..2925
                     /gene="Ubash3a"
                     /note="ubiquitin associated and SH3 domain containing, A"
                     /db_xref="GeneID:309666"
                     /db_xref="RGD:1310305"
     exon            1..168
                     /gene="Ubash3a"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..1930
                     /gene="Ubash3a"
                     /codon_start=1
                     /product="ubiquitin-associated and SH3 domain-containing
                     protein A"
                     /protein_id="NP_001388164.1"
                     /db_xref="GeneID:309666"
                     /db_xref="RGD:1310305"
                     /translation="MAAGETQLYAKVSNKLKGRSTSSLLDPLLALGFPTHTALKALAA
                     TGMKTAEEAADWLHGHCSDPSLDDPIPQEYALFLCPTGPLLEKLQEFWRESRRQCAKN
                     KAHEVFPHVTLCDFFTCEDQKVECLYEALRRAGDRILGSFPALVPLVLHSSISYLGFF
                     INDSPADVIRDFAMAFATEASALADCTIKPCTKQLHLTLAHKFYPHHQRTLEQLARAI
                     QPSHTCQWTAALYSRDMRFVHYQTLKALFQYKPQNADELMLSPGDYIFVDPTQQEEAS
                     EGWAIGISHRTGCRGFLPENYTERANEADTWVKHRTYTFSLAMDLNSRKEFEASSRRN
                     GDSHTPSVSRSISDIQALQATIARRGVLVIRHGERVDQVFGKSWLHQCTTTDGKYYRP
                     DLNFPRSLPRRSNGIKDFENDPPLSSCGIFQARLAGEALLDSGVRVTAVFASPALRCV
                     QTAKHILEELKLERRLKIKVEPGIFEWMKWEAGKATLTFLTLEELKEADFNVDLDYRP
                     AFPCCSLLPAESYDQYVERCAVSMGQIINTCPQDMGITLIVSHSSALDSCTRPLLGLP
                     PRECGDFAQLVRKIPSLGMCFCEENKEDGKWDLVNPPVKTLTHGANSVFNWRNWISSN
                     "
     exon            169..222
                     /gene="Ubash3a"
                     /inference="alignment:Splign:2.1.0"
     exon            223..409
                     /gene="Ubash3a"
                     /inference="alignment:Splign:2.1.0"
     exon            410..608
                     /gene="Ubash3a"
                     /inference="alignment:Splign:2.1.0"
     exon            609..778
                     /gene="Ubash3a"
                     /inference="alignment:Splign:2.1.0"
     exon            779..987
                     /gene="Ubash3a"
                     /inference="alignment:Splign:2.1.0"
     exon            988..1114
                     /gene="Ubash3a"
                     /inference="alignment:Splign:2.1.0"
     exon            1115..1214
                     /gene="Ubash3a"
                     /inference="alignment:Splign:2.1.0"
     exon            1215..1337
                     /gene="Ubash3a"
                     /inference="alignment:Splign:2.1.0"
     exon            1338..1430
                     /gene="Ubash3a"
                     /inference="alignment:Splign:2.1.0"
     exon            1431..1575
                     /gene="Ubash3a"
                     /inference="alignment:Splign:2.1.0"
     exon            1576..1682
                     /gene="Ubash3a"
                     /inference="alignment:Splign:2.1.0"
     exon            1683..1792
                     /gene="Ubash3a"
                     /inference="alignment:Splign:2.1.0"
     exon            1793..2925
                     /gene="Ubash3a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actttatcta atccttgcag tgagcagacg cctcgtgtac ggcaagcagg aaggcatggc
       61 tgccggggag acacagctct atgccaaggt ctccaacaag ctcaagggcc gcagcacctc
      121 ctcactcctg gaccccctcc tggctttggg cttccccaca cataccgcgc tcaaagcact
      181 ggcggccaca gggatgaaga cagcagagga ggccgcagac tggctgcatg gccactgcag
      241 tgacccttct ctggatgacc ccatccctca ggagtatgct ctcttcctct gccccacggg
      301 gcccttgctg gaaaaactcc aagagttctg gagagagagc agacgccaat gtgcaaagaa
      361 caaagctcat gaagtcttcc ctcatgtgac actctgtgac tttttcacgt gtgaagacca
      421 gaaggtagag tgtttgtatg aggctctgag gcgtgcaggg gacaggatcc tggggtcctt
      481 ccctgccctg gttcctctcg ttctccattc ttcgatcagc tacctcggct tcttcatcaa
      541 cgacagccca gctgacgtca tccgggactt tgccatggcg ttcgccacag aggcatcagc
      601 cctggcagac tgtaccatca agccctgcac caagcagcta cacctgacct tggcccataa
      661 gttctaccct caccaccaaa ggaccctgga gcagctggcc agagccatcc agcccagcca
      721 cacctgccaa tggacagctg ccctgtactc ccgagacatg cgttttgtgc actaccagac
      781 cctgaaggcg ctgttccagt acaaacccca gaatgcagac gaactaatgc tcagtcctgg
      841 tgattacatc ttcgtggacc ccactcagca agaagaggcc agcgagggct gggccattgg
      901 gatctcacat cggactggct gccggggctt cttgccagag aactacacgg agcgagccaa
      961 tgaggccgac acctgggtta agcacaggac atacacgttc agtctcgcca tggacctgaa
     1021 ctctaggaag gagtttgaag ccagtagcag gagaaatggg gactcacaca ctccgtcagt
     1081 gtcaaggagc attagcgaca tacaagcttt gcaggctacc atcgcgagga gaggtgttct
     1141 ggtcatacgc catggtgaga gggtggacca ggtctttggg aagtcttggc tacaccagtg
     1201 cactaccact gatggaaaat actacaggcc agacctgaac ttcccccgca gcctccccag
     1261 gaggagcaac ggcatcaaag actttgaaaa cgatccgccg ttatcttcct gtggaatttt
     1321 ccaggccaga cttgctggag aagccctgct ggacagtggc gtcagagtca ccgcggtctt
     1381 cgcgtctcca gccctgcgct gcgtgcagac agccaagcac atcctggaag agctcaaact
     1441 ggagaggagg ctgaagataa aagttgagcc cggaatcttc gagtggatga agtgggaagc
     1501 cggcaaggcc actctgacct tcttgacctt ggaggagctg aaagaagcag acttcaatgt
     1561 tgacctcgac tataggccag cattcccctg ctgctccctc ttgccagccg agagctatga
     1621 ccagtacgtg gagaggtgtg ccgtgagcat ggggcagatc atcaacacat gcccacagga
     1681 catgggcatc accctcattg tgagccatag ctcagcgctc gactcctgca cgaggccact
     1741 ccttgggctc ccacccagag aatgtgggga ttttgcccaa ctggtaagaa agattccgtc
     1801 tctggggatg tgcttctgcg aagaaaacaa agaggacgga aagtgggacc tggtgaatcc
     1861 gccggtaaag acgctgacac acggggccaa ctcggtcttt aactggagaa actggatctc
     1921 aagcaactaa gtcagccaag ctttgcagga agaggtgact gccccatgcc aaggcatgag
     1981 gggctctgat tatgatcaca aaggcatcct agcccctcgg ctggtgtgat tgggagaaag
     2041 aacaaaacac acttgatact cagggggaat agctacggct catccatgcc agctgtggat
     2101 ctactgtcct gctagccact gcagaggcca gagtagaggt ttagattaag aaaccacatt
     2161 gtaacatgtg ggctgcgtag gagagaacag aggaactgcc tcacttccag gaactaacga
     2221 ctctccacac ttgaagaggc cacctgtcta ttatgtatgt tcttaggagg cctccttctt
     2281 gctatagcaa tcactctata tccagggcca cagcagctga ataaggaaca gtggtcaata
     2341 aaagaaatgg ccagcctacc agatcaatac caggacagca gccggtacta gcacttgact
     2401 aggggttctg tgctgttgcc tggacacaga gctggaggca gagtgatgct caaaagcggt
     2461 gcaaaattcc tactgcgcat agactaagtg tttggtggcg ttcctctgca gattctagag
     2521 gactcttccc cagtcatttc cagaatccag aggcctctct ccttcctggc atcatattta
     2581 ttatattata ttcctggcgt cttttatatt atgattctat tcaagtcaat cagtttgggg
     2641 aagtcctaag gcacggtcac atggcacctg ccttgagcct cctgcctcag tctcacaaag
     2701 acgctataac gaattgtgct ccgtaatcta gaatcttttc ccatcttaag atccttgaca
     2761 aaccgagccg gcaaaatccc ttagccacag gggtcacctg ttcatggtcc cagaagttag
     2821 gaggtgtctt tgaaggtcac cctccaccct acctcagcct ctgttcttcc aaacacatca
     2881 cggctcttga taagggtcta gacataaaga tctgagtctc ctaca
//
