LOCUS       NM_031687                504 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ubiquitin A-52 residue ribosomal protein fusion
            product 1 (Uba52), mRNA.
ACCESSION   NM_031687
VERSION     NM_031687.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 504)
  AUTHORS   Tiwari,S., Singh,A., Gupta,P., K,A. and Singh,S.
  TITLE     UBA52 Attunes VDAC1-Mediated Mitochondrial Dysfunction and
            Dopaminergic Neuronal Death
  JOURNAL   ACS Chem Neurosci 14 (5), 839-850 (2023)
   PUBMED   36755387
  REMARK    GeneRIF: UBA52 Attunes VDAC1-Mediated Mitochondrial Dysfunction and
            Dopaminergic Neuronal Death.
REFERENCE   2  (bases 1 to 504)
  AUTHORS   Devulapalli,R., Jones,N., Farrell,K., Musaus,M., Kugler,H.,
            McFadden,T., Orsi,S.A., Martin,K., Nelsen,J., Navabpour,S.,
            O'Donnell,M., McCoig,E. and Jarome,T.J.
  TITLE     Males and females differ in the regulation and engagement of, but
            not requirement for, protein degradation in the amygdala during
            fear memory formation
  JOURNAL   Neurobiol Learn Mem 180, 107404 (2021)
   PUBMED   33609735
  REMARK    GeneRIF: Males and females differ in the regulation and engagement
            of, but not requirement for, protein degradation in the amygdala
            during fear memory formation.
REFERENCE   3  (bases 1 to 504)
  AUTHORS   Vincenzetti,S., Nasuti,C., Fedeli,D., Ricciutelli,M.,
            Pucciarelli,S. and Gabbianelli,R.
  TITLE     Proteomic analysis for early neurodegenerative biomarker detection
            in an animal model
  JOURNAL   Biochimie 121, 79-86 (2016)
   PUBMED   26631339
REFERENCE   4  (bases 1 to 504)
  AUTHORS   Voorhees,R.M., Fernandez,I.S., Scheres,S.H. and Hegde,R.S.
  TITLE     Structure of the mammalian ribosome-Sec61 complex to 3.4 A
            resolution
  JOURNAL   Cell 157 (7), 1632-1643 (2014)
   PUBMED   24930395
REFERENCE   5  (bases 1 to 504)
  AUTHORS   Anger,A.M., Armache,J.P., Berninghausen,O., Habeck,M., Subklewe,M.,
            Wilson,D.N. and Beckmann,R.
  TITLE     Structures of the human and Drosophila 80S ribosome
  JOURNAL   Nature 497 (7447), 80-85 (2013)
   PUBMED   23636399
REFERENCE   6  (bases 1 to 504)
  AUTHORS   Redman,K.L. and Burris,G.W.
  TITLE     The cDNA for the ubiquitin-52-amino-acid fusion protein from rat
            encodes a previously unidentified 60 S ribosomal subunit protein
  JOURNAL   Biochem J 315 (Pt 1) (Pt 1), 315-321 (1996)
   PUBMED   8670124
REFERENCE   7  (bases 1 to 504)
  AUTHORS   Barnard,G.F., Mori,M., Staniunas,R.J., Begum,N.A., Bao,S.,
            Puder,M., Cobb,J., Redman,K.L., Steele,G.D. Jr. and Chen,L.B.
  TITLE     Ubiquitin fusion proteins are overexpressed in colon cancer but not
            in gastric cancer
  JOURNAL   Biochim Biophys Acta 1272 (3), 147-153 (1995)
   PUBMED   8541345
REFERENCE   8  (bases 1 to 504)
  AUTHORS   Chan,Y.L., Suzuki,K. and Wool,I.G.
  TITLE     The carboxyl extensions of two rat ubiquitin fusion proteins are
            ribosomal proteins S27a and L40
  JOURNAL   Biochem Biophys Res Commun 215 (2), 682-690 (1995)
   PUBMED   7488009
REFERENCE   9  (bases 1 to 504)
  AUTHORS   Hubbard,M.J. and Carne,A.
  TITLE     Differential feeding-related regulation of ubiquitin and
            calbindin9kDa in rat duodenum
  JOURNAL   Biochim Biophys Acta 1200 (2), 191-196 (1994)
   PUBMED   8031840
REFERENCE   10 (bases 1 to 504)
  AUTHORS   Hayashi,T., Noga,M. and Matsuda,M.
  TITLE     Nucleotide sequence and expression of the rat polyubiquitin mRNA
  JOURNAL   Biochim Biophys Acta 1218 (2), 232-234 (1994)
   PUBMED   8018730
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BP480615.1, BC061544.1 and BP492585.1.
            
            On Jan 24, 2008 this sequence version replaced NM_031687.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ217153.1, FQ222440.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-8                 BP480615.1         476-483             c
            9-500               BC061544.1         5-496
            501-504             BP492585.1         386-389
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p14"
     gene            1..504
                     /gene="Uba52"
                     /gene_synonym="Rps27a; Ubb"
                     /note="ubiquitin A-52 residue ribosomal protein fusion
                     product 1"
                     /db_xref="GeneID:64156"
                     /db_xref="RGD:68344"
     exon            1..38
                     /gene="Uba52"
                     /gene_synonym="Rps27a; Ubb"
                     /inference="alignment:Splign:2.1.0"
     exon            39..152
                     /gene="Uba52"
                     /gene_synonym="Rps27a; Ubb"
                     /inference="alignment:Splign:2.1.0"
     CDS             50..436
                     /gene="Uba52"
                     /gene_synonym="Rps27a; Ubb"
                     /note="60S ribosomal protein L40; ubiquitin-60S ribosomal
                     protein L40; CEP52"
                     /codon_start=1
                     /product="ubiquitin-ribosomal protein eL40 fusion protein"
                     /protein_id="NP_113875.1"
                     /db_xref="GeneID:64156"
                     /db_xref="RGD:68344"
                     /translation="MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLI
                     FAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLRQLAQKYNCDKMICRKCYAR
                     LHPRAVNCRKKKCGHTNNLRPKKKVK"
     exon            153..239
                     /gene="Uba52"
                     /gene_synonym="Rps27a; Ubb"
                     /inference="alignment:Splign:2.1.0"
     exon            240..504
                     /gene="Uba52"
                     /gene_synonym="Rps27a; Ubb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgctgtcct ctttctcttc aacgaggcgg ccgagcggca gacgccaaca tgcagatctt
       61 cgtgaagacc ctgacgggca agaccatcac tcttgaggtc gagcccagtg acaccatcga
      121 gaatgtcaag gccaagatcc aagacaagga aggcatcccc cctgaccagc agagactgat
      181 ctttgctggc aaacagctgg aggatggccg caccctgtcc gactacaaca tccagaaaga
      241 gtccaccttg cacctggtgc tgcgtcttcg cggtggcatc atcgagccgt cccttcgtca
      301 gcttgcccag aagtacaact gtgacaagat gatctgccgc aagtgctacg cacgcctgca
      361 cccccgtgca gtcaactgcc gcaagaagaa gtgcggccac accaacaacc tgcgccccaa
      421 gaagaaggtc aaatagagct gggccatacc tggcctgtga ccccgggacc aaataaagtc
      481 cccttccatc gactggagca gtaa
//
