LOCUS       NM_001408738            3512 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus ubiquitin-activating enzyme, Chr Y (Uba1y), mRNA.
ACCESSION   NM_001408738 XM_008773685
VERSION     NM_001408738.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3512)
  AUTHORS   Pink,C.J., Swaminathan,S.K., Dunham,I., Rogers,J., Ward,A. and
            Hurst,L.D.
  TITLE     Evidence that replication-associated mutation alone does not
            explain between-chromosome differences in substitution rates
  JOURNAL   Genome Biol Evol 1, 13-22 (2009)
   PUBMED   20333173
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3512)
  AUTHORS   Du,Y., Liu,M.L. and Jia,M.C.
  TITLE     Identification and characterization of a spermatogenesis-related
            gene Ube1 in rat testis
  JOURNAL   Sheng Li Xue Bao 60 (3), 382-390 (2008)
   PUBMED   18560730
REFERENCE   3  (bases 1 to 3512)
  AUTHORS   Rajapurohitam,V., Bedard,N. and Wing,S.S.
  TITLE     Control of ubiquitination of proteins in rat tissues by ubiquitin
            conjugating enzymes and isopeptidases
  JOURNAL   Am J Physiol Endocrinol Metab 282 (4), E739-E745 (2002)
   PUBMED   11882492
REFERENCE   4  (bases 1 to 3512)
  AUTHORS   Lopez Salon,M., Morelli,L., Castano,E.M., Soto,E.F. and
            Pasquini,J.M.
  TITLE     Defective ubiquitination of cerebral proteins in Alzheimer's
            disease
  JOURNAL   J Neurosci Res 62 (2), 302-310 (2000)
   PUBMED   11020223
REFERENCE   5  (bases 1 to 3512)
  AUTHORS   Chang,B.H. and Li,W.H.
  TITLE     Estimating the intensity of male-driven evolution in rodents by
            using X-linked and Y-linked Ube 1 genes and pseudogenes
  JOURNAL   J Mol Evol 40 (1), 70-77 (1995)
   PUBMED   7714913
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000022.1.
            
            On Jun 23, 2022 this sequence version replaced XM_008773685.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EF690356.2, SRR26643293.73189.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-173               JAXUCZ010000022.1  481352-481524
            174-290             JAXUCZ010000022.1  483578-483694
            291-346             JAXUCZ010000022.1  483817-483872
            347-515             JAXUCZ010000022.1  483957-484125
            516-650             JAXUCZ010000022.1  484212-484346
            651-757             JAXUCZ010000022.1  484906-485012
            758-848             JAXUCZ010000022.1  485227-485317
            849-981             JAXUCZ010000022.1  485999-486131
            982-1079            JAXUCZ010000022.1  487669-487766
            1080-1226           JAXUCZ010000022.1  487861-488007
            1227-1403           JAXUCZ010000022.1  488119-488295
            1404-1508           JAXUCZ010000022.1  488405-488509
            1509-1589           JAXUCZ010000022.1  488596-488676
            1590-1745           JAXUCZ010000022.1  489011-489166
            1746-1911           JAXUCZ010000022.1  490908-491073
            1912-2108           JAXUCZ010000022.1  491285-491481
            2109-2173           JAXUCZ010000022.1  493377-493441
            2174-2369           JAXUCZ010000022.1  493641-493836
            2370-2444           JAXUCZ010000022.1  494441-494515
            2445-2634           JAXUCZ010000022.1  494622-494811
            2635-2723           JAXUCZ010000022.1  495951-496039
            2724-2816           JAXUCZ010000022.1  502310-502402
            2817-3008           JAXUCZ010000022.1  502526-502717
            3009-3110           JAXUCZ010000022.1  503284-503385
            3111-3211           JAXUCZ010000022.1  503476-503576
            3212-3512           JAXUCZ010000022.1  503738-504038
FEATURES             Location/Qualifiers
     source          1..3512
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="Y"
                     /map="Yq11"
     gene            1..3512
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /note="ubiquitin-activating enzyme, Chr Y"
                     /db_xref="GeneID:25225"
                     /db_xref="RGD:3925"
     exon            1..173
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     CDS             174..3347
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /note="Ubiquitin enzyme 1 on Y; ubiquitin-activating
                     enzyme E1, Chr Y 1; ubiquitin-like modifier-activating
                     enzyme 1 Y"
                     /codon_start=1
                     /product="ubiquitin-activating enzyme, Chr Y"
                     /protein_id="NP_001395667.1"
                     /db_xref="GeneID:25225"
                     /db_xref="RGD:3925"
                     /translation="MSSSVLSKKRRVSGPDSEVDSSWPSTHSVMFGAPPGPNSGMSKN
                     KEMDIDESLYSRQLYVLGHEAMKHLQTSSVLISGLQGLGVEIAKNIILGGVKAVTLHD
                     QGTAQWADLSSQFYLHEEDIGKNRAEVSQPRLAELNSYVPVHTYTGPLVDDFLSGFQV
                     VVLTNTPLEYQLQVGEFCHSHGIKLVVADTRGLVGQLFCDFGEEMILTDANGEQPLSA
                     MVSMITKENPGIVTCLEETRHGFESGDFVSFTEVQGMSELNGIGPMEIKVLGPYSFSI
                     CDTSSFSEYTRGGIVSQVKVSQKISFKSLVASLAEPEFVITDFAKCCRPAQLHIGFQA
                     LHQFCTQHSRPPRPHNEEDAAEMVTLAQAVNAQSLPAVQQDCLDIDLIRKLAYVAAGD
                     LAPMSAFIGGLAAQEVMKACSGKFMPIRQWLYFDALECLPEHRVAFMEDKCLPRQNRY
                     DGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEITVTDMDTIE
                     KSNLNRQFLFRPWDVTKLKSETAAAAVRDINPHIRVCSHQNRVGPETEHVYDDDFFQN
                     LDGVANALDNVDARLYMDRRCVYYRKPLLESGTLGTKGNVQVVVPFLTESYSSSQDPP
                     EKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQSAENVNQYLMDPKFMERTLQLAGTQ
                     PLEVLEAIQCSLVLQRPQTWADCVTWAYQHWHTQYSHNIQQLLHNFPPDQLTSSGVLF
                     WSGPKRCPHPLTFDTNNPLHLDYVMAAANLFAQTYGLEGSQDCAAVTTLLQSLPAPKF
                     APKSGIRIHVSEQELQSTSATVDDSHLEELKTSLPTPDKMLGFKMHPIDFEKDDDSNF
                     HMDFIVAASNLRAENYDIPPADRHKSKLIAGKIIPAIATTTSAVVGLVCLELYKVVQG
                     HQQLDSFKNSFINLALPFFSFSAPLAPGYHQYYDKKWTLWDRFDVQGLQPSGEEMTLK
                     QFLDYFKTEHKLEITILSQGVSMLYSFFMPATKLQERLDQPMTEIVSRVSKRKLGQHV
                     KSLVFELCCNNESGDDIEVPYVRYIIG"
     exon            174..290
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            291..346
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            347..515
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            516..650
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            651..757
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            758..848
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            849..981
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            982..1079
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..1226
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1403
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            1404..1508
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            1509..1589
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            1590..1745
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            1746..1911
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            1912..2108
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            2109..2173
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            2174..2369
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            2370..2444
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            2445..2634
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            2635..2723
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            2724..2816
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            2817..3008
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            3009..3110
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            3111..3211
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            3212..3512
                     /gene="Uba1y"
                     /gene_synonym="Ube1y; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccagcgccat cttgttcctc gtgtgaggac gcggacgcgc cttttgtgga aggagtttct
       61 gaaaaaactg gtcagggacc tgaaggtgga ggctgcacca tcctgggacc acgtcttcga
      121 ggaagagaaa gtacgaagag agcgacaggg agcgcaaaca ggcaccagca ttgatgtcca
      181 gctcggtcct gtccaagaaa cgcagagtgt ctggacctga ctctgaggtg gattctagtt
      241 ggccttctac ccattctgtg atgtttggcg cacccccagg gccaaacagc ggaatgtcaa
      301 aaaacaagga aatggatata gatgaaagcc tttactcccg ccagctgtat gtactaggtc
      361 atgaggcaat gaaacatctc cagacgtcca gtgtactgat atcaggcctg cagggtctgg
      421 gtgtggaaat tgccaagaat atcatccttg gtggggtcaa ggctgtcact ctccatgacc
      481 agggcactgc ccagtgggct gatctgtctt cccagttcta cctgcatgag gaagatattg
      541 gcaaaaatcg agctgaggta tcccaaccac gccttgctga actcaacagt tatgttcctg
      601 tgcacactta cactggacct ctagttgacg acttccttag tggttttcag gtggtggttc
      661 ttaccaacac tcctttggaa tatcagctgc aggtgggtga attctgccat agccatggaa
      721 tcaagctggt agtagcagac actcggggcc tagttggaca actcttctgt gactttggag
      781 aggaaatgat tctcactgat gcaaatggag aacagccact cagtgctatg gtttcaatga
      841 tcactaagga gaatccaggg attgtcacct gcttggagga aacccggcat ggatttgaaa
      901 gtggtgactt tgtctctttc acagaagttc aaggcatgag tgaactgaat ggcattggtc
      961 ctatggagat caaagttctg ggtccctatt cctttagtat ctgtgatacc tccagcttct
     1021 ctgagtacac ccgtggaggc attgtcagtc aagtgaaagt atctcagaag atcagtttta
     1081 aatccctagt tgcctcgctg gcagagccag agtttgtgat aacagatttt gctaagtgct
     1141 gtcgccctgc tcagctccac attggcttcc aggccctgca tcagttctgt actcagcaca
     1201 gcaggcctcc tcggccccat aatgaggagg atgctgcaga aatggtgacc ttagcacagg
     1261 ctgtgaatgc tcaatctttg ccagcagtcc agcaggattg cctagatata gacctcatcc
     1321 ggaagttggc ctatgtagca gctggggatc tggcacccat gagtgctttc attggtggtt
     1381 tggctgccca ggaggtcatg aaggcttgtt ctggaaagtt tatgcctatt aggcagtggc
     1441 tgtactttga tgccctcgaa tgtctcccgg agcacagagt ggccttcatg gaagataagt
     1501 gcctgccgcg ccagaaccgt tacgatgggc aagtggcggt atttggatca gacctacaag
     1561 agaagcttgg caagcagaag tacttcctgg taggtgcagg tgccattggt tgtgagctgc
     1621 tcaagaactt tgccatgatt ggccttggct gtggagaggg tggagaaatc acagttacag
     1681 acatggacac cattgagaag tcaaacctga acagacagtt tctctttcgc ccctgggatg
     1741 tcacaaaatt aaagtctgag actgctgctg cagcagtacg tgacataaat ccacacatca
     1801 gggtgtgcag ccaccagaat cgagtaggcc ctgagacaga acacgtctat gatgatgact
     1861 tcttccaaaa cctggatggt gtggccaatg ctctagacaa tgtggatgct cgattataca
     1921 tggaccgccg ttgtgtttac tatcgtaagc ctctgctgga atccggcaca ttgggcacca
     1981 agggcaacgt gcaagtggtt gttcccttct tgacagaatc ttacagctct agccaggacc
     2041 cacctgagaa atccatcccc atctgcacac tgaagaactt ccccaatgcc attgagcata
     2101 ccctgcagtg ggctcgggat gagtttgaag gactgttcaa gcagtcagcc gaaaatgtta
     2161 accaatacct catggacccc aagttcatgg agcggacact gcagctagct ggcacccagc
     2221 ctttggaagt actggaggct atacagtgca gcctggtcct gcagaggcca cagacttggg
     2281 ccgactgtgt gacttgggcc taccagcact ggcacaccca gtattctcac aacatccagc
     2341 agttgctgca caacttccct ccagaccagc ttacaagctc tggggtactt ttttggtcag
     2401 gacctaaacg ctgtccacat ccactcacct ttgacacaaa caatccccta catctggatt
     2461 atgttatggc tgctgccaac ctgtttgctc agacatacgg actagaaggg tcccaggact
     2521 gtgctgctgt gaccacactc ctgcagtctc tgccagcccc caagtttgct cccaagtctg
     2581 gcatcaggat ccatgtttct gaacaggagc tgcagagtac cagtgccaca gtcgatgaca
     2641 gccacctaga ggaactcaag acttcactac ctactccaga caagatgctt ggattcaaga
     2701 tgcatcccat tgatttcgag aaggatgatg acagcaactt tcacatggat ttcattgtgg
     2761 cagcatccaa cctccgggca gaaaactatg acattccccc tgcagaccgg cataagagca
     2821 aactgattgc agggaagatc atcccagcta ttgcaaccac tacatcagct gtagttggcc
     2881 tcgtgtgtct ggagctgtat aaggtggttc agggtcacca acaactggat tcttttaaaa
     2941 acagttttat caacttggct ctgcctttct tcagcttctc tgcacctcta gctccagggt
     3001 atcaccagta ctatgataaa aagtggacat tgtgggatcg ttttgatgtg cagggactgc
     3061 aacctagtgg tgaagagatg accctcaagc agtttctaga ctactttaag acagagcaca
     3121 agctggaaat caccatacta tcccagggtg tgtccatgct ctattccttc tttatgccag
     3181 ccaccaaact ccaggaacgg ttggatcagc cgatgacaga gattgtgagc cgtgtgtcaa
     3241 agcggaaact gggccagcac gtgaagtccc ttgtgtttga gctgtgctgc aacaatgaga
     3301 gtggagacga cattgaagtt ccttatgtac gatacatcat cggctgatct cttactgact
     3361 ccattctttc agttctgtca gtctgtacca aaacctttct agttgtgata aaacctgatt
     3421 tcagacttcc ttgttcctaa gacctttgtt tagtgctgtt tttatttaca atgcttagaa
     3481 ctgaaattcg taataataca ttttcagcca gt
//
