LOCUS       NM_001191930            2249 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus UDP-N-acetylglucosamine pyrophosphorylase 1
            (Uap1), mRNA.
ACCESSION   NM_001191930 XM_573497
VERSION     NM_001191930.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2249)
  AUTHORS   Bouche,C., Serdy,S., Kahn,C.R. and Goldfine,A.B.
  TITLE     The cellular fate of glucose and its relevance in type 2 diabetes
  JOURNAL   Endocr Rev 25 (5), 807-830 (2004)
   PUBMED   15466941
  REMARK    Review article
REFERENCE   2  (bases 1 to 2249)
  AUTHORS   Van Rinsum,J., Van Dijk,W., Hooghwinkel,G.J. and Ferwerda,W.
  TITLE     Subcellular localization and tissue distribution of sialic acid
            precursor-forming enzymes
  JOURNAL   Biochem J 210 (1), 21-28 (1983)
   PUBMED   6303311
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from JAXUCZ010000013.1.
            
            [WARNING] On May 1, 2024 this sequence was replaced by
            NM_001191930.2.
            
            On Jul 17, 2010 this sequence version replaced XM_573497.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360172.243365.1,
                                           SRR22582416.900131.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760389,
                                           SAMEA5760400 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-164               JAXUCZ010000013.1  84910076-84910239   c
            165-487             JAXUCZ010000013.1  84902676-84902998   c
            488-692             JAXUCZ010000013.1  84895188-84895392   c
            693-868             JAXUCZ010000013.1  84892712-84892887   c
            869-1041            JAXUCZ010000013.1  84890570-84890742   c
            1042-1235           JAXUCZ010000013.1  84885203-84885396   c
            1236-1376           JAXUCZ010000013.1  84884602-84884742   c
            1377-1565           JAXUCZ010000013.1  84883545-84883733   c
            1566-1613           JAXUCZ010000013.1  84881982-84882029   c
            1614-1680           JAXUCZ010000013.1  84877095-84877161   c
            1681-2249           JAXUCZ010000013.1  84875719-84876287   c
FEATURES             Location/Qualifiers
     source          1..2249
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q24"
     gene            1..2249
                     /gene="Uap1"
                     /gene_synonym="RGD1561967"
                     /note="UDP-N-acetylglucosamine pyrophosphorylase 1"
                     /db_xref="GeneID:498272"
                     /db_xref="RGD:1561967"
     exon            1..164
                     /gene="Uap1"
                     /gene_synonym="RGD1561967"
                     /inference="alignment:Splign:2.1.0"
     exon            165..487
                     /gene="Uap1"
                     /gene_synonym="RGD1561967"
                     /inference="alignment:Splign:2.1.0"
     CDS             208..1773
                     /gene="Uap1"
                     /gene_synonym="RGD1561967"
                     /EC_number="2.7.7.23"
                     /note="UDP-N-acteylglucosamine pyrophosphorylase 1"
                     /codon_start=1
                     /product="UDP-N-acetylhexosamine pyrophosphorylase"
                     /protein_id="NP_001178859.1"
                     /db_xref="GeneID:498272"
                     /db_xref="RGD:1561967"
                     /translation="MNVNDLRQRLSAAGQQHLLQFWSELSEAQQGELYMELQAMNFEE
                     LNSFFQKAVGEFDRSSHQEKVDARMEPVPRQVLGSATRDQDQLQAWESEGLSQISQNK
                     VAVLLLAGGQGTRLGVTYPKGMYDVGLPSHKTLFQIQAERILKLQQLAEKQYGNKCTI
                     PWYIMTSGRTMESTKEFFTKHKFFGLKKENVVFFQQGMLPAMSFDGKVILEEKNKVSM
                     APDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCG
                     AKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLATAQKRSSDGRLLFNAGNIANHFFT
                     VPFLKDVVNVYEPQLQHHVAQKKIPYVDSQGHLIKPDKPNGIKMEKFVFDIFQFAKKF
                     VVYEVLREDEFSPLKNADSQNGKDNPTTARHALMSLHHCWVLNAGGHFIDENGSRLPA
                     IPRATNGKSETITADVNHNLKDANDVPIQCEISPLISYAGEGLEGYVADKDFHAPLII
                     DENGVHELVKNGI"
     exon            488..692
                     /gene="Uap1"
                     /gene_synonym="RGD1561967"
                     /inference="alignment:Splign:2.1.0"
     exon            693..868
                     /gene="Uap1"
                     /gene_synonym="RGD1561967"
                     /inference="alignment:Splign:2.1.0"
     exon            869..1041
                     /gene="Uap1"
                     /gene_synonym="RGD1561967"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1235
                     /gene="Uap1"
                     /gene_synonym="RGD1561967"
                     /inference="alignment:Splign:2.1.0"
     exon            1236..1376
                     /gene="Uap1"
                     /gene_synonym="RGD1561967"
                     /inference="alignment:Splign:2.1.0"
     exon            1377..1565
                     /gene="Uap1"
                     /gene_synonym="RGD1561967"
                     /inference="alignment:Splign:2.1.0"
     exon            1566..1613
                     /gene="Uap1"
                     /gene_synonym="RGD1561967"
                     /inference="alignment:Splign:2.1.0"
     exon            1614..1680
                     /gene="Uap1"
                     /gene_synonym="RGD1561967"
                     /inference="alignment:Splign:2.1.0"
     exon            1681..2249
                     /gene="Uap1"
                     /gene_synonym="RGD1561967"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggggtggc cggggcccgc gctcccctcg gctgctgctc gcggcccgcc ccgccgcccc
       61 ggcccctcgg atgaccgtat atattccagg cgggcgcggg acgccggcaa gtagccgagg
      121 cgaagaagcc ggagcctagt ccagccgcgg gagtgtcgag ggagctcccc ctcctctgtt
      181 tttacaaagc ctcactacca gagcaccatg aatgttaatg acctcagaca gaggttgtcc
      241 gcggctgggc agcagcacct gctgcagttc tggagtgagc tgtcagaagc ccagcaggga
      301 gaactttata tggaactcca agccatgaac tttgaagagc tgaactcatt tttccagaag
      361 gccgttggcg aatttgatcg atcttctcac caagaaaagg tggatgcacg gatggagcct
      421 gtgcccagac aggttttggg cagtgctacc agagatcaag accagctgca ggcctgggag
      481 agcgaaggac tttcccagat ttctcagaac aaagtagcag ttcttcttct agctggtggg
      541 caggggacaa gacttggagt cacgtatccc aagggcatgt atgatgtggg cttgccatcc
      601 cacaagacac ttttccagat acaagcagaa cgtattctga agctgcagca gttagctgag
      661 aaacagtatg gcaacaagtg caccatcccc tggtatataa tgaccagtgg cagaacgatg
      721 gaatcgacaa aggagttctt tacaaagcac aagttctttg gtttaaaaaa ggagaacgtg
      781 gtctttttcc agcagggaat gctgcctgct atgagctttg atgggaaagt tatcttggaa
      841 gagaaaaaca aagtctctat ggctccagat gggaatggtg gtctctaccg ggctcttgca
      901 gcccaaaaca ttgtggagga catggagcaa agaggcatct ggagtattca tgtctattgt
      961 gtggataaca tactggtgaa agtggcagac cctcggttca ttggattctg cattcagaaa
     1021 ggagcagact gtggggcaaa ggtggtagag aaaaccaacc ccacggagcc agtcggcgtg
     1081 gtttgccggg tggatggggt gtaccaggtg gtggagtaca gtgagatctc tctggccaca
     1141 gctcagaagc ggagctcaga cggacggctg ctgttcaacg cggggaacat cgccaatcac
     1201 ttcttcactg tgccgttcct gaaagatgtt gtcaatgttt acgaacctca gttgcagcac
     1261 catgtggctc agaagaagat tccatacgtg gattcccagg gccacttaat taagccagac
     1321 aagccaaatg gaataaagat ggaaaaattt gtctttgaca tcttccagtt tgcaaagaag
     1381 tttgtggtgt acgaagtatt acgggaagac gaattctccc cgctcaaaaa tgcagacagt
     1441 cagaatggga aggacaaccc gaccactgca aggcatgcct tgatgtccct tcaccattgc
     1501 tgggtcctca atgctggggg acacttcata gatgaaaatg gctcccgcct cccagccatc
     1561 ccccgtgcta caaatggaaa gtcagagacc atcacagctg atgtcaatca caacttgaag
     1621 gatgccaatg atgtgccgat ccagtgtgag atctctcccc tcatctctta cgctggagaa
     1681 ggacttgaag gctatgtggc agataaagac ttccatgcac ccttaatcat cgatgagaac
     1741 ggagttcatg agctggtgaa aaatggcata tgattcctta agggccacct aggaagccat
     1801 ggtttctgat agatcaactg tgcacctgca ggacctctcc tggaccgctg acatttggac
     1861 gttcatggag tttcatttgc ttgctggtat ctgataagca ggacagactt cccagatcca
     1921 gacgactgga tttcattttt acaagcattt tttttttttt ttggtgattc tcattgaagg
     1981 ttttatttat atttctaact gtctaagttc ttccaagcca aggctcacac ggcaaacagg
     2041 aagcttcatc agcttgcctc tagttgggac gttcagcatg acttcgcttg tgctggaagc
     2101 atttggtttt gaagttgtac atattgataa gtcatcatac atgtcagaag gtttctatgg
     2161 tactaaaatt ttgttttatt ttatcaagca ttaaagtttt ttaagaaaat aactggacag
     2221 taaaataaaa ttatcttctt gtctctgca
//
