LOCUS       NM_001107137            2617 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus tRNA-yW synthesizing protein 1 homolog (Tyw1),
            mRNA.
ACCESSION   NM_001107137 XM_001078133 XM_222117
VERSION     NM_001107137.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2617)
  AUTHORS   Gaudet P, Livstone MS, Lewis SE and Thomas PD.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 2617)
  AUTHORS   Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD,
            Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg
            B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T,
            Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin
            GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL,
            Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P,
            Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy
            SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH,
            Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW,
            Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J,
            Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M,
            Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW,
            Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J,
            Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U,
            Smailus DE, Schnerch A, Schein JE, Jones SJ and Marra MA.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473973.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_222117.4, XM_001078133.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168924.1, SRR8487231.185565.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760434 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2617
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q12"
     gene            1..2617
                     /gene="Tyw1"
                     /gene_synonym="RGD1310420; Rsafd1"
                     /note="tRNA-yW synthesizing protein 1 homolog"
                     /db_xref="GeneID:304423"
                     /db_xref="RGD:1310420"
     exon            1..137
                     /gene="Tyw1"
                     /gene_synonym="RGD1310420; Rsafd1"
                     /inference="alignment:Splign:2.1.0"
     CDS             134..2308
                     /gene="Tyw1"
                     /gene_synonym="RGD1310420; Rsafd1"
                     /note="radical S-adenosyl methionine and flavodoxin
                     domains 1; S-adenosyl-L-methionine-dependent tRNA
                     4-demethylwyosine synthase-like"
                     /codon_start=1
                     /product="tRNA wybutosine-synthesizing protein 1 homolog"
                     /protein_id="NP_001100607.1"
                     /db_xref="GeneID:304423"
                     /db_xref="RGD:1310420"
                     /translation="MGPPLDVWDFSSPLLSLWMNRFYIYMGCALGVTLWFCVQIIIKK
                     QVTRSQEKSVPGAPDSSLSPQEKHTHVSGVKIFYGSQTGTAKGFAVVLAKAVTSLDLP
                     VAIINLKEYDPDDNLIGEITSKNVCAFLVATYTDGRPTESAEWFCKWLEEAANDFRFG
                     KTYLKGLRYAVFGLGDSAYRSHFNKVSTNVDKWLWMLGAQRVLTRGEGDCNAVQSKHG
                     SIEADFTAWKTKFISRLQALQRGEKKGCGGDCKRGKCESAQHGPGEVRSHPHGELHPG
                     DAEEEEPCESSSEDEHGTKGYQSLNSVVDVEDLGNIMNPVKREKREKAQPEEKVVVHR
                     NSEKNEDSEARAMITPALREALTKQGYQLIGSHSGVKLCRWTKSMLRGRGGCYKHTFY
                     GIESHRCMEATPSLACANKCVFCWRHHTNPVGTEWRWKMDQPELILKEAIENHRNMIK
                     QFKGVPGLKAERFEEGMEVKHCALSLVGEPIMYPEINRLLKLLHQHGISTFLVTNAQF
                     PEEIRNLTPVTQLYVSVDASTKDSLKKIDRPLFKDFWQRFLDSLQALSAKQQRTVYRL
                     TLVKCWNVDELQAYAELVSLGSPDFIEVKGVTYCGESAASSLTMANVPWHEEVVRFVR
                     ELVDLLPDYEIACEHEHSNCLLIGHKKFKIGGEWWTWIDYSRFQELVLQYEESGGSKT
                     FSSKDYMARTPQWALFGARERGFDPKDTRYQRKNKTKDISGC"
     exon            138..268
                     /gene="Tyw1"
                     /gene_synonym="RGD1310420; Rsafd1"
                     /inference="alignment:Splign:2.1.0"
     exon            269..391
                     /gene="Tyw1"
                     /gene_synonym="RGD1310420; Rsafd1"
                     /inference="alignment:Splign:2.1.0"
     exon            392..493
                     /gene="Tyw1"
                     /gene_synonym="RGD1310420; Rsafd1"
                     /inference="alignment:Splign:2.1.0"
     exon            494..688
                     /gene="Tyw1"
                     /gene_synonym="RGD1310420; Rsafd1"
                     /inference="alignment:Splign:2.1.0"
     exon            689..970
                     /gene="Tyw1"
                     /gene_synonym="RGD1310420; Rsafd1"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1093
                     /gene="Tyw1"
                     /gene_synonym="RGD1310420; Rsafd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1094..1211
                     /gene="Tyw1"
                     /gene_synonym="RGD1310420; Rsafd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1212..1264
                     /gene="Tyw1"
                     /gene_synonym="RGD1310420; Rsafd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1265..1383
                     /gene="Tyw1"
                     /gene_synonym="RGD1310420; Rsafd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1384..1493
                     /gene="Tyw1"
                     /gene_synonym="RGD1310420; Rsafd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1494..1671
                     /gene="Tyw1"
                     /gene_synonym="RGD1310420; Rsafd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1672..1807
                     /gene="Tyw1"
                     /gene_synonym="RGD1310420; Rsafd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1808..1918
                     /gene="Tyw1"
                     /gene_synonym="RGD1310420; Rsafd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1919..2086
                     /gene="Tyw1"
                     /gene_synonym="RGD1310420; Rsafd1"
                     /inference="alignment:Splign:2.1.0"
     exon            2087..2617
                     /gene="Tyw1"
                     /gene_synonym="RGD1310420; Rsafd1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgtcccctgt agccaatgcg ggcgggcctg cgggcggcat ggcttcccta gccctgtaaa
       61 cccgaccttc ctgatctcag tcccgggttc tctgtgtttg ctggcgattt gtggggctcg
      121 ggctccgtgg aggatgggtc ctcctctgga tgtgtgggac ttctcgtcac ctttgctgtc
      181 cctatggatg aacaggttct acatatatat gggctgtgcc ctgggagtta cgctttggtt
      241 ctgtgtccag atcatcatca agaagcaggt cactcgttcc caggagaaga gtgtcccagg
      301 agctcctgat agctccctct cccctcagga gaagcataca cacgtgtctg gagtgaagat
      361 tttctacgga tcacagacgg gcactgccaa gggattcgca gtggttcttg ccaaagctgt
      421 cacctctctg gacctgcctg tggccattat taatctgaag gagtatgatc cagatgacaa
      481 cctgatagga gagatcacta gtaaaaacgt ctgtgccttt ctggttgcta cgtacacgga
      541 cggccgccct acggagagcg cagagtggtt ctgcaagtgg ttagaggaag cggccaatga
      601 tttccgcttt ggcaaaacgt acctgaaagg acttcgatat gcagtgtttg gcctgggaga
      661 ctctgcctac cggagccact tcaacaaggt cagcacgaac gtcgacaaat ggctctggat
      721 gcttggtgcc cagcgagtgc tgacccgagg ggagggcgac tgcaatgcag ttcagagcaa
      781 acatggcagc atcgaggccg acttcacagc ctggaagacc aagttcatct cccggctgca
      841 ggccctacag agaggggaga aaaagggctg tggtggggac tgcaagagag ggaagtgtga
      901 gtcggcgcag catggcccag gagaggtgcg gtctcaccca cacggcgaat tgcatcctgg
      961 ggatgctgag gaggaagagc cctgtgagag cagcagcgag gacgagcacg ggaccaaggg
     1021 ttatcagagc ctgaattctg tggttgatgt cgaggacctg ggcaacatca tgaaccccgt
     1081 gaagagggaa aagagagaaa aggctcaacc ggaggagaaa gttgtcgtgc acaggaactc
     1141 agagaagaat gaagacagcg aagcgagagc tatgattacg cctgctctgc gggaggccct
     1201 aactaaacaa gggtaccagt tgattggcag ccactccggt gtgaagcttt gcaggtggac
     1261 caagtccatg ctgcgggggc gaggaggttg ctacaagcac acattctacg gcatcgagag
     1321 ccatcgctgc atggaggcca ccccgagctt ggcatgtgcg aacaagtgtg tcttctgctg
     1381 gcggcaccat acgaatcctg tgggcacgga gtggcggtgg aagatggacc agccggaatt
     1441 gatcttgaag gaagccattg agaaccatcg gaacatgatt aaacagttca aaggcgtgcc
     1501 agggctcaag gccgagcgct tcgaagaggg gatggaggtc aagcactgtg cgctgtcact
     1561 cgtgggtgag ccaataatgt acccagagat caacaggctt ttgaagctgc tccaccagca
     1621 cgggatctcc actttccttg tcaccaatgc acagttccct gaggaaatca ggaacctcac
     1681 accagttact cagctctatg taagtgtgga cgccagcacc aaagacagcc tgaagaagat
     1741 cgaccgcccg ctcttcaagg atttctggca gcgattccta gacagtttgc aagccttatc
     1801 tgcaaagcaa cagcgaaccg tctacagact gacacttgtg aagtgttgga acgtggacga
     1861 gctccaggcc tacgccgagc tggtgtcttt ggggagcccc gacttcatcg aggtcaaggg
     1921 cgtgacctac tgcggtgaga gtgcagccag cagcctcacc atggccaacg tcccttggca
     1981 cgaggaagtt gtccggtttg tccgtgagct ggtggatctg cttcctgact atgaaattgc
     2041 gtgtgaacat gaacactcca actgcctcct gattggacac aagaagttta agatcggcgg
     2101 agagtggtgg acgtggatcg attacagccg cttccaggag ctcgtcctgc agtacgaaga
     2161 gagcggaggc tcaaagacgt tcagctcgaa ggattacatg gccagaaccc cacagtgggc
     2221 cctgtttggt gccagggaaa gaggctttga tcccaaggac acgagatacc agaggaagaa
     2281 caagacgaag gacatttccg gttgttgagc ttgtctgagc taaggatctt caaagacaga
     2341 aggtcctcgt tgccatcgct gcccacaggg cacagtttca cagccgtgtt ttacagtctg
     2401 acaccagcag gcagccgtgc tgcccacaca gcacccatac acagggctgg ggactccatg
     2461 cttcttacca gaactcaggc cctttaatga gtcgacttct cagacagtga gggcgacagt
     2521 cacttctgga gttttaatag ttttggattt tattttagta attttcctaa gtgctgtccc
     2581 cgagtgttcc tcggggaata aacatctctg cctcttc
//
