LOCUS       XM_006242209            2596 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus thymidine phosphorylase (Tymp),
            transcript variant X3, mRNA.
ACCESSION   XM_006242209
VERSION     XM_006242209.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051342.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006242209.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006242209.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2596
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..2596
                     /gene="Tymp"
                     /gene_synonym="Ecgf1; TP"
                     /note="thymidine phosphorylase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 24
                     ESTs, 9 long SRA reads, 3 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 9 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:315219"
                     /db_xref="RGD:1305756"
     CDS             277..2553
                     /gene="Tymp"
                     /gene_synonym="Ecgf1; TP"
                     /codon_start=1
                     /product="thymidine phosphorylase isoform X3"
                     /protein_id="XP_006242271.1"
                     /db_xref="GeneID:315219"
                     /db_xref="RGD:1305756"
                     /translation="MAAPGTPPPLAPETAGADSGGGSGEHRQLPELIRLKRNGGHLSE
                     ADIRNFVHALMDGRAQDTQIGAMLMAIRLQGMDLEETSVLTQALAESGQQLEWPKAWH
                     QQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRSLGHTGGTLDKLESIPGFSVT
                     QSPEQMLQILEEVGCCIVGQSEKLVPADGILYAARDVTATVDSVPLITASILSKKAVE
                     GLSTLVVDVKFGGAAVFPDQEKARELAKMLVRVGMGLGLQVAAALTAMDNPLGRNVGH
                     TLEVEEALLCLDGAGPPDLRDLVIRLAGGAILWLSGQAETQDQGAARVAAALDDGSAL
                     HRFQLMLSAQGVDPGLARALCSGSPTQRRQLLPHARKQEELLSPADGETGYLRHQALW
                     SASERCRWPVYCTSSEPDAAEQGSRSDREWVPNYWSTWANGCPAGHPGSACTWTAPRS
                     AVSSAALFWGLSCCQIEHPSRPLHPSLSLSSHRPPHSPKSPTHRCQSFRSMMLLALGP
                     KAWPKLSQFKPLLRISRGETLHINSRHWSGQGQGQHQGPGLRTRLLITALFGAGLGWA
                     WLAARAEKEQWRQQQRTEALRQAAVGQGDFSLLDHKGQPRCKADFRGQWVLMYFGFTH
                     CPDICPDELEKLVQVVQKLEAEPELPLVQPVFVTVDPERDDVAAMARYVQEFHPRLLG
                     LTGSTEQVAHASRNYRVYYSAGPKDEDQDYIVDHSIAIYLLNPDGLFTDYYGRSRSAE
                     QIVESVRRHIAAFHSILP"
ORIGIN      
        1 gatactcata gggaactggg cagagcgaac tctggtctag accgctgtaa cccgaccctt
       61 aaggtcctgg caacgtcaat tcgccacaag agagcaggta gggagcagct taaatggtga
      121 ttggccttac cttgacaagt gccgcctact gggacagccc tatttgtccg ctgtccctaa
      181 cggtagtccc agtctgaact gtctgcacct aactccacgc cgggctgagg gctaccaggc
      241 cggaacggag ccagatccag aaaactggct gcagcaatgg cagctccagg gacaccacct
      301 cccttggccc cagagacagc tggtgccgac tcggggggag ggagtgggga gcacaggcag
      361 ctgccagagc tgatccgcct caagcgaaat ggagggcatc tgagcgaagc agatatcaga
      421 aacttcgtgc acgcgttgat ggacggaaga gcacaggaca cacaaatcgg ggccatgctg
      481 atggccattc ggctgcaagg catggaccta gaggagacat ctgtgttgac tcaggccctc
      541 gcagagtctg ggcagcaact ggagtggccc aaggcctggc accagcagct tgtggacaaa
      601 cactccacag gaggtgtggg cgataaggtt agcctggttc tggcacctgc cctggctgca
      661 tgtggctgca aggtaccaat gatcagcgga cgcagtttgg gacacacagg gggcacgctg
      721 gataaactgg aatctattcc tgggttcagc gtcacccaga gcccagaaca gatgctgcag
      781 atacttgagg aagtcggctg ctgcattgtt ggccagagtg aaaagctagt tcctgctgat
      841 ggaatcctgt atgctgcacg agatgtgaca gctactgtgg acagtgtacc gctcattaca
      901 gcgtcaatcc tcagtaagaa agccgtggag ggactgtcca ctctggtggt agatgttaag
      961 tttggggggg ctgcagtctt cccagaccag gagaaggccc gagaactggc aaagatgttg
     1021 gttagagtgg gaatgggtct ggggctgcag gttgctgcag ccctgaccgc catggacaac
     1081 cctctgggcc gcaacgtggg tcataccctg gaagtggaag aagcgttgct ttgcctggat
     1141 ggtgcggggc cgccggatct gcgggacctg gtcattaggc tagcaggagg cgccattctt
     1201 tggcttagcg gacaggcaga aacccaagac cagggtgccg cccgagtggc cgcggcgttg
     1261 gatgatggct ctgcgctgca ccgcttccag ctgatgcttt cggcgcaggg cgtagacccc
     1321 ggcctagcta gagcattgtg ctccggaagc cccacgcaac gccggcagtt gctgcctcac
     1381 gcccgaaagc aagaagagct gctctcaccg gcagacggtg agaccggata tctccggcac
     1441 caggcattgt ggagtgcgtc cgagcgctgc cgctggcctg tgtactgcac gagctcggag
     1501 ccggacgcag ccgagcaggg cagccgatca gaccgggagt gggtgccgaa ctactggtcg
     1561 acgtgggcca atggttgtcc cgcgggacac cctggctccg cgtgcacctg gacggccccg
     1621 cgctcagcag tcagcagcgc cgcactcttc tgggggctct cgtgctgtca gatcgagcac
     1681 ccttcaaggc cccttcaccc ttcgctgagc ttgtcctccc accgaccacc ccatagccct
     1741 aaatctccaa cccatcgctg ccagagcttc aggtccatga tgctactggc tctagggccc
     1801 aaagcttggc ccaagctctc tcagttcaaa ccccttctca ggatctcaag gggtgaaact
     1861 ctgcacataa attcccggca ttggtcgggg caaggccaag gccaacacca aggccctggg
     1921 ctaaggacta gactgttgat cactgccctg tttggggctg ggctaggctg ggcctggctg
     1981 gccgctagag ctgagaagga acagtggcgc caacaacagc ggacagaggc cctgcgccag
     2041 gctgctgtgg gccagggtga cttcagccta ctggaccaca aaggccagcc tcgatgcaaa
     2101 gccgacttcc gaggccagtg ggtgctgatg tactttggtt ttactcactg ccctgatatt
     2161 tgccccgatg agctggaaaa gctggtgcag gtagtgcaga agctcgaggc agagcctgag
     2221 ctgcccctgg tgcagcctgt cttcgtcact gtggacccag aacgagatga cgtggcagcc
     2281 atggcccgat atgtgcaaga attccaccca aggctgctgg gtctgactgg ttctacagaa
     2341 caagtggccc atgctagtcg caactaccgt gtatactaca gcgctggtcc caaggacgag
     2401 gaccaggact atattgtgga ccattccatt gccatctact tgctcaaccc agatggtctc
     2461 ttcactgatt actatggtcg tagcaggtca gcagagcaga ttgtagagag tgtacgccgg
     2521 cacatagctg ccttccatag catactgccc tgaactgtgt actgcctagg ccctgtcatt
     2581 aaatggatgt acttaa
//
