LOCUS       NM_080887               1301 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus thioredoxin-like 1 (Txnl1), mRNA.
ACCESSION   NM_080887 XM_001059942
VERSION     NM_080887.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1301)
  AUTHORS   Felberbaum-Corti,M., Morel,E., Cavalli,V., Vilbois,F. and
            Gruenberg,J.
  TITLE     The redox sensor TXNL1 plays a regulatory role in fluid phase
            endocytosis
  JOURNAL   PLoS One 2 (11), e1144 (2007)
   PUBMED   17987124
  REMARK    GeneRIF: TXNL1 acts as an effector of oxidants or a redox sensor by
            converting redox changes into changes of GDI capacity to capture
            Rab5, which in turn modulates fluid phase endocytosis
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1301)
  AUTHORS   Lee,K.K., Murakawa,M., Takahashi,S., Tsubuki,S., Kawashima,S.,
            Sakamaki,K. and Yonehara,S.
  TITLE     Purification, molecular cloning, and characterization of TRP32, a
            novel thioredoxin-related mammalian protein of 32 kDa
  JOURNAL   J Biol Chem 273 (30), 19160-19166 (1998)
   PUBMED   9668102
  REMARK    Erratum:[J Biol Chem 1998 Oct 16;273(42):27755]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC098908.1.
            
            On or before Jun 25, 2006 this sequence version replaced
            XM_001059942.1, NM_080887.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC098908.1, AF140358.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06621351, SAMN12840110
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1301
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q12.1"
     gene            1..1301
                     /gene="Txnl1"
                     /gene_synonym="Txnl"
                     /note="thioredoxin-like 1"
                     /db_xref="GeneID:140922"
                     /db_xref="RGD:621717"
     exon            1..305
                     /gene="Txnl1"
                     /gene_synonym="Txnl"
                     /inference="alignment:Splign:2.1.0"
     CDS             208..1077
                     /gene="Txnl1"
                     /gene_synonym="Txnl"
                     /note="thioredoxin-related protein; thioredoxin-like
                     (32kD)"
                     /codon_start=1
                     /product="thioredoxin-like protein 1"
                     /protein_id="NP_543163.1"
                     /db_xref="GeneID:140922"
                     /db_xref="RGD:621717"
                     /translation="MVGVKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAF
                     SSMSNKYPQAVFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEK
                     IKQHLENDPGSNEDTDIPKGYMDLMPFINKAGCECLNESDEHGFDNCLRKDLSFLESD
                     CDEQLLITVAFNQPVKLYSMKFQGPDNGQGPKYVKIFINLPRSMDFEEAERSEPTQAL
                     ELTEDDIKEDGIVPLRYVKFQNVNSVTLFVQSNQGEEETTRISYFTFIGTPVQATNMN
                     DFKRVVGKKGESH"
     exon            306..402
                     /gene="Txnl1"
                     /gene_synonym="Txnl"
                     /inference="alignment:Splign:2.1.0"
     exon            403..576
                     /gene="Txnl1"
                     /gene_synonym="Txnl"
                     /inference="alignment:Splign:2.1.0"
     exon            577..699
                     /gene="Txnl1"
                     /gene_synonym="Txnl"
                     /inference="alignment:Splign:2.1.0"
     exon            700..769
                     /gene="Txnl1"
                     /gene_synonym="Txnl"
                     /inference="alignment:Splign:2.1.0"
     exon            770..942
                     /gene="Txnl1"
                     /gene_synonym="Txnl"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1047
                     /gene="Txnl1"
                     /gene_synonym="Txnl"
                     /inference="alignment:Splign:2.1.0"
     exon            1048..1280
                     /gene="Txnl1"
                     /gene_synonym="Txnl"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctcccctcc cagcccgcgt ctcctccccc tccgctcgcc tgctccctgg cgtgactcgg
       61 cactcgcagc accgggagga cacgtcgtgg tcgccgttcc cgcccaggcc ccggcctcct
      121 gcagcctctc tccggcctct ctcgggcttt cgtcttaagt tttgaggccg gaggcgtcgt
      181 ggccgtcctg ccgggctctc tgtaaggatg gtgggagtga agccggtcgg gagcgatcca
      241 gatttccagc cggagctgag tggggcgggc tccagacttg ctgtggtcaa gttcaccatg
      301 agagggtgtg gaccatgttt gaggatcgcc ccggcattca gttctatgag taataagtac
      361 ccacaggcag tcttcttgga agtagatgtg catcagtgcc agggaacagc tgccaccaac
      421 aatatatcag caacacctac atttttgttt tttcgaaaca aagtgagaat tgatcagtat
      481 caaggagcag atgctgtggg actggaagaa aaaatcaagc agcatttaga aaatgaccct
      541 ggaagcaatg aggacacaga cattcccaag ggctatatgg atttaatgcc ttttattaac
      601 aaagctggct gcgaatgtct caatgaaagt gatgagcacg gctttgacaa ctgcttacga
      661 aaagacctgt ccttcttgga gtctgactgc gacgagcagc tgcttattac tgtggcattc
      721 aatcaaccag ttaaacttta ttccatgaag tttcaaggac cagataatgg tcagggtcct
      781 aaatatgtaa aaatttttat caacctaccc cgatctatgg actttgagga ggcagaaagg
      841 agtgagccaa cccaagctct ggaactgaca gaagatgaca ttaaagaaga tggcattgtt
      901 cctcttcgtt atgttaaatt tcagaatgtg aacagtgtaa ctttgtttgt tcagtctaat
      961 caaggagaag aagaaacaac aagaatttcc tattttactt tcattggtac tcccgtccag
     1021 gcaacaaata tgaatgactt caaacgagta gttggcaaaa agggggaaag ccattagggt
     1081 acaaaagaca ctggaagact actgcagtca gatttgcagc tcctggataa ttgcttgatt
     1141 ctcttcggaa actgttaatc ttttatttgt tgccagtacc aataaatcat tgcttttgtt
     1201 cagatggtaa tactagtgtt tctattgtaa tcttgataca tgcagttgta aataaaagtc
     1261 attactttgc caagcttaaa aaaaaaaaaa aaaaaaaaaa a
//
