LOCUS       NM_001271330            2631 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus thioredoxin domain containing 5 (Txndc5), mRNA.
ACCESSION   NM_001271330 XM_002725245 XM_002728463
VERSION     NM_001271330.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2631)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   2  (bases 1 to 2631)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
REFERENCE   3  (bases 1 to 2631)
  AUTHORS   Knoblach,B., Keller,B.O., Groenendyk,J., Aldred,S., Zheng,J.,
            Lemire,B.D., Li,L. and Michalak,M.
  TITLE     ERp19 and ERp46, new members of the thioredoxin family of
            endoplasmic reticulum proteins
  JOURNAL   Mol Cell Proteomics 2 (10), 1104-1119 (2003)
   PUBMED   12930873
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FM045749.1, FM067602.1, JAXUCZ010000017.1 and FM093163.1.
            
            On or before Sep 16, 2012 this sequence version replaced
            XM_002725245.2, XM_002728463.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22582424.383515.1,
                                           SRR22582416.438579.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-538               FM045749.1         6-543
            539-860             FM067602.1         305-626
            861-988             JAXUCZ010000017.1  26517189-26517316
            989-1056            JAXUCZ010000017.1  26519956-26520023
            1057-1741           FM093163.1         15-699
            1742-2631           JAXUCZ010000017.1  26522719-26523608
FEATURES             Location/Qualifiers
     source          1..2631
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p12"
     gene            1..2631
                     /gene="Txndc5"
                     /note="thioredoxin domain containing 5"
                     /db_xref="GeneID:100362805"
                     /db_xref="RGD:2323973"
     exon            1..291
                     /gene="Txndc5"
                     /inference="alignment:Splign:2.1.0"
     CDS             71..1324
                     /gene="Txndc5"
                     /EC_number="5.3.4.1"
                     /note="thioredoxin domain containing 5 (endoplasmic
                     reticulum); thioredoxin domain-containing protein 5"
                     /codon_start=1
                     /product="thioredoxin domain-containing protein 5
                     precursor"
                     /protein_id="NP_001258259.1"
                     /db_xref="GeneID:100362805"
                     /db_xref="RGD:2323973"
                     /translation="MPPRPGRLFQPLAGLPALATLLLLLGARKGARAQEVEADSGVEQ
                     DPHAKHLYTADMFTHGIQSAAHFVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYV
                     AKVDCTANSDVCSAQGVRGYPTLKFFKPGQEAVKYQGPRDFETLENWMLQTLNEEPAT
                     PEPEAEPPRAPELKQGLYELSANNFELHVSQGNHFIKFFAPWCGHCKALAPTWEQLAL
                     GLEHSETVKIGKVDCTQHYAVCSEHQVRGYPTLLWFRDGKKVDQYKGKRDLESLRDYV
                     QSQLQGSEAAPETVEPSEAPVLAAEPPGDKGTVLALTEKSFEDTIAQGITFVKFYAPW
                     CGHCKNLAPTWEELSKKEFPGLADVTIAEVDCTAERGVCSKYSVRGYPTLLLFRGGEK
                     VGEHNGGRDLDSLHSFVLRQAKDEL"
     exon            292..441
                     /gene="Txndc5"
                     /inference="alignment:Splign:2.1.0"
     exon            442..547
                     /gene="Txndc5"
                     /inference="alignment:Splign:2.1.0"
     exon            548..644
                     /gene="Txndc5"
                     /inference="alignment:Splign:2.1.0"
     exon            645..760
                     /gene="Txndc5"
                     /inference="alignment:Splign:2.1.0"
     exon            761..847
                     /gene="Txndc5"
                     /inference="alignment:Splign:2.1.0"
     exon            848..988
                     /gene="Txndc5"
                     /inference="alignment:Splign:2.1.0"
     exon            989..1071
                     /gene="Txndc5"
                     /inference="alignment:Splign:2.1.0"
     exon            1072..1201
                     /gene="Txndc5"
                     /inference="alignment:Splign:2.1.0"
     exon            1202..2631
                     /gene="Txndc5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccggggcgg ggaggcggcg cggcgaaggg ggacccgcgg ccccggcgag agctcgccag
       61 ccccgccgcg atgcccccgc gcccaggacg cctcttccag ccgctggccg ggctaccggc
      121 tctggccacg ctcctgctgc tgctcggagc gcgtaagggt gcccgggccc aggaggtgga
      181 ggcggacagc ggggtcgagc aggacccgca cgccaagcac ctgtatacgg ccgacatgtt
      241 cacgcacggg atccagagcg ccgcgcactt cgtcatgttc ttcgcgccct ggtgtggaca
      301 ctgccagcgg ctgcagccaa cctggaatga cctgggagac aagtataaca gcatggaaga
      361 cgccaaggtc tacgtggcca aggtggactg cacggccaac tctgacgtgt gctctgccca
      421 gggagttcga ggatatccca cccttaagtt ttttaagcct ggacaagaag cagtgaagta
      481 ccagggtcct agagactttg aaacactgga aaactggatg ctgcagaccc tgaacgagga
      541 gccagctaca ccagagccag aggcagaacc acccagagct cccgagctta agcagggctt
      601 gtatgagctc tcggccaaca actttgagct gcatgtttct caaggcaacc actttatcaa
      661 gttcttcgct ccatggtgtg gtcactgcaa agctctggct ccaacttggg agcagctggc
      721 tctgggcctc gaacattctg aaactgtcaa gattggcaag gttgactgca cgcagcacta
      781 cgcggtctgc tcagagcacc aggtcagagg ctacccaact ctgctctggt ttcgagatgg
      841 caagaaggtg gatcagtaca agggaaagag ggacttggag tcgctgagag actatgtgca
      901 gtcccagctg cagggttcgg aggcggctcc ggagactgtt gagccatcag aggccccggt
      961 gctggctgct gagcctccgg gcgacaaggg cactgtgctg gcactcactg agaagagctt
     1021 tgaggacact attgcacaag gaataacctt cgtcaagttc tatgctccct ggtgtggcca
     1081 ctgcaagaat ctggctccta cctgggaaga gctctctaag aaggaattcc ctggcttggc
     1141 agacgtcacc atcgcagaag tggactgcac cgctgagcgt ggtgtttgca gcaagtactc
     1201 ggtacgaggc taccccacat tgctgctttt ccggggaggt gagaaagtgg gtgagcacaa
     1261 tggaggcaga gacctcgact ctctacacag ctttgttctg cgccaggcaa aggatgaact
     1321 ctaagaaccc tggtgaagcc gtcatccacc ctggccttat gcaccccgtg cataggagtg
     1381 acctcacatg gacatgcgta tcttcactgt ggttagtcag aacgctgaat gtattgagct
     1441 tgtgttgctt gctgtgtgcc ctttgagcca ccacacacta cggaccttaa gtttctctaa
     1501 tgacagctca cggtccctgg gcaaaccaaa ttattttcag tgactatcca tcctgtaacc
     1561 ttctctgaca gaactaaatc ggctcccttt gcaactaaaa cacagtcaag gaaaaccaaa
     1621 ttgctgagct ctcttggctc ctgagggatg tgaggaaagc gtcacacagc agcagttttt
     1681 cgaattgcct gagttctgga gaggaggcct gtggcactgc tgacttagta acatgtcggc
     1741 ccatagtgtg cagattgtaa agcaaaagtc cacgcagtgc tggagatccc ttcatagcca
     1801 ctgttgggtg ttattacttc tctagttgag agaggtaagc cataacaaat ggtacttctg
     1861 atgtgtgccc caaacactcg tgttttcaaa ggatcctctt gtctgctttg cgtagggtgg
     1921 agtggagagg tcttctgcag aaagtgaggg tgtgggatga tcacaaggtg ggtcctcacc
     1981 tgataagctt tcccaggtct aaggaccagg agactctgca gctccacact ggccttccta
     2041 gacacagctt ctgattctct tcctaagtag tcctcttagc ggcttgctct ataatctcca
     2101 ccatcaagga ggctgaccat ctttctaata atgtatgagc agtgggattc atttgacctc
     2161 aagaccaaag actgcagtcg gcaggacgtc taaggttgga tgtcacacag ctccttccgg
     2221 ttccgttcct gccgtcctgg ttatcagaca ctgctgctct taaccctgca gatgcagccc
     2281 gcgccatgcc cctgtctgtc ttgtcctcca aaccgtatgt ttgtgcccag cccttcaccc
     2341 acctccccat aagcagggtg aagtcaacac ctggcacaaa atgtgtggca aggaggctcg
     2401 aaacaagact acgtctgctt cctaagcatc aggcgcagag gcgcctgcca accattatga
     2461 acgtttgtta ttaaccatgt gtgggccata gctgtccgtg aaaagcagct ctattggcca
     2521 agctcacagt ggcgtcagct ttgcatcatg agtcttgtat taaaagaaaa ctcaaaagtg
     2581 gtacaattgg tttatacttt ctaaataaac tttttttttt aaagaaaaaa a
//
