LOCUS       XM_008760430            1478 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus twinkle mtDNA helicase (Twnk),
            transcript variant X3, mRNA.
ACCESSION   XM_008760430
VERSION     XM_008760430.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_008760430.4.
            
            On Jan 21, 2021 this sequence version replaced XM_008760430.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1478
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..1478
                     /gene="Twnk"
                     /gene_synonym="Peo1"
                     /note="twinkle mtDNA helicase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 6
                     ESTs, 1 long SRA read, 1 Protein, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     69 samples with support for all annotated introns"
                     /db_xref="GeneID:309441"
                     /db_xref="RGD:1307884"
     CDS             604..1299
                     /gene="Twnk"
                     /gene_synonym="Peo1"
                     /codon_start=1
                     /product="twinkle mtDNA helicase isoform X2"
                     /protein_id="XP_008758652.1"
                     /db_xref="GeneID:309441"
                     /db_xref="RGD:1307884"
                     /translation="MLTQFAVTRLEEQLDKYEEWADRFEDLPLYFMTFHGQQSIRSVI
                     DTMQHAVYVYDVCHVVIDNLQFMMGHEQLSTDRIAAQDYIVGAFRKFATDNSCHVTLV
                     IHPRKEDDDKELQTASIFGSAKASQEADNVLILQDRKLVTGPGKRYLQVSKNRFDGDV
                     GVFPLEFNKSSLTFSIPPKSKARLKKIKDDNGLVAKKSSSGKKGSAHQNSETCIGQDP
                     CQPDTSPSSRHKN"
ORIGIN      
        1 ggttctctac tgtgctcata ttgaagctgg agcagaatcc tggagttctc tgggccgcag
       61 cccgtggaag gtagtccgtt tgttggtgaa ggggtgccac tggccctgga tgctagggtt
      121 gtccgtgtgg aagggcttgc ggatgcggat cacatccaag ccggactggt ctgccagctt
      181 ctgcaccagc gatgtgatct cctccaccga cttgctgttg acattttcct cgcgcacagc
      241 cccgttaact ggcagaggga cgtgggaatg agtggaagcc gccaggtcgg aagtcaaaca
      301 agtagaatcc agcgggcaag cagggatccc accctcccgc cctagcccgg ccccactcac
      361 ggtattcggc cactattctc ggcacagcgc acgggcgagg gttcaagtat attacgactc
      421 ctgggttccg tcgggcgaag tccgtcactt cgcgttccac gaactccctg gggacccaac
      481 gaagggccaa caggcagtgg caagacaaca ttcatcagtg agtatgccct ggacttgtgt
      541 acccagggag tgaacacact gtggggtagc tttgagatca gcaatgtgag actagcccgg
      601 gtcatgctga ctcagtttgc tgtgacacgg ctagaagaac aactggacaa gtatgaagag
      661 tgggcagacc gttttgagga cctgcctctc tatttcatga ctttccacgg acaacagagc
      721 atcaggtctg tcatagacac aatgcaacat gctgtctacg tctatgacgt ttgtcatgta
      781 gtcatcgaca acttgcagtt catgatgggt catgagcagc tctctactga caggatcgca
      841 gctcaagact acattgttgg agcctttcgg aagtttgcca cagacaatag ctgccacgtg
      901 actctggtta ttcacccacg gaaagaagat gacgacaagg aactacagac agcatccatt
      961 tttggctcag ccaaagccag ccaagaagca gacaatgttc tgatcttgca ggacaggaag
     1021 ctggtgactg ggcctgggaa acggtatctg caggtgtcca aaaatcgctt tgatggagac
     1081 gtaggcgtct tcccacttga gttcaacaag agttccctta ccttctccat cccacctaag
     1141 agcaaagccc gactcaagaa gattaaggat gacaatggac tagtggccaa gaagtcctcc
     1201 tctggaaaaa aagggtctgc gcaccagaac tctgagactt gcataggcca ggacccctgc
     1261 cagccagata cctccccgtc ctcaaggcat aagaattgat ctgaggtgct tatcctgtgc
     1321 tgtcagagcc tcaaagctgg accatggaga gaagctgtga gcctgcagtg cctgccccct
     1381 tgatgccgat tccactgtgt gctgctgcct tggacagcgg gagctaggac tcttggtgga
     1441 gccttttcca gttgaatgaa gcatttctat ggcctctg
//
