LOCUS       NM_001109119            1603 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus tubulin, beta 2A class IIa (Tubb2a), mRNA.
ACCESSION   NM_001109119 XM_001060757 XM_574013
VERSION     NM_001109119.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1603)
  AUTHORS   Chiasserini,D., van Weering,J.R., Piersma,S.R., Pham,T.V.,
            Malekzadeh,A., Teunissen,C.E., de Wit,H. and Jimenez,C.R.
  TITLE     Proteomic analysis of cerebrospinal fluid extracellular vesicles: a
            comprehensive dataset
  JOURNAL   J Proteomics 106, 191-204 (2014)
   PUBMED   24769233
REFERENCE   2  (bases 1 to 1603)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   3  (bases 1 to 1603)
  AUTHORS   Bharti,P., Schliebs,W., Schievelbusch,T., Neuhaus,A., David,C.,
            Kock,K., Herrmann,C., Meyer,H.E., Wiese,S., Warscheid,B., Theiss,C.
            and Erdmann,R.
  TITLE     PEX14 is required for microtubule-based peroxisome motility in
            human cells
  JOURNAL   J Cell Sci 124 (Pt 10), 1759-1768 (2011)
   PUBMED   21525035
REFERENCE   4  (bases 1 to 1603)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   5  (bases 1 to 1603)
  AUTHORS   Ginzburg,I., Teichman,A., Dodemont,H.J., Behar,L. and Littauer,U.Z.
  TITLE     Regulation of three beta-tubulin mRNAs during rat brain development
  JOURNAL   EMBO J 4 (13B), 3667-3673 (1985)
   PUBMED   2868892
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473977.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_574013.2, XM_001060757.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1603
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p12"
     gene            1..1603
                     /gene="Tubb2a"
                     /gene_synonym="Tubb2b"
                     /note="tubulin, beta 2A class IIa"
                     /db_xref="GeneID:498736"
                     /db_xref="RGD:1588452"
     exon            1..134
                     /gene="Tubb2a"
                     /gene_synonym="Tubb2b"
                     /inference="alignment:Splign:2.1.0"
     CDS             78..1415
                     /gene="Tubb2a"
                     /gene_synonym="Tubb2b"
                     /note="Tubulin beta-2B chain; T beta-15; tubulin beta-2A
                     chain pseudogene"
                     /codon_start=1
                     /product="tubulin beta-2A chain"
                     /protein_id="NP_001102589.1"
                     /db_xref="GeneID:498736"
                     /db_xref="RGD:1588452"
                     /translation="MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQL
                     ERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWA
                     KGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYP
                     DRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLT
                     TPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSR
                     GSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQ
                     NKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRK
                     AFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEEGEDEA"
     exon            135..243
                     /gene="Tubb2a"
                     /gene_synonym="Tubb2b"
                     /inference="alignment:Splign:2.1.0"
     exon            244..354
                     /gene="Tubb2a"
                     /gene_synonym="Tubb2b"
                     /inference="alignment:Splign:2.1.0"
     exon            355..1603
                     /gene="Tubb2a"
                     /gene_synonym="Tubb2b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcttttgct ctccttagcc ctcggtccac gcactgctcc tagggcaaga gccttcacct
       61 cttctacagc caacaccatg cgcgagatcg tgcacatcca ggcgggccaa tgcggcaacc
      121 agatcggcgc taagttttgg gaggtgataa gcgatgagca tggcatcgac cccactggca
      181 gttaccatgg cgacagtgac ttgcagctgg agagaatcaa tgtgtactac aatgaagctg
      241 ctggcaacaa atatgtacct cgggccatcc tagtggacct ggagccaggc accatggact
      301 cagtgaggtc gggaccattc ggccagatct tcaggccaga caactttgtg ttcggtcaga
      361 gtggtgcagg aaataactgg gcaaagggcc actacacaga gggtgccgag ctggtggact
      421 ctgtcctgga tgtggtgagg aaggagtcag aaagctgtga ctgtctccag ggcttccagc
      481 tgacccactc actgggggga ggcactggct caggcatggg gaccctgctc atcagcaaga
      541 tcagagaaga gtacccagac cgcatcatga acaccttcag cgtcatgccc tcacccaagg
      601 tctctgacac tgtggtggag ccctataatg ccaccctctc cgtgcaccag ctggtagaga
      661 acacagatga aacctattcc attgacaatg aggctctgta tgacatctgc ttccgcaccc
      721 tgaagctgac cacgcccacc tatggcgatc tcaaccacct ggtgtcagcc accatgagtg
      781 gagtgaccac ctgcctgcgc ttccctggcc agctgaacgc agacctgcgc aagctggctg
      841 tgaacatggt gcccttcccg cgcctgcact tcttcatgcc aggcttcgca cctctgacca
      901 gcaggggcag ccagcagtac cgagccctga cagtgcccga gctcacccag cagatgttcg
      961 actccaagaa catgatggct gcctgcgacc cacgccatgg ccgctacctg accgtagccg
     1021 ccattttccg gggccgcatg tccatgaagg aggtggatga gcagatgctc aacgtgcaga
     1081 acaagaacag cagctacttc gtggagtgga tccccaacaa tgtgaagacg gccgtgtgtg
     1141 acatccctcc tcgtggcctc aagatgtcag ccaccttcat tggcaacagc accgccatcc
     1201 aggagctgtt caagcgcatc tcggagcagt tcactgccat gttcaggcgc aaggctttcc
     1261 tgcactggta cacgggcgag ggcatggacg agatggagtt caccgaggca gagagcaaca
     1321 tgaatgacct ggtgtctgag taccagcagt accaggatgc cacggctgat gagcagggcg
     1381 agttcgagga ggaggagggc gaggatgagg cttaagaact tctcggatac attgtgcacc
     1441 cttagtgaac ttctgttgtc ctccagcatg gtctttctat ttgtaaatta tggtgctcag
     1501 tttgcctctg tctgaaattc actgttgatg taatagtgtg aacctccttt caagattaca
     1561 gtattgtctc agaaatctat atgaataaaa aagcatgtgt ata
//
