LOCUS       NM_001007004            1478 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus tubulin, alpha 4A (Tuba4a), mRNA.
ACCESSION   NM_001007004 XM_237302
VERSION     NM_001007004.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1478)
  AUTHORS   Kaczmarski,W., Barua,M., Mazur-Kolecka,B., Frackowiak,J.,
            Dowjat,W., Mehta,P., Bolton,D., Hwang,Y.W., Rabe,A., Albertini,G.
            and Wegiel,J.
  TITLE     Intracellular distribution of differentially phosphorylated
            dual-specificity tyrosine phosphorylation-regulated kinase 1A
            (DYRK1A)
  JOURNAL   J Neurosci Res 92 (2), 162-173 (2014)
   PUBMED   24327345
REFERENCE   2  (bases 1 to 1478)
  AUTHORS   Saito,T.T., Lui,D.Y., Kim,H.M., Meyer,K. and Colaiacovo,M.P.
  TITLE     Interplay between structure-specific endonucleases for crossover
            control during Caenorhabditis elegans meiosis
  JOURNAL   PLoS Genet 9 (7), e1003586 (2013)
   PUBMED   23874210
REFERENCE   3  (bases 1 to 1478)
  AUTHORS   Bharti,P., Schliebs,W., Schievelbusch,T., Neuhaus,A., David,C.,
            Kock,K., Herrmann,C., Meyer,H.E., Wiese,S., Warscheid,B., Theiss,C.
            and Erdmann,R.
  TITLE     PEX14 is required for microtubule-based peroxisome motility in
            human cells
  JOURNAL   J Cell Sci 124 (Pt 10), 1759-1768 (2011)
   PUBMED   21525035
REFERENCE   4  (bases 1 to 1478)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   5  (bases 1 to 1478)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   6  (bases 1 to 1478)
  AUTHORS   Khodiyar,V.K., Maltais,L.J., Ruef,B.J., Sneddon,K.M., Smith,J.R.,
            Shimoyama,M., Cabral,F., Dumontet,C., Dutcher,S.K., Harvey,R.J.,
            Lafanechere,L., Murray,J.M., Nogales,E., Piquemal,D., Stanchi,F.,
            Povey,S. and Lovering,R.C.
  TITLE     A revised nomenclature for the human and rodent alpha-tubulin gene
            family
  JOURNAL   Genomics 90 (2), 285-289 (2007)
   PUBMED   17543498
  REMARK    Erratum:[Genomics. 2009 Apr;93(4):397. Ruef, Barbara J [added]]
REFERENCE   7  (bases 1 to 1478)
  AUTHORS   Villasante,A., Wang,D., Dobner,P., Dolph,P., Lewis,S.A. and
            Cowan,N.J.
  TITLE     Six mouse alpha-tubulin mRNAs encode five distinct isotypes:
            testis-specific expression of two sister genes
  JOURNAL   Mol Cell Biol 6 (7), 2409-2419 (1986)
   PUBMED   3785200
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Apr 13, 2023 this sequence version replaced NM_001007004.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ235001.1, FQ234185.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840110, SAMN12840115
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-61                JAXUCZ010000009.1  84162524-84162584   c
            62-284              JAXUCZ010000009.1  84160543-84160765   c
            285-433             JAXUCZ010000009.1  84160140-84160288   c
            434-1478            JAXUCZ010000009.1  84158871-84159915   c
FEATURES             Location/Qualifiers
     source          1..1478
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q33"
     gene            1..1478
                     /gene="Tuba4a"
                     /gene_synonym="Tuba4"
                     /note="tubulin, alpha 4A"
                     /db_xref="GeneID:316531"
                     /db_xref="RGD:1359623"
     exon            1..61
                     /gene="Tuba4a"
                     /gene_synonym="Tuba4"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..1405
                     /gene="Tuba4a"
                     /gene_synonym="Tuba4"
                     /note="alpha-tubulin 4; tubulin alpha-4 chain; tubulin,
                     alpha 4"
                     /codon_start=1
                     /product="tubulin alpha-4A chain"
                     /protein_id="NP_001007005.1"
                     /db_xref="GeneID:316531"
                     /db_xref="RGD:1359623"
                     /translation="MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGG
                     GDDSFTTFFCETGAGKHVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANN
                     YARGHYTIGKEIIDPVLDRIRKLSDQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVD
                     YGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLD
                     IERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVI
                     SAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAA
                     IKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLD
                     HKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGIDSYEDEDEGEE"
     exon            62..284
                     /gene="Tuba4a"
                     /gene_synonym="Tuba4"
                     /inference="alignment:Splign:2.1.0"
     exon            285..433
                     /gene="Tuba4a"
                     /gene_synonym="Tuba4"
                     /inference="alignment:Splign:2.1.0"
     exon            434..1478
                     /gene="Tuba4a"
                     /gene_synonym="Tuba4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agatctcacc gagacccgtg accccgactc tacgtgagac gtacatccca aactcatcat
       61 gcgtgagtgc atttcagtcc atgtgggcca ggcaggtgtc cagatgggca atgcctgctg
      121 ggagctctac tgcctggaac atgggattca gcctgatggg cagatgccta gcgataagac
      181 cattggtgga ggggatgact ccttcaccac cttcttctgt gaaactggag ctggaaaaca
      241 tgtgcctcgg gcagtctttg tggatctgga gcctactgta attgatgaga tccgaaatgg
      301 cccgtaccgc cagctcttcc acccagaaca gcttatcact gggaaggaag atgcagccaa
      361 caactatgcc cgtggtcact acaccattgg caaggagatc atcgacccag tgctggaccg
      421 gatccgcaag ctgtctgatc agtgtacagg actccagggc tttctggtgt tccacagctt
      481 tggaggaggc actggctctg gcttcacctc tctgctgatg gaacggcttt ctgttgacta
      541 tggcaagaag tccaagctgg agttctccat ctacccagcc ccacaagtgt ccacggctgt
      601 agtggagccc tataactcca tcctgaccac ccataccacc ctggaacact cggactgtgc
      661 cttcatggtg gacaacgagg ccatttatga catctgtcgc cgtaacctgg atattgagcg
      721 cccaacctat accaacctca accgcctcat cagccaaatt gtctcctcca tcacagcttc
      781 cttgcgcttt gatggggccc tcaatgtgga cctgacagag ttccagacca acctggtacc
      841 ctaccctcgc atccacttcc ccttggctac ctacgcacca gtcatttctg cagagaaggc
      901 ctaccatgag cagctgtcag tggcagagat caccaatgcc tgttttgagc ctgccaacca
      961 gatggtgaaa tgtgaccctc ggcatggcaa gtacatggcc tgctgcctgc tgtaccgggg
     1021 agatgtggtg cccaaggatg tgaacgctgc catcgctgcc atcaagacga agcgcagcat
     1081 ccagtttgtg gactggtgcc ccacaggctt caaggtcggt atcaactacc agcctcccac
     1141 cgtggtgcct gggggcgacc tggccaaggt gcagcgtgca gtgtgcatgc tgagcaacac
     1201 aaccgccatt gctgaagcct gggcccgcct ggaccacaag tttgacttga tgtatgccaa
     1261 gagggctttt gtacactggt atgtgggtga gggaatggag gagggggagt tctccgaggc
     1321 tcgagaggat atggctgccc tggagaaaga ttatgaggaa gtaggcatcg actcctatga
     1381 ggacgaggat gagggagaag aatagacagc tacttggagc cctgttcact gtgtttattg
     1441 caaaatcctt tcgaaataaa cagtctcctt gcatggtt
//
