LOCUS       NM_001011995            1559 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus tubulin, alpha 1C (Tuba1c), mRNA.
ACCESSION   NM_001011995 XM_237718
VERSION     NM_001011995.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1559)
  AUTHORS   Todd,M.A. and Picketts,D.J.
  TITLE     PHF6 interacts with the nucleosome remodeling and deacetylation
            (NuRD) complex
  JOURNAL   J Proteome Res 11 (8), 4326-4337 (2012)
   PUBMED   22720776
REFERENCE   2  (bases 1 to 1559)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   3  (bases 1 to 1559)
  AUTHORS   Kesimer,M., Scull,M., Brighton,B., DeMaria,G., Burns,K., O'Neal,W.,
            Pickles,R.J. and Sheehan,J.K.
  TITLE     Characterization of exosome-like vesicles released from human
            tracheobronchial ciliated epithelium: a possible role in innate
            defense
  JOURNAL   FASEB J 23 (6), 1858-1868 (2009)
   PUBMED   19190083
REFERENCE   4  (bases 1 to 1559)
  AUTHORS   Zhao,M., Ko,S.Y., Liu,J.H., Chen,D., Zhang,J., Wang,B.,
            Harris,S.E., Oyajobi,B.O. and Mundy,G.R.
  TITLE     Inhibition of microtubule assembly in osteoblasts stimulates bone
            morphogenetic protein 2 expression and bone formation through
            transcription factor Gli2
  JOURNAL   Mol Cell Biol 29 (5), 1291-1305 (2009)
   PUBMED   19103752
REFERENCE   5  (bases 1 to 1559)
  AUTHORS   Khodiyar,V.K., Maltais,L.J., Ruef,B.J., Sneddon,K.M., Smith,J.R.,
            Shimoyama,M., Cabral,F., Dumontet,C., Dutcher,S.K., Harvey,R.J.,
            Lafanechere,L., Murray,J.M., Nogales,E., Piquemal,D., Stanchi,F.,
            Povey,S. and Lovering,R.C.
  TITLE     A revised nomenclature for the human and rodent alpha-tubulin gene
            family
  JOURNAL   Genomics 90 (2), 285-289 (2007)
   PUBMED   17543498
  REMARK    Erratum:[Genomics. 2009 Apr;93(4):397. Ruef, Barbara J [added]]
REFERENCE   6  (bases 1 to 1559)
  AUTHORS   Ledesma,M.D., Da Silva,J.S., Schevchenko,A., Wilm,M. and Dotti,C.G.
  TITLE     Proteomic characterisation of neuronal sphingolipid-cholesterol
            microdomains: role in plasminogen activation
  JOURNAL   Brain Res 987 (1), 107-116 (2003)
   PUBMED   14499952
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC078829.1.
            
            On Feb 11, 2005 this sequence version replaced XM_237718.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC078829.1, FQ222005.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1559
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     gene            1..1559
                     /gene="Tuba1c"
                     /gene_synonym="Tuba6"
                     /note="tubulin, alpha 1C"
                     /db_xref="GeneID:300218"
                     /db_xref="RGD:1307226"
     exon            1..85
                     /gene="Tuba1c"
                     /gene_synonym="Tuba6"
                     /inference="alignment:Splign:2.1.0"
     CDS             83..1432
                     /gene="Tuba1c"
                     /gene_synonym="Tuba6"
                     /note="alpha-tubulin 6; tubulin alpha-6 chain; tubulin,
                     alpha 6; tubulin alpha-1C chain-like"
                     /codon_start=1
                     /product="tubulin alpha-1C chain"
                     /protein_id="NP_001011995.1"
                     /db_xref="GeneID:300218"
                     /db_xref="RGD:1307226"
                     /translation="MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGG
                     GDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANN
                     YARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVD
                     YGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLD
                     IERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVI
                     SAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAT
                     IKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLARVQRAVCMLSNTTAIAEAWARLD
                     HKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSAEGDDEGEEY"
     exon            86..308
                     /gene="Tuba1c"
                     /gene_synonym="Tuba6"
                     /inference="alignment:Splign:2.1.0"
     exon            309..457
                     /gene="Tuba1c"
                     /gene_synonym="Tuba6"
                     /inference="alignment:Splign:2.1.0"
     exon            458..1536
                     /gene="Tuba1c"
                     /gene_synonym="Tuba6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccttggtagt ctgctagtgg gagaccttcg tcacccccct cttcacttcc tcagttttcg
       61 cggaccactt caaggactaa atatgcgtga gtgcatctcc atccacgttg gccaggctgg
      121 tgtccagatc ggcaatgcct gctgggagct ctactgcctg gaacatggca tccagcctga
      181 tggccagatg ccaagtgaca agaccattgg gggaggagat gactccttca acaccttctt
      241 cagtgagaca ggagctggca agcacgtgcc ccgggcggtg ttcgtagacc tggaacccac
      301 agttattgat gaagttcgaa ctggcaccta ccgccagctc ttccacccag agcagctcat
      361 cacaggcaag gaagatgctg ccaataacta tgcccgtggc cactacacca ttggcaagga
      421 gatcattgac cttgtcttgg acagaattcg caagctggct gaccagtgca cgggtctcca
      481 gggcttcttg gttttccaca gctttggtgg gggaactggc tctgggttca cctccctgct
      541 gatggagagg ctctctgtcg actacggaaa gaagtccaag ctggagttct ccatttaccc
      601 agccccccag gtttccactg ctgtggttga gccctacaat tccatcctca ccacccacac
      661 caccctggag cactctgatt gtgccttcat ggtagacaat gaggccatct atgacatctg
      721 tcgtagaaac ctcgacattg agcgcccaac ctacactaac cttaaccgcc ttattagcca
      781 gattgtgtct tccatcactg cttccctcag atttgatggg gccctgaatg ttgatctgac
      841 agaattccag accaacctgg tgccctaccc tcgaatccac ttccctctgg ccacttatgc
      901 ccctgtcatc tctgctgaga aagcctacca tgagcaactt acagtagcag agatcaccaa
      961 tgcctgcttt gagccagcca accagatggt gaaatgtgac cctcgccatg gtaaatacat
     1021 ggcttgctgc ctgctgtacc gtggtgatgt ggtccccaag gatgtcaatg ctgccattgc
     1081 caccatcaag accaagcgta ccatccagtt tgtggactgg tgccccactg gcttcaaggt
     1141 tggcattaat taccagcctc ccactgtggt acctggtggc gacctggcca gggtgcagag
     1201 agctgtgtgt atgctgagca acaccacagc cattgctgag gcctgggctc gcctggatca
     1261 caagtttgat ctgatgtatg ccaagcgtgc ctttgtgcac tggtatgtgg gtgagggcat
     1321 ggaggagggg gagttctctg aggcccgtga ggatatggct gccctagaga aggattatga
     1381 ggaggttggg gcagatagtg ctgaaggaga cgatgagggt gaagaatatt aactcctgtg
     1441 ctgcaacttt acacctctgt ggtctcatct ttgtccttgc gtgcgtttta actgtcctat
     1501 actgtcaata aaggtgtttc cgttttaagt gggaaaaaaa aaaaaaaaaa aaaaaaaaa
//
