LOCUS       XM_006254457             758 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus transthyretin (Ttr), transcript
            variant X1, mRNA.
ACCESSION   XM_006254457
VERSION     XM_006254457.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051353.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006254457.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..758
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..758
                     /gene="Ttr"
                     /gene_synonym="Lr1; Tbpa; TT"
                     /note="transthyretin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 182 mRNAs, 136 ESTs, 5
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 10 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:24856"
                     /db_xref="RGD:3916"
     CDS             169..612
                     /gene="Ttr"
                     /gene_synonym="Lr1; Tbpa; TT"
                     /codon_start=1
                     /product="transthyretin isoform X1"
                     /protein_id="XP_006254519.1"
                     /db_xref="GeneID:24856"
                     /db_xref="RGD:3916"
                     /translation="MASLRLFLLCLAGLIFASEAGPGGAGESKCPLMVKVLDAVRGSP
                     AVDVAVKVFKKTADGSWEPFASGKTAESGELHGLTTDEKFTEGVYRVELDTKSYWKAL
                     GISPFHEYAEVVFTANDSGHRHYTIAALLSPYSYSTTAVVSNPQN"
ORIGIN      
        1 ttggggagag aagattccag gtcctgtgtc tgaagagaaa tctctcaaag agaatcagca
       61 ggtttggagt cagattggca gggatcagca ggctgccttg ggaggagggg gtatataagc
      121 cccttcacca ggagaagtca tcgtagagat ccgctggctc ctgacaggat ggcttccctt
      181 cgcctgttcc tcctctgcct cgctggactg atatttgcgt ctgaagctgg ccctgggggt
      241 gctggagaat ccaagtgtcc tctgatggtc aaagtcctgg atgctgtccg aggcagccct
      301 gctgtcgatg tggccgtgaa agtgttcaaa aagactgcag acggaagctg ggagccgttt
      361 gcctctggga agaccgccga gtctggagag ctgcacgggc tcaccacaga tgagaagttc
      421 acggaagggg tgtacagggt agaactggac accaaatcgt actggaaggc tcttggcatt
      481 tccccattcc atgaatacgc agaggtggtt ttcacagcca atgactctgg tcatcgccac
      541 tacaccatcg cagccctgct cagcccgtac tcctacagca ccactgctgt cgtcagtaac
      601 ccccagaact gagggaccca gcccaggagg accaggatct tgccaaagca gtagcttccc
      661 atttgtactg aaacagtgtt cttgctctat aaaccgtgtt agcaactcgg gaagatgccg
      721 tgaaacgttc ttattaaacc acctttattt cattcaaa
//
