LOCUS       NM_001108640            2906 bp    mRNA    linear   ROD 15-APR-2024
DEFINITION  Rattus norvegicus tubulin tyrosine ligase like 3 (Ttll3),
            transcript variant 1, mRNA.
ACCESSION   NM_001108640 XM_342736
VERSION     NM_001108640.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2906)
  AUTHORS   Bosch Grau,M., Gonzalez Curto,G., Rocha,C., Magiera,M.M., Marques
            Sousa,P., Giordano,T., Spassky,N. and Janke,C.
  TITLE     Tubulin glycylases and glutamylases have distinct functions in
            stabilization and motility of ependymal cilia
  JOURNAL   J Cell Biol 202 (3), 441-451 (2013)
   PUBMED   23897886
REFERENCE   2  (bases 1 to 2906)
  AUTHORS   Rogowski,K., Juge,F., van Dijk,J., Wloga,D., Strub,J.M.,
            Levilliers,N., Thomas,D., Bre,M.H., Van Dorsselaer,A., Gaertig,J.
            and Janke,C.
  TITLE     Evolutionary divergence of enzymatic mechanisms for
            posttranslational polyglycylation
  JOURNAL   Cell 137 (6), 1076-1087 (2009)
   PUBMED   19524510
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CV126544.1 and
            BC168907.1.
            
            On Dec 23, 2009 this sequence version replaced NM_001108640.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-142               CV126544.1         1-142
            143-2906            BC168907.1         1-2764
FEATURES             Location/Qualifiers
     source          1..2906
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..2906
                     /gene="Ttll3"
                     /note="tubulin tyrosine ligase like 3"
                     /db_xref="GeneID:362415"
                     /db_xref="RGD:1311255"
     exon            1..82
                     /gene="Ttll3"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..2319
                     /gene="Ttll3"
                     /note="isoform 1 is encoded by transcript variant 1;
                     tubulin monoglycylase TTLL3; tubulin tyrosine ligase-like
                     family, member 3"
                     /codon_start=1
                     /product="tubulin monoglycylase TTLL3 isoform 1"
                     /protein_id="NP_001102110.2"
                     /db_xref="GeneID:362415"
                     /db_xref="RGD:1311255"
                     /translation="MAAGHSTLKRHPYSDSLLLWRGFTKGTPHHMGRLRNAKIHVERA
                     VKQKKIFMIHGRYPVIRCLLRQRGWVEKKMVHPPGTILPPPSKDLDSSMLGDSDATED
                     EDEEESEMFRESQLLDLDGFLEFDDLDGIHALMSRMVRNETPYLIWTTRRDVLDCRFL
                     SKDQMINHYARAGSFTTKVGLCLNLRNLPWFDEADADSFFPRCYRLGAEDDKKAFIED
                     FWLTAARNVLKLVVKLEGRSQSIPIQAREEEALEDTQPKKQEKKPVTVSSDFVDEALS
                     ACEEHLSNIAHKDIDKDPNAPLYLSPDDWSLFLQRYYQIVHQGAELRYLEVQVQRCED
                     ILQQLRAVVPQIDMEGDRNIWIVKPGAKSRGRGITCMDHLDEMLKLVDCNPMLMKDGK
                     WIVQKYIERPLLIFGTKFDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPFSLKNLDNSV
                     HLCNNSIQRHLEASCHRHPMLPPDNMWSSQRFQAHLQEVDAPKAWSTVIVPGMKAAVI
                     HALQTSQDNVQCRKASFELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQ
                     ADTLRVVIDRRMDRSCDTGAFELIYKQPAVEVPQYVGIRLVVEGSTIKKPMAVGHRRT
                     GVLCSSLPHLLTQQGSGESKGSGSPTHRSAFRKNARVESLGHTTAAEKPETTATTPVP
                     GKGKKAEVAGSLRTLPEVAQLRRGRAGMQTQTLSTSLVSTSRPGCLLPVCTDPRAGST
                     DSSTASWWALRLCQPQARP"
     exon            83..177
                     /gene="Ttll3"
                     /inference="alignment:Splign:2.1.0"
     exon            178..346
                     /gene="Ttll3"
                     /inference="alignment:Splign:2.1.0"
     exon            347..444
                     /gene="Ttll3"
                     /inference="alignment:Splign:2.1.0"
     exon            445..573
                     /gene="Ttll3"
                     /inference="alignment:Splign:2.1.0"
     exon            574..688
                     /gene="Ttll3"
                     /inference="alignment:Splign:2.1.0"
     exon            689..793
                     /gene="Ttll3"
                     /inference="alignment:Splign:2.1.0"
     exon            794..989
                     /gene="Ttll3"
                     /inference="alignment:Splign:2.1.0"
     exon            990..1138
                     /gene="Ttll3"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1382
                     /gene="Ttll3"
                     /inference="alignment:Splign:2.1.0"
     exon            1383..1818
                     /gene="Ttll3"
                     /inference="alignment:Splign:2.1.0"
     exon            1819..2101
                     /gene="Ttll3"
                     /inference="alignment:Splign:2.1.0"
     exon            2102..2178
                     /gene="Ttll3"
                     /inference="alignment:Splign:2.1.0"
     exon            2179..2906
                     /gene="Ttll3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttagaggtac tcctcgtgaa ggtgggagat cagaaggaaa tggcagctgg tcactcaacc
       61 ctcaaaagac atccttattc cgattcccta ctcctctggc gaggattcac caagggaact
      121 cctcaccata tgggccgact cagaaacgcc aaaatccacg tagagagagc cgtcaagcag
      181 aagaagatct ttatgattca tggacgatac ccagtgatcc ggtgtctctt gcgccagaga
      241 ggctgggtag agaagaagat ggtgcatccc ccaggcacga tcctgccacc accttcgaag
      301 gatctagaca gctccatgct gggtgacagc gatgccacag aggatgagga cgaagaagag
      361 agtgagatgt ttcgggagtc gcagctgttg gacttggatg gtttcttgga attcgacgac
      421 ctagatggga tacatgcttt gatgtcccgc atggttcgaa acgagacccc ttacctgatc
      481 tggaccactc ggcgagacgt gctagattgt cgcttccttt ccaaggatca gatgataaac
      541 cattatgccc gtgccggctc cttcactaca aaggtgggcc tttgtctcaa cctccggaat
      601 ctgccatggt ttgatgaggc tgatgctgac tccttcttcc cacgatgcta ccgactgggg
      661 gcagaggatg acaagaaagc cttcatagag gacttctggc tgacagctgc ccgcaacgtt
      721 ctcaagctgg tggtgaagtt ggaagggagg tcacagtcta tccccatcca ggcaagagag
      781 gaagaggccc tagaagatac acagcccaag aaacaggaga agaagccagt gacggtgtct
      841 tcagactttg tggatgaggc tctgagtgca tgcgaggaac atctcagcaa catagcccac
      901 aaagacatcg acaaggaccc caacgcccca ctgtacctca gccctgacga ctggtccctc
      961 ttccttcagc gctactacca aatagtgcat caaggggcag aactcagata cctggaggtc
     1021 caagtccagc gctgtgaaga catcctacag cagcttcggg ccgtggtacc ccagatagac
     1081 atggaggggg atcggaacat ctggatcgtg aagcccggag ccaagtcccg aggccgaggg
     1141 attacatgca tggaccacct ggatgagatg ctgaagctgg tggactgcaa ccccatgctg
     1201 atgaaggatg gcaagtggat tgtgcagaag tacattgagc ggcccctgct gatcttcggc
     1261 accaagtttg acctgaggca gtggttcctg gtgaccgact ggaacccact cactgtgtgg
     1321 ttctaccggg acagctacat ccgcttctcc acacagcctt tctccttgaa gaacctggac
     1381 aactctgtgc acctgtgtaa caactccatc cagagacact tggaggcttc ctgtcaccga
     1441 cacccaatgc tgcctccgga taacatgtgg tccagccaga ggtttcaggc ccacttgcag
     1501 gaggtagatg ccccaaaggc gtggtccact gtcattgtgc ctggcatgaa ggctgccgtg
     1561 atccatgccc tgcagacctc ccaggacaac gtgcagtgtc ggaaggccag ctttgaactc
     1621 tatggggctg actttgtgtt tggggaagac ttccagccct ggctgattga aatcaatgcc
     1681 agccccacca tggcaccttc cacagctgtc actgcccgcc tctgtgctgg tgtgcaagca
     1741 gataccctgc gtgtggtcat cgaccggcga atggaccgca gctgcgatac aggagccttt
     1801 gagctcatct ataagcagcc tgctgtggag gtgccccagt acgtgggtat ccggctcgta
     1861 gtagagggct ctaccatcaa gaagcccatg gcagtgggac atcggcggac aggggtcctc
     1921 tgctcatcac tccctcatct gctgacccag caaggctctg gggaaagcaa gggctcaggc
     1981 tcccctaccc acaggtcagc ttttaggaaa aatgctaggg tcgagagcct gggacacacc
     2041 accgccgccg agaagccaga aactactgcc accacaccgg tccctggaaa ggggaagaaa
     2101 gccgaggtag caggaagttt aaggacgttg cccgaggttg cacagctcag aaggggcaga
     2161 gctgggatgc agacccagac cctttccact tccctagtct ccacatcaag gcctggctgc
     2221 cttctccccg tgtgcaccga ccccagagcc gggtccacag actccagcac agccagctgg
     2281 tgggctctaa ggctctgtca accacaggca aggccttgat gactctacct actgccaagg
     2341 ttccgatgtc cttcccacct caccctgacc tcgaactggc acctagcatg ctgaagccca
     2401 gaaaggtggg ctttgagcta agctgcacac cctagtgggt agtgctgagc agagggattg
     2461 gggcagaagg gcacaggcag agggcagcac caagaccaag cagcgcacca gggaagggct
     2521 tgtcttccac agaaccctgt tccaagacag aggcctgatc atctctctct tcctcccctc
     2581 ctttacaccg aggctgctat tcccctgcac cttcgaggcc cccactttgg aagtgcctct
     2641 tggcctctga cctttgaagc cggacttctt cctagcaccc acaggaaagt caagtccaaa
     2701 ggcaagttca aggccagact cggcaacaga cccagggctg aggcataccc cacgaagagg
     2761 ctaagtctcc ccagcccctt aacccttatt ttggtgtccc aaagtctggg gcctgtaggg
     2821 gccacgaggc taaagaaacc cctgctctga acttcactgc cccatcctgg atccagcatc
     2881 aaataaaaaa aaaaaaaaaa aaaaaa
//
