LOCUS       NM_001135922            2412 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus tubulin tyrosine ligase like 12 (Ttll12), mRNA.
ACCESSION   NM_001135922 XM_235528
VERSION     NM_001135922.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2412)
  AUTHORS   Ju,L.G., Zhu,Y., Lei,P.J., Yan,D., Zhu,K., Wang,X., Li,Q.L.,
            Li,X.J., Chen,J.W., Li,L.Y. and Wu,M.
  TITLE     TTLL12 Inhibits the Activation of Cellular Antiviral Signaling
            through Interaction with VISA/MAVS
  JOURNAL   J Immunol 198 (3), 1274-1284 (2017)
   PUBMED   28011935
REFERENCE   2  (bases 1 to 2412)
  AUTHORS   Brants,J., Semenchenko,K., Wasylyk,C., Robert,A., Carles,A.,
            Zambrano,A., Pradeau-Aubreton,K., Birck,C., Schalken,J.A., Poch,O.,
            de Mey,J. and Wasylyk,B.
  TITLE     Tubulin tyrosine ligase like 12, a TTLL family member with SET- and
            TTL-like domains and roles in histone and tubulin modifications and
            mitosis
  JOURNAL   PLoS One 7 (12), e51258 (2012)
   PUBMED   23251473
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Oct 17, 2008 this sequence version replaced XM_235528.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.28324.1,
                                           SRR26643294.30208.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-175               JAXUCZ010000007.1  116631070-116631244 c
            176-345             JAXUCZ010000007.1  116627563-116627732 c
            346-544             JAXUCZ010000007.1  116625365-116625563 c
            545-704             JAXUCZ010000007.1  116623985-116624144 c
            705-838             JAXUCZ010000007.1  116623762-116623895 c
            839-915             JAXUCZ010000007.1  116621308-116621384 c
            916-1032            JAXUCZ010000007.1  116618954-116619070 c
            1033-1227           JAXUCZ010000007.1  116618651-116618845 c
            1228-1339           JAXUCZ010000007.1  116618262-116618373 c
            1340-1491           JAXUCZ010000007.1  116617062-116617213 c
            1492-1573           JAXUCZ010000007.1  116616644-116616725 c
            1574-1642           JAXUCZ010000007.1  116614923-116614991 c
            1643-1781           JAXUCZ010000007.1  116613930-116614068 c
            1782-2412           JAXUCZ010000007.1  116612609-116613239 c
FEATURES             Location/Qualifiers
     source          1..2412
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..2412
                     /gene="Ttll12"
                     /gene_synonym="RGD1305319"
                     /note="tubulin tyrosine ligase like 12"
                     /db_xref="GeneID:300105"
                     /db_xref="RGD:1305319"
     exon            1..175
                     /gene="Ttll12"
                     /gene_synonym="RGD1305319"
                     /inference="alignment:Splign:2.1.0"
     CDS             14..1933
                     /gene="Ttll12"
                     /gene_synonym="RGD1305319"
                     /note="tubulin tyrosine ligase-like family, member 12"
                     /codon_start=1
                     /product="tubulin--tyrosine ligase-like protein 12"
                     /protein_id="NP_001129394.1"
                     /db_xref="GeneID:300105"
                     /db_xref="RGD:1305319"
                     /translation="MEGEPRSQPGSPGRAERLNARLLDEFVSLHGPALRASGVPERLW
                     GSLLHKLEHEVFDAGEMFGIMQVEEVEEAEDEAAREAQRKQPNPGGELCYKVIVTSEN
                     GVRADDPNSIFLIDHAWTCRVEHARKQLQQVPGLLHRMANLMGIEFHGEVPSPEVVAL
                     VLEEMWKFNQTYQLAHGTAEEKVPVWYIMDEFGSRIQHADMPSFATAPFFYMPQQVAY
                     TLLWPLRDLDTGEEVTRDYAYGEADPLIRKCMLLPWAPADMLDLSSSTPEPPAKYYQA
                     ILEENKEKLPLTISPVARPQGHIFRVHCDVQQVLSHLTHPRFTFTDSEADADVYFHFS
                     HFKDYTKLSQESPQVLLNQFPCENLLTVKDCLASIARRAGGPEGPPWLPRTFNLRTEL
                     PQFVSYFQHRERRGEDNHWICKPWNLARSLDTHVTNNLHSIIRHRESTPKVVSKYIES
                     PVLFFREDVGNVKFDIRYIVLLRSVRPLRLFVYDVFWLRFSNRPFALNDLDDYEKHFT
                     VMNYDPDVVLKQVHYNEFIPQFEKQNPEFPWSGVQAEIFKAFTELFEVACAKPPPMGL
                     CDYPSSRAIYAIDLMLKWDSHPDGKRVMQPQILEVNFNPDCERACKYHPSFFNDVFST
                     LFLDETDDCHVTRII"
     exon            176..345
                     /gene="Ttll12"
                     /gene_synonym="RGD1305319"
                     /inference="alignment:Splign:2.1.0"
     exon            346..544
                     /gene="Ttll12"
                     /gene_synonym="RGD1305319"
                     /inference="alignment:Splign:2.1.0"
     exon            545..704
                     /gene="Ttll12"
                     /gene_synonym="RGD1305319"
                     /inference="alignment:Splign:2.1.0"
     exon            705..838
                     /gene="Ttll12"
                     /gene_synonym="RGD1305319"
                     /inference="alignment:Splign:2.1.0"
     exon            839..915
                     /gene="Ttll12"
                     /gene_synonym="RGD1305319"
                     /inference="alignment:Splign:2.1.0"
     exon            916..1032
                     /gene="Ttll12"
                     /gene_synonym="RGD1305319"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1227
                     /gene="Ttll12"
                     /gene_synonym="RGD1305319"
                     /inference="alignment:Splign:2.1.0"
     exon            1228..1339
                     /gene="Ttll12"
                     /gene_synonym="RGD1305319"
                     /inference="alignment:Splign:2.1.0"
     exon            1340..1491
                     /gene="Ttll12"
                     /gene_synonym="RGD1305319"
                     /inference="alignment:Splign:2.1.0"
     exon            1492..1573
                     /gene="Ttll12"
                     /gene_synonym="RGD1305319"
                     /inference="alignment:Splign:2.1.0"
     exon            1574..1642
                     /gene="Ttll12"
                     /gene_synonym="RGD1305319"
                     /inference="alignment:Splign:2.1.0"
     exon            1643..1781
                     /gene="Ttll12"
                     /gene_synonym="RGD1305319"
                     /inference="alignment:Splign:2.1.0"
     exon            1782..2412
                     /gene="Ttll12"
                     /gene_synonym="RGD1305319"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcatccgagc accatggagg gcgaaccccg gtcgcagcct ggcagcccgg gccgcgccga
       61 gaggctgaac gcgcggctgc tggacgagtt cgtgtcgcta cacggacccg cgctacgcgc
      121 ctcaggcgtc ccagagcgac tatggggcag cctcctgcac aagctggagc acgaggtttt
      181 cgatgctggg gagatgtttg ggataatgca agtggaggag gtggaggagg ctgaggacga
      241 ggccgccagg gaggctcaga gaaagcagcc gaatcctggg ggcgagctgt gctacaaggt
      301 cattgtgacc agtgagaacg gcgtccgggc tgatgacccc aacagcatct tcctcatcga
      361 ccatgcctgg acgtgccgtg tggagcatgc acgcaaacag ctgcagcagg tgcctggact
      421 cctacaccgg atggccaacc tcatgggcat cgagttccat ggcgaagtgc ccagtccaga
      481 ggttgtggcc ctagtgctgg aggagatgtg gaaattcaac cagacctatc agctggccca
      541 tgggacagcc gaagagaagg tgccagtgtg gtacatcatg gacgagtttg gctcaaggat
      601 ccagcatgca gacatgccca gcttcgccac tgctcccttc ttctacatgc cccagcaggt
      661 ggcatacacg ctgctgtggc ccctaaggga cctagacaca ggcgaggagg tgacccggga
      721 ctatgcctac ggagaggcag accctctgat ccggaaatgc atgctgctgc cctgggcccc
      781 cgccgacatg ctggacctca gctcctctac gcctgagcct cccgccaagt actaccaggc
      841 cattttggag gaaaacaagg agaaactgcc actcaccatt agcccggtgg cacgtcccca
      901 gggccacatc ttcagagtcc actgcgatgt gcaacaggtg ctcagccacc tcacgcaccc
      961 tcgcttcacc ttcactgaca gcgaggccga cgccgacgtc tacttccatt tctcgcactt
     1021 caaggactac acgaaactca gccaagagag cccacaggta ctactcaacc agttcccctg
     1081 tgagaacctg ctgactgtta aggactgtct ggcctccatc gctcgccggg ctggaggtcc
     1141 tgagggtccc ccctggctac cccgaacctt caacctgcgc accgagctgc cccagttcgt
     1201 cagctatttc cagcaccgag agaggcgggg tgaagacaac cactggatct gcaagccttg
     1261 gaacctggcc cgcagcctgg acactcacgt caccaacaat ctccacagca tcatccgaca
     1321 ccgagagagc acccccaagg ttgtgtcaaa atacattgaa agtcccgtct tgttcttccg
     1381 agaagacgtg gggaacgtca agtttgacat ccgctacatt gtgctgctgc gctcagtgag
     1441 gccgctgagg ttgtttgtgt atgatgtgtt ctggctacgc ttctccaatc ggcctttcgc
     1501 cctcaatgac ctagacgact atgagaagca tttcaccgtc atgaactatg acccggatgt
     1561 ggtgctaaag caggtgcact ataatgagtt catcccccag tttgagaagc agaacccaga
     1621 gtttccttgg agtggtgtcc aggctgagat cttcaaggcc ttcacggagc tgtttgaagt
     1681 ggcatgtgcc aagccacccc ccatgggtct ctgcgactac ccctcatctc gggccatata
     1741 tgctattgac ctcatgctca agtgggacag ccatccagat ggaaagcggg tgatgcagcc
     1801 ccagatcctg gaggtgaact tcaaccctga ctgcgagcga gcctgcaagt accacccctc
     1861 gttcttcaac gatgtcttca gcaccttgtt tctggacgag accgacgact gccatgtcac
     1921 ccgcatcatc taggtgccca gagttctgcc cgtgctcgta gctggttcca gcctctgctc
     1981 atggaactgc ctctgcagcc ccagccatct ccttccctcc cttccccact tcctgagccg
     2041 tgttcctgct tcgtatgtgg gatgtcaggt ccatgtgtgg cagagctgga cagggagtgg
     2101 tgtcccaagg gctgggctct gccccggcac tctccatacc ccttaaccct ctcttctctg
     2161 aggagtctgc agctcagctc ttctggcatc cagagagttc gcagacaaag aggtgttctg
     2221 cagaaacagg gttccacgtg aagcctttgg gaaccccata tccaccaggg ccaaggagtg
     2281 ctctctcaga acctctgccc tcctgtgccg tggctgctgt aagcagggta caggaaccct
     2341 gtgttacacc cgagacccca gaacagccca ggggaaacaa acatttgcca acccagcctt
     2401 atgccttggc tc
//
