LOCUS       NM_001401371            3725 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus tetratricopeptide repeat domain 7B (Ttc7b),
            transcript variant 1, mRNA.
ACCESSION   NM_001401371
VERSION     NM_001401371.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3725)
  AUTHORS   Baskin,J.M., Wu,X., Christiano,R., Oh,M.S., Schauder,C.M.,
            Gazzerro,E., Messa,M., Baldassari,S., Assereto,S., Biancheri,R.,
            Zara,F., Minetti,C., Raimondi,A., Simons,M., Walther,T.C.,
            Reinisch,K.M. and De Camilli,P.
  TITLE     The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P
            synthesis at the plasma membrane
  JOURNAL   Nat Cell Biol 18 (1), 132-138 (2016)
   PUBMED   26571211
REFERENCE   2  (bases 1 to 3725)
  AUTHORS   Nakatsu,F., Baskin,J.M., Chung,J., Tanner,L.B., Shui,G., Lee,S.Y.,
            Pirruccello,M., Hao,M., Ingolia,N.T., Wenk,M.R. and De Camilli,P.
  TITLE     PtdIns4P synthesis by PI4KIIIalpha at the plasma membrane and its
            impact on plasma membrane identity
  JOURNAL   J Cell Biol 199 (6), 1003-1016 (2012)
   PUBMED   23229899
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643296.18437.1,
                                           SRR26643295.26298.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-267               JAXUCZ010000006.1  125528513-125528779 c
            268-422             JAXUCZ010000006.1  125506342-125506496 c
            423-591             JAXUCZ010000006.1  125501839-125502007 c
            592-722             JAXUCZ010000006.1  125475177-125475307 c
            723-844             JAXUCZ010000006.1  125463547-125463668 c
            845-923             JAXUCZ010000006.1  125434789-125434867 c
            924-1096            JAXUCZ010000006.1  125430269-125430441 c
            1097-1160           JAXUCZ010000006.1  125420805-125420868 c
            1161-1298           JAXUCZ010000006.1  125417267-125417404 c
            1299-1382           JAXUCZ010000006.1  125401812-125401895 c
            1383-1487           JAXUCZ010000006.1  125400798-125400902 c
            1488-1605           JAXUCZ010000006.1  125398994-125399111 c
            1606-1663           JAXUCZ010000006.1  125396855-125396912 c
            1664-1736           JAXUCZ010000006.1  125390635-125390707 c
            1737-1897           JAXUCZ010000006.1  125387888-125388048 c
            1898-2014           JAXUCZ010000006.1  125371941-125372057 c
            2015-2112           JAXUCZ010000006.1  125364624-125364721 c
            2113-2274           JAXUCZ010000006.1  125360647-125360808 c
            2275-2325           JAXUCZ010000006.1  125358076-125358126 c
            2326-2466           JAXUCZ010000006.1  125350170-125350310 c
            2467-2669           JAXUCZ010000006.1  125341524-125341726 c
            2670-3725           JAXUCZ010000006.1  125317011-125318066 c
FEATURES             Location/Qualifiers
     source          1..3725
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q32"
     gene            1..3725
                     /gene="Ttc7b"
                     /note="tetratricopeptide repeat domain 7B"
                     /db_xref="GeneID:362768"
                     /db_xref="RGD:1305920"
     exon            1..267
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     CDS             147..2891
                     /gene="Ttc7b"
                     /note="isoform 1 is encoded by transcript variant 1;
                     tetratricopeptide repeat protein 7B"
                     /codon_start=1
                     /product="tetratricopeptide repeat protein 7B isoform 1"
                     /protein_id="NP_001388300.1"
                     /db_xref="GeneID:362768"
                     /db_xref="RGD:1305920"
                     /translation="MATRKAGSRLETEIERCRSECQWERIPELVKQLSAKLIANDDMA
                     ELLLGESKLEQHLKEKPLRQGASPRGPRPQLTEVRKHLTAALDRGNLKSEFLQESNLV
                     MAKLNYVEGDYKEALNIYARVGLDDLPLMAVPPYRLRMIAEAYATKGLCLEKLPVSSS
                     TSNLHVDREQDVITCYEKAGDIALLYLQEIERVILTNIQNRSPKPGPAPHDQELGFFL
                     ETGLQRAHVLYFKNGNLTRGVGRFRELLRAVETRTTQNLRMTIARQLAEILLRGMCEQ
                     SYWNPLEEPPCQSPLDDPLRKGANTKTYTLPRRARVYSGENIFCPQENTEEALLLLLI
                     SESMANRDAVLSRIPEHKSDRLISLQSASVVYDLLTIALGRRGQYEMLSECLERAMKF
                     AFEEFHLWYQFALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCVGSLHWLEE
                     AEKFAKTVVDVGEKTSEFKAKGYLALGLTYSLQATDASLRGMQEVLQRKALLALQRAH
                     SLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHHH
                     DALNIIDMALSEYPENFILLFSKVKLESLCRGPDEALLTCKHMLQIWKSCYNLTNPSD
                     SGRGSSLLDRTIADRRQLNTITLPDFSDPETVSDSSSSSSISRTESPLHLFVSSPLHS
                     HPKPDIFVWPPAAHSLSDPGPHREPSLCNSPEAHFHGFPSLFSVSSVHATSVAASRVE
                     QALSEVASSLQSSAPKQGPLHPWMTLAQIWLHAAEVYIGIGKPAEATACTQEAANLFP
                     MSHNVLYMRGQVAELRGNFDEARRWYEEALSISPTHVKSMQRLALVLHQLGRYSLAEK
                     ILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATECFLTALELEASSPAVPFTVIPRVL
                     "
     exon            268..422
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            423..591
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            592..722
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            723..844
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            845..923
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            924..1096
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            1097..1160
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            1161..1298
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1382
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            1383..1487
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            1488..1605
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            1606..1663
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            1664..1736
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            1737..1897
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            1898..2014
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            2015..2112
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            2113..2274
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            2275..2325
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            2326..2466
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            2467..2669
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
     exon            2670..3725
                     /gene="Ttc7b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccccttccc cggccggcgt tcccgttacg ccgccgagcc gggagccgga gccggagccc
       61 gcggccgcag cgggaggcgg cgcggggccc ggcggcggcg gggcctgcgg ggcctgcggg
      121 cgcgcgccgg gccggccagg gcggccatgg cgaccaggaa ggcgggctcg cggctggaga
      181 cggagatcga gcgctgccgc tccgagtgcc aatgggagcg gatccccgag ctcgtcaagc
      241 agctgtcggc caagcttatc gccaacgatg acatggctga gctgctccta ggggagtcga
      301 aactggagca gcacttgaag gagaagcccc ttcgtcaggg agccagtccc cggggcccca
      361 gaccccagct gaccgaagtg cgcaagcatc tgactgctgc tctggaccga ggaaacctca
      421 agtcagaatt cctacaagag tccaatctgg tcatggccaa gctgaattac gtggaaggag
      481 attataagga agccctgaat atctacgccc gggtgggcct cgacgacctc ccactgatgg
      541 ctgtgcctcc ctacaggctg cggatgattg ctgaagccta cgccaccaaa ggactttgtt
      601 tagagaagct gcctgtttca tcctctacga gtaatctcca tgtggaccgg gagcaggatg
      661 tcatcacctg ctatgagaaa gctggggaca ttgcactctt gtacctgcag gagatagaaa
      721 gggtaatact aactaatatt cagaacagaa gccctaagcc tggccctgct ccccacgatc
      781 aagaactagg ttttttccta gaaacaggac ttcagagagc ccatgtcctc tatttcaaaa
      841 atgggaactt gacaagagga gtcgggagat ttagggagct tctcagagct gtggagacga
      901 ggacaacaca aaacctgcga atgacaatag ccaggcaatt ggcagaaatc ttgttacggg
      961 gcatgtgtga gcagagctac tggaaccctc tggaggagcc tccctgccag tcacctctag
     1021 atgatcctct ccggaaagga gcaaacacta aaacctacac actccctcgc agagcccgcg
     1081 tctactcagg agagaacatt ttttgtcctc aagaaaacac tgaagaggca ctgctgttgc
     1141 tgctcattag tgaatctatg gccaaccgag atgctgtgct gagcaggatt cctgaacaca
     1201 agagtgaccg cctcatcagt ctgcagagcg catctgtggt ctatgattta ctgaccattg
     1261 ctcttgggag aagaggccag tatgagatgc tgtcagagtg cttagaaaga gccatgaagt
     1321 ttgcctttga ggagttccac ctctggtacc aatttgctct gtcgctgatg gctgccggaa
     1381 agtctgcccg tgctgtgaag gtgctaaagg aatgtatccg gctaaagcca gatgatgcca
     1441 ccatcccgct cctggcagcc aagctgtgtg tgggttccct tcactggttg gaagaggctg
     1501 agaagtttgc caaaactgtt gttgatgtgg gagagaaaac gtcagaattc aaggccaaag
     1561 gctacctagc tctggggctc acatatagtc tgcaagccac tgatgcttct ttgcgaggga
     1621 tgcaggaggt cctgcagagg aaggcacttc ttgcacttca gagggcccac agcctgtcac
     1681 ctacagacca ccaagcggct ttctacctgg ctctgcagct cgccatctcc agacagatac
     1741 cagaagctct cggatacgtt cgccaagctc ttcaactcca gggtgatgac gccaactccc
     1801 tgcacctcct cgctctcctg ctgtcagccc agaagcatca ccatgacgct ctcaacatca
     1861 tcgacatggc cctgagcgag tacccagaaa attttatact gctgttttcc aaagtgaagc
     1921 tggagtcgct ctgccggggc ccggatgagg cactgctcac ctgtaagcac atgttacaga
     1981 tatggaaatc ctgctacaac cttaccaatc ccagtgactc tggacgtggg agcagcctct
     2041 tagatagaac catcgctgac agacgacagc ttaacacaat cactttgcca gacttcagcg
     2101 atcctgagac agtgtcagac tcctcctcct cctcttctat ctcaagaacc gaatctcctc
     2161 tccacctgtt tgtgtcttct cctcttcatt ctcatcccaa acctgacatc tttgtgtggc
     2221 cccctgctgc tcattcatta agtgacccag gtccccaccg ggaaccttca ctctgcaact
     2281 ctccagaagc acattttcat ggttttcctt ccctcttttc agttagctcc gtccatgcca
     2341 cgtcagtagc agcctcaaga gtggagcaag cactgtcaga agtggcctcg tctctgcaga
     2401 gcagtgctcc caagcagggg ccactgcacc cctggatgac gctggcacag atctggctcc
     2461 atgcagctga ggtttacatt ggcattggaa aacctgctga agctacggcc tgtacccagg
     2521 aagctgccaa cctcttccca atgtcccaca atgtcctata tatgcggggc caggttgctg
     2581 agcttcgagg aaactttgat gaggctcggc ggtggtacga agaagccttg tccatcagcc
     2641 ctacccatgt gaagagcatg cagcgactgg ccctggtcct tcaccagctg ggccgctaca
     2701 gtctcgctga gaagattctc cgggatgcag tgcaggtgaa ttccacagcc catgaggtct
     2761 ggaacgggct gggtgaggtc ctccaagctc agggcaacga tgccgcagct actgagtgct
     2821 tcctgacagc cttggagctg gaggccagca gccctgccgt gcccttcacc gtcatccccc
     2881 gtgtgctctg agctggaggc cagcagccct gccgtgcccg tcaccgtcat cccccgtgtg
     2941 ctctgagcgg gccacccgcc tcacctgcca cacaggctcg ggatgctccg tgcaggctgc
     3001 cagcggcatc ctgtcaccca gtggacgcat ctgcagtacc gaggccctgg atggatatgt
     3061 gaccggtgtg gatcaacctc accaacccag aatcatagct ctccgctcct acactcattc
     3121 attcttgttt ttgccagacc catgatggtt ctctgaatct actgatgtcc ccaatggatc
     3181 atgtgccata ttcagttagc cgacaccaga gttttaggta aaatgattgc ggacttaatc
     3241 agcaagtgca gaggaagata ttccaggtca gagttgagcg gcagaaggga tcatttttat
     3301 cagtgctgta tgaaagctac cgccctgccc tctgcccgct ccacacctct cctccccctc
     3361 ccttggccca aaaccaaatg tgaattttct gtttcccacc tcagtacccg tccacaccag
     3421 gacaccagct gacagcgtct cggtttcatt gtcaacagct gtaccatgtg gtgaattact
     3481 gtcctcctcc ttagaacaaa gcccgagtct aagaatattt atattttacc aatatatggc
     3541 tgttacaaga gaaggaaata tgagttattt aagtttaact tttttatgtg aattcagagt
     3601 ttatttatcg atggaaatat gtacaaagaa acttcaaatg gaatatttac cgacattcct
     3661 tatacatgac agacacttgg ctaaacagga agatgatgtt aataaaaaaa tgatttttaa
     3721 atgga
//
