LOCUS       NM_001395043            3406 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus tetratricopeptide repeat domain 4 (Ttc4), mRNA.
ACCESSION   NM_001395043 XM_006238519
VERSION     NM_001395043.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3406)
  AUTHORS   Shang,J., Xia,T., Han,Q.Q., Zhao,X., Hu,M.M., Shu,H.B. and Guo,L.
  TITLE     Quantitative Proteomics Identified TTC4 as a TBK1 Interactor and a
            Positive Regulator of SeV-Induced Innate Immunity
  JOURNAL   Proteomics 18 (2) (2018)
   PUBMED   29251827
REFERENCE   2  (bases 1 to 3406)
  AUTHORS   Dmitriev,R.I., Okkelman,I.A., Abdulin,R.A., Shakhparonov,M.I. and
            Pestov,N.B.
  TITLE     Nuclear transport of protein TTC4 depends on the cell cycle
  JOURNAL   Cell Tissue Res 336 (3), 521-527 (2009)
   PUBMED   19390865
REFERENCE   3  (bases 1 to 3406)
  AUTHORS   Crevel,G., Bennett,D. and Cotterill,S.
  TITLE     The human TPR protein TTC4 is a putative Hsp90 co-chaperone which
            interacts with CDC6 and shows alterations in transformed cells
  JOURNAL   PLoS One 3 (3), e0001737 (2008)
   PUBMED   18320024
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3406)
  AUTHORS   Dmitriev,R.I., Korneenko,T.V., Bessonov,A.A., Shakhparonov,M.I.,
            Modyanov,N.N. and Pestov,N.B.
  TITLE     Characterization of hampin/MSL1 as a node in the nuclear
            interactome
  JOURNAL   Biochem Biophys Res Commun 355 (4), 1051-1057 (2007)
   PUBMED   17335777
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On May 27, 2021 this sequence version replaced XM_006238519.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643297.19556.1,
                                           SRR26643429.20180.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760400,
                                           SAMN12840106 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-157               JAXUCZ010000005.1  126690984-126691140 c
            158-275             JAXUCZ010000005.1  126690348-126690465 c
            276-437             JAXUCZ010000005.1  126688761-126688922 c
            438-515             JAXUCZ010000005.1  126687044-126687121 c
            516-640             JAXUCZ010000005.1  126684708-126684832 c
            641-727             JAXUCZ010000005.1  126683543-126683629 c
            728-945             JAXUCZ010000005.1  126681132-126681349 c
            946-1027            JAXUCZ010000005.1  126680649-126680730 c
            1028-1110           JAXUCZ010000005.1  126677799-126677881 c
            1111-3406           JAXUCZ010000005.1  126673535-126675830 c
FEATURES             Location/Qualifiers
     source          1..3406
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q34"
     gene            1..3406
                     /gene="Ttc4"
                     /note="tetratricopeptide repeat domain 4"
                     /db_xref="GeneID:362556"
                     /db_xref="RGD:1308529"
     exon            1..157
                     /gene="Ttc4"
                     /inference="alignment:Splign:2.1.0"
     CDS             47..1207
                     /gene="Ttc4"
                     /codon_start=1
                     /product="tetratricopeptide repeat protein 4"
                     /protein_id="NP_001381972.1"
                     /db_xref="GeneID:362556"
                     /db_xref="RGD:1308529"
                     /translation="MESSDPDPTDDSSMDAFLDKFQSQPYRGGFREDQWEEEFDKIPL
                     FMKKAPSEIDPKEFPDLACLQSIIFDDERSPEEQAKTYKDEGNDYFKEKDYKKAVVSY
                     SEGLKKKCADPDLNAILYTNRAAAQYYLGNFRSALNDVLAAKKLKPDHLKAIIRGALC
                     HLELKHFAEAVNWCDEGLQIDAKEKKLLEMRAKADKLKRMEERDLRKAKLKEKKEQNQ
                     NEALLQAIKARNIRLVSESVGEDEDSASNGLAEMLLHGLSSENPCGARLSIDGQGRLS
                     WPVLFLYPEYAQSDFISAFHEDTRFIDHLMAMFSEAPSWDSEHKYHPDDLEVYFEDED
                     RAELYQVSPESTLLQVLQHPRCSVKALTPAFLVCVGSSPFCKNFLQGKRVHR"
     exon            158..275
                     /gene="Ttc4"
                     /inference="alignment:Splign:2.1.0"
     exon            276..437
                     /gene="Ttc4"
                     /inference="alignment:Splign:2.1.0"
     exon            438..515
                     /gene="Ttc4"
                     /inference="alignment:Splign:2.1.0"
     exon            516..640
                     /gene="Ttc4"
                     /inference="alignment:Splign:2.1.0"
     exon            641..727
                     /gene="Ttc4"
                     /inference="alignment:Splign:2.1.0"
     exon            728..945
                     /gene="Ttc4"
                     /inference="alignment:Splign:2.1.0"
     exon            946..1027
                     /gene="Ttc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1028..1110
                     /gene="Ttc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1111..3406
                     /gene="Ttc4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caggtttctt ggcccccaga ttgaagtgcc gaagttgcga gctgccatgg agagttctga
       61 tcctgaccct acagatgaca gttccatgga cgcgttcctg gacaagttcc agagccagcc
      121 ttaccgcggc ggcttccgcg aggaccagtg ggaggaggaa tttgacaaga tccccctatt
      181 tatgaaaaaa gcgccatcag aaattgatcc caaggagttt cctgacttgg cttgcctcca
      241 atcgattatt tttgatgatg agcgatctcc agaagagcaa gccaagacct ataaagatga
      301 gggcaatgac tactttaaag aaaaagacta taagaaagct gtggtttcct acagtgaagg
      361 actgaagaag aagtgtgcag accctgatct gaatgccatc ctgtatacca accgggcagc
      421 agcacagtac tatctcggca atttccgctc tgctctcaat gacgtgctgg ctgccaagaa
      481 gctaaagcct gatcacctga aagccatcat acgaggtgcc ctgtgccatc ttgaactgaa
      541 acactttgct gaggctgtga actggtgtga tgagggacta cagattgatg ccaaagagaa
      601 gaaacttcta gaaatgaggg caaaagcaga caagctaaag aggatggagg agcgggatct
      661 gaggaaagca aagttgaaag aaaagaagga acaaaatcag aatgaggctc tgctccaggc
      721 catcaaggct aggaacatca ggcttgtctc tgaatcagtc ggtgaggatg aagattcagc
      781 ctccaatggt ctagccgaga tgctcctgca tgggctcagc tctgagaacc cctgtggagc
      841 caggctcagt atagatggcc aaggcaggct gagctggcct gttctgttcc tgtaccccga
      901 gtatgcacag tctgacttca tctctgcttt tcacgaggac accaggttta ttgaccatct
      961 aatggcgatg tttagtgaag cgccctcctg ggactcagag cacaagtacc acccagatga
     1021 tctggaggtc tacttcgagg atgaggacag ggcagaacta taccaggtgt cccctgagag
     1081 caccctgctg caggtgctgc agcaccccag gtgctccgtg aaggccctta ccccggcatt
     1141 cctggtctgt gtaggatcct ctcctttctg taagaatttt ctccagggga aaagggtgca
     1201 caggtaacct aggaacagac cctggggtct tgtccctcat cttcctctgc ctggagtctg
     1261 cacactgaat catctggcct agagtccagc actctgtccc cagggacagt ggttcctaac
     1321 ctcttgttgg ggaagaagct gctggactcc ctgaccctac ccctgtctgg ctgagtgctg
     1381 cgctccagct gggcctcagc ctcctcacat tcacagctct gccctggcca gtccatcttt
     1441 ggagtccatc tctgaagaaa gcatccactg caattaccag aatagctggc cttggtaact
     1501 ccctggcccc tagactatct caggatgcag tgacagtctc aaccattgta gcattgggca
     1561 catacagaag gcacagctcc aagggagtaa accagcgctg cacagtactc ttaaggcctt
     1621 agggcttgaa agactggtag ttgcttcacc agcatgagaa aagctaaggg atgctgtgga
     1681 tgccgtgaga cgactggagc catgaagcca catcctgttt ctgcgttgac tgtatgaact
     1741 gggatcctca ggactactca gagccctact ggtttctctg accagtggag ttgcagtatg
     1801 agaactgcaa cagacctggc ggtagcccaa gtgcttcctc cattcctcag ctccagttat
     1861 gtccttgcct cagcaaaaga atgctgaatg gaggtgtgca ccactgtgcc tggctagcat
     1921 ttcatgcctt ttgacctagc ctttgcctgt caccggctgt ttttgtcttg tgctgttctc
     1981 tgcgtcctag aggttgtgtg cattcttagc tgcagctgag tggcttcctg cagtgtccac
     2041 gccatctccc aaggggagca tacttctcat tgcccatgca agggctatga aacagggctt
     2101 gagccacatc tggcagcagc ttgaggtgtc attgggcagt ggtttgcaag taggcttgtg
     2161 tcctttcccc tttaccatga ggcgccattt ctcaaatagg agcatccccg tcacctgggt
     2221 gtctgaagaa agctcacagc agctggccta aagccaccgt ttgtaacgtg agtggcagat
     2281 gtttgtgtag taaacactga gatttggggg attgtttgtc actataggaa aactaataca
     2341 gcattaaagt gaaaccagct gacggccttc agatgggcta atttgggatc ttgtgttgat
     2401 tgtatccttg tttctggaag agaaattgtt tttagggaga ccagtgcagc tttctttccc
     2461 cgggcaggtc cctgtaacac acacagtggt ttgcaaacac tgcagacatt ctctcctcgc
     2521 tagagacttt cccctgactt cctttgtaag aactcaaagt ctatgtgagg ggcttaagag
     2581 tcagctacaa tctggcagac actgcaggat cccagaagca gatgtctgta gctacctcac
     2641 tgtcatggac aaatcatgtt ctactgcgcc ttcctaccgt ctaattggag atctaaccca
     2701 gcctctcact tggtgaggct gaggtgaggt ggtgggtaag agcaaggtgc aaactgaaat
     2761 gtacctggca ggtgttgtga ttgtttcacc ctgggaccct gcccttccca tcagacagcg
     2821 tctgctgtgc ttctagtctt tgaccctctg gagtcatcag cttagatgcc acgggggaga
     2881 gaatgtctta gttacttatt tgttgctgtt gagacactat gacaacccaa cttatagaag
     2941 agtttattgg ggcccttggt accagcaggt gagttacaac ccaagaccat cgtggcagag
     3001 attgtggtag caggaaggca ggtatggtac tggagcagta gctgaaaact cacatcttgg
     3061 gacaaccaca aggtagagaa cgagttaact ggcaatggct gggcttttga aactataaaa
     3121 caccagtgac actgatggtt tgttgcttgg cccagggagt ggagctatta ggaggtgtgt
     3181 gtggccttgt tagagtaggt gtgtcactgt gggtatgagt tataagaccc tcatcctagc
     3241 tgcctggaag tcagtattct gctggcagcc ttcagatgaa gatgtagaac tctcagctcc
     3301 tcctgcacca tgcctgcctg gatgctgctg tgctcctgcc ttgatgataa tggactgaaa
     3361 ctctgaacct ataagccagc cccaattaaa tgttgtcctt ataaga
//
