LOCUS       XM_039088472            6463 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus tetratricopeptide repeat domain 3
            (Ttc3), transcript variant X13, mRNA.
ACCESSION   XM_039088472
VERSION     XM_039088472.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051346.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6463
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6463
                     /gene="Ttc3"
                     /note="tetratricopeptide repeat domain 3; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 15 mRNAs, 253 ESTs, 2 long SRA reads, 1 Protein, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 179 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:360702"
                     /db_xref="RGD:1308654"
     CDS             253..5268
                     /gene="Ttc3"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase TTC3 isoform X11"
                     /protein_id="XP_038944400.1"
                     /db_xref="GeneID:360702"
                     /db_xref="RGD:1308654"
                     /translation="MLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHIKLQKQIEDLQ
                     GRTSNRNPIKAFYESRAYIPRNSSAPAFRTSLNFVETERGFRKTKYRMANGGGHQNQK
                     VADEALKGDDCDCHPEFLPPPSQPPRHKGKQKSRNNESEKPSSNSQVTLQVDLKSILE
                     KQFSKSSRAAHQDFANIMKMLRSLIQDGYTALLEQRCRSAAQAFTELLNGLDPQKIKQ
                     LNLAMINYVLVVYGLAVSLLGIGRPEELSEAENQFKRIIEHYPNEGLDCLAYCGIGKV
                     YLKKNRFLEALNHFEKAKTLICRLPGILTWPTSNVIIEESKPEKVKVMLEKFVEECKF
                     PPVPDAVCCYQKCRGFSKIQIYLTDPDFKGFIRISCCQYCKVEFHMNCWKKLKTTTFN
                     DKIDKDFLQGICLTPDCEGIISKIIIFSSGGQVKCEFEHKVVKEKAPSRPVLKQKCSS
                     LEKLRLKEDKKLKRKIQKQEAKKLAQERMEEDLRESNPPKPEEPEETVESAQSCQFLD
                     DRILQCIKQNADKIKSVVLNTSTLLKELLSWKVLSTEDYTTCFSSKNFVHEAVDYVIG
                     HLIQEKNRVKTRIFLHVLSELKELDPKLAPWIQRLNSFGLDATGPFFTRYGASLKELD
                     FNIVTFLWSEKYGHKLGSIEGKQLDYFCEPASVMEARCLIWLLEEHRDKFPALHSALD
                     EFFDIMDSRCTVLRKQDSDEMPFGCIKVKNKGKKKKPKDSKPMLVGSGTASVTPSSET
                     VTPEDHNRRNSDSAGPFAVPDHLRQDVEEFEALYDQHSSEYVVRNKKLWDINPKQKCS
                     TLYDYFSQLLEEHGPLDMSDRMFSEEYEFFPEETRQILEKAGGLKSFLLGCPRFVVID
                     NCIALKKVASRLKKKRKKKNIKTKVEEISKTGEYLRVKLPLNPTAREFQPDVKSEAAA
                     EDVTSIPGPADSSAPAAEDLKPQLDSDSSSGSASEDSRLEVVSPDLPTPLCEDASPSP
                     TPAPEDAKPTYWTQSHLVTGFCTYLPFQGFGIAQSRPAYINMVPSLSQFTSIYTPLAN
                     ISSEYPMPRSMPVVPSFVASERADGNAAAYFESHRLNTENASDDHTASETQILEGPLG
                     MCVKSQSSTADARTALSEPEGNSRHSGSSDSLWEASLENVSGITDVPPAPSVAIQVSR
                     SLIHQEVNTEPYAPFERQQGDLSQKEKECHLLREQLQVACEECEQMELRSSQETRDLE
                     EKLQRHAEENKISKTELDWFLQDLDREIKKWHQEKKEIQERLKALKKKIKKVINTSDM
                     SAQKNDGLDKECESQPDQSLGISSALTDEKAKVEESVRKGKELYEESQQRAVAAEVSV
                     LENWKEREVCKLQGVATQAEACLKSLKLMNSDSAAYPDVECDILSWETFLSTVTEEIE
                     NTKCQFEEQIKAIKSGSRLSDLSSVQVSELLFPACSMIHPQLLSESSRHEDHGLVACV
                     DSMTGAVLNDPYVGPDSGCSEEVPELSLGSPTHHPEGAQQLEVKKASQVSPSEQNPEA
                     DEKPSGQATRSSQSQKNPFNSIIEHLSVIFPCYASSELSGFIKKVRNKSKNSFSGLSI
                     EEIVERVTEHIVEEQKKKKPNPGKDKKTSEAHPAASVSKSSPSPPLAAAGPSAKTKGQ
                     KKDDVPAPDGNSCQICHEIFKSKNMRVLKCGHKFHKGCFKQWLKGQSTCPTCGSSDLL
                     SEE"
ORIGIN      
        1 gtggagggcc ggaggcgtcg gcagcccgcg tccgaggctc gcgggctgcg ggcccgggtg
       61 agtgcagacc ctgcgcgcgg cggggctccc ggaagcgtct gcgcatcccg ccgcagccga
      121 gatgcctggg catcggggcg ctccacacct ccctccgtgg gtgtgtgaaa tgcacttagt
      181 gatggaaaga gggccattgt tttgaagaac acctggccga agggtcatta tcgttattgt
      241 gatgctcttt ctatgctggg ggaatatgac tgggccctgc aagcaaacat aaaagctcaa
      301 aaactctgta aaaatgaccc tgagggaatc aaggatctaa ttcagcagca tataaagtta
      361 caaaaacaaa tagaagacct acaaggtcgg acatcaaata ggaatccaat taaagctttt
      421 tatgaaagca gggcttacat acctagaaac tcatcagcac ctgcttttag aacatcactt
      481 aactttgtgg aaacagaaag aggtttcagg aaaactaagt acagaatggc aaatggcggt
      541 ggccatcaga atcaaaaggt ggcagatgag gctttgaagg gggacgattg tgactgtcat
      601 cctgaatttc tgccacctcc aagtcagcct ccaagacata aaggaaaaca aaagtcacgg
      661 aacaatgaat cagaaaagcc cagttctaat tctcaagtga ctttacaagt agatttgaaa
      721 agcattttgg agaaacaatt ttcaaaatct tccagagctg cacaccagga ttttgctaac
      781 atcatgaaaa tgttaagaag cttgattcag gatgggtaca cggccttgtt ggagcagcgc
      841 tgccgcagtg ctgcccaggc ctttacagag ttactcaatg gcttagatcc tcagaaaata
      901 aagcaattga acctggccat gattaattat gtattagtag tctatggact tgctgtttct
      961 ctccttggaa taggacgacc tgaggaactg tctgaagccg aaaaccagtt taagaggatc
     1021 atcgaacact atcccaatga ggggcttgac tgcttggcct actgtggaat aggaaaagta
     1081 tatttgaaaa aaaacagatt tctcgaagct cttaatcact ttgaaaaagc aaaaacttta
     1141 atttgtcgtc tccctggaat tctaacttgg cccacaagta atgtgattat tgaagaatct
     1201 aagccagaaa aggtcaaggt gatgttagag aagtttgttg aagaatgcaa gtttcctcct
     1261 gtgccggatg ctgtttgttg ctatcagaag tgccgtgggt tttccaaaat ccagatttac
     1321 ctaactgacc cagacttcaa gggttttata cgaattagct gttgccaata ctgtaaagta
     1381 gaatttcaca tgaactgctg gaaaaagtta aaaacaacaa cttttaatga taaaattgac
     1441 aaggattttc tacaaggaat ttgtctcacc cctgactgtg aaggaatcat ttctaagatt
     1501 atcatcttta gcagtggtgg ccaagttaaa tgtgaatttg aacacaaggt cgtaaaagaa
     1561 aaggctcctt caagacctgt tctgaaacag aaatgttcta gtctagagaa gttaagactg
     1621 aaagaagaca aaaaattgaa gagaaagatc caaaaacaag aggcaaaaaa gttggcacaa
     1681 gaaagaatgg aagaggactt aagagaaagt aatccaccta aacctgaaga gccggaagaa
     1741 actgtagaaa gcgctcagag ttgtcagttt cttgatgaca gaatccttca gtgcataaag
     1801 cagaatgctg acaagattaa atctgttgtg ttgaacactt ccacgcttct caaagagttg
     1861 ctgtcttgga aggttctgag cacagaagac tacacaacat gtttttctag caaaaatttt
     1921 gttcatgaag cagtggacta tgttatcggt cacttgattc aagaaaagaa cagagtaaag
     1981 acacggatat ttctgcatgt tttgagtgag cttaaagagt tagaccccaa gttagctccc
     2041 tggatccaga gactgaatag ctttggctta gatgccacag gacccttttt tactcgctat
     2101 ggagcatctc tcaaagagct tgattttaac attgtgactt tcctttggag tgagaaatat
     2161 ggccataaac taggttctat agaaggaaag caacttgatt acttctgtga gccagcatca
     2221 gtaatggaag cacgctgctt aatatggctg ctggaagagc acagggacaa gttccccgcc
     2281 ttgcacagtg ctttagacga gttctttgat ataatggaca gccgatgcac tgtgctaagg
     2341 aagcaagaca gtgatgaaat gccgtttggt tgtatcaagg taaaaaacaa aggcaagaaa
     2401 aagaagccaa aagattcaaa gccgatgtta gtgggatctg gaacagcatc agtaacacca
     2461 agtagtgaga ctgtcactcc agaagaccat aacaggcgca attcagattc tgcaggacca
     2521 tttgcagtgc ctgaccacct tcggcaagat gtggaagagt tcgaagctct ttacgaccag
     2581 cacagcagcg agtatgttgt ccgaaataag aagctgtggg atattaaccc caaacagaaa
     2641 tgttcaactc tgtatgatta cttctctcag ttgctggaag agcacggccc cttggatatg
     2701 agtgatagga tgttctctga ggaatatgag ttcttccctg aagaaactcg ccagatactg
     2761 gagaaggcag gagggctgaa gtcgttcctc ctgggctgtc ctcgatttgt tgtgattgac
     2821 aactgcattg cattgaaaaa agttgcctca agactcaaga aaaaaagaaa gaagaaaaac
     2881 attaaaacta aagttgaaga aatttcaaaa acaggagaat atttacgagt taaacttcca
     2941 ctaaatccaa ctgctaggga atttcagcca gatgtaaagt ctgaagcagc agctgaggat
     3001 gtgacgtcca taccaggacc tgctgactct tcagcaccag ctgctgagga tctgaagccc
     3061 cagctggact ctgatagctc ttctgggtca gcttcagagg acagcagact ggaagttgtc
     3121 tctcctgact tgcctacacc actctgtgag gatgcttctc cttcccccac accagctcct
     3181 gaagatgcca aaccaactta ctggactcag tcacacctgg tcacaggatt ctgcacatac
     3241 cttccttttc aaggatttgg catcgcccag tctcggccag cgtacattaa catggtacca
     3301 agcctgtccc agttcactag catttacacg cctttggcca acatttcttc tgagtatcca
     3361 atgccaagat ccatgccagt ggtaccatct tttgtagcca gcgagagagc agacggaaat
     3421 gccgctgcat actttgagag tcatcgtctg aacactgaga acgcctctga tgaccacact
     3481 gcctctgaaa cacagatcct ggagggtcct ttgggaatgt gcgtaaagtc ccagagcagc
     3541 acagctgatg cccggacagc tctgagtgag cctgaaggaa acagcagaca cagtgggagc
     3601 tctgacagcc tgtgggaagc ttctctagaa aacgtcagtg gaataacaga tgttccacca
     3661 gctccgtcgg ttgccataca ggtgtccagg agcttgatac atcaggaagt caatactgag
     3721 ccatatgcac cttttgaaag acaacagggg gacctttccc agaaggagaa ggagtgccac
     3781 ctgctcagag agcagcttca ggtggcctgt gaggagtgtg agcagatgga actcaggagc
     3841 tcacaggaga ccagggacct ggaggagaag ctgcaaaggc acgcggagga gaacaagatt
     3901 tcaaagacgg aattagactg gttcctccaa gatttggaca gagagattaa aaagtggcat
     3961 caagagaaaa aagaaatcca agaaaggtta aaagccctga agaaaaaaat taaaaaggtt
     4021 atcaatacca gtgacatgtc tgcacagaaa aatgatggat tagataaaga atgtgaatca
     4081 cagccggacc agtcccttgg aatcagcagt gcactcacag atgagaaggc aaaagtagag
     4141 gagtctgtca ggaaagggaa ggagctctat gaagagagtc agcagagagc tgtggctgca
     4201 gaggtgtctg tgcttgagaa ctggaaggag cgagaagtct gtaaactgca gggcgtggca
     4261 acacaagcag aagcctgtct taaaagcctg aagctgatga acagtgactc tgcagcatat
     4321 cctgatgtgg agtgtgatat actttcgtgg gaaacattcc tttctactgt aacagaagaa
     4381 attgagaaca caaagtgtca gtttgaagag caaattaagg ctattaagag tggctctcga
     4441 ctcagtgacc tttccagtgt acaggtttct gagcttttat ttcctgcttg ttcaatgatt
     4501 catcctcagt tactctctga gtcttcaaga catgaggatc acgggctagt ggcttgtgta
     4561 gacagcatga ctggagcagt cctcaacgat ccgtatgtag ggcctgatag tggctgctca
     4621 gaggaagttc cagaactgtc actgggatcg cctacccatc atccagaagg tgctcaacag
     4681 ttagaggtta agaaggctag ccaggtgtct ccatcagaac agaaccctga ggctgatgaa
     4741 aaaccatctg ggcaggccac gaggtcaagc cagtctcaaa aaaatccttt caacagtatt
     4801 attgaacacc tgtcagtgat attcccatgt tatgccagct ccgagctttc tggttttatt
     4861 aaaaaagtta gaaacaaaag caagaactca ttctcgggat taagtattga ggagattgtt
     4921 gagagagtaa cagaacacat tgtcgaggaa cagaagaaga agaagccaaa tccaggaaag
     4981 gacaagaaga catctgaggc tcatcccgct gcctctgtgt ccaagtcttc cccgagtcca
     5041 cccttggcag ctgctggacc atcagctaaa accaaaggcc agaaaaaaga tgatgtccct
     5101 gcaccagatg gaaattcctg tcaaatatgc catgaaatat tcaagtcaaa aaacatgcgt
     5161 gtgctaaaat gtgggcacaa gtttcacaaa gggtgcttta agcaatggct gaaagggcag
     5221 agcacgtgcc ccacctgtgg cagcagtgac ctgctgtcag aagagtaacc tgttgcgcca
     5281 ccatcacagt cccagcccag aagaagatgg gaccctcctt cctgttgctg taggtagtca
     5341 ctcctcacta atgcaccatg cacttcatga gttaaagaac aacaatgtcc tgttgccagt
     5401 gtaaagacag caaacatgga cactctcgca ctgtgcatca caaagctaac aaatcgaaat
     5461 cttgaatgca gtctgtccta agtccaggca agtgacagcc atgtgtgtct gcagtgctgt
     5521 gtcaccacgt cctgcattgt tggagctgct gcagggacac tgagatgagc aggttctttg
     5581 gaaagaactg ttgtgctcct caaagcagtg ttcagatttt aaaggttctt agcctcctca
     5641 gttccttatg tggaactgta ggatcccctt cataaatttt taaagtgctt atgtgatcca
     5701 attggtctac attttggtaa tcaagtataa aatacttttt aaattagtat cagctaagaa
     5761 ttttttttac cctgggaaga tgctgtctgt tcacaggagt cccacacttg acacttacac
     5821 taaggttacc atgtaagtct catgagtcag ccagtgcttg gaaaggcccg gctgaatgca
     5881 ggacaaagtg ccgagcacag gacagtcact ctcactctcc ttccttattc ttcctccgga
     5941 agggaaatgt actacagtcc tgacgtgttg gtgttaacat tgttctgttt gacttttgtg
     6001 taaagtaatg catgcaatct tgtaatgtgg cctgaaaaac aagctaactg tattagaaac
     6061 tattcaaaaa ctaggtattt tttagtgacc tgtaggcagt ggcaaataca gacacgtgaa
     6121 cccaagatac attacatttc tttcaaacac aaagaaacaa aaatgtttcc caacgtgttc
     6181 tctgctgccc tggagatgct gtcaccttcg acctgtgtcc atgtgatttg tggtgtctta
     6241 gtgacctagt ctgtagctta ctctttattc tgagacactg tccctggtgt acgtgctgta
     6301 acagtgaatg caggccatgc taaagtgcgc gcacagcagc ttatggtacc cgtcgggcac
     6361 agaggcgtag ctattgagac agtgagctgt gcttcacgtc agcctgtgaa catgccttac
     6421 acttgtccag tacctgtcaa taaagagcat tctcaaagat caa
//
