LOCUS       XM_039088469            6688 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus tetratricopeptide repeat domain 3
            (Ttc3), transcript variant X10, mRNA.
ACCESSION   XM_039088469
VERSION     XM_039088469.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051346.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6688
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6688
                     /gene="Ttc3"
                     /note="tetratricopeptide repeat domain 3; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 15 mRNAs, 252 ESTs, 2 long SRA reads, 1 Protein, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 20 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:360702"
                     /db_xref="RGD:1308654"
     CDS             1..5493
                     /gene="Ttc3"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase TTC3 isoform X8"
                     /protein_id="XP_038944397.1"
                     /db_xref="GeneID:360702"
                     /db_xref="RGD:1308654"
                     /translation="MFYGHMRIAKILAMEDALNWIKYTGDVTILPKLGSVDSGWPMLS
                     IFFTEYKYHITRVVTENCNLLEEFRRHSCMQCVKQGELMKMRGNEEFAKEKFEIAVIY
                     YTRAIEYRPENHLLYGNRALCFLRMGQFRNALSDGKRAIVLKNTWPKGHYRYCDALSM
                     LGEYDWALQANIKAQKLCKNDPEGIKDLIQQHIKLQKQIEDLQGRTSNRNPIKAFYES
                     RAYIPRNSSAPAFRTSLNFVETERGFRKTKYRMANGGGHQNQKVADEALKGDDCDCHP
                     EFLPPPSQPPRHKGKQKSRNNESEKPSSNSQVTLQVDLKSILEKQFSKSSRAAHQDFA
                     NIMKMLRSLIQDGYTALLEQRCRSAAQAFTELLNGLDPQKIKQLNLAMINYVLVVYGL
                     AVSLLGIGRPEELSEAENQFKRIIEHYPNEGLDCLAYCGIGKVYLKKNRFLEALNHFE
                     KAKTLICRLPGILTWPTSNVIIEESKPEKVKVMLEKFVEECKFPPVPDAVCCYQKCRG
                     FSKIQIYLTDPDFKGFIRISCCQYCKVEFHMNCWKKLKTTTFNDKIDKDFLQGICLTP
                     DCEGIISKIIIFSSGGQVKCEFEHKVVKEKAPSRPVLKQKCSSLEKLRLKEDKKLKRK
                     IQKQEAKKLAQERMEEDLRESNPPKPEEPEETVESAQSCQFLDDRILQCIKQNADKIK
                     SVVLNTSTLLKELLSWKVLSTEDYTTCFSSKNFVHEAVDYVIGHLIQEKNRVKTRIFL
                     HVLSELKELDPKLAPWIQRLNSFGLDATGPFFTRYGASLKELDFNIVTFLWSEKYGHK
                     LGSIEGKQLDYFCEPASVMEARCLIWLLEEHRDKFPALHSALDEFFDIMDSRCTVLRK
                     QDSDEMPFGCIKVKNKGKKKKPKDSKPMLVGSGTASVTPSSETVTPEDHNRRNSDSAG
                     PFAVPDHLRQDVEEFEALYDQHSSEYVVRNKKLWDINPKQKCSTLYDYFSQLLEEHGP
                     LDMSDRMFSEEYEFFPEETRQILEKAGGLKSFLLGCPRFVVIDNCIALKKVASRLKKK
                     RKKKNIKTKVEEISKTGEYLRVKLPLNPTAREFQPDVKSEAAAEDVTSIPGPADSSAP
                     AAEDLKPQLDSDSSSGSASEDSRLEVVSPDLPTPLCEDASPSPTPAPEDAKPTYWTQS
                     HLVTGFCTYLPFQGFGIAQSRPAYINMVPSLSQFTSIYTPLANISSEYPMPRSMPVVP
                     SFVASERADGNAAAYFESHRLNTENASDDHTASETQILEGPLGMCVKSQSSTADARTA
                     LSEPEGNSRHSGSSDSLWEASLENVSGITDVPPAPSVAIQVSRSLIHQEVNTEPYAPF
                     ERQQGDLSQKEKECHLLREQLQVACEECEQMELRSSQETRDLEEKLQRHAEENKISKT
                     ELDWFLQDLDREIKKWHQEKKEIQERLKALKKKIKKVINTSDMSAQKNDGLDKECESQ
                     PDQSLGISSALTDEKAKVEESVRKGKELYEESQQRAVAAEVSVLENWKEREVCKLQGV
                     ATQAEACLKSLKLMNSDSAAYPDVECDILSWETFLSTVTEEIENTKCQFEEQIKAIKS
                     GSRLSDLSSVQVSELLFPACSMIHPQLLSESSRHEDHGLVACVDSMTGAVLNDPYVGP
                     DSGCSEEVPELSLGSPTHHPEGAQQLEVKKASQVSPSEQNPEADEKPSGQATRSSQSQ
                     KNPFNSIIEHLSVIFPCYASSELSGFIKKVRNKSKNSFSGLSIEEIVERVTEHIVEEQ
                     KKKKPNPGKDKKTSEAHPAASVSKSSPSPPLAAAGPSAKTKGQKKDDVPAPDGNSCQI
                     CHEIFKSKNMRVLKCGHKFHKGCFKQWLKGQSTCPTCGSSDLLSEE"
ORIGIN      
        1 atgttctacg gtcacatgag gatagctaaa atcttggcaa tggaagatgc tttaaattgg
       61 ataaaataca cgggtgatgt aacaattcta cctaaattag gatcagttga cagtggctgg
      121 cccatgttaa gtattttctt tactgaatat aagtaccata ttactagagt tgtaactgaa
      181 aattgcaact tgctagaaga atttagaagg catagttgca tgcagtgtgt gaagcaagga
      241 gaactcatga aaatgagagg aaatgaagag tttgcaaagg aaaagtttga aatagctgtt
      301 atttattaca ccagagccat tgaatataga cctgaaaacc atcttcttta tggtaaccga
      361 gctctctgtt ttcttcgtat ggggcagttt agaaatgcac ttagtgatgg aaagagggcc
      421 attgttttga agaacacctg gccgaagggt cattatcgtt attgtgatgc tctttctatg
      481 ctgggggaat atgactgggc cctgcaagca aacataaaag ctcaaaaact ctgtaaaaat
      541 gaccctgagg gaatcaagga tctaattcag cagcatataa agttacaaaa acaaatagaa
      601 gacctacaag gtcggacatc aaataggaat ccaattaaag ctttttatga aagcagggct
      661 tacataccta gaaactcatc agcacctgct tttagaacat cacttaactt tgtggaaaca
      721 gaaagaggtt tcaggaaaac taagtacaga atggcaaatg gcggtggcca tcagaatcaa
      781 aaggtggcag atgaggcttt gaagggggac gattgtgact gtcatcctga atttctgcca
      841 cctccaagtc agcctccaag acataaagga aaacaaaagt cacggaacaa tgaatcagaa
      901 aagcccagtt ctaattctca agtgacttta caagtagatt tgaaaagcat tttggagaaa
      961 caattttcaa aatcttccag agctgcacac caggattttg ctaacatcat gaaaatgtta
     1021 agaagcttga ttcaggatgg gtacacggcc ttgttggagc agcgctgccg cagtgctgcc
     1081 caggccttta cagagttact caatggctta gatcctcaga aaataaagca attgaacctg
     1141 gccatgatta attatgtatt agtagtctat ggacttgctg tttctctcct tggaatagga
     1201 cgacctgagg aactgtctga agccgaaaac cagtttaaga ggatcatcga acactatccc
     1261 aatgaggggc ttgactgctt ggcctactgt ggaataggaa aagtatattt gaaaaaaaac
     1321 agatttctcg aagctcttaa tcactttgaa aaagcaaaaa ctttaatttg tcgtctccct
     1381 ggaattctaa cttggcccac aagtaatgtg attattgaag aatctaagcc agaaaaggtc
     1441 aaggtgatgt tagagaagtt tgttgaagaa tgcaagtttc ctcctgtgcc ggatgctgtt
     1501 tgttgctatc agaagtgccg tgggttttcc aaaatccaga tttacctaac tgacccagac
     1561 ttcaagggtt ttatacgaat tagctgttgc caatactgta aagtagaatt tcacatgaac
     1621 tgctggaaaa agttaaaaac aacaactttt aatgataaaa ttgacaagga ttttctacaa
     1681 ggaatttgtc tcacccctga ctgtgaagga atcatttcta agattatcat ctttagcagt
     1741 ggtggccaag ttaaatgtga atttgaacac aaggtcgtaa aagaaaaggc tccttcaaga
     1801 cctgttctga aacagaaatg ttctagtcta gagaagttaa gactgaaaga agacaaaaaa
     1861 ttgaagagaa agatccaaaa acaagaggca aaaaagttgg cacaagaaag aatggaagag
     1921 gacttaagag aaagtaatcc acctaaacct gaagagccgg aagaaactgt agaaagcgct
     1981 cagagttgtc agtttcttga tgacagaatc cttcagtgca taaagcagaa tgctgacaag
     2041 attaaatctg ttgtgttgaa cacttccacg cttctcaaag agttgctgtc ttggaaggtt
     2101 ctgagcacag aagactacac aacatgtttt tctagcaaaa attttgttca tgaagcagtg
     2161 gactatgtta tcggtcactt gattcaagaa aagaacagag taaagacacg gatatttctg
     2221 catgttttga gtgagcttaa agagttagac cccaagttag ctccctggat ccagagactg
     2281 aatagctttg gcttagatgc cacaggaccc ttttttactc gctatggagc atctctcaaa
     2341 gagcttgatt ttaacattgt gactttcctt tggagtgaga aatatggcca taaactaggt
     2401 tctatagaag gaaagcaact tgattacttc tgtgagccag catcagtaat ggaagcacgc
     2461 tgcttaatat ggctgctgga agagcacagg gacaagttcc ccgccttgca cagtgcttta
     2521 gacgagttct ttgatataat ggacagccga tgcactgtgc taaggaagca agacagtgat
     2581 gaaatgccgt ttggttgtat caaggtaaaa aacaaaggca agaaaaagaa gccaaaagat
     2641 tcaaagccga tgttagtggg atctggaaca gcatcagtaa caccaagtag tgagactgtc
     2701 actccagaag accataacag gcgcaattca gattctgcag gaccatttgc agtgcctgac
     2761 caccttcggc aagatgtgga agagttcgaa gctctttacg accagcacag cagcgagtat
     2821 gttgtccgaa ataagaagct gtgggatatt aaccccaaac agaaatgttc aactctgtat
     2881 gattacttct ctcagttgct ggaagagcac ggccccttgg atatgagtga taggatgttc
     2941 tctgaggaat atgagttctt ccctgaagaa actcgccaga tactggagaa ggcaggaggg
     3001 ctgaagtcgt tcctcctggg ctgtcctcga tttgttgtga ttgacaactg cattgcattg
     3061 aaaaaagttg cctcaagact caagaaaaaa agaaagaaga aaaacattaa aactaaagtt
     3121 gaagaaattt caaaaacagg agaatattta cgagttaaac ttccactaaa tccaactgct
     3181 agggaatttc agccagatgt aaagtctgaa gcagcagctg aggatgtgac gtccatacca
     3241 ggacctgctg actcttcagc accagctgct gaggatctga agccccagct ggactctgat
     3301 agctcttctg ggtcagcttc agaggacagc agactggaag ttgtctctcc tgacttgcct
     3361 acaccactct gtgaggatgc ttctccttcc cccacaccag ctcctgaaga tgccaaacca
     3421 acttactgga ctcagtcaca cctggtcaca ggattctgca cataccttcc ttttcaagga
     3481 tttggcatcg cccagtctcg gccagcgtac attaacatgg taccaagcct gtcccagttc
     3541 actagcattt acacgccttt ggccaacatt tcttctgagt atccaatgcc aagatccatg
     3601 ccagtggtac catcttttgt agccagcgag agagcagacg gaaatgccgc tgcatacttt
     3661 gagagtcatc gtctgaacac tgagaacgcc tctgatgacc acactgcctc tgaaacacag
     3721 atcctggagg gtcctttggg aatgtgcgta aagtcccaga gcagcacagc tgatgcccgg
     3781 acagctctga gtgagcctga aggaaacagc agacacagtg ggagctctga cagcctgtgg
     3841 gaagcttctc tagaaaacgt cagtggaata acagatgttc caccagctcc gtcggttgcc
     3901 atacaggtgt ccaggagctt gatacatcag gaagtcaata ctgagccata tgcacctttt
     3961 gaaagacaac agggggacct ttcccagaag gagaaggagt gccacctgct cagagagcag
     4021 cttcaggtgg cctgtgagga gtgtgagcag atggaactca ggagctcaca ggagaccagg
     4081 gacctggagg agaagctgca aaggcacgcg gaggagaaca agatttcaaa gacggaatta
     4141 gactggttcc tccaagattt ggacagagag attaaaaagt ggcatcaaga gaaaaaagaa
     4201 atccaagaaa ggttaaaagc cctgaagaaa aaaattaaaa aggttatcaa taccagtgac
     4261 atgtctgcac agaaaaatga tggattagat aaagaatgtg aatcacagcc ggaccagtcc
     4321 cttggaatca gcagtgcact cacagatgag aaggcaaaag tagaggagtc tgtcaggaaa
     4381 gggaaggagc tctatgaaga gagtcagcag agagctgtgg ctgcagaggt gtctgtgctt
     4441 gagaactgga aggagcgaga agtctgtaaa ctgcagggcg tggcaacaca agcagaagcc
     4501 tgtcttaaaa gcctgaagct gatgaacagt gactctgcag catatcctga tgtggagtgt
     4561 gatatacttt cgtgggaaac attcctttct actgtaacag aagaaattga gaacacaaag
     4621 tgtcagtttg aagagcaaat taaggctatt aagagtggct ctcgactcag tgacctttcc
     4681 agtgtacagg tttctgagct tttatttcct gcttgttcaa tgattcatcc tcagttactc
     4741 tctgagtctt caagacatga ggatcacggg ctagtggctt gtgtagacag catgactgga
     4801 gcagtcctca acgatccgta tgtagggcct gatagtggct gctcagagga agttccagaa
     4861 ctgtcactgg gatcgcctac ccatcatcca gaaggtgctc aacagttaga ggttaagaag
     4921 gctagccagg tgtctccatc agaacagaac cctgaggctg atgaaaaacc atctgggcag
     4981 gccacgaggt caagccagtc tcaaaaaaat cctttcaaca gtattattga acacctgtca
     5041 gtgatattcc catgttatgc cagctccgag ctttctggtt ttattaaaaa agttagaaac
     5101 aaaagcaaga actcattctc gggattaagt attgaggaga ttgttgagag agtaacagaa
     5161 cacattgtcg aggaacagaa gaagaagaag ccaaatccag gaaaggacaa gaagacatct
     5221 gaggctcatc ccgctgcctc tgtgtccaag tcttccccga gtccaccctt ggcagctgct
     5281 ggaccatcag ctaaaaccaa aggccagaaa aaagatgatg tccctgcacc agatggaaat
     5341 tcctgtcaaa tatgccatga aatattcaag tcaaaaaaca tgcgtgtgct aaaatgtggg
     5401 cacaagtttc acaaagggtg ctttaagcaa tggctgaaag ggcagagcac gtgccccacc
     5461 tgtggcagca gtgacctgct gtcagaagag taacctgttg cgccaccatc acagtcccag
     5521 cccagaagaa gatgggaccc tccttcctgt tgctgtaggt agtcactcct cactaatgca
     5581 ccatgcactt catgagttaa agaacaacaa tgtcctgttg ccagtgtaaa gacagcaaac
     5641 atggacactc tcgcactgtg catcacaaag ctaacaaatc gaaatcttga atgcagtctg
     5701 tcctaagtcc aggcaagtga cagccatgtg tgtctgcagt gctgtgtcac cacgtcctgc
     5761 attgttggag ctgctgcagg gacactgaga tgagcaggtt ctttggaaag aactgttgtg
     5821 ctcctcaaag cagtgttcag attttaaagg ttcttagcct cctcagttcc ttatgtggaa
     5881 ctgtaggatc cccttcataa atttttaaag tgcttatgtg atccaattgg tctacatttt
     5941 ggtaatcaag tataaaatac tttttaaatt agtatcagct aagaattttt tttaccctgg
     6001 gaagatgctg tctgttcaca ggagtcccac acttgacact tacactaagg ttaccatgta
     6061 agtctcatga gtcagccagt gcttggaaag gcccggctga atgcaggaca aagtgccgag
     6121 cacaggacag tcactctcac tctccttcct tattcttcct ccggaaggga aatgtactac
     6181 agtcctgacg tgttggtgtt aacattgttc tgtttgactt ttgtgtaaag taatgcatgc
     6241 aatcttgtaa tgtggcctga aaaacaagct aactgtatta gaaactattc aaaaactagg
     6301 tattttttag tgacctgtag gcagtggcaa atacagacac gtgaacccaa gatacattac
     6361 atttctttca aacacaaaga aacaaaaatg tttcccaacg tgttctctgc tgccctggag
     6421 atgctgtcac cttcgacctg tgtccatgtg atttgtggtg tcttagtgac ctagtctgta
     6481 gcttactctt tattctgaga cactgtccct ggtgtacgtg ctgtaacagt gaatgcaggc
     6541 catgctaaag tgcgcgcaca gcagcttatg gtacccgtcg ggcacagagg cgtagctatt
     6601 gagacagtga gctgtgcttc acgtcagcct gtgaacatgc cttacacttg tccagtacct
     6661 gtcaataaag agcattctca aagatcaa
//
