LOCUS       NM_001025681            1948 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Rattus norvegicus tetratricopeptide repeat domain 23 (Ttc23), mRNA.
ACCESSION   NM_001025681 XM_218762
VERSION     NM_001025681.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1948)
  AUTHORS   Breslow,D.K., Hoogendoorn,S., Kopp,A.R., Morgens,D.W., Vu,B.K.,
            Kennedy,M.C., Han,K., Li,A., Hess,G.T., Bassik,M.C., Chen,J.K. and
            Nachury,M.V.
  TITLE     A CRISPR-based screen for Hedgehog signaling provides insights into
            ciliary function and ciliopathies
  JOURNAL   Nat Genet 50 (3), 460-471 (2018)
   PUBMED   29459677
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC097953.1.
            
            On Jul 22, 2005 this sequence version replaced XM_218762.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097953.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1948              BC097953.1         1-1948
FEATURES             Location/Qualifiers
     source          1..1948
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..1948
                     /gene="Ttc23"
                     /gene_synonym="RGD1310409"
                     /note="tetratricopeptide repeat domain 23"
                     /db_xref="GeneID:308708"
                     /db_xref="RGD:1310409"
     exon            1..125
                     /gene="Ttc23"
                     /gene_synonym="RGD1310409"
                     /inference="alignment:Splign:2.1.0"
     CDS             74..1486
                     /gene="Ttc23"
                     /gene_synonym="RGD1310409"
                     /note="TPR repeat protein 23"
                     /codon_start=1
                     /product="tetratricopeptide repeat protein 23"
                     /protein_id="NP_001020852.2"
                     /db_xref="GeneID:308708"
                     /db_xref="RGD:1310409"
                     /translation="MAVTKKRKAADDKRVAPKDNAYENMQESQETHMSSHLDEVIAAV
                     SVTSKNRLSNKLLQTALFQPPREKLHLCEERAKSYSSIREYKQAIQELVRCVALTKIC
                     YGDSHWKLAEAYVNLAQGYLQLKGLSLQAKQHAEKAKEILANSMESPYYNKTDIFKCS
                     LELFYTLGKALVSLQKFKEAWENLIKAERLSKEMLQCGNIIKEEWIEIQSRIKLSFAQ
                     LYQGQKRSKEAFPYYQKALEYTETTKDEKSFECAQVLREMAGVEQALALHDASIGHFS
                     QAHLIILSKEPSPEDAADSALSIARAAVASGMHDHHDVAEKYFQESMTYLKDSEGTEK
                     AKFLSIQDEFCSFLQTIGQKERAAMILRESLEAKIGVFGDFSPEVAETYRILGRADLA
                     QGNNNGAHMKLKKCVQIETFLYGSQDKKTMATQQTIDTLSKISETPVKSKQSLKAKTA
                     FCTSVPQYVTPGKARHSAAE"
     exon            126..325
                     /gene="Ttc23"
                     /gene_synonym="RGD1310409"
                     /inference="alignment:Splign:2.1.0"
     exon            326..449
                     /gene="Ttc23"
                     /gene_synonym="RGD1310409"
                     /inference="alignment:Splign:2.1.0"
     exon            450..600
                     /gene="Ttc23"
                     /gene_synonym="RGD1310409"
                     /inference="alignment:Splign:2.1.0"
     exon            601..726
                     /gene="Ttc23"
                     /gene_synonym="RGD1310409"
                     /inference="alignment:Splign:2.1.0"
     exon            727..904
                     /gene="Ttc23"
                     /gene_synonym="RGD1310409"
                     /inference="alignment:Splign:2.1.0"
     exon            905..1010
                     /gene="Ttc23"
                     /gene_synonym="RGD1310409"
                     /inference="alignment:Splign:2.1.0"
     exon            1011..1138
                     /gene="Ttc23"
                     /gene_synonym="RGD1310409"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1288
                     /gene="Ttc23"
                     /gene_synonym="RGD1310409"
                     /inference="alignment:Splign:2.1.0"
     exon            1289..1371
                     /gene="Ttc23"
                     /gene_synonym="RGD1310409"
                     /inference="alignment:Splign:2.1.0"
     exon            1372..1923
                     /gene="Ttc23"
                     /gene_synonym="RGD1310409"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctttgaagct gcgaagggga aggtggtgta tggggccttg ggctgatttc tagtgaaatt
       61 ctgagccaca gctatggctg ttacaaagaa aagaaaggca gccgatgata agcgtgtagc
      121 tccaaaggac aatgcatatg agaatatgca agagtctcag gagactcaca tgtccagcca
      181 cctggatgaa gtcattgctg ctgtcagcgt cacttctaaa aacaggctct caaataagct
      241 gcttcagaca gcactgttcc agccccctcg agagaaactc cacctgtgtg aagagagagc
      301 gaagtcctac tccagcatcc gagagtacaa gcaggccatc caggagcttg tgcgctgtgt
      361 ggcactaacg aaaatttgct acggcgactc gcattggaaa ctagcagagg catatgtgaa
      421 tctggctcag ggttacctcc agctgaaagg gttgtcacta caagcaaagc agcatgcaga
      481 aaaagccaaa gaaatcctgg ccaactccat ggagagtccc tattacaaca agacagatat
      541 cttcaagtgt tccctagagc ttttctatac gctggggaaa gccctggtct cccttcaaaa
      601 atttaaagaa gcctgggaga acttgataaa agctgagaga ctttccaagg agatgctgca
      661 atgtgggaac attataaagg aagagtggat agaaatccaa tctcggatca agctgtcgtt
      721 tgcacagttg tatcaaggtc agaaaagatc aaaagaagct ttcccctact atcaaaaggc
      781 tttggaatat actgagacta ccaaagatga aaaaagtttt gaatgtgcac aagtactgag
      841 ggaaatggca ggcgtggagc aagccctggc actccacgac gcctccatcg gtcatttctc
      901 acaggcacat ctcatcatcc tgagtaaaga accctcccca gaggatgctg cagactctgc
      961 actctctatt gcccgggctg ccgttgcttc tgggatgcac gaccaccatg atgtggccga
     1021 gaagtatttt caggaaagca tgacttacct caaggattcc gaaggaacag aaaaagccaa
     1081 gttcctttcg attcaagatg aattttgcag ttttctgcaa accattggac aaaaagaaag
     1141 agcggccatg atcctgagag agtccctgga agcaaaaata ggagtgttcg gtgacttcag
     1201 tcctgaggtg gcagaaacat accggatcct gggcagggca gacctggctc agggaaacaa
     1261 caacggagcg cacatgaagc taaagaagtg tgtccagatt gagacgttct tgtatggatc
     1321 acaggacaag aagaccatgg ccacccagca aaccatagac acgctgtcca agatctccga
     1381 gactcccgtg aagtcaaagc aatcactgaa agccaagaca gcgttctgca ccagtgtccc
     1441 ccagtacgtg acgccaggga aggccaggca cagtgcggca gaatgatgcc cccatgtgcc
     1501 gccccccaaa aaaagctctg agaaagagct ttttggcatt gcttttagga tgctaagcaa
     1561 acctctctcc agccagaagg tggagtttag cagtcactgc agagttttaa ggctgtttgc
     1621 ttcagaatgc aatggcagtg ccatgaatct cccacatccc aactgtgaac gcccttcggg
     1681 tggttccgag ctttggttat tttctatcac caaggagatt tccccctatc atctctgtat
     1741 ggctcaaaca ctcttctgaa gttggagctt ctccacagga gaggagaccc acccaacgcc
     1801 gggcagggct cctgctcaat ccagagccac atctggggca gtgagaccct gcacaaagcc
     1861 ttccttatag gaaattaata gtaactaaga agaaaatacc aataaagaga aacttgttct
     1921 ggtaaaaaaa aaaaaaaaaa aaaaaaaa
//
