LOCUS       NP_001020852             470 aa            linear   ROD 09-FEB-2025
DEFINITION  tetratricopeptide repeat protein 23 [Rattus norvegicus].
ACCESSION   NP_001020852 XP_218762
VERSION     NP_001020852.2
DBSOURCE    REFSEQ: accession NM_001025681.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 470)
  AUTHORS   Breslow,D.K., Hoogendoorn,S., Kopp,A.R., Morgens,D.W., Vu,B.K.,
            Kennedy,M.C., Han,K., Li,A., Hess,G.T., Bassik,M.C., Chen,J.K. and
            Nachury,M.V.
  TITLE     A CRISPR-based screen for Hedgehog signaling provides insights into
            ciliary function and ciliopathies
  JOURNAL   Nat Genet 50 (3), 460-471 (2018)
   PUBMED   29459677
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC097953.1.
            
            On Oct 4, 2011 this sequence version replaced NP_001020852.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097953.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     Protein         1..470
                     /product="tetratricopeptide repeat protein 23"
                     /note="TPR repeat protein 23"
                     /calculated_mol_wt=52843
     Region          111..>238
                     /region_name="Spy"
                     /note="Predicted O-linked N-acetylglucosamine transferase,
                     SPINDLY family [Posttranslational modification, protein
                     turnover, chaperones]; COG3914"
                     /db_xref="CDD:443119"
     Region          211..278
                     /region_name="TPR_12"
                     /note="Tetratricopeptide repeat; pfam13424"
                     /db_xref="CDD:315987"
     Region          338..409
                     /region_name="TPR_12"
                     /note="Tetratricopeptide repeat; pfam13424"
                     /db_xref="CDD:315987"
     CDS             1..470
                     /gene="Ttc23"
                     /gene_synonym="RGD1310409"
                     /coded_by="NM_001025681.1:74..1486"
                     /db_xref="GeneID:308708"
                     /db_xref="RGD:1310409"
ORIGIN      
        1 mavtkkrkaa ddkrvapkdn ayenmqesqe thmsshldev iaavsvtskn rlsnkllqta
       61 lfqppreklh lceeraksys sireykqaiq elvrcvaltk icygdshwkl aeayvnlaqg
      121 ylqlkglslq akqhaekake ilansmespy ynktdifkcs lelfytlgka lvslqkfkea
      181 wenlikaerl skemlqcgni ikeewieiqs riklsfaqly qgqkrskeaf pyyqkaleyt
      241 ettkdeksfe caqvlremag veqalalhda sighfsqahl iilskepspe daadsalsia
      301 raavasgmhd hhdvaekyfq esmtylkdse gtekakflsi qdefcsflqt igqkeraami
      361 lresleakig vfgdfspeva etyrilgrad laqgnnngah mklkkcvqie tflygsqdkk
      421 tmatqqtidt lskisetpvk skqslkakta fctsvpqyvt pgkarhsaae
//
