LOCUS       NM_001271230            8658 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus tau tubulin kinase 1 (Ttbk1), mRNA.
ACCESSION   NM_001271230 XM_001066190 XM_039083519 XM_244043
VERSION     NM_001271230.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 8658)
  AUTHORS   Watanabe,T., Kakeno,M., Matsui,T., Sugiyama,I., Arimura,N.,
            Matsuzawa,K., Shirahige,A., Ishidate,F., Nishioka,T., Taya,S.,
            Hoshino,M. and Kaibuchi,K.
  TITLE     TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells
            through KIF2A phosphorylation
  JOURNAL   J Cell Biol 210 (5), 737-751 (2015)
   PUBMED   26323690
REFERENCE   2  (bases 1 to 8658)
  AUTHORS   Chen,S., Lu,F.F., Seeman,P. and Liu,F.
  TITLE     Quantitative proteomic analysis of human substantia nigra in
            Alzheimer's disease, Huntington's disease and Multiple sclerosis
  JOURNAL   Neurochem Res 37 (12), 2805-2813 (2012)
   PUBMED   22926577
REFERENCE   3  (bases 1 to 8658)
  AUTHORS   Sato,S., Xu,J., Okuyama,S., Martinez,L.B., Walsh,S.M.,
            Jacobsen,M.T., Swan,R.J., Schlautman,J.D., Ciborowski,P. and
            Ikezu,T.
  TITLE     Spatial learning impairment, enhanced CDK5/p35 activity, and
            downregulation of NMDA receptor expression in transgenic mice
            expressing tau-tubulin kinase 1
  JOURNAL   J Neurosci 28 (53), 14511-14521 (2008)
   PUBMED   19118186
REFERENCE   4  (bases 1 to 8658)
  AUTHORS   Sato,S., Cerny,R.L., Buescher,J.L. and Ikezu,T.
  TITLE     Tau-tubulin kinase 1 (TTBK1), a neuron-specific tau kinase
            candidate, is involved in tau phosphorylation and aggregation
  JOURNAL   J Neurochem 98 (5), 1573-1584 (2006)
   PUBMED   16923168
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On or before Oct 18, 2022 this sequence version replaced
            XM_039083519.1, NM_001271230.1.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-267               JAXUCZ010000009.1  21990973-21991239
            268-429             JAXUCZ010000009.1  21994295-21994456
            430-577             JAXUCZ010000009.1  21998182-21998329
            578-651             JAXUCZ010000009.1  21998806-21998879
            652-792             JAXUCZ010000009.1  21999040-21999180
            793-897             JAXUCZ010000009.1  22000183-22000287
            898-963             JAXUCZ010000009.1  22000511-22000576
            964-1056            JAXUCZ010000009.1  22000990-22001082
            1057-1182           JAXUCZ010000009.1  22001160-22001285
            1183-1337           JAXUCZ010000009.1  22003987-22004141
            1338-1569           JAXUCZ010000009.1  22006093-22006324
            1570-1748           JAXUCZ010000009.1  22006491-22006669
            1749-2310           JAXUCZ010000009.1  22009099-22009660
            2311-3863           JAXUCZ010000009.1  22029032-22030584
            3864-8658           JAXUCZ010000009.1  22031167-22035961
FEATURES             Location/Qualifiers
     source          1..8658
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q12"
     gene            1..8658
                     /gene="Ttbk1"
                     /gene_synonym="RGD1559518"
                     /note="tau tubulin kinase 1"
                     /db_xref="GeneID:316229"
                     /db_xref="RGD:1559518"
     exon            1..267
                     /gene="Ttbk1"
                     /gene_synonym="RGD1559518"
                     /inference="alignment:Splign:2.1.0"
     exon            268..429
                     /gene="Ttbk1"
                     /gene_synonym="RGD1559518"
                     /inference="alignment:Splign:2.1.0"
     CDS             322..4245
                     /gene="Ttbk1"
                     /gene_synonym="RGD1559518"
                     /EC_number="2.7.11.1"
                     /codon_start=1
                     /product="tau-tubulin kinase 1"
                     /protein_id="NP_001258159.1"
                     /db_xref="GeneID:316229"
                     /db_xref="RGD:1559518"
                     /translation="MQCLAAALKDETNMSGGGEQADILPANYVVKDRWKVLKKIGGGG
                     FGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKF
                     NYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNF
                     AMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGR
                     HDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIA
                     SLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDALLSTSTSTPPQQNTRQT
                     AAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPPILPGRPPEGLGPGPHLVPHP
                     GGPEAEVWEETDVNRNKLRINIGKTPCVEEEQSRGVGVPSSPVRAPPDSPTTPVRSLR
                     YRRVNSPESERLSTAADGRAELQERRSRMDLPGSPSRQACSSQPAQMLSVDTGHADRQ
                     ASGRMDVSASVEQEALSNAFRSVPLAEEEDFDSKEWVIIDKETELKDFPPGAEPSTSG
                     TTDEEPEELRPLPEEGEERRRLGTEPTVRPRGRGMQTLAEEDPRQMLPQPAPPQLSQA
                     DGRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQRQVFSVAPPFEVNGLPRAVPL
                     GLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQVPLAPFQPQANGKEGEEEEE
                     EDEEEEEEEEEEDEEDEEEEDEEDEDEEEEEAGALGEVLGPRSGSSSEGSERSQEGAP
                     STLLADDQKEARGRASMADGDLEPEEGSKTLVLVSPGDMKKSPVTAELAPDPDLGTLA
                     ALTPQHERPQPTGSQLDVSEPGTLSSILKSEPKPSGPGAGVGVGLVAPGAGVTAVTSP
                     FTKVERTFVHIAEKSHLNVMSSGGQAPRPEELSTGGELGLEMLSEVGAAEEGAPQPLE
                     NGMALVGPDGTEMESCALSGPPGETPSEVVTDSLPDGPALADEPAPASPQEPITKKGT
                     IISPSRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQQDLARLVMEK
                     RQGRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAAALPRKAGRAATTRS
                     RIPRPISVSMPAEGQQLPGRPHGAASATDSAITSRLQLQKPPGLATAADHRPKQPASR
                     ASGPGRAQVSKPAAPRSPGLPTSTARHSSGSPRSQSLSRKESSSPSHQARPGFPPSRG
                     VLQVRSQSEASPGGPKKGPKGKQLQTLRAATKGRPAVSEGRPGNR"
     exon            430..577
                     /gene="Ttbk1"
                     /gene_synonym="RGD1559518"
                     /inference="alignment:Splign:2.1.0"
     exon            578..651
                     /gene="Ttbk1"
                     /gene_synonym="RGD1559518"
                     /inference="alignment:Splign:2.1.0"
     exon            652..792
                     /gene="Ttbk1"
                     /gene_synonym="RGD1559518"
                     /inference="alignment:Splign:2.1.0"
     exon            793..897
                     /gene="Ttbk1"
                     /gene_synonym="RGD1559518"
                     /inference="alignment:Splign:2.1.0"
     exon            898..963
                     /gene="Ttbk1"
                     /gene_synonym="RGD1559518"
                     /inference="alignment:Splign:2.1.0"
     exon            964..1056
                     /gene="Ttbk1"
                     /gene_synonym="RGD1559518"
                     /inference="alignment:Splign:2.1.0"
     exon            1057..1182
                     /gene="Ttbk1"
                     /gene_synonym="RGD1559518"
                     /inference="alignment:Splign:2.1.0"
     exon            1183..1337
                     /gene="Ttbk1"
                     /gene_synonym="RGD1559518"
                     /inference="alignment:Splign:2.1.0"
     exon            1338..1569
                     /gene="Ttbk1"
                     /gene_synonym="RGD1559518"
                     /inference="alignment:Splign:2.1.0"
     exon            1570..1748
                     /gene="Ttbk1"
                     /gene_synonym="RGD1559518"
                     /inference="alignment:Splign:2.1.0"
     exon            1749..2310
                     /gene="Ttbk1"
                     /gene_synonym="RGD1559518"
                     /inference="alignment:Splign:2.1.0"
     exon            2311..3863
                     /gene="Ttbk1"
                     /gene_synonym="RGD1559518"
                     /inference="alignment:Splign:2.1.0"
     exon            3864..8658
                     /gene="Ttbk1"
                     /gene_synonym="RGD1559518"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcagtgcatt gtgggcagct ccccactccg ctgccgctgc cgccgtcgcc cgaggaggat
       61 cggggccggg tcgggccggg ccgggatggt cggggtcggg aggccgccgc cgccgccacc
      121 gccgccgccg ccggagggag cgggccgccc agcgccgcac tgagccgccc ccgccccgcc
      181 ccggccccgg gggatgcgcc gccccgcgcc gctgccttca ccgccgccgc cgcagccgca
      241 gccgcagccg cagcggacac cgagcaggta gatggccccc caagggcagg ccctgcgggc
      301 acccctccct ccggctggcg gatgcagtgc ctagcggctg ctcttaaaga cgaaaccaac
      361 atgagtgggg gaggggagca ggccgacatc ctgccggcca actacgtggt caaagatcgc
      421 tggaaggtgc tgaaaaagat cgggggcggg ggcttcggtg agatctatga ggccatggac
      481 ctgctgacca gggagaacgt ggccctgaag gtggagtcag cccaacagcc taagcaggtc
      541 ctcaagatgg aggtggctgt gctcaaaaag cttcaaggga aggaccacgt gtgcaggttc
      601 attggctgtg gcaggaatga gaagtttaac tatgtggtga tgcagctcca gggtcggaac
      661 ctggctgact tgcgccgcag ccagccaagg ggcactttca cactgagtac cacactgcgt
      721 ctgggcaagc agattctgga gtccattgaa gccattcact ccgtgggctt cctgcaccgt
      781 gacatcaagc cgtccaactt tgccatgggc cggctgccct ccacctacag aaagtgctac
      841 atgttggact ttgggctggc ccggcagtac actaacacca ctggggacgt ccggcctcct
      901 cggaatgtgg ccgggttccg ggggactgtc cgctacgcgt cggtcaacgc tcacaagaat
      961 cgggagatgg gccgccatga tgacctgtgg tccctcttct acatgctggt ggagtttgct
     1021 gtggggcagc tgccctggag gaagatcaag gacaaggagc aggtagggat gatcaaggag
     1081 aagtatgagc accggatgct actgaagcac atgccttccg agttccatct cttcctggac
     1141 cacatcgcca gcctcgacta cttcaccaag cccgactacc agttgatcat gtcggtgttt
     1201 gagaacagca tgaaggaacg gggcattgct gagaatgagg cctttgactg ggagaaggca
     1261 ggcactgatg cccttctgtc cacgagcacc tccaccccac cccagcagaa cacacggcag
     1321 acggcagcca tgtttggagt ggtcaatgtg acacctgtgc ccggggacct gcttcgtgag
     1381 aacactgagg atgtgctcca gggagaacac ctgagtgacc aggagaatgc acccccaatc
     1441 ctgcctggga ggcctccgga gggcttgggt cctggtcccc accttgtccc ccaccctggg
     1501 ggtcctgagg ctgaagtgtg ggaggagaca gatgtcaacc gtaacaaact gcgcatcaac
     1561 attggcaaaa caccctgtgt ggaagaagag cagagtcgag gagtcggggt ccccagctcc
     1621 ccagtgcgtg ctcccccaga ctcccctaca accccagtgc ggtctttacg ctatcggagg
     1681 gtcaatagcc cagagtcgga aaggctgtct acagcagctg atgggcgggc agaacttcag
     1741 gagaggaggt cacggatgga tctgcctggc tcaccctcac gccaggcctg ctcctcacaa
     1801 ccagctcaga tgctgtcagt ggacacaggc catgccgaca ggcaggccag tggccgcatg
     1861 gacgtgtcag cctctgtgga gcaggaggcc ctgagcaacg ccttccgctc agtgccactg
     1921 gctgaggagg aagactttga cagcaaggag tgggtcatta ttgacaagga gacagagctc
     1981 aaggacttcc ctcctggggc tgagcccagc acatcaggta ccacagatga agaacctgag
     2041 gagctgcggc ctttgcctga ggagggcgag gagaggaggc gtctggggac agagcctact
     2101 gtcaggcctc gtggacgtgg tatgcagacg ctggcagagg aggacccacg gcagatgctg
     2161 ccccagcctg caccacctca gttgagccag gctgatggcc ggtcagagac atcgcagcct
     2221 cccacgcctg gcagcccttc ccactcaccc ctgcactcgg gaccccgccc tcgacggaga
     2281 gagtcggatc ctacaggccc tcagagacag gtgttctctg tggcgccccc gtttgaggtg
     2341 aatggccttc cacgagctgt gcctctgggc ttgccctacc aggacttcaa gagagacctc
     2401 tctgattatc gagaacgggc ccggctgctc aacagggtcc gaagggtggg cttctcgcac
     2461 atgctgctca ccacaccgca ggtcccattg gctcctttcc agcctcaagc caatgggaaa
     2521 gagggtgaag aggaagagga ggaggatgaa gaggaagagg aggaagaaga ggaggaagat
     2581 gaggaagacg aggaggaaga ggatgaggaa gatgaagatg aggaggagga ggaggcaggg
     2641 gctcttgggg aggtgctggg gcctcgaagc ggctccagca gtgaggggag tgaacggagc
     2701 caggagggcg ccccatccac actgctggct gacgaccaga aagaggccag gggccgggcc
     2761 tccatggctg atggggacct ggagcctgag gagggctcca aaacgctggt gctcgtctcc
     2821 cctggtgaca tgaagaagtc accagtcact gccgaactgg cccctgaccc tgatctgggc
     2881 accttggctg cactcacccc tcagcacgag cggcctcagc ctactggaag ccagctggat
     2941 gtgtcagagc cgggcaccct gtcctccatc ctcaagtctg aacccaagcc ctcaggacct
     3001 ggagcagggg ttggggttgg gctggtggcc cctggggctg gggtcaccgc agtgacatca
     3061 cccttcacca aagtcgaaag gacctttgtt cacattgcag agaaatccca cctcaatgtc
     3121 atgtcttccg gaggacaggc ccccaggcca gaggagctga gcactggggg cgagttgggc
     3181 ctagagatgc tctctgaggt gggcgctgca gaggagggcg ccccacagcc tctggagaac
     3241 ggcatggctt tggtaggccc ggatgggacg gagatggaaa gttgtgccct gtctggccct
     3301 cctggggaga caccctcaga agtagtcaca gactcattgc ccgatggccc agcccttgcc
     3361 gatgaaccgg ctccagcatc cccacaagag ccaataacca agaaagggac catcatctcc
     3421 cccagccgcc atgccatgcc aggatctcgc cccaggagcc gcattcctgt cttgttgtct
     3481 gaagaggaca caggctcaga gccttcgggc tcactgtcgg ccaaagagcg gtggagcaag
     3541 agggctcggc cacagcagga tctggctcgc ctcgtgatgg agaagaggca gggtcggcta
     3601 ctgctgcggc tggcctcagg ggcctcctcc tcctccagcg aggagcagcg ccgtgcctct
     3661 gagacactct caggcaccgg ctccgaggag gacacgcctg cctcagagcc tgcagcagcc
     3721 ttgcctagga aggctgggcg ggcagcgacc acccggagcc ggatcccccg ccccatcagt
     3781 gtgtccatgc ctgcagaagg ccagcagctt cctggtagac cccacggtgc ggcctcagcg
     3841 accgactcgg ccatcaccag caggctccag ctgcagaagc ccccagggtt ggccactgct
     3901 gctgaccacc gtcccaaaca gcccgcaagc cgggcttccg gcccaggtcg cgcccaagtc
     3961 tccaagcccg cagcaccccg cagtcccggc ctccccacct ccaccgcgcg ccactccagc
     4021 gggtccccgc ggagccagtc cctgtcccgc aaagagagct cctccccctc gcatcaagcc
     4081 cggcctggtt tccctccatc tcggggggtc ctccaagtca gatctcagtc ggaggcctcc
     4141 ccggggggcc ccaagaaagg acccaagggg aaacaactgc agactctgcg cgcagcaacc
     4201 aaaggccggc cggcggtttc agagggtcgg cccgggaaca gataatgaca cccgcccgcg
     4261 gctctctgcg gcacccccta ccctcaccca ggtccccacc cgcagccggc cacactggag
     4321 cagcttccag cacagcctta cgcgcccgcg cgacaccgcg gccccagctt cccgcctgca
     4381 cccaccagga cgcacgtgag cacatgtggc cagcagccta gccagcccac tgacccagga
     4441 gggtgcgtct gtctgtctct gcgtcctgcc tcccttctgc cgcccctcta gcagggacag
     4501 gctcacaaca gatcctctgc cccgggaagg ctcagccact taaacgcctc tgaagactcc
     4561 acttctggag cccgacccct tcaaccacca ggtcttcttg gctgatccct agtcccccaa
     4621 ccaagggact tacacctgct tacacctcct gcgacccacc ttgtcctctt catccccacc
     4681 ttcttgtagt catcccccaa aactacccaa caggagaaac agcctcaaat tccataagtg
     4741 cgcaggctct agcttgccca gtctcccagg agccatggtg accatagaag gccgagctgg
     4801 gatcggggaa gtgggaccca gggatctttg gtctcttcag acttaagggg actcctccgg
     4861 ccttgctaaa gtcagctcta tgaaaggcac agggtgtgtg agtctttgct ccctcgtgtc
     4921 tctggggaac agatgtccct ttcttgaata ggaatgaatg gagcttctgg aagagagcac
     4981 ctgccctcct gggcaagtgt ttcgctgagt gaattaggaa tggggcttta aaaagattac
     5041 tcacttctct ggtccgctcg ctggtctagt actcaggacc ccttaccatc aggaattcct
     5101 tcctgctgtc taacctcaat cctgcatact gtagtttcag tcaactctcc tctctcaagt
     5161 tccacacagg tggagagtgg ctggctatca cctgcagtgt gttggtcgtt tgggggcttg
     5221 gggactctgt tctgactctc cttcttcctg acgtctctgc tgtgggaata gactggttca
     5281 ggcatcatct ccggatgatg gcggaggagg caggatgagg cagactggct cctccgggag
     5341 gcaaaaggcc cttctcactt tagagcgtgt gagaagtgtg tgaggtacag ctggtgccca
     5401 ctcccacctc cacccagttc accctgagcc cttcttgctc tgagccagcc cacacagctg
     5461 agctgctcca tacctgacat ggggcctcat cctgcattct gacttctgca tagctcgccc
     5521 acctcatcag gagcctcagc tgctaacatc tggagcaaac agcaccctga ctgcagatgg
     5581 gacagacagc ccctcctgtc tgggacaggg actccctgca ggccttctag aaagtactcc
     5641 cagcctccct cccctgttct ggccctgtgt ccttccctga gccacagaga gcaaaccaag
     5701 gcattctggt gaaggaaggc ctcagtatgc caccagcccg gccacatcta cacccgtgac
     5761 gaccggctga gggcagctca tgccagctga actcctcatg cagggtcagc aggtctgggc
     5821 agcagcttcc atgacatgaa agcagctcct accgaccagc taggggagga caccagggtg
     5881 ggtagtctct tgaggtctat cccacgctga cgcagaagct cccagaacac tcaggaaacc
     5941 tctctggata tatttatctc tgtcacccca cagtactcta atggccccca gtccagggaa
     6001 gggtagaggg ctcacttcct cccacccaga gctttaataa atgacaatca gctcatgcca
     6061 ggtggggacc aggccatgac cctagtgccc aggccctggg cctgcccctt gccaccaacc
     6121 gaactgtgaa tgtaggtccc tccgccccct cggtctcact tctgcagtag gaccaacaac
     6181 atccaggttt ggagattgga ggaaggggag gcctaggaaa gccccgggct caccccaccc
     6241 ccagttaaac agccagtgct ggagccggta cagatcagat gcagaggccg gtgtaccctt
     6301 gggatttcag acctatgtag ggctccaact gacctcaggc ctccgagtca gtgacatcat
     6361 caggttggga ggaagaagaa acagaggaac agcggagagg ggtggggagg gggctaagcg
     6421 gttcctctcc ccaggaagga accagggcag aggaaaccac atctcccgat gccccttgcc
     6481 cgagctgctg ccctttcctt gaggatcatc cttctcctgc actgggcccc tcaggtccct
     6541 ttccctcctc tctgagagtg gcaccccacc accatctctt atgtcccccc tcctgactgt
     6601 ctacatcact ggctcagatg tggggtatgc tcactcgatg cgccttccct ccccaaccgt
     6661 accatgtgca gagggtgcag gagaagggcc ctgccccagg cacatggctc tctggcttct
     6721 cagctcctcc ccaagggcct ggcttgctca gttgtctgag ccccttgggc aggtgttggg
     6781 ggacaaggag ctgccctccc cctccctggg aagcaacaga agaatgttta cattgccata
     6841 cagaatgtaa cagcccttgc tcacccctcc cagtcactgc atggcctctg cccaccctgt
     6901 gcctgcccac tcccctgaca ccaacacttt gcaagtcgct gtcacaacta gatggggtct
     6961 cagaagggaa gtagccatca caccattaaa aagcctgtgg acctttctgt tggcctggac
     7021 tctttttccc tttagggagg gtagggcaaa acccggcccc tgagggtggg gtgggtggga
     7081 gagaaggtac aggatggtgt ccagtgggcg gacatcttct ccacagcggg ggacaaggaa
     7141 gttcaggtct gacatgggta atttgttagg gtctgacaga acaggtttcc accctagcaa
     7201 agctctttga gctccttggt cgtttttgct aaaggctgca gagtctctgt ttggttcagc
     7261 acagagagag gcaaaactgt catttccctg aaggaagcag atagaatcaa gtatttccgg
     7321 agaagcagaa aacagcggct tacaggcaac gccatagcaa agcccaccct gaccactggc
     7381 ccgtggcgcg gcctctgcac ctgacaagtt tatcgtgtgg acaccctcga gaagccccag
     7441 agccttgtct acaaatcaga aacacaggaa gttctgaaag cagggagcat cttccttaga
     7501 tgggtgcagg ctcttcagac gggcatcaaa gcccgaaggg aagctagact tggcggcctc
     7561 atgcatgtaa ttctagcagc cacaggatgt aatgcagagg gattttggag agctccaggc
     7621 cagcctgcac tacatagtaa cttcaaaacc agcctaggca gctaaatgcc agaccatctc
     7681 aaaaaaagaa aactatagcc atggggaggc atttatattc actaatttca catgttttca
     7741 gaggaatgaa aaaattttga gacaaggtct ttccaggtag cccaggctgg ccacatttgt
     7801 gccatcttcc tgcctcaaac tcccaagtgg tgggatgaca gtataccact ctgctaagtt
     7861 agatggagac attaatgtct ttatgagaca ctgctcttga cccctattta taatatatgg
     7921 actatgcatg gaattacttt ccttcctttt aaaaaaaagt atttcatctc tctatcttct
     7981 gtgatgtcat tggttttggt aagagattgt ggtgagcaaa gcaagatcca tgcctatgac
     8041 gaggacgtca ccgtagggtg ccatgagact caaaatggag gaagtggccc ttttgtgttc
     8101 ttaagagtca gttgtgcaac taagaagaag tcacgtgtga ggggaacagc gaggatgctg
     8161 ggtctgtggc ccacaggggg tgggctggat gaaggtaggt tgccatggag aggaacagga
     8221 agtacccttt gaatcctaaa cccaccagaa gtgaatcttt ccccttagcg gacatcagaa
     8281 cagtttcttc cccaggcctg gctctgggtt tgaaagccca tcccttcctg ggggtgctgc
     8341 ccttggagat ctagaagctc agcctcctgg gacttctttc ctctaacttg aacaccagtg
     8401 ggctccgggg ccttctgggg ggcccagggg accatcgctt tcattcctgt gtatggtgtc
     8461 cagagtagga cacacttgag gtaaatgcta aaagcaaatc gaacagaaca cacccccgtg
     8521 catgactctg gccgctggag atgatttggg aacggtttgg tgtataccat cacggaactt
     8581 ttttatgttt ataataatgc cccccctctc tgtccatata tatttcttat aaataaagga
     8641 ggaacatatt atacctac
//
