LOCUS       NM_001011900            1447 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus testis-specific serine kinase 1B (Tssk1b), mRNA.
ACCESSION   NM_001011900 XM_221761
VERSION     NM_001011900.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1447)
  AUTHORS   Jha KN, Coleman AR, Wong L, Salicioni AM, Howcroft E and Johnson
            GR.
  TITLE     Heat shock protein 90 functions to stabilize and activate the
            testis-specific serine/threonine kinases, a family of kinases
            essential for male fertility
  JOURNAL   J Biol Chem 288 (23), 16308-16320 (2013)
   PUBMED   23599433
REFERENCE   2  (bases 1 to 1447)
  AUTHORS   Li Y, Sosnik J, Brassard L, Reese M, Spiridonov NA, Bates TC,
            Johnson GR, Anguita J, Visconti PE and Salicioni AM.
  TITLE     Expression and localization of five members of the testis-specific
            serine kinase (Tssk) family in mouse and human sperm and testis
  JOURNAL   Mol Hum Reprod 17 (1), 42-56 (2011)
   PUBMED   20729278
REFERENCE   3  (bases 1 to 1447)
  AUTHORS   Zhang L, Yan Y, Liu Z, Abliz Z and Liu G.
  TITLE     Identification of peptide substrate and small molecule inhibitors
            of testis-specific serine/threonine kinase1 (TSSK1) by the
            developed assays
  JOURNAL   J Med Chem 52 (14), 4419-4428 (2009)
   PUBMED   19530700
REFERENCE   4  (bases 1 to 1447)
  AUTHORS   Xu B, Hao Z, Jha KN, Zhang Z, Urekar C, Digilio L, Pulido S,
            Strauss JF 3rd, Flickinger CJ and Herr JC.
  TITLE     Targeted deletion of Tssk1 and 2 causes male infertility due to
            haploinsufficiency
  JOURNAL   Dev Biol 319 (2), 211-222 (2008)
   PUBMED   18533145
REFERENCE   5  (bases 1 to 1447)
  AUTHORS   Jaleel M, McBride A, Lizcano JM, Deak M, Toth R, Morrice NA and
            Alessi DR.
  TITLE     Identification of the sucrose non-fermenting related kinase SNRK,
            as a novel LKB1 substrate
  JOURNAL   FEBS Lett 579 (6), 1417-1423 (2005)
   PUBMED   15733851
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083661.1.
            
            On Feb 11, 2005 this sequence version replaced XM_221761.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC083661.1, AY346103.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1447
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q23"
     gene            1..1447
                     /gene="Tssk1b"
                     /gene_synonym="Stk22a; Tssk1"
                     /note="testis-specific serine kinase 1B"
                     /db_xref="GeneID:288358"
                     /db_xref="RGD:1307352"
     exon            1..1424
                     /gene="Tssk1b"
                     /gene_synonym="Stk22a; Tssk1"
                     /inference="alignment:Splign:2.1.0"
     CDS             117..1214
                     /gene="Tssk1b"
                     /gene_synonym="Stk22a; Tssk1"
                     /EC_number="2.7.11.1"
                     /note="spermiogenesis associated; serine/threonine kinase
                     22A (spermiogenesis associated); testis-specific serine
                     kinase 1"
                     /codon_start=1
                     /product="testis-specific serine/threonine-protein kinase
                     1"
                     /protein_id="NP_001011900.1"
                     /db_xref="GeneID:288358"
                     /db_xref="RGD:1307352"
                     /translation="MDDAAVLKRRGYIMGINLGEGSYAKVKSAYSERLKFNVAVKIID
                     RKKAPTDFLEKFLPREIEILAMLNHRSIVKTYEIFETSDGKVYIVMELGVQGDLLEFI
                     KTRGALQEDDARKKFHQLSSAIKYCHDLDVVHRDLKCENLLLDKDFNIKLSDFGFSKR
                     CLRDDSGRLTLSKTFCGSAAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDD
                     SNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYRMLQPDVNRRLHIDEILSHCWVQPKT
                     RGLSSGAINKEGESSRAAEPSWTPEPGADKKSATKLEPKEEARAEAQSETKPQEDNVQ
                     VARQSENVGLSSELNRATEEGHPQQPSETHT"
ORIGIN      
        1 gcaggcctgg ccagctcaga ggactctctg tccacagtat aaatgaaaac actgctggcc
       61 catgtctggc agggatgtag agggcagcct cagaggcact gggcactccc ggcaccatgg
      121 atgacgcagc cgtcctcaag cgacgaggct acatcatggg gataaactta ggagagggct
      181 cgtatgccaa agtcaaatcc gcttactctg agcgcctaaa gttcaacgtg gcggtcaaga
      241 tcatcgaccg caagaaagcc cccacggact tcctggagaa attccttccc cgggagattg
      301 agattctggc catgctaaac caccgctcta ttgtcaagac ctatgagatc tttgagacgt
      361 cagatggcaa ggtctacatt gtcatggagc ttggggtcca gggtgacctc cttgaattca
      421 tcaaaaccag aggagccctg caagaggatg atgctcgaaa gaagttccac cagctctcct
      481 cggccatcaa gtactgccac gacctggatg tcgtccaccg agacctcaag tgtgagaacc
      541 ttctgcttga caaggacttc aacatcaaac tgtctgactt tggcttctcc aagcgctgct
      601 tgcgggatga tagtggtcgg ctgacattaa gcaagacctt ctgtgggtca gcagcttatg
      661 cggcccccga ggtgctgcag ggcatcccct accagcccaa ggtgtatgac atctggagcc
      721 tgggtgtgat cctctacatc atggtctgtg gctccatgcc ctacgatgac tccaacatca
      781 aaaagatgct gcgcatccag aaggagcacc gcgtcaactt cccacgctcc aaacacctga
      841 ctggtgagtg caaggacctc atctaccgaa tgttgcagcc agatgtcaac cggaggctgc
      901 acattgatga gatcctcagc cactgctggg tgcagcccaa gactcgaggt ctgtcctctg
      961 gagccatcaa caaggaaggg gaaagctccc gggccgctga gccctcatgg acccctgaac
     1021 ctggtgctga taagaagtct gccaccaagt tggagcctaa ggaagaggca cgagctgagg
     1081 cccaatctga gacaaaaccc caggaagata atgtgcaggt ggccaggcag tcagagaacg
     1141 tgggcctcag cagcgaactg aacagggcca cagaggaagg gcatccccaa cagccttcag
     1201 agacacatac ttagtgagcc tcttgcagcc cagggggcca gcagggaagg aggcagagct
     1261 catggcttga agcctgagcc tagaagtcaa gggacgagag agagaaggaa gacactcccg
     1321 gatgagctat tttcgtcact ttcttctccc cctcctttga acttggtaac tcacatggct
     1381 aaagaagcaa taaaccacta tatgggtgca caccctcagg tgaaaaaaaa aaaaaaaaaa
     1441 aaaaaaa
//
