LOCUS       NM_001399004            3330 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus TSR1, ribosome maturation factor (Tsr1), mRNA.
ACCESSION   NM_001399004 XM_002727774
VERSION     NM_001399004.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3330)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Dec 29, 2021 this sequence version replaced XM_002727774.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR23984936.281980.1,
                                           SRR26360190.2946065.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-133               JAXUCZ010000010.1  60258790-60258922
            134-237             JAXUCZ010000010.1  60259082-60259185
            238-457             JAXUCZ010000010.1  60259740-60259959
            458-592             JAXUCZ010000010.1  60260063-60260197
            593-1017            JAXUCZ010000010.1  60260998-60261422
            1018-1177           JAXUCZ010000010.1  60262469-60262628
            1178-1338           JAXUCZ010000010.1  60263094-60263254
            1339-1532           JAXUCZ010000010.1  60265000-60265193
            1533-1695           JAXUCZ010000010.1  60266029-60266191
            1696-1806           JAXUCZ010000010.1  60266407-60266517
            1807-1939           JAXUCZ010000010.1  60267120-60267252
            1940-2056           JAXUCZ010000010.1  60268412-60268528
            2057-2197           JAXUCZ010000010.1  60268776-60268916
            2198-2272           JAXUCZ010000010.1  60269003-60269077
            2273-3330           JAXUCZ010000010.1  60269181-60270238
FEATURES             Location/Qualifiers
     source          1..3330
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..3330
                     /gene="Tsr1"
                     /note="TSR1, ribosome maturation factor"
                     /db_xref="GeneID:100360406"
                     /db_xref="RGD:2322150"
     exon            1..133
                     /gene="Tsr1"
                     /inference="alignment:Splign:2.1.0"
     CDS             37..2451
                     /gene="Tsr1"
                     /note="TSR1, 20S rRNA accumulation, homolog;
                     rCG34104-like"
                     /codon_start=1
                     /product="pre-rRNA-processing protein TSR1 homolog"
                     /protein_id="NP_001385933.1"
                     /db_xref="GeneID:100360406"
                     /db_xref="RGD:2322150"
                     /translation="MAAHRSGPLKQQNKAHKGGRHHGGGSAQRDSKGRVGPKILCKKL
                     KKQLSRVDQRHRASQLRKQKREAVLAEKRQLGSKDGPPHQVLVVPLHNRICLPEAFKL
                     LQNEDLGTVYLNERGSTHSFMLLSPSLKHRWSFTYARPGDLHTLLDMAKVADTILFLL
                     DPLEGWDSTGDYCLSCLFAQGLPTYMLAVQGLPSLPPKRQTDARKKLNKTVEKRFPED
                     KLLLLDTQQESGMLLRQLANQKQRHLAFRDRRAYLFAHDADFMPSEESDLVGTLKISG
                     YIRGRTLNVNSLLHIVGHGDFQMNQIDAPVDPFPLNPRVVKSQKKPSMSMEVCVTDAA
                     ADMEEGLKVLMKADPDQQETLQTEVIPDPMEGEQTWPTEEELDEANDSLKQRSRVVKK
                     VPKGTSNYQAEWILDEGDESDGEGDESDDDIQHEGFMEEESQDGSGEEEEEECETMTL
                     GESVRDDLYDEKVDEEDEERMLEKYKQERLEEMFPDEMDTPRDVAARIRFQKYRGLKS
                     FRTSPWDPKENLPRDYARIFQFQNFVNTRKRIFKEIEEKETEGAEVGWYVTLHVSNVP
                     VSVVESFRQGAPLIAFSLLPYEQKMSVLNMVVSRSPGNTEPVKAKEELIFHCGFRRFR
                     ASPLFSQHTAADKHKFQRFLTADAALVVTVFAPITFPPASVLLFKQRRNGMHSLIATG
                     HLFSVDPDRMVIKRVVLSGHPFKIFTKTAVVRYMFFSRDDVLWFKPVELRTKWGRRGH
                     IKEPLGTHGHMKCSFDGKLKSQDTVLMNLYKRVFPKWTYDPYVPEPVLWVKSDISSTV
                     SEVDME"
     exon            134..237
                     /gene="Tsr1"
                     /inference="alignment:Splign:2.1.0"
     exon            238..457
                     /gene="Tsr1"
                     /inference="alignment:Splign:2.1.0"
     exon            458..592
                     /gene="Tsr1"
                     /inference="alignment:Splign:2.1.0"
     exon            593..1017
                     /gene="Tsr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1018..1177
                     /gene="Tsr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1178..1338
                     /gene="Tsr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1339..1532
                     /gene="Tsr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1533..1695
                     /gene="Tsr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1696..1806
                     /gene="Tsr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1807..1939
                     /gene="Tsr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1940..2056
                     /gene="Tsr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2057..2197
                     /gene="Tsr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2198..2272
                     /gene="Tsr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2273..3330
                     /gene="Tsr1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaagtagtgt ttactcggtg cacgtgggca gttagaatgg cggctcaccg ctccgggccg
       61 ctgaagcagc agaataaagc tcataaaggc gggcggcacc acggcggtgg gtccgcacaa
      121 cgggacagca aaggtcgtgt aggaccgaaa atcctgtgca agaagcttaa gaagcagctc
      181 agccgagtag accagaggca tcgcgccagc cagctccgaa agcagaagag ggaggcggtt
      241 ctggcagaga agaggcagct gggcagcaag gatgggcctc cacatcaggt gctggtggtg
      301 cctctgcaca acaggatttg ccttccagag gcatttaaac tgcttcagaa cgaagacctg
      361 ggaacagtgt atttgaatga acggggaagc acccatagtt ttatgcttct gagccctagc
      421 ttgaaacatc ggtggtcttt cacatatgca agaccagggg atctgcatac actattagac
      481 atggctaaag ttgctgatac catcctgttc ctcctggacc cattagaagg ctgggacagt
      541 actggggatt attgtctatc ttgcctcttt gctcagggcc ttcccaccta tatgctagct
      601 gtccagggac ttcctagtct cccaccaaag agacaaacgg atgccagaaa gaagctaaat
      661 aaaacagtgg agaaacgctt tcctgaagac aaactcctgc tgctggacac ccagcaagaa
      721 tcaggaatgt tactcagaca gttggctaac cagaagcaaa ggcatcttgc ttttcgggat
      781 cggcgagctt acttgtttgc ccatgatgct gacttcatgc ctagtgagga gagtgactta
      841 gtgggcacct tgaaaatctc aggctacatt cgagggagga ctctgaatgt aaatagtttg
      901 ctgcatattg ttggacatgg tgatttccaa atgaatcaaa tagacgcgcc tgtggatcct
      961 ttccctttaa atcctagagt ggttaaatcc caaaagaaac caagcatgtc aatggaggtt
     1021 tgtgttacag acgctgctgc tgacatggaa gaaggtctta aggttctgat gaaggcagac
     1081 cctgatcaac aggaaacttt acaaacagag gttattccag acccaatgga aggcgagcaa
     1141 acgtggccca ctgaggagga gctggatgag gcaaatgact cactgaagca acgctccagg
     1201 gtggtaaaga aggtccctaa aggaacatcc aattaccagg ctgagtggat tctggatgaa
     1261 ggcgatgaaa gtgatgggga aggtgatgaa tctgatgatg acatacagca tgaaggtttc
     1321 atggaagaag agtctcagga tgggagtggc gaggaggaag aggaggaatg tgaaaccatg
     1381 actctagggg agtctgtgcg tgatgaccta tacgatgaga aagtagatga agaggacgag
     1441 gagagaatgt tagagaaata caaacaagaa agattggaag agatgtttcc agatgaaatg
     1501 gatacccctc gtgatgtggc cgctagaatt cgatttcaga aatatagagg cctcaagagc
     1561 ttccggacgt ctccttggga ccctaaagaa aaccttccta gagattatgc tcggattttt
     1621 cagtttcaga attttgttaa taccagaaaa agaatcttta aagagattga ggaaaaagaa
     1681 actgaaggag ctgaggttgg ttggtacgtc acacttcatg tttctaatgt ccctgtctcg
     1741 gtggtcgagt ctttcaggca aggagcgccc ttgattgcat tttctttgct accttatgaa
     1801 cagaagatgt cagtattgaa catggtggtg agccgcagcc ctggcaacac ggaacctgtg
     1861 aaggcgaaag aagaattgat cttccactgt ggattcaggc gcttccgagc ttcaccttta
     1921 ttctctcagc acacagcagc tgataaacat aaatttcaaa gattcctgac tgctgatgcg
     1981 gccttagtgg tgacagtatt tgcaccaatc acgttccctc ctgcatctgt gctgcttttc
     2041 aagcagagga gaaatggaat gcacagcctc attgctacag gccatctgtt ttcagtggat
     2101 ccagacagga tggtcataaa gagagtggtt ctaagtggtc atcctttcaa aatttttact
     2161 aagacggcag tagtgcgcta catgttcttc agcagagacg atgtgctgtg gtttaagcct
     2221 gtggaactga gaaccaagtg gggccgccgg ggacacatca aagagccgct gggtacacat
     2281 ggccatatga agtgcagttt tgatgggaag ctaaaatctc aggatacagt attaatgaat
     2341 ctctataagc gagtgtttcc caaatggact tatgacccgt atgtaccaga gccagtactt
     2401 tgggttaaaa gtgacatctc ttcaacagtg tctgaagtag acatggagta atggccactc
     2461 agttgggttc ctccagccaa ggctccagtg ttggagttgt tgggttgtga ctaggctgtc
     2521 tgtgtctctg ctaagtacag gatttatact ataacatact tgattgggat tttgaaaata
     2581 gtttaaacag gaagatggaa aacaaaactt tcatctagag actaaattgg aacagaaaca
     2641 gtctgttaag gagccggccg ttccgcctgc ttcacccagc ttagggaggt taagtctaca
     2701 ttcccaccac tgagtacaat acagatgttc tttacttctg gagagacagt ttggaaatgc
     2761 tgagatagca ctgcagccaa tccgacgcca gcagtaggct caatgagcag tttcattctt
     2821 tcccacacca gctgggttgc atactgttgc acagaaagaa gcaagggtta gtgaaaccag
     2881 aaattgtaaa catgaagtag gtgagctacc atttcccaca ggttaaggga atggtctgtc
     2941 agtgcctggg aagttagact ggctgtttat gcatctgagt ttaccttgat ttcatcttcc
     3001 gtgacagtga agacatcgtc cacaaggtcc cttataatag gccaggtatt taagccaatg
     3061 ctggacttga cgccatctgc tatggtctct ggaggatgaa gattgggggt cagctctcct
     3121 ttcagcttag actggtagca gtcatctgca ttggaaggtt cagcagcgta caccttcacg
     3181 ctaggtttca gggtctggga aaggaagaga tacattaaat accgccgttg tctgcacacc
     3241 tcaaggaggc agtgtgctaa agatgtgtta catttgatga ccaaaatgga aacgaccttg
     3301 aagcacttta ataaaaattg tatctgataa
//
