LOCUS       NM_001398737            1722 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus tetraspanin 7 (Tspan7), mRNA.
ACCESSION   NM_001398737 XM_039099868
VERSION     NM_001398737.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1722)
  AUTHORS   Pang,S., Luo,Z., Dong,W., Gao,S., Chen,W., Liu,N., Zhang,X.,
            Gao,X., Li,J., Gao,K., Shi,X., Guan,F., Zhang,L. and Zhang,L.
  TITLE     Integrin beta1/FAK/SRC signal pathway is involved in autism
            spectrum disorder in Tspan7 knockout rats
  JOURNAL   Life Sci Alliance 6 (3), e202201616 (2022)
   PUBMED   36625203
  REMARK    GeneRIF: Integrin beta1/FAK/SRC signal pathway is involved in
            autism spectrum disorder in Tspan7 knockout rats.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1722)
  AUTHORS   Bassani,S., Cingolani,L.A., Valnegri,P., Folci,A., Zapata,J.,
            Gianfelice,A., Sala,C., Goda,Y. and Passafaro,M.
  TITLE     The X-linked intellectual disability protein TSPAN7 regulates
            excitatory synapse development and AMPAR trafficking
  JOURNAL   Neuron 73 (6), 1143-1158 (2012)
   PUBMED   22445342
REFERENCE   3  (bases 1 to 1722)
  AUTHORS   Dai,C., Liang,D., Li,H., Sasaki,M., Dawson,T.M. and Dawson,V.L.
  TITLE     Functional identification of neuroprotective molecules
  JOURNAL   PLoS One 5 (11), e15008 (2010)
   PUBMED   21124846
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1722)
  AUTHORS   Kuroiwa,A., Watanabe,T., Hishigaki,H., Takahashi,E., Namikawa,T.
            and Matsuda,Y.
  TITLE     Comparative FISH mapping of mouse and rat homologues of twenty-five
            human X-linked genes
  JOURNAL   Cytogenet Cell Genet 81 (3-4), 208-212 (1998)
   PUBMED   9730605
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On Dec 22, 2021 this sequence version replaced XM_039099868.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158792.1, EF688600.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840115, SAMN16676784
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-84                JAXUCZ010000021.1  14978544-14978627   c
            85-273              JAXUCZ010000021.1  14898094-14898282   c
            274-348             JAXUCZ010000021.1  14896542-14896616   c
            349-444             JAXUCZ010000021.1  14894597-14894692   c
            445-600             JAXUCZ010000021.1  14892571-14892726   c
            601-684             JAXUCZ010000021.1  14887232-14887315   c
            685-760             JAXUCZ010000021.1  14882560-14882635   c
            761-1722            JAXUCZ010000021.1  14881327-14882288   c
FEATURES             Location/Qualifiers
     source          1..1722
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq12"
     gene            1..1722
                     /gene="Tspan7"
                     /gene_synonym="A15; DXS1692E; MXS1; TALLA-1; Tm4sf2"
                     /note="tetraspanin 7"
                     /db_xref="GeneID:363447"
                     /db_xref="RGD:1589725"
     exon            1..84
                     /gene="Tspan7"
                     /gene_synonym="A15; DXS1692E; MXS1; TALLA-1; Tm4sf2"
                     /inference="alignment:Splign:2.1.0"
     CDS             4..753
                     /gene="Tspan7"
                     /gene_synonym="A15; DXS1692E; MXS1; TALLA-1; Tm4sf2"
                     /note="neuroprotective protein 5; Transmembrane 4,
                     superfamily member 2 (cell surface glycoprotein A15);
                     transmembrane 4 superfamily member 2"
                     /codon_start=1
                     /product="tetraspanin-7"
                     /protein_id="NP_001385666.1"
                     /db_xref="GeneID:363447"
                     /db_xref="RGD:1589725"
                     /translation="MASRRMETKPVITCLKTLLIIYSFVFWITGAILLAVGVWGKLTL
                     GTYISLIAENSTNAPYVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAE
                     LVAGISGFVFRHEIKDTFLRTYTDAMQNYNGKDERSRAVDHVQRSLSCCGVQNYTNWS
                     SSPYFLEHGIPPSCCMNETDCNPLDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAG
                     VAFGIAFSQLIGMLLACCLSRFITANQYEMV"
     exon            85..273
                     /gene="Tspan7"
                     /gene_synonym="A15; DXS1692E; MXS1; TALLA-1; Tm4sf2"
                     /inference="alignment:Splign:2.1.0"
     exon            274..348
                     /gene="Tspan7"
                     /gene_synonym="A15; DXS1692E; MXS1; TALLA-1; Tm4sf2"
                     /inference="alignment:Splign:2.1.0"
     exon            349..444
                     /gene="Tspan7"
                     /gene_synonym="A15; DXS1692E; MXS1; TALLA-1; Tm4sf2"
                     /inference="alignment:Splign:2.1.0"
     exon            445..600
                     /gene="Tspan7"
                     /gene_synonym="A15; DXS1692E; MXS1; TALLA-1; Tm4sf2"
                     /inference="alignment:Splign:2.1.0"
     exon            601..684
                     /gene="Tspan7"
                     /gene_synonym="A15; DXS1692E; MXS1; TALLA-1; Tm4sf2"
                     /inference="alignment:Splign:2.1.0"
     exon            685..760
                     /gene="Tspan7"
                     /gene_synonym="A15; DXS1692E; MXS1; TALLA-1; Tm4sf2"
                     /inference="alignment:Splign:2.1.0"
     exon            761..1722
                     /gene="Tspan7"
                     /gene_synonym="A15; DXS1692E; MXS1; TALLA-1; Tm4sf2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtatggcat cgaggagaat ggagaccaaa cctgtgataa cctgtctcaa aaccctcctc
       61 atcatctact ccttcgtctt ctggatcaca ggggcgatcc tgttggctgt tggagtctgg
      121 ggaaagctga ctttgggaac ctacatctcc cttattgcgg agaactccac aaatgctccc
      181 tacgtgctca ttggaaccgg caccaccatt gtggtctttg gcctctttgg atgctttgct
      241 acgtgccgtg gtagcccatg gatgctgaaa ctgtatgcca tgttcctgtc cctggtgttc
      301 ctggctgagc tggttgctgg catttctgga tttgtgtttc gtcatgagat caaggacacc
      361 ttcctgagga cttacacgga tgccatgcag aactacaacg gcaaagatga aaggagccgg
      421 gcagtggacc atgtgcagcg cagcctgagc tgctgtggcg tgcagaacta caccaactgg
      481 agcagcagcc cctacttcct ggaacatggt atccccccca gttgctgcat gaacgaaact
      541 gattgtaatc cgctggatct gcacaatctg actgtggctg ccaccaaagt taaccaaaag
      601 ggctgttatg atctggtgac cagttttatg gagactaaca tggggatcat tgctggagtg
      661 gcatttggaa tcgcattctc ccagttgatt ggcatgctgc tggcctgctg tctgtcccgg
      721 ttcatcactg ccaatcagta cgagatggtg taaagagaag tctttcaaga attctggaat
      781 aagaggcctg tttttaaaaa aggaactgcc gcaatctgaa agacttccaa agaacgttag
      841 agcacagtac atactacccc tgccctgctc ccaccacccg ctctccacaa ccctccccca
      901 tgtgcaactg acactcctcc ccagtcgatg ctcctaccta cctttcagcc cacgtcattc
      961 gtagtgtcca tcttgtgaag ccctgttgtg ccacacagtg tagccagccc ccctgcagct
     1021 agtcatagtg aaccccgccc taaggccctg tgaagtgcca gctccctcac atgtacttgg
     1081 tccaactgta ggtgactggt tatcacatcc tcactggccc ctgtggcctt gcatgtagta
     1141 ggggaggctt cagtcagccc ctcgctgtgg tccaagaatg ccacacactt ttctgtagat
     1201 aatgcagatg gtaattatct tttctttctg gcttaatctg atttggtttg cttttccctt
     1261 tcctgggatt ctttcctacc ttctttaggc tgtctagcac attagaggag acacagtggg
     1321 agggattcat gaggagaaaa cagcatgtgg cgtgcatggc agaaagtgct aagtattagc
     1381 tgctgccttg ctcattgttc caagaggtgg gtgtggagag atcctgttac aaggttgtgt
     1441 tgttacttcc ctggaaggca aagacgctac ttttgatttg ccccaactaa tttctattat
     1501 tttgcctttt ctttccgtat gttattttct ttcttgcatt gacattatag actttgagga
     1561 cctcatcaga tcaatttaaa agtgagtgtg gaagggaaac aaaggtcaac atatttttaa
     1621 aagatcttaa aaataatgcc tctgtctagc atgccaacaa gaatgcattg atattgtgaa
     1681 catttgtgat acacgtatta ataaatagag caattacaaa ta
//
