LOCUS       NM_001100672            1639 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus tetraspanin 6 (Tspan6), mRNA.
ACCESSION   NM_001100672 XM_001067945 XM_217563
VERSION     NM_001100672.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1639)
  AUTHORS   Wang Y, Tong X, Omoregie ES, Liu W, Meng S and Ye X.
  TITLE     Tetraspanin 6 (TSPAN6) negatively regulates retinoic acid-inducible
            gene I-like receptor-mediated immune signaling in a
            ubiquitination-dependent manner
  JOURNAL   J Biol Chem 287 (41), 34626-34634 (2012)
   PUBMED   22908223
REFERENCE   2  (bases 1 to 1639)
  AUTHORS   Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE and
            Yates JR.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   3  (bases 1 to 1639)
  AUTHORS   Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta
            R, Wang NS and Knepper MA.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   4  (bases 1 to 1639)
  AUTHORS   Matsuda A, Suzuki Y, Honda G, Muramatsu S, Matsuzaki O, Nagano Y,
            Doi T, Shimotohno K, Harada T, Nishida E, Hayashi H and Sugano S.
  TITLE     Large-scale identification and characterization of human genes that
            activate NF-kappaB and MAPK signaling pathways
  JOURNAL   Oncogene 22 (21), 3307-3318 (2003)
   PUBMED   12761501
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC158651.1.
            
            On or before May 31, 2008 this sequence version replaced
            XM_001067945.1, XM_217563.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158651.1, FQ213424.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMN16093044
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1639
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq32"
     gene            1..1639
                     /gene="Tspan6"
                     /note="tetraspanin 6"
                     /db_xref="GeneID:302313"
                     /db_xref="RGD:1560160"
     exon            1..106
                     /gene="Tspan6"
                     /inference="alignment:Splign:2.1.0"
     CDS             20..757
                     /gene="Tspan6"
                     /codon_start=1
                     /product="tetraspanin-6"
                     /protein_id="NP_001094142.1"
                     /db_xref="GeneID:302313"
                     /db_xref="RGD:1560160"
                     /translation="MASPSRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWGKV
                     SLENYFSLLNEKATNVPFVLIGTGTVIILLGTFGCFATCRASAWMLKLYAMFLTLIFL
                     VELVAAIVGFVFRHEIKNSFKSNYENALKEYNSTRDYRSEAVDKIQSTLHCCGVTNYR
                     DWKGTNYYSETGFPKSCCKLEGCYPQRDADKVNEEGCFIKVMTTIESEMGVVAGISFG
                     VACFQLIGIFLAYCLSRAITNNQYEIV"
     exon            107..295
                     /gene="Tspan6"
                     /inference="alignment:Splign:2.1.0"
     exon            296..370
                     /gene="Tspan6"
                     /inference="alignment:Splign:2.1.0"
     exon            371..469
                     /gene="Tspan6"
                     /inference="alignment:Splign:2.1.0"
     exon            470..604
                     /gene="Tspan6"
                     /inference="alignment:Splign:2.1.0"
     exon            605..688
                     /gene="Tspan6"
                     /inference="alignment:Splign:2.1.0"
     exon            689..795
                     /gene="Tspan6"
                     /inference="alignment:Splign:2.1.0"
     exon            796..1616
                     /gene="Tspan6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcagggtctc ggggtagtca tggcgtcccc atctcggaga ctgcagacca agccagtcat
       61 tacttgtttc aaaagcgttc tcttgatcta cactttcatc ttttggatca ctggtgttat
      121 ccttcttgcc gttggcattt ggggcaaggt gagcctggaa aattattttt ccctcttaaa
      181 tgagaaggcc accaatgtgc cttttgtgct cattggcaca ggcactgtca ttattctctt
      241 gggcaccttt ggttgttttg ctacctgccg agcctcagca tggatgctga aactgtatgc
      301 gatgtttctg actctcattt ttttggtcga gctagttgca gccattgtag gatttgtttt
      361 cagacatgag attaagaaca gcttcaaaag taactacgaa aatgctctga aggagtacaa
      421 ctccacaaga gactatagaa gtgaagctgt agacaagatc caaagtacgt tgcattgctg
      481 tggggtcacc aattacaggg attggaaagg tacaaactat tactcagaaa caggatttcc
      541 caagagctgc tgtaaactgg aaggctgtta tccacagaga gatgcagata aagtcaacga
      601 agagggttgt ttcataaagg taatgacaac tatagagtca gaaatgggag tcgttgctgg
      661 aatttctttt ggagttgctt gctttcagct aattggaatc tttctcgcct actgcctctc
      721 tcgtgccata acgaataatc agtatgagat agtataatca gtatgaacac gggcttatat
      781 ctcttcagtt ctaaggttac ctttgtgagt tataacagcg cctggatgga gactgacaca
      841 ttagcctgaa aagctacacc agtagactga ttcaatcaag atatttgtgt attgtgttct
      901 atgtccactt tctgtcctat tcttacaccc ctgtatctct aaaacactgg aagagctagt
      961 aaattgtaca tgaaataata ctgtgcttcc attggatttt cttttccagt gtgggaattg
     1021 tgaggagtgc tgtggatttg ctctcttcat agcagtgttc ctgatggaag tttaacctct
     1081 acaaatttgc tgttgacgta gtgtgattga aaattggcct ccttaagtgg gcctcctatt
     1141 agtcaagatt agctggcttg attgtgtaat ctgcaacaaa aaggacaatg tttccttagt
     1201 ctctgatggt aggcagagtg gcatggtata ccattccagc tagtcatcac atggtgccca
     1261 tcattggcat tcctgggtgg tggtgccagt ctcaggcttt gggtgcaaag gacagagact
     1321 aagaactgct acctgtattt tgtgatacat caactttcag cacacaacgt atgtattttt
     1381 gtttccaaac taaggccttt atactgatca gaccttgtta tttgaaaggt tatcctttag
     1441 tggcatcaga actcttgtat tttccttata atttactgga acttacttga ttaactttag
     1501 ctagattttc cagcaaataa tacttcatat caactgtcaa cattttggtg aattttaata
     1561 gtatttgttt tgttttgtac ccttgattaa taaatataaa tcctttacac aataaaaaaa
     1621 aaaaaaaaaa aaaaaaaaa
//
