LOCUS       NM_001109227            1983 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus tetraspanin 33 (Tspan33), mRNA.
ACCESSION   NM_001109227 XM_001062106 XM_575419
VERSION     NM_001109227.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1983)
  AUTHORS   Shah J, Rouaud F, Guerrera D, Vasileva E, Popov LM, Kelley WL,
            Rubinstein E, Carette JE, Amieva MR and Citi S.
  TITLE     A Dock-and-Lock Mechanism Clusters ADAM10 at Cell-Cell Junctions to
            Promote alpha-Toxin Cytotoxicity
  JOURNAL   Cell Rep 25 (8), 2132-2147 (2018)
   PUBMED   30463011
REFERENCE   2  (bases 1 to 1983)
  AUTHORS   Haining EJ, Yang J, Bailey RL, Khan K, Collier R, Tsai S, Watson
            SP, Frampton J, Garcia P and Tomlinson MG.
  TITLE     The TspanC8 subgroup of tetraspanins interacts with A disintegrin
            and metalloprotease 10 (ADAM10) and regulates its maturation and
            cell surface expression
  JOURNAL   J Biol Chem 287 (47), 39753-39765 (2012)
   PUBMED   23035126
REFERENCE   3  (bases 1 to 1983)
  AUTHORS   Dornier E, Coumailleau F, Ottavi JF, Moretti J, Boucheix C, Mauduit
            P, Schweisguth F and Rubinstein E.
  TITLE     TspanC8 tetraspanins regulate ADAM10/Kuzbanian trafficking and
            promote Notch activation in flies and mammals
  JOURNAL   J Cell Biol 199 (3), 481-496 (2012)
   PUBMED   23091066
  REMARK    Erratum:[J Cell Biol. 2016 May 23;213(4):495-6. PMID: 27185832]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473959.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_575419.2, XM_001062106.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132291,
                              SAMD00132295 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1983
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q22"
     gene            1..1983
                     /gene="Tspan33"
                     /gene_synonym="RGD1560915"
                     /note="tetraspanin 33"
                     /db_xref="GeneID:500065"
                     /db_xref="RGD:1560915"
     exon            1..305
                     /gene="Tspan33"
                     /gene_synonym="RGD1560915"
                     /inference="alignment:Splign:2.1.0"
     CDS             204..1055
                     /gene="Tspan33"
                     /gene_synonym="RGD1560915"
                     /codon_start=1
                     /product="tetraspanin-33"
                     /protein_id="NP_001102697.1"
                     /db_xref="GeneID:500065"
                     /db_xref="RGD:1560915"
                     /translation="MARRPGVPAAYGEEFSFVSPLVKYLLFFFNMLFWVISMVMVAVG
                     VYARLMKHAEAALACLAVDPAILLIVVGVLMFLLTFCGCIGSLRENICLLQTFSLCLT
                     IVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRDDLDLQNLIDFGQKKFSCCGGI
                     SYRDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPNQAVINTMCGQGMQALDYLEASKV
                     IYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQVLVNQIKDQIKLQLYNQQ
                     HRADPWY"
     exon            306..363
                     /gene="Tspan33"
                     /gene_synonym="RGD1560915"
                     /inference="alignment:Splign:2.1.0"
     exon            364..491
                     /gene="Tspan33"
                     /gene_synonym="RGD1560915"
                     /inference="alignment:Splign:2.1.0"
     exon            492..566
                     /gene="Tspan33"
                     /gene_synonym="RGD1560915"
                     /inference="alignment:Splign:2.1.0"
     exon            567..662
                     /gene="Tspan33"
                     /gene_synonym="RGD1560915"
                     /inference="alignment:Splign:2.1.0"
     exon            663..791
                     /gene="Tspan33"
                     /gene_synonym="RGD1560915"
                     /inference="alignment:Splign:2.1.0"
     exon            792..953
                     /gene="Tspan33"
                     /gene_synonym="RGD1560915"
                     /inference="alignment:Splign:2.1.0"
     exon            954..1983
                     /gene="Tspan33"
                     /gene_synonym="RGD1560915"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cacgctgtcc gccgcggctt cagcggcggc gccgttctcc ggccgcgcgg ctccccgacg
       61 cacagttcgg gcggctcccg gcgcggcgcg gctgcccagg cgttcgggtc cccgtggccc
      121 cgcggctccc gcccccggct gcaggacgcg caggtgggcc ggcggccgct gggagatagg
      181 ccccccgggg gcagcagtgg accatggcgc ggagacctgg cgtgcccgct gcctacgggg
      241 aggagttctc cttcgtcagc ccgctggtga aatacctgct cttcttcttc aacatgctct
      301 tctgggtaat ttccatggtc atggtggctg tgggtgtcta tgccaggctg atgaagcacg
      361 cagaagcagc cttggcttgt ctggcggtgg accctgctat cctgctgatc gtggtgggcg
      421 ttctcatgtt ccttctcacc ttctgcggct gtatcggatc ccttcgggag aacatctgcc
      481 ttctgcagac tttctccctc tgcctcacca tcgtgttcct gctgcagctg gctgctggca
      541 tcctgggctt cgttttctca gacaaggctc gggggaaagt gagtgagatc atcaacaatg
      601 ctatcgtgca ttaccgagat gatctggatc tgcagaacct catcgacttt ggccagaaga
      661 agttcagctg ctgcggaggg atttcctaca gagactggtc tcagaatatg tacttcaact
      721 gctcggagga caaccctagc cgtgagcgct gctctgtgcc ttattcctgt tgcttgccca
      781 cccccaacca ggcagtgatc aacacaatgt gtggccaagg tatgcaggct ctggactact
      841 tggaagctag taaagtcatc tacactaacg gctgtattga caagttggtc aactggatac
      901 acagcaacct gtttctactt ggcggtgtgg cattaggcct ggccatcccc cagctggtgg
      961 gaatcctgct gtcccaggtc cttgtgaatc agataaaaga tcagatcaag ctgcagctct
     1021 acaaccagca gcaccgtgct gacccgtggt actgagactc cttcctgtgc ttcctcacca
     1081 tggtgacgag catcctcatg gaccagcagt ggagggtgct aagagcagca cccagtgcag
     1141 atttagattc cagcccccag agtgaaggcc cagtggaaag acgaaatccc aaaggaagga
     1201 cacagatggc tcaggtctca gaaggatgtg cctcatctcc ccatcccagc ctcaatactg
     1261 cctgagaatt attttgtcct gtttgtaacc ttgaacattt gagtttatgt tttttggttt
     1321 cctgtgggca gaggtgtgga agcggcagtg gtacagaaag ctgtagggtt actagctgca
     1381 cacttcgctg aggcacaaca gacagctctg ttaaggctgc tgctgagcta ggtggacata
     1441 gagtctgctg ccagggagac ctggctgtgt ggagcagaca ctagcaggcc tgcctggagt
     1501 ccagttggca taatcccagc tccagagagc aagggagtga agcaggcaga gcagagtgag
     1561 cctaggggtt ggatggggac agctgggtat atgggggata gagtggaagg gggtgtgttt
     1621 accaaatgct tgccttgctg tactcccagg tagtcagagt gagctatatc ctgcccctcc
     1681 ctcgttgcca tggaaacatg gcagcaaggg caagaagtgg ccaaattcat ccccatcccc
     1741 ctcatacagt gtttggaacc atggtcccta tattccgcat tcgggagaag ctggactaag
     1801 ccatacgtgc ccttgaattc ctctctgtct agccttcctg ccccagcaag tggggttttc
     1861 tttaacttgg cagaggagtg gcaacacctc ctacccgcat cccctgcacc agaactcagt
     1921 gtttctacag tgtaagaatc aggaatctgg cagaaatggc aataaaagtt tgttgacatg
     1981 ggc
//
