LOCUS       NM_001169127            1473 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus tetraspanin 14 (Tspan14), mRNA.
ACCESSION   NM_001169127 XM_001067025 XM_224699
VERSION     NM_001169127.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1473)
  AUTHORS   Haining,E.J., Yang,J., Bailey,R.L., Khan,K., Collier,R., Tsai,S.,
            Watson,S.P., Frampton,J., Garcia,P. and Tomlinson,M.G.
  TITLE     The TspanC8 subgroup of tetraspanins interacts with A disintegrin
            and metalloprotease 10 (ADAM10) and regulates its maturation and
            cell surface expression
  JOURNAL   J Biol Chem 287 (47), 39753-39765 (2012)
   PUBMED   23035126
REFERENCE   2  (bases 1 to 1473)
  AUTHORS   Dornier,E., Coumailleau,F., Ottavi,J.F., Moretti,J., Boucheix,C.,
            Mauduit,P., Schweisguth,F. and Rubinstein,E.
  TITLE     TspanC8 tetraspanins regulate ADAM10/Kuzbanian trafficking and
            promote Notch activation in flies and mammals
  JOURNAL   J Cell Biol 199 (3), 481-496 (2012)
   PUBMED   23091066
  REMARK    Erratum:[J Cell Biol. 2016 May 23;213(4):495-6. PMID: 27185832]
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from JAXUCZ010000016.1.
            
            On or before Dec 16, 2009 this sequence version replaced
            XM_001067025.1, XM_224699.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643292.55480.1,
                                           SRR26643297.46623.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760476,
                                           SAMN12840107 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                JAXUCZ010000016.1  16875434-16875462   c
            30-31               JAXUCZ010000016.1  16845692-16845693   c
            32-127              JAXUCZ010000016.1  16845596-16845691   c
            128-178             JAXUCZ010000016.1  16829123-16829173   c
            179-324             JAXUCZ010000016.1  16827282-16827427   c
            325-495             JAXUCZ010000016.1  16825954-16826124   c
            496-621             JAXUCZ010000016.1  16824107-16824232   c
            622-666             JAXUCZ010000016.1  16822523-16822567   c
            667-786             JAXUCZ010000016.1  16820353-16820472   c
            787-1472            JAXUCZ010000016.1  16818344-16819029   c
FEATURES             Location/Qualifiers
     source          1..1473
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p14"
     gene            1..1473
                     /gene="Tspan14"
                     /gene_synonym="RGD1305714"
                     /note="tetraspanin 14"
                     /db_xref="GeneID:306324"
                     /db_xref="RGD:1305714"
     exon            1..29
                     /gene="Tspan14"
                     /gene_synonym="RGD1305714"
                     /inference="alignment:Splign:2.1.0"
     exon            30..127
                     /gene="Tspan14"
                     /gene_synonym="RGD1305714"
                     /inference="alignment:Splign:2.1.0"
     CDS             47..859
                     /gene="Tspan14"
                     /gene_synonym="RGD1305714"
                     /codon_start=1
                     /product="tetraspanin-14"
                     /protein_id="NP_001162598.1"
                     /db_xref="GeneID:306324"
                     /db_xref="RGD:1305714"
                     /translation="MHYYRYSNAEVSCWYKYLLFSYNIVFWLAGVVFLGVGLWAWSEK
                     GVLSDLTKVTRLHGIDPVVLVLMVGVVMFTLGFAGCVGALRENICLLKFFCGAIVLIF
                     FLELAVAVLAFLFQDWVRDRFREFFESNIRSYRDDIDLQNLIDSLQKANQCCGAYGPE
                     DWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVRIQLKSKWDEFIFT
                     KGCIQALEGWLPRNIYIVAGVFIAISLLQIFGIFLARTLISDIEAVKAGHHF"
     exon            128..178
                     /gene="Tspan14"
                     /gene_synonym="RGD1305714"
                     /inference="alignment:Splign:2.1.0"
     exon            179..325
                     /gene="Tspan14"
                     /gene_synonym="RGD1305714"
                     /inference="alignment:Splign:2.1.0"
     exon            326..496
                     /gene="Tspan14"
                     /gene_synonym="RGD1305714"
                     /inference="alignment:Splign:2.1.0"
     exon            497..622
                     /gene="Tspan14"
                     /gene_synonym="RGD1305714"
                     /inference="alignment:Splign:2.1.0"
     exon            623..667
                     /gene="Tspan14"
                     /gene_synonym="RGD1305714"
                     /inference="alignment:Splign:2.1.0"
     exon            668..787
                     /gene="Tspan14"
                     /gene_synonym="RGD1305714"
                     /inference="alignment:Splign:2.1.0"
     exon            788..1473
                     /gene="Tspan14"
                     /gene_synonym="RGD1305714"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgtgctgccg ccgctgctgc cgcgcccggg tcctgcttct cggaagatgc actattacag
       61 atactcgaac gccgaggtca gctgctggta caagtacctg ctcttcagct acaatatcgt
      121 cttttggttg gctggagttg ttttccttgg agtcgggctg tgggcatgga gcgaaaaggg
      181 cgtgctgtcc gacctcacga aggtgacccg gttgcatgga atcgaccctg tcgtgctggt
      241 cttgatggtg ggcgtggtga tgttcacact gggattcgcg ggctgtgtcg gggccctgcg
      301 ggagaacatc tgcctgctca agtttttctg tggggccatt gtgctcatct tcttcctgga
      361 actggctgtg gctgtgttgg cctttttatt ccaagactgg gtgagggatc gtttccggga
      421 attcttcgag agcaacatca ggtcctatcg ggatgacatt gacctgcaga acctcattga
      481 ctctcttcag aaagccaatc agtgctgtgg ggcttacggc cctgaagact gggacctcaa
      541 tgtctacttc aactgcagtg gtgccagcta cagccgagag aaatgtgggg tgcccttctc
      601 ctgctgtgtg ccggaccctg cacaaaaagt cgtgaacaca cagtgtggct atgatgtcag
      661 gattcagctg aagagcaagt gggatgagtt catcttcacg aaggggtgca tccaggctct
      721 ggagggctgg cttcccagga acatctacat tgtggctggt gtcttcattg ccatctccct
      781 gctgcagatc ttcggcatct tcctggcaag gaccctgatc tcagacattg aggcagtgaa
      841 ggcaggccat cacttctgag gcgcaggtgc agcagatgga gctgagccac atggagaggt
      901 caagcctttc actgtccagc agcggcagaa gtcgacatta gccacctaca accagacccc
      961 agtcttccgc atcagcacga tatggcctct ctgtttcttc ttgctggtgc tgaaggccaa
     1021 ggccccttct catctgctca cacttgacat ggcacctctg aaggcccaga gacagagaat
     1081 gtgtttttat gtggagtagt aactctgagg acagatgggc tcccatggcc gcaggaaagg
     1141 cttaatggcc cttacagagc ccaagagcat ctgcaggtcc ccacctactc agtaaggctt
     1201 aggtacatgc tcagctattc tcttctgtgg gcagagcatc agtatgggac cagcattgag
     1261 gacaaggctt ctgcctccct tggatcaaga tggatggaga gggataagtg gtccagtggt
     1321 tcccctcctg tcaacaaggc tcatggtggt gcaaacgtgc caggggtttg cagaatcctc
     1381 agccatgtcc aagtgaagta tgcctgagcc agctataacc ggtcttggga agcacatcat
     1441 cactgccttc caagtctaca ctgctctccc agg
//
