LOCUS       NM_001107506            4881 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus teashirt zinc finger homeobox 3 (Tshz3), mRNA.
ACCESSION   NM_001107506 XM_001079868 XM_218516
VERSION     NM_001107506.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4881)
  AUTHORS   Caubit,X., Gubellini,P., Andrieux,J., Roubertoux,P.L., Metwaly,M.,
            Jacq,B., Fatmi,A., Had-Aissouni,L., Kwan,K.Y., Salin,P.,
            Carlier,M., Lieden,A., Rudd,E., Shinawi,M., Vincent-Delorme,C.,
            Cuisset,J.M., Lemaitre,M.P., Abderrehamane,F., Duban,B.,
            Lemaitre,J.F., Woolf,A.S., Bockenhauer,D., Severac,D., Dubois,E.,
            Zhu,Y., Sestan,N., Garratt,A.N., Lydia Kerkerian-Le,Goff. and
            Fasano,L.
  TITLE     TSHZ3 deletion causes an autism syndrome and defects in cortical
            projection neurons
  JOURNAL   Nat Genet 48 (11), 1359-1369 (2016)
   PUBMED   27668656
REFERENCE   2  (bases 1 to 4881)
  AUTHORS   Caubit,X., Thoby-Brisson,M., Voituron,N., Filippi,P., Bevengut,M.,
            Faralli,H., Zanella,S., Fortin,G., Hilaire,G. and Fasano,L.
  TITLE     Teashirt 3 regulates development of neurons involved in both
            respiratory rhythm and airflow control
  JOURNAL   J Neurosci 30 (28), 9465-9476 (2010)
   PUBMED   20631175
REFERENCE   3  (bases 1 to 4881)
  AUTHORS   Kajiwara,Y., Akram,A., Katsel,P., Haroutunian,V., Schmeidler,J.,
            Beecham,G., Haines,J.L., Pericak-Vance,M.A. and Buxbaum,J.D.
  TITLE     FE65 binds Teashirt, inhibiting expression of the primate-specific
            caspase-4
  JOURNAL   PLoS One 4 (4), e5071 (2009)
   PUBMED   19343227
REFERENCE   4  (bases 1 to 4881)
  AUTHORS   Caubit,X., Lye,C.M., Martin,E., Core,N., Long,D.A., Vola,C.,
            Jenkins,D., Garratt,A.N., Skaer,H., Woolf,A.S. and Fasano,L.
  TITLE     Teashirt 3 is necessary for ureteral smooth muscle differentiation
            downstream of SHH and BMP4
  JOURNAL   Development 135 (19), 3301-3310 (2008)
   PUBMED   18776146
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473979.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001079868.1, XM_218516.4.
            
            ##Evidence-Data-START##
            CDS exon combination :: BF567083.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA5756307, SAMEA5760383 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4881
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..4881
                     /gene="Tshz3"
                     /gene_synonym="Zfp537"
                     /note="teashirt zinc finger homeobox 3"
                     /db_xref="GeneID:308523"
                     /db_xref="RGD:1306322"
     exon            1..34
                     /gene="Tshz3"
                     /gene_synonym="Zfp537"
                     /inference="alignment:Splign:2.1.0"
     exon            35..4881
                     /gene="Tshz3"
                     /gene_synonym="Zfp537"
                     /inference="alignment:Splign:2.1.0"
     CDS             130..3246
                     /gene="Tshz3"
                     /gene_synonym="Zfp537"
                     /note="zinc finger protein 537; teashirt zinc finger
                     family member 3"
                     /codon_start=1
                     /product="teashirt homolog 3"
                     /protein_id="NP_001100976.1"
                     /db_xref="GeneID:308523"
                     /db_xref="RGD:1306322"
                     /translation="MCPEKELSKACPSYQNSPAAEFSSHEMDSESHISETSDRMADFE
                     SSSIKNEEETKEVQVPLEDTTVSDSLEQMKAVYNNFLSNSYWSNLNLNLHQPSSENNG
                     GGSSSSSSSSSSSCGSGSFDWHQSAMAKTLQQVSQNRMLPEPSLFSTVQLYRQSSKLY
                     GSIFTGASKFRCKDCSAAYDTLVELTVHMNETGHYRDDNHETDNNNPKRWSKPRKRSL
                     LEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVTPVAAKIIPAA
                     RKKPSLELELPSSPDSTGGTPKATLSDASDALQKNSNPYITPNNRYGHQNGASYAWHF
                     EARKSQILKCMECGSSHDTLQELTAHMMVTGHFIKVTNSAMKKGKPIMETPVTPTITT
                     LLDEKVQSVPLAATTFTSPSNTPASVSPKLTVEIKKEVDKEKAVLDEKPKEKEKASEE
                     EEKYDISSKYHYLTENDLEESPKGGLDILKSLENTVTSAINKAQNGTPSWGGYPSIHA
                     AYQLPNMMKLSLGSSGKSTPLKPMFGNSEIVSPTKTQTLVSPPSSQTSPMPKTNFHAM
                     EELVKKVTEKVAKVEEKMKEPDSKLSPPKRATPSPCSSEQSEPIKMEASSGSGFKSQE
                     NSPSPPRDVCKEASPSAEPVENGKELVKPLSGGSLSGSTAIITDHPPEQPFVNPLSAL
                     QSVMNIHLGKAAKPSLPALDPMSMLFKMSNSLAEKAAVATPPPLQAKKAEHLDRYFYH
                     VNNDQPIDLTKGKSDKGCSLGSGLLSPTSTSPATSSSTVTTAKTSAVVSFMSNSPLRE
                     NALSDISDMLKNLTESHTSKSSTPSSISEKSDIDGATLEEAEESTPAQKRKGRQSNWN
                     PQHLLILQAQFAASLRQTSEGKYIMSDLSPQERMHISRFTGLSMTTISHWLANVKYQL
                     RRTGGTKFLKNLDTGHPVFFCNDCASQIRTPSTYISHLESHLGFRLRDLSKLSTEQIN
                     NQIAQTKSPSEKMVTSSPEEDLGTTYQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLL
                     FVSELEKQ"
ORIGIN      
        1 aggaggaagc agcaggcgcc ccggcgcgca gcagcctatg tttccgatga gttaaaggca
       61 gctgccttgg tagaagatga catcgagcct gaggagcaag tggcggatgg agagccttca
      121 gccaagtata tgtgtccgga gaaggaactc agcaaagcct gccctagcta ccagaactca
      181 ccggccgccg agttttccag ccatgaaatg gacagcgagt ctcacatcag tgagaccagt
      241 gaccggatgg ctgacttcga aagcagttcc atcaagaatg aagaagagac caaggaggtc
      301 caggtgcccc tggaggacac caccgtgtca gatagcctgg agcagatgaa ggcggtgtac
      361 aacaacttcc tgtctaattc ctattggtcc aacctcaacc tgaacctgca ccagccctcc
      421 tccgagaaca atggtggcgg cagcagcagc agcagcagca gtagcagcag cagctgcggc
      481 agcgggagct ttgactggca ccagagtgcc atggcgaaga ccctgcagca ggtgtcgcag
      541 aaccgaatgc tacccgagcc cagcctgttc agcaccgtgc agctctaccg tcagagcagc
      601 aagctgtacg gctccatctt caccggggcc agcaagttcc ggtgcaaaga ctgtagcgcc
      661 gcctacgaca ccctggtaga gctgacggtg cacatgaatg aaacgggtca ctatcgcgat
      721 gacaaccacg agaccgacaa caacaacccc aaacgctggt ccaagcctcg caagcggtct
      781 ttgttggaga tggaggggaa ggaggatgct cagaaggtgc tgaagtgcat gtactgtggc
      841 cactccttcg agtccctcca agacctgagc gttcacatga tcaaaactaa acactaccaa
      901 aaagtgcctc tcaaggaacc tgtcacaccc gtcgcagcca aaatcatccc cgctgcccgg
      961 aagaaacctt ctctggagct cgagctgccc agctcccctg attccacggg tgggaccccc
     1021 aaagccactc tgtctgatgc cagcgatgct ctccagaaga actccaaccc ttacatcacg
     1081 ccaaataacc ggtacggcca ccagaacggg gccagctacg cgtggcactt cgaggcccgc
     1141 aagtctcaga ttctcaagtg catggagtgt ggcagctccc acgacactct ccaagagctc
     1201 acggcccaca tgatggtcac tggccacttc atcaaggtca caaactcggc catgaagaag
     1261 gggaagccca tcatggagac gcccgtcacg cccaccatca ccaccttact ggacgagaag
     1321 gtgcagtctg tgccgctggc agccaccaca ttcacatctc cctccaatac acctgccagc
     1381 gtctccccga agctgactgt ggagatcaaa aaggaagtgg acaaggagaa agccgtcctg
     1441 gatgagaaac ccaaggagaa agagaaggcc agcgaggagg aggagaagta tgatatttct
     1501 tccaagtacc actatttgac tgaaaacgac ttagaagaga gtcctaaagg gggactagat
     1561 attcttaaat ccctggagaa cacagtaaca tctgccatca ataaggctca gaatggcact
     1621 cccagctggg gcggctatcc cagcatccac gctgcctacc agctccccaa catgatgaag
     1681 ttgtccctgg gttcctcggg gaagagcaca cccctgaaac ccatgtttgg caacagcgag
     1741 atcgtgtctc ccacaaaaac ccagaccctg gtctctccgc ccagcagcca gacctccccc
     1801 atgcccaaga caaactttca cgccatggag gagctcgtga aaaaagtcac cgagaaagtt
     1861 gccaaagtcg aggagaaaat gaaagagccc gacagcaagc tgtccccacc caagcgggcc
     1921 acaccgtccc catgcagcag cgagcagagc gaacccatta agatggaggc ctccagcggc
     1981 agtggcttca aaagccagga gaacagcccc agcccaccaa gagacgtctg caaggaggcg
     2041 agcccctctg cagagccggt ggagaatggc aaggagctgg tgaagcccct gagcggggga
     2101 agcctcagcg gcagcacagc cattatcacg gaccacccac cagaacagcc ttttgtgaac
     2161 cccctgagtg ccctgcagtc ggtcatgaac atccacctgg gcaaggccgc caaaccctcc
     2221 ctgcctgcgc tggaccccat gagcatgctt ttcaagatga gcaacagtct ggccgagaag
     2281 gcagctgtgg ccaccccacc accccttcag gccaagaagg cggagcatct ggaccgctat
     2341 ttctaccacg tcaacaacga ccagcccata gacttgacaa aagggaagag cgacaaaggt
     2401 tgctctttag gttcagggct tttgtccccc acgtccacat ccccagcaac ttcctcatct
     2461 acagtgacaa cggcaaagac atctgccgtt gtatcattca tgtcaaactc gccactgcgc
     2521 gagaatgcct tgtcagatat atccgatatg ctgaagaact tgacagagag ccacacgtca
     2581 aaatcctcca ctccttccag catctctgag aagtctgaca ttgacggggc caccctggaa
     2641 gaggccgagg agtcgactcc ggcacagaag aggaaaggcc gccagtcaaa ctggaatcct
     2701 cagcacctgc taatcctgca ggcgcagttt gcagccagcc tccggcagac atcagaaggg
     2761 aagtacatca tgtcagatct gagcccccag gaacgcatgc atatctccag gttcaccggc
     2821 ctctccatga ccaccatcag tcattggctg gccaatgtga aataccagct tcgaaggaca
     2881 ggtggaacaa agttcctcaa aaacttggac actggacacc ccgtgttctt ttgtaacgac
     2941 tgtgcgtcac aaatcaggac tccttccacg tacatcagcc acctagagtc acatctgggc
     3001 ttccggctac gggacttatc aaaattgtcc accgaacaga ttaacaatca aatagcacaa
     3061 accaagtcgc catcagaaaa aatggtgaca tcctccccgg aggaggacct ggggaccacc
     3121 tatcagtgca agctttgtaa tcggaccttt gcgagcaagc atgctgtcaa acttcacctt
     3181 agcaaaacac acgggaaatc gccggaagac cacctcctgt tcgtttctga gctggagaag
     3241 cagtagcaat tgctccagag tggaaatgac tggaggaaaa aaatgctgaa ggcaccttaa
     3301 agcccctctg tcttgttctt ggcacatgtt cttatagtca cagcagagga tcgttctggg
     3361 ctggactgtc tggtataact gtacagtgtt taatagagag gtgcatataa tcagctgttg
     3421 ttactggtaa aataacaaag gttaaaacgc agtgctaagt gtttggaact ttgtgtaaat
     3481 gggatttaat tgtgagcatc ccccctgatg cttcaagctg catgcattaa cagacggttt
     3541 aattaagcat ttataaggaa accaggcaca ctttttccac gagacttggg tgcgctggca
     3601 tttcccgccc ccttcatctt tagccctctg agtactacga agcacttttg cattaatttg
     3661 gttaataaaa ataaaagata ataataaaac aaaataataa tgaagaataa taataatgta
     3721 tgaaactctg tttttaaact ccttaccagc ttagttataa gggaatatta ggagcctccg
     3781 tttatgcagg ggtatgacac gccttgaaat ttaaaagaat attattttca cattgaaaca
     3841 tagatgtata tattgtatag atttcgaact cttatgggaa aatgtgactg gttaaatgac
     3901 cctttctttc ttgcatttat aacaagtgtt ttatgtactt gctatactct gggcacaagc
     3961 catgcctctg tatagtgtat atttccttat ctttttccct ttttttttta aggtttatgt
     4021 ttttttttta catgcaaacg ttgtaaatta tacagaaaaa aaataccaca gatagcattt
     4081 ataaaatata cagaagcatt atctcaaagc aaggtatgat gtttgttttg ctatacggca
     4141 cttctatatt gatagagggt tcatgtttaa attatacata tttattagca ttctattatc
     4201 attttgtttt gaggccagga aatccatccc tggtaggcat cataactatt ttgcacatgg
     4261 ttcttaaagg tatttattag agattaaagg atgctcaaag taaactcagt gctcaaaggg
     4321 ttaagtctat tcgaaaaagg aaaaaaaaag atttaaaaaa aaaagaaaaa acaacttgta
     4381 ctgtatttcc tgaacgttga taaagccttt aaaatgtttg tactgtaacc ctttgcttca
     4441 aggtcatgag gcgttctgtg ggacaacctc cgtcatttat ttataagccc tctcggttgc
     4501 tagttcacaa tgtgggattt ttttcttctt tctttctttt tccttctcct tttttttttt
     4561 ttttttaatt tcaatcggta actttgtttt gttcctccta attattctcc caagatccca
     4621 cactgcagtt ttatctttag gcttatgaaa ggtaacccgt ggttaccagc tctccaagcc
     4681 attctggtct ctccatttct ggcagttaat ttgcagaaat aactgacagc tgacaccata
     4741 tgagaaccta tgtataaaat attggcatgt aaacaccaca gacaccgtga cacactccgt
     4801 gccctgtttt gttgttgacg atggcacacc atgatgtgac tcttcatata accctttttt
     4861 tctacggcag cattaaaatt g
//
