LOCUS       NM_001276476            1168 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Rattus norvegicus Ts translation elongation factor, mitochondrial
            (Tsfm), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001276476 XM_001054607 XM_003750327
VERSION     NM_001276476.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1168)
  AUTHORS   Emperador,S., Bayona-Bafaluy,M.P., Fernandez-Marmiesse,A.,
            Pineda,M., Felgueroso,B., Lopez-Gallardo,E., Artuch,R., Roca,I.,
            Ruiz-Pesini,E., Couce,M.L. and Montoya,J.
  TITLE     Molecular-genetic characterization and rescue of a TSFM mutation
            causing childhood-onset ataxia and nonobstructive cardiomyopathy
  JOURNAL   Eur J Hum Genet 25 (1), 153-156 (2016)
   PUBMED   27677415
REFERENCE   2  (bases 1 to 1168)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 1168)
  AUTHORS   Zibara,K., Bourdillon,M.C., Chignier,E., Covacho,C. and
            McGregor,J.L.
  TITLE     Identification and cloning of a new gene (2A3-2), homologous to
            human translational elongation factor, upregulated in a
            proliferating rat smooth muscle cell line and in carotid
            hyperplasia
  JOURNAL   Arterioscler Thromb Vasc Biol 19 (7), 1650-1657 (1999)
   PUBMED   10397682
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from FQ220263.1.
            
            On or before Feb 17, 2013 this sequence version replaced
            XM_001054607.3, XM_003750327.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ220263.1, CO397225.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1168              FQ220263.1         1-1168
FEATURES             Location/Qualifiers
     source          1..1168
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q22"
     gene            1..1168
                     /gene="Tsfm"
                     /gene_synonym="2A3-2; EF-Ts; EF-TsMt"
                     /note="Ts translation elongation factor, mitochondrial"
                     /db_xref="GeneID:679068"
                     /db_xref="RGD:1593058"
     exon            1..60
                     /gene="Tsfm"
                     /gene_synonym="2A3-2; EF-Ts; EF-TsMt"
                     /inference="alignment:Splign:2.1.0"
     CDS             7..981
                     /gene="Tsfm"
                     /gene_synonym="2A3-2; EF-Ts; EF-TsMt"
                     /note="elongation factor Ts, mitochondrial"
                     /codon_start=1
                     /product="elongation factor Ts, mitochondrial precursor"
                     /protein_id="NP_001263405.1"
                     /db_xref="GeneID:679068"
                     /db_xref="RGD:1593058"
                     /translation="MSLLRSLRFFPVACTGRPARAVLLQPSQPWHTLHAGPSLSSSAS
                     SKELLMKLRRTTGYSFVNCKKALETCGGDLKQAEAWLHKQAQKEGWSKAAKLHGRKTK
                     EGLIGLLQEENTAVLVEVNCETDFVSRNVKFQQLVQQVALGTMAHCQNLTDQLSTYSK
                     GFLNSSELSELAAGPDGEGSLKDQLALAIGTLGENMSLKRAAWVKVPSGFYVGSYVHG
                     EMQSPSLQNLVLGKYGALVICQTPEQITNLEEVGRRLGQHVVGMAPLSVGSLDDEPGG
                     ETETRMLPQPYLLDPSITLGQYVQPQGVTVVDFVRFECGEGEQVAEAE"
     exon            61..234
                     /gene="Tsfm"
                     /gene_synonym="2A3-2; EF-Ts; EF-TsMt"
                     /inference="alignment:Splign:2.1.0"
     exon            235..363
                     /gene="Tsfm"
                     /gene_synonym="2A3-2; EF-Ts; EF-TsMt"
                     /inference="alignment:Splign:2.1.0"
     exon            364..486
                     /gene="Tsfm"
                     /gene_synonym="2A3-2; EF-Ts; EF-TsMt"
                     /inference="alignment:Splign:2.1.0"
     exon            487..574
                     /gene="Tsfm"
                     /gene_synonym="2A3-2; EF-Ts; EF-TsMt"
                     /inference="alignment:Splign:2.1.0"
     exon            575..1149
                     /gene="Tsfm"
                     /gene_synonym="2A3-2; EF-Ts; EF-TsMt"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acagggatgt cgctgctgcg gtcgctgcgc ttcttcccgg tcgcgtgtac cggccgcccg
       61 gcaagggctg tcctgctcca gccgtcccag ccatggcaca cgcttcacgc gggcccctcg
      121 ttgtcgtctt ctgcctccag caaggagctc ctcatgaagc tgcggcggac aacaggctac
      181 tcctttgtca actgcaagaa ggctctggag acttgtggcg gggatctcaa gcaggcagag
      241 gcctggctgc acaaacaggc ccagaaggaa ggatggagca aagccgccaa gctccatggg
      301 agaaagacta aagaaggctt gattggcctg ctgcaggagg aaaacacagc tgttttagta
      361 gaggtaaact gcgagacaga tttcgtctcc agaaatgtaa aatttcaaca gttggtccag
      421 caagtagccc tgggaaccat ggcacactgt cagaacctga cggatcagct ctccacgtac
      481 agtaagggct tcctcaactc ctctgagctt tctgaacttg cagctgggcc cgacggggaa
      541 gggtctctca aggaccagtt ggccttagcg attgggacac tgggagaaaa catgagtctt
      601 aagcgagctg cctgggtgaa ggtgccctct gggttctatg tcggctctta tgtgcacgga
      661 gagatgcaga gcccctccct ccagaacctg gtgctgggga agtacggggc cctggtcatc
      721 tgccagactc ctgagcagat cacaaacctg gaggaggttg gccgccgctt gggacagcat
      781 gtggtgggca tggcccctct ctcagtgggc tccctggatg atgagcctgg aggggagaca
      841 gagacccgga tgctgcccca gccatatctc ctggatcctt ccatcacact ggggcagtat
      901 gtgcagcccc agggggtgac cgtagtcgac tttgtgcgct tcgaatgtgg agaaggtgag
      961 caggtagcag aggctgaata ggtggaaata tttaattttc atacctggat ttccttataa
     1021 aaagttattt tttaaacctt ttcaaccctc agattttttt tttagtttaa aatgaagtta
     1081 tatattcatg ggtaaagtta ttaaatatca atgtaataaa gcatgatcat ttatttgcat
     1141 aatacttaaa aaaaaaaaaa aaaaaaaa
//
