LOCUS       NM_001012173            1722 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Rattus norvegicus TruB pseudouridine synthase family member 1
            (Trub1), mRNA.
ACCESSION   NM_001012173 XM_342069
VERSION     NM_001012173.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1722)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 1722)
  AUTHORS   Safra,M., Nir,R., Farouq,D., Vainberg Slutskin,I. and Schwartz,S.
  TITLE     TRUB1 is the predominant pseudouridine synthase acting on mammalian
            mRNA via a predictable and conserved code
  JOURNAL   Genome Res 27 (3), 393-406 (2017)
   PUBMED   28073919
  REMARK    Erratum:[Genome Res. 2017 Aug;27(8):1460. doi:
            10.1101/gr.225870.117.. PMID: 28765290]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC087683.1.
            
            On Feb 11, 2005 this sequence version replaced XM_342069.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087683.1, CV077025.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1722
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q55"
     gene            1..1722
                     /gene="Trub1"
                     /note="TruB pseudouridine synthase family member 1"
                     /db_xref="GeneID:361775"
                     /db_xref="RGD:1308502"
     exon            1..276
                     /gene="Trub1"
                     /inference="alignment:Splign:2.1.0"
     CDS             18..1043
                     /gene="Trub1"
                     /EC_number="5.4.99.25"
                     /note="probable tRNA pseudouridine synthase 1; TruB
                     pseudouridine (psi) synthase homolog 1; TruB pseudouridine
                     (psi) synthase family member 1; psi55 synthase TRUB1; tRNA
                     pseudouridine 55 synthase TRUB1; truB pseudouridine
                     synthase homolog 1"
                     /codon_start=1
                     /product="pseudouridylate synthase TRUB1"
                     /protein_id="NP_001012173.1"
                     /db_xref="GeneID:361775"
                     /db_xref="RGD:1308502"
                     /translation="MAAEEAEVVSPLIVDTAPDTSGTAAASLAAAVSAAAAAARTGSQ
                     AQVSKAALAAKLMSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGLPSPEWNKRQKQT
                     LKVGHGGTLDSAAQGVLVVGIGRGTKMLTSMLSGSKRYIATGELGKATDTLDSTGKVT
                     EEKPYDKITQEDIEGILQKFTGNIMQVPPLYSALKKDGQRLSTLMKRGETVEARPARP
                     VTVHSISLLKYQPPFFTLDVECGGGFYIRSLVSDIGKELSSCATVLELTRTKQGPFTL
                     AQHALPEDRWTINDIAQSLKRCTSLLPEELTFKKSKSEPSSDQALSCGYITLRETKRE
                     DDTVKTL"
     exon            277..375
                     /gene="Trub1"
                     /inference="alignment:Splign:2.1.0"
     exon            376..431
                     /gene="Trub1"
                     /inference="alignment:Splign:2.1.0"
     exon            432..513
                     /gene="Trub1"
                     /inference="alignment:Splign:2.1.0"
     exon            514..586
                     /gene="Trub1"
                     /inference="alignment:Splign:2.1.0"
     exon            587..726
                     /gene="Trub1"
                     /inference="alignment:Splign:2.1.0"
     exon            727..783
                     /gene="Trub1"
                     /inference="alignment:Splign:2.1.0"
     exon            784..1695
                     /gene="Trub1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtccaggccg tgaaagcatg gcagctgagg aggccgaggt ggtttcacct ctgattgtgg
       61 acacagcccc agacacttca ggaacagccg cggcctcact agccgcagcg gtgtctgctg
      121 ctgcggcagc ggctaggact ggatcgcaag cccaggtttc caaggccgct ctggctgcta
      181 agctcatgtc gctcagcggc gtgttcgccg tgcacaagcc caaagggccc acttcagccg
      241 agctgctgaa ccggctgaag gagaagctgc tggcagaagc tggattgcca tctccagaat
      301 ggaacaagag gcaaaagcag acattgaaag ttggacacgg agggacactg gacagcgcag
      361 cgcaaggtgt tctggtggtt gggattggaa gaggaacaaa aatgttgacc agtatgttgt
      421 cggggtccaa gaggtatatc gccactggag aactggggaa agccacggac acactggatt
      481 ctaccgggaa ggtaacagag gagaagccat atgataaaat aacacaagaa gatatcgaag
      541 gcattctgca gaagtttact gggaatataa tgcaagtacc ccccctctat tctgcactga
      601 agaaggatgg acagagactc tcaacgttaa tgaagagagg cgagactgtt gaggccaggc
      661 cagccaggcc agtgactgtt cacagcatct ccctcctgaa gtaccagcca ccgttcttca
      721 cgctagatgt tgaatgtgga ggaggctttt acatccgaag cttggtcagt gacattggca
      781 aagaactctc ttcctgtgcc accgtgctgg agctgacccg caccaaacag gggcccttta
      841 cactggcaca gcatgcgctc cccgaagaca gatggaccat caatgacatc gcacagtccc
      901 tcaagcgctg cacgtccctt ctgccagagg agctgacgtt taaaaaatcc aaatccgagc
      961 cgtccagtga ccaggcctta agctgtgggt acataactct aagggagaca aagagagaag
     1021 acgacacagt taagacgctt tgagcccggc cggggaggat catttccggg ttggtgtata
     1081 tcctgacctg acccaggaat gcccacacac ttcttcaggt ctttgcaaga tgtcgtaatg
     1141 tctctgaatg atggatatga ctggattcag ataaataagt tttctgaatt tgatcttccc
     1201 ttagtctttt tcctgtgaaa aagttgaaca gaattctagt cacagaggac tgaggtctga
     1261 gctgcaagtc ccacagaggt atcatatcca ctctgtcaga ctgggggagg gcgctcattg
     1321 ttctgaaatc ctcttaatat tcgaagtgct cagtgctgag ccatcccgtc ctgtgtgttt
     1381 gcagagctgt ggctgctggg aagcgctggt gggctgaagt catctgtgac tgtgtttctt
     1441 agatcttgaa atgaaacgtt tccctaataa atatttgtaa gtgcacaaac tcctgctccg
     1501 accactggca gagtggaaat agctgaagag gtgattcatt ccatccctat tttcagcaga
     1561 gttcggctcc tggagctgtg tactctgtgg cagctatttc tgtggtcagc cacatggtgt
     1621 caagttacta aaaagggatc tttcagaata taaactaaag gatgtatctt gaattaaaat
     1681 tctctgctgc ccgttaaaaa aaaaaaaaaa aaaaaaaaaa aa
//
