LOCUS       NM_001106331            2882 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus tRNA phosphotransferase 1 (Trpt1), mRNA.
ACCESSION   NM_001106331 XM_001076425 XM_219539
VERSION     NM_001106331.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2882)
  AUTHORS   Harding HP, Lackey JG, Hsu HC, Zhang Y, Deng J, Xu RM, Damha MJ and
            Ron D.
  TITLE     An intact unfolded protein response in Trpt1 knockout mice reveals
            phylogenic divergence in pathways for RNA ligation
  JOURNAL   RNA 14 (2), 225-232 (2008)
   PUBMED   18094117
REFERENCE   2  (bases 1 to 2882)
  AUTHORS   Spinelli SL, Malik HS, Consaul SA and Phizicky EM.
  TITLE     A functional homolog of a yeast tRNA splicing enzyme is conserved
            in higher eukaryotes and in Escherichia coli
  JOURNAL   Proc Natl Acad Sci U S A 95 (24), 14136-14141 (1998)
   PUBMED   9826666
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473953.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_219539.4, XM_001076425.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2882
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..2882
                     /gene="Trpt1"
                     /gene_synonym="Tpt1h"
                     /note="tRNA phosphotransferase 1"
                     /db_xref="GeneID:293704"
                     /db_xref="RGD:1310831"
     exon            1..391
                     /gene="Trpt1"
                     /gene_synonym="Tpt1h"
                     /inference="alignment:Splign:2.1.0"
     CDS             332..1078
                     /gene="Trpt1"
                     /gene_synonym="Tpt1h"
                     /EC_number="2.7.1.160"
                     /note="tRNA splicing 2' phosphotransferase 1 homolog"
                     /codon_start=1
                     /product="tRNA 2'-phosphotransferase 1"
                     /protein_id="NP_001099801.1"
                     /db_xref="GeneID:293704"
                     /db_xref="RGD:1310831"
                     /translation="MNAPGGRRQEGRRTHRPREQDRNVQLSKALSYALRHGALKLGLP
                     MRADGFVPLQALLQLPQFHSFSIEDVQLVVDTNEKQRFTLQPGEPSTGPLIRANQGHS
                     LQVPELELMPLETPQALPSTLVHGTFWKHWPSILLNGLSRQGRTHIHLASGLPGDSGV
                     ISGIRPNCEVAVFINGALALTDGIPFFCSVNGVILTPGNADGFLLPKYFKEALQLRPT
                     RKPLSLTGDKETESQSGPKHSSRGGRRKIQ"
     exon            392..473
                     /gene="Trpt1"
                     /gene_synonym="Tpt1h"
                     /inference="alignment:Splign:2.1.0"
     exon            474..643
                     /gene="Trpt1"
                     /gene_synonym="Tpt1h"
                     /inference="alignment:Splign:2.1.0"
     exon            644..818
                     /gene="Trpt1"
                     /gene_synonym="Tpt1h"
                     /inference="alignment:Splign:2.1.0"
     exon            819..875
                     /gene="Trpt1"
                     /gene_synonym="Tpt1h"
                     /inference="alignment:Splign:2.1.0"
     exon            876..986
                     /gene="Trpt1"
                     /gene_synonym="Tpt1h"
                     /inference="alignment:Splign:2.1.0"
     exon            987..2882
                     /gene="Trpt1"
                     /gene_synonym="Tpt1h"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtggcttccc attggccagt ccgtgtccag gggcggggcc cgccctccgc agttgagcgc
       61 gtcggatcta cggcggcctg gctcttctcc gtgtcaatcc gcacgccagc ccggtccccc
      121 ggggcagtgc tgcgatctga tttcaggaca ttgggtttgt tccggatccc tcgagcctcg
      181 aggctgcctg tgtgaccttg agcaagtctc gcccgctggg cctcaagttc ccttgtgtac
      241 tagggtggga tgagcagtgt ggttcttatc ctgagttttt gtaactttct tggtggagaa
      301 cccacctccc tgctccctac aggtcttggt catgaacgcc cccggaggaa ggaggcagga
      361 aggtagaagg actcatagac cgcgggaaca ggacagaaat gtgcagctgt ctaaggctct
      421 gtcctatgcc cttcgccacg gggccttgaa gctgggactt cccatgcgag ctgatggctt
      481 tgtgcccctg caagccctcc tgcagctgcc ccagttccac agcttctcaa ttgaggatgt
      541 gcagctcgtg gtggacacca atgaaaagca gcggtttacc ctgcagccag gcgagcccag
      601 cactgggccc ctcatcaggg ccaatcaggg tcactcccta caagtccctg agttggaact
      661 gatgcccctg gagacaccac aagccctgcc ctcgacacta gtccatggta cattctggaa
      721 gcactggcca tctattctac tgaatggcct gtcacgccaa ggaaggacac acatccactt
      781 agcctcgggg ttgcctgggg actctggtgt catcagtggc attcgtccaa attgtgaagt
      841 ggcagtgttc atcaatggag ccctagccct cacagatgga atccctttct tctgctctgt
      901 caacggagtg atcctgactc cagggaatgc ggacggtttc ctgcttccca agtacttcaa
      961 ggaggccctg cagctgcgac ctacccgaaa gcctctctcc ttgactggtg ataaagagac
     1021 agagtctcag agtggcccca agcacagctc cagaggagga agaagaaaga tccaataata
     1081 aaatatttat ttattaaaaa aaacctgaaa cacgcaaaaa gaaagtccag cttcaaacca
     1141 ggatttcctg ttccttatcc atatttggca ttcatcatgt gcttagagac tacatatagg
     1201 tcaagggtgt gagcttgtgc caatagggca agaggagggg cttcgtgtgg ctcagggccc
     1261 atcgtcccta ggctgggtgg tggtagcatc taccccagtg agggccctgg cctacctgag
     1321 gacaagtgag ggtgcccagc agggtgcatg ctgggagagt tcaggtgggc gtggccatgg
     1381 gagagtccct ggagggtgtg ggtagagcag gggctgtctt tagaaggcct catgccctcc
     1441 agtaagctgt aggaacagat cctcgtccag ctcctcccct cgggcccgct ctcgagtgga
     1501 caggaaaatg tagcccccga tgtactcgtg cacgatgcgg cagctagcag acacacagct
     1561 gaaggccaca ttgatatgtt catcgaactc aatggccacc tgcaagtggg ttgtcacagg
     1621 tccagtgggg tggggcagca agcagcagcc tctggcctgc cctggttggg tctgagctgg
     1681 ttacctgccc ctgcccttcc tggcctacct gccgtatgtc ccagttgacg ttccattgcc
     1741 gcatgttgct gaagcgccag gtcttgacca cgtcacccac ggccagatca attcggatca
     1801 gtcggttgtt ggcgatgccc agaatctcat ccttcctgct gcccttgaac ctgatttcca
     1861 gggagaaaga acatgagtga aagctacact gtaacggccc tggaacccac cccatgtgtc
     1921 tattgctgca gggccctctg ctctgccgct gctcagcctg aggcagtcag cttcttagtc
     1981 ttaagctcct acgttgaaaa aaaaatggca ttatttctgg gcttatgcta gccaggcatg
     2041 gtactgtagg tctgtcatcc cagcaaaggg gctgaggcag gatttcacat cggactccat
     2101 acatggcgaa agaagctctg tctctaaaac gggaagcgct gggacgcgcc taagtgaata
     2161 aagcacttgc cttgcactta caaaggccca gtgtgttcct ttagacccca ggagtgcgtg
     2221 cttctgaccc ctggggtcta ttagccggcc agccaaccct accgtgtgaa ttccaggcca
     2281 ataggagata atggtctcaa aaacagggta gacaagttgg gaggagagat ttctcagtgg
     2341 ataaagccct ttcatgtgtg aaaatacaga acccttccaa atctaatgca tcatagtgtg
     2401 cctacagcaa aatggaaggc agagattgca ggccagccag cctggaatac atagtatcag
     2461 aactcttatc tcaaacaagg taggggctgg agagatggct cggaggttaa gagcaccgac
     2521 tgctcttcta gaggtcctga gttcaattcc cagcaaccac atggtggctc gcaaccatct
     2581 gtagtgagat ctgatgccct cttccactgt gtctgaagac agctacagtg tacttaacat
     2641 agaataaatg aataaatcaa aaaattaaaa taagagcatt aagaaaaaat atgggtgtgg
     2701 gtgtggagag atggctcagc agtaagaaca ctggctgctc ttgcagagga tccagttacg
     2761 tttccagcac ccccatgtca gctcacaata ggggtctcca acgccttctg gcctccaagg
     2821 gcaccatgga cacacaaggt gcacagacac acacacacac tcatatacaa ataagaataa
     2881 ag
//
