LOCUS       NM_001007706            1863 bp    mRNA    linear   ROD 26-OCT-2024
DEFINITION  Rattus norvegicus tRNA methyltransferase 61A (Trmt61a), transcript
            variant 1, mRNA.
ACCESSION   NM_001007706 XM_234552
VERSION     NM_001007706.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1863)
  AUTHORS   Li,X., Xiong,X., Zhang,M., Wang,K., Chen,Y., Zhou,J., Mao,Y.,
            Lv,J., Yi,D., Chen,X.W., Wang,C., Qian,S.B. and Yi,C.
  TITLE     Base-Resolution Mapping Reveals Distinct m1A Methylome in Nuclear-
            and Mitochondrial-Encoded Transcripts
  JOURNAL   Mol Cell 68 (5), 993-1005 (2017)
   PUBMED   29107537
REFERENCE   2  (bases 1 to 1863)
  AUTHORS   Safra,M., Sas-Chen,A., Nir,R., Winkler,R., Nachshon,A.,
            Bar-Yaacov,D., Erlacher,M., Rossmanith,W., Stern-Ginossar,N. and
            Schwartz,S.
  TITLE     The m1A landscape on cytosolic and mitochondrial mRNA at
            single-base resolution
  JOURNAL   Nature 551 (7679), 251-255 (2017)
   PUBMED   29072297
REFERENCE   3  (bases 1 to 1863)
  AUTHORS   Ozanick,S., Krecic,A., Andersland,J. and Anderson,J.T.
  TITLE     The bipartite structure of the tRNA m1A58 methyltransferase from S.
            cerevisiae is conserved in humans
  JOURNAL   RNA 11 (8), 1281-1290 (2005)
   PUBMED   16043508
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC079198.1.
            
            On Nov 29, 2004 this sequence version replaced XM_234552.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079198.1, CK596541.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1863
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q32"
     gene            1..1863
                     /gene="Trmt61a"
                     /gene_synonym="Gcd14; RGD1359191; Trm61"
                     /note="tRNA methyltransferase 61A"
                     /db_xref="GeneID:314462"
                     /db_xref="RGD:1359191"
     exon            1..34
                     /gene="Trmt61a"
                     /gene_synonym="Gcd14; RGD1359191; Trm61"
                     /inference="alignment:Splign:2.1.0"
     exon            35..394
                     /gene="Trmt61a"
                     /gene_synonym="Gcd14; RGD1359191; Trm61"
                     /inference="alignment:Splign:2.1.0"
     CDS             64..936
                     /gene="Trmt61a"
                     /gene_synonym="Gcd14; RGD1359191; Trm61"
                     /EC_number="2.1.1.220"
                     /note="tRNA(m1A58)-methyltransferase subunit TRM61; tRNA
                     (adenine-N(1)-)-methyltransferase catalytic subunit TRM61;
                     tRNA(m1A58)MTase subunit TRM61; tRNA
                     (adenine-N(1)-)-methyltransferase catalytic subunit
                     TRMT61A; tRNA(m1A58)MTase subunit TRMT61A;
                     tRNA(m1A58)-methyltransferase subunit TRMT61A; GCD14 and
                     PCMT domain containing protein RGD1359191; GCD14/PCMT
                     domain containing protein RGD1359191; tRNA
                     methyltransferase 61 homolog A; mRNA
                     methyladenosine-N(1)-methyltransferase catalytic subunit
                     TRMT61A"
                     /codon_start=1
                     /product="tRNA (adenine(58)-N(1))-methyltransferase
                     catalytic subunit TRMT61A"
                     /protein_id="NP_001007707.1"
                     /db_xref="GeneID:314462"
                     /db_xref="RGD:1359191"
                     /translation="MSFVAYEELIKEGDTAILSLGHGSMVAVRVQRGAQTQTRHGVLR
                     HSVDLIGRPFGSKVTCSRGGWVYVLHPTPELWTVNLPHRTQILYSTDIALITMMLELR
                     PGSVVCESGTGSGSVSHAIIRSIAPTGHLHTVEFHQQRADKAREEFQQHRVSQWVTVH
                     TQDVCRSGFGVVHVADAVFLDIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQ
                     ALAAHGFTELSTLEVLPQVYNVRTVSLPLPDLGADDLEGNVGSDATPFRSGTPMKETV
                     GHTGYLTFATKTPG"
     exon            395..661
                     /gene="Trmt61a"
                     /gene_synonym="Gcd14; RGD1359191; Trm61"
                     /inference="alignment:Splign:2.1.0"
     exon            662..1834
                     /gene="Trmt61a"
                     /gene_synonym="Gcd14; RGD1359191; Trm61"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacacgtgta gatcggagag ccggtttatg ctgcgtccct gattcttggc aaatgttaac
       61 accatgagtt tcgtggcata cgaggagctg atcaaggaag gcgacacagc catcctgtca
      121 ctgggccatg gctcgatggt ggcagtgcgt gtgcagcgtg gggcacagac ccagacccgg
      181 catggcgtcc tgcggcactc agtggacctc attgggcgtc catttggctc caaggtgact
      241 tgcagcagag gcggctgggt gtatgtgctg caccctactc ccgagctctg gacggtgaac
      301 ctgccccacc gcacacagat cctctactct accgacattg ccttaatcac catgatgctg
      361 gagctgcggc ccggttctgt ggtctgtgaa tcaggcacgg gcagcggttc cgtgtcccac
      421 gcgatcatcc gcagtatcgc ccccacgggc cacctacaca cggtagaatt ccaccagcag
      481 cgggcagaca aggcccggga ggagttccag cagcatcggg tgagccagtg ggtgactgtg
      541 cacactcagg atgtgtgccg gagtggcttc ggtgtggttc acgtggctga cgccgtcttc
      601 ttggatatcc catcaccctg ggaagctgtg ggccatgcct gggatgccct caaggttgaa
      661 ggtgggcgct tctgctcctt ctcgccgtgc attgaacagg tgcagcgcac atgccaggcc
      721 ctggcagccc atggcttcac agagctcagc accctggagg tgctgccaca ggtctacaat
      781 gtgcgcactg tcagtctgcc cttgcctgac ctgggggccg acgacttaga gggcaacgtg
      841 ggctctgatg ccaccccctt ccgtagtggc acacccatga aggagactgt gggccacact
      901 ggctacctca cttttgccac caagacccca ggctagtggg cctccaaagg aatatcggag
      961 gccagccgga ggccagaggc tgccttatat ggtcagccac tgcgtttaga aagagatggg
     1021 ggaggggcct cctgggtggt tggggaatag gctggcccgc tcagttggga ggcactcctg
     1081 tcttctgaga gggaacctcc gcttcctcac tgcccagctc aagcgcagcc cctgctcttt
     1141 gttgtcaaca tgaagtttcc cctccacagc tttcctgggt tttgggacca aatggtacaa
     1201 cttgagagca gcagaagctt ggggcactgt ctgaagcccc agctgaccta caggagcaac
     1261 ggactatccc atccctggtc caaggctcca gcccctggtg gtccagagct tagccagaag
     1321 ctgtggttga gctaagctca gaaagctggg cctatattca tcttcctata cctccctgag
     1381 gctgatggag ggaccaggcc agcttaggat caaaggacgt gactccataa tcttgtgctg
     1441 cacaggccct gtgtgagcgt gcccgtgtga gcgcgcccgt gagctcctga tgtgctgtca
     1501 cctgaggtta ggcggcatcc tgtggagatg gcatgcagca ggttaggtcc atgcttccag
     1561 tggcctgtca agcccttgtt ggagctaggg tcaaagagca ggtcatagag gaggccatca
     1621 tgtgctaaga gccctgtcta tggacttgct gcatgtgtca ccttggtgtc cattcccacc
     1681 cagtatgtgg ctggcttcac gggagtttca tattggtgcg aggctgccct gtagctgctg
     1741 gtgatgtgtg aaaccagcca ctgagagact taaccatgtc atatgtcata cctgacatta
     1801 cctagaggag caataaatgt tttaccccac tgtgaaaaaa aaaaaaaaaa aaaaaaaaaa
     1861 aaa
//
