LOCUS       NM_198051               1563 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus tRNA methyltransferase 11 homolog (Trmt11), mRNA.
ACCESSION   NM_198051
VERSION     NM_198051.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1563)
  AUTHORS   Purushothaman,S.K., Bujnicki,J.M., Grosjean,H. and Lapeyre,B.
  TITLE     Trm11p and Trm112p are both required for the formation of
            2-methylguanosine at position 10 in yeast tRNA
  JOURNAL   Mol Cell Biol 25 (11), 4359-4370 (2005)
   PUBMED   15899842
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1 and AF532978.1.
            
            [WARNING] On Apr 25, 2024 this sequence was replaced by
            NM_198051.3.
            
            On Dec 7, 2020 this sequence version replaced NM_198051.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF532978.1, SRR26643294.299.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 5' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-110               JAXUCZ010000001.1  28873361-28873470
            111-165             JAXUCZ010000001.1  28877821-28877875
            166-176             AF532978.1         171-181
            177-250             JAXUCZ010000001.1  28881989-28882062
            251-332             JAXUCZ010000001.1  28884437-28884518
            333-425             JAXUCZ010000001.1  28884607-28884699
            426-560             JAXUCZ010000001.1  28884951-28885085
            561-717             JAXUCZ010000001.1  28886227-28886383
            718-798             JAXUCZ010000001.1  28898605-28898685
            799-963             JAXUCZ010000001.1  28901946-28902110
            964-1036            JAXUCZ010000001.1  28903664-28903736
            1037-1168           JAXUCZ010000001.1  28903850-28903981
            1169-1289           JAXUCZ010000001.1  28912824-28912944
            1290-1563           JAXUCZ010000001.1  28928406-28928679
FEATURES             Location/Qualifiers
     source          1..1563
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p11"
     gene            1..1563
                     /gene="Trmt11"
                     /gene_synonym="Mds024"
                     /note="tRNA methyltransferase 11 homolog"
                     /db_xref="GeneID:378794"
                     /db_xref="RGD:727798"
     exon            1..110
                     /gene="Trmt11"
                     /gene_synonym="Mds024"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..1430
                     /gene="Trmt11"
                     /gene_synonym="Mds024"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; putative RNA methylase MDS024"
                     /codon_start=1
                     /product="tRNA (guanine(10)-N2)-methyltransferase homolog"
                     /protein_id="NP_932168.2"
                     /db_xref="GeneID:378794"
                     /db_xref="RGD:727798"
                     /translation="MALPGSLNRYLLLMAQEHLEFRLPEITSLLSLFGGQFTSSQETY
                     GKSPFWILNIPSEDIARNLMKRTVCAKSLFELWGHGKSPEELYSSLKSYPVEKMVPFL
                     HSDSTYKIKIHTFNKTLTQEEKVERIDALEFLPFEGKVNLKKPQHVFSILEDYGLDPN
                     CIPENPHNIYFGRWIADGQRELIESYSVKKRHFIGNTSMDAGLSFIMANHAKVKENDL
                     VFDPFVGTGGLLIASAHFGAYVCGTDIDYNTVHGLGKASRKNQKWRGPDENIRANLRQ
                     YGLEKFYLDVLVSDASKPSWRKGTYFDAIITDPPYGIRESTRRTGSQKEILKGIEKCP
                     ESHVPVSLTYHLSDMFLDLINFAAETLVLGGRLVYWLPVYTPEYTEKMVPWHPCLRLV
                     SNCEQKLSSHTARRLITMEKVKEFENPDEYSRLLSDHFLPYQGHNSFREKYFSGVTKR
                     IATEEQCSHEGKL"
     exon            111..176
                     /gene="Trmt11"
                     /gene_synonym="Mds024"
                     /inference="alignment:Splign:2.1.0"
     exon            177..250
                     /gene="Trmt11"
                     /gene_synonym="Mds024"
                     /inference="alignment:Splign:2.1.0"
     exon            251..332
                     /gene="Trmt11"
                     /gene_synonym="Mds024"
                     /inference="alignment:Splign:2.1.0"
     exon            333..425
                     /gene="Trmt11"
                     /gene_synonym="Mds024"
                     /inference="alignment:Splign:2.1.0"
     exon            426..560
                     /gene="Trmt11"
                     /gene_synonym="Mds024"
                     /inference="alignment:Splign:2.1.0"
     exon            561..717
                     /gene="Trmt11"
                     /gene_synonym="Mds024"
                     /inference="alignment:Splign:2.1.0"
     exon            718..798
                     /gene="Trmt11"
                     /gene_synonym="Mds024"
                     /inference="alignment:Splign:2.1.0"
     exon            799..963
                     /gene="Trmt11"
                     /gene_synonym="Mds024"
                     /inference="alignment:Splign:2.1.0"
     exon            964..1036
                     /gene="Trmt11"
                     /gene_synonym="Mds024"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1168
                     /gene="Trmt11"
                     /gene_synonym="Mds024"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1289
                     /gene="Trmt11"
                     /gene_synonym="Mds024"
                     /inference="alignment:Splign:2.1.0"
     exon            1290..1563
                     /gene="Trmt11"
                     /gene_synonym="Mds024"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccggtggag gccgcgcagg cgtaccatag tagccgcaat ggcgctgccg ggctccttga
       61 atcgctatct gctgctcatg gcacaggagc acctggagtt ccgcctgccg gaaataacgt
      121 ctttactctc gctgtttgga ggccagttca ctagcagtca ggagacttat ggaaagtctc
      181 cattttggat tcttaacatt ccctctgaag atattgcaag aaacttaatg aaacgcactg
      241 tgtgtgccaa gtctttattt gaactatggg gtcatggaaa atctcccgag gagctgtatt
      301 cttctcttaa aagttacccc gtggagaaga tggttccatt tctgcattcg gactcgacat
      361 ataaaataaa gattcacaca tttaataaaa cattaactca agaagaaaaa gtggagcgga
      421 tagacgcact tgaattcctg ccattcgaag gaaaagtaaa cttaaagaaa ccacagcatg
      481 tattctccat tttggaggac tatggtttgg acccaaactg tatccccgag aatccacaca
      541 atatttattt tggcagatgg attgcagatg gacaaagaga gttaattgag tcctacagtg
      601 tcaaaaagag acattttatt ggaaatacaa gtatggatgc tggtttatcg ttcatcatgg
      661 ccaaccatgc aaaagtgaaa gaaaatgatc ttgtctttga cccctttgtt ggaacaggtg
      721 gcctcctgat agcatctgct cacttcggtg catatgtatg tgggacagac atagactaca
      781 acacggttca tggcttggga aaggctagta ggaaaaacca gaagtggcgt ggaccagatg
      841 aaaacatcag ggcaaatctt cgtcagtatg gcctagagaa gttttacctt gatgtcttgg
      901 tttcagacgc atctaagcct tcctggagga agggaacata ttttgatgca atcatcacag
      961 atcctccata tggtatcagg gaatctacaa gaaggacggg ttcacagaag gaaatactga
     1021 agggaataga aaaatgtcca gaaagccacg ttcctgtctc cttgacttat cacctgagtg
     1081 acatgttttt ggacctgatc aattttgccg ctgagaccct cgtactgggt ggaagactag
     1141 tttattggct accagtctac acaccagagt acaccgagaa gatggtgcct tggcacccct
     1201 gcctgagact tgttagcaac tgcgaacaga agctttccag tcacacagca aggcgcttga
     1261 tcacgatgga aaaggtgaag gagtttgaga acccggacga gtattcacga ctgctgagtg
     1321 atcattttct gccataccaa ggacataatt ctttccgtga gaaatatttt agtggcgtga
     1381 caaaaagaat tgccacggaa gaacagtgta gccacgaagg aaagctctga cactggccat
     1441 cgggaaagga ggagtgtttt ataaagaggc ttcagatgtg gatgtgtatg atttaaaaac
     1501 ctgcgctgat ttacaatttt tatataaata atggctatta ttcaaaagtg aataatttca
     1561 aaa
//
