LOCUS       NM_001013090            1301 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Rattus norvegicus tRNA methyltransferase 10B (Trmt10b), mRNA.
ACCESSION   NM_001013090 XM_216404
VERSION     NM_001013090.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1301)
  AUTHORS   Qi,L., Wang,Q., Guan,Z., Wu,Y., Shen,C., Hong,S., Cao,J., Zhang,X.,
            Yan,C. and Yin,P.
  TITLE     Cryo-EM structure of the human mitochondrial translocase TIM22
            complex
  JOURNAL   Cell Res 31 (3), 369-372 (2021)
   PUBMED   32901109
REFERENCE   2  (bases 1 to 1301)
  AUTHORS   Vilardo,E., Nachbagauer,C., Buzet,A., Taschner,A., Holzmann,J. and
            Rossmanith,W.
  TITLE     A subcomplex of human mitochondrial RNase P is a bifunctional
            methyltransferase--extensive moonlighting in mitochondrial tRNA
            biogenesis
  JOURNAL   Nucleic Acids Res 40 (22), 11583-11593 (2012)
   PUBMED   23042678
  REMARK    Erratum:[Nucleic Acids Res. 2018 Nov 16;46(20):11126-11127. doi:
            10.1093/nar/gky931.. PMID: 30295808]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC086603.1.
            
            On Aug 31, 2012 this sequence version replaced NM_001013090.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086603.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132267
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1301              BC086603.1         5-1305
FEATURES             Location/Qualifiers
     source          1..1301
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q22"
     gene            1..1301
                     /gene="Trmt10b"
                     /gene_synonym="Rg9mtd3"
                     /note="tRNA methyltransferase 10B"
                     /db_xref="GeneID:298081"
                     /db_xref="RGD:1310735"
     exon            1..214
                     /gene="Trmt10b"
                     /gene_synonym="Rg9mtd3"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..985
                     /gene="Trmt10b"
                     /gene_synonym="Rg9mtd3"
                     /EC_number="2.1.1.221"
                     /note="RNA (guanine-9-)-methyltransferase
                     domain-containing protein 3; RNA (guanine-9-)
                     methyltransferase domain containing 3; tRNA
                     (guanine(9)-N(1))-methyltransferase TRMT10B"
                     /codon_start=1
                     /product="tRNA methyltransferase 10 homolog B"
                     /protein_id="NP_001013108.1"
                     /db_xref="GeneID:298081"
                     /db_xref="RGD:1310735"
                     /translation="MDCEWEGRPQRAGSRASQDPEGLPEARDDGLSESFLLLQMDVEY
                     DPQEKRRPANSAAWSSKNVQRKQRHWERIVSSKKSKRKQERERRKIKRAEDLGNGTCP
                     QHSKRFLKALTKEKLLEAKHSGPRLCVDLSMTQHMSKKELSRLAGQIRRLYGSNKKAS
                     RPFWIYLTGFSTDSPLYEECLRMNDGFSAYVLDVTEEDCFSLFPLETLVYLTPDSEHP
                     LEDIDLSTVYIIGGLVDESIQKKVTFQKAQEYSVKTARLPIQEHMIRCQNEKNFHSEI
                     LAINQVFDILSAYLETRDWPEALKKGVSPGKGYILQNSVE"
     exon            215..329
                     /gene="Trmt10b"
                     /gene_synonym="Rg9mtd3"
                     /inference="alignment:Splign:2.1.0"
     exon            330..454
                     /gene="Trmt10b"
                     /gene_synonym="Rg9mtd3"
                     /inference="alignment:Splign:2.1.0"
     exon            455..607
                     /gene="Trmt10b"
                     /gene_synonym="Rg9mtd3"
                     /inference="alignment:Splign:2.1.0"
     exon            608..686
                     /gene="Trmt10b"
                     /gene_synonym="Rg9mtd3"
                     /inference="alignment:Splign:2.1.0"
     exon            687..754
                     /gene="Trmt10b"
                     /gene_synonym="Rg9mtd3"
                     /inference="alignment:Splign:2.1.0"
     exon            755..878
                     /gene="Trmt10b"
                     /gene_synonym="Rg9mtd3"
                     /inference="alignment:Splign:2.1.0"
     exon            879..1279
                     /gene="Trmt10b"
                     /gene_synonym="Rg9mtd3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgtcaggaat cagctgtgta agtggcacag gcgcatggac tgtgagtggg aagggaggcc
       61 tcagagagca ggctctcggg cctcgcagga cccagaaggc ctcccagagg ccagagacga
      121 cggactctct gagagcttcc tgcttctgca gatggatgtg gaatacgacc cccaagaaaa
      181 gcgccgccct gcgaacagcg ccgcgtggag ctcgaaaaat gtgcaaagaa agcagagaca
      241 ctgggaaagg atagtctcct caaagaagag caaacggaag caggaaagag agcgaaggaa
      301 aatcaagcgt gcagaagacc tgggtaacgg cacctgccca cagcacagca aacgtttttt
      361 gaaagcctta accaaagaga aacttttgga agccaaacac tcaggaccaa gactgtgtgt
      421 tgacttgagc atgacccagc acatgtccaa gaaggaactg agtaggttgg ccggacagat
      481 ccgaaggctg tatggttcaa acaaaaaagc cagcaggccc ttttggattt accttactgg
      541 attctcaact gacagccccc tctatgagga atgcctgagg atgaatgatg gattttctgc
      601 ttacgtgctc gacgtgacag aagaagactg ctttagcctg tttcccctgg aaacccttgt
      661 gtacctgact cctgactctg aacaccccct tgaagacatt gatctgagca cagtttacat
      721 tattggtgga cttgtagatg agagcattca gaagaaggtg acatttcaaa aagcccaaga
      781 atactctgtc aagacagccc ggttgccaat ccaggaacac atgatcaggt gccagaatga
      841 gaaaaacttc cattccgaaa tcctggccat caaccaagtg ttcgatatcc tgtctgctta
      901 cttggaaact cgtgactggc ctgaagcatt gaagaaagga gtttctccag gaaaaggcta
      961 cattcttcag aattcagtgg aatgatgggc agcctgagat tccggctaca gggggtgagg
     1021 tgctggggtg ccttgatcaa aggatgcagc aaaaggtggc agtggcacac acttgcctcc
     1081 acatgctgtc ttggatcttt gaaagccatc agaggcaagg accacatttt acactgtgtt
     1141 ttactcactg gaagtgtcct gataaaacat ggttaaaaaa atgtttatgt taaggaatca
     1201 ctaaaatatg tcattctggg tgttaactca tgctttgtac atcctgttta taaaaggtct
     1261 acttttagag atgtttaaaa aaaaaaaaaa aaaaaaaaaa a
//
