LOCUS       NM_001134981            2816 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus thyroid hormone receptor interactor 4 (Trip4),
            mRNA.
ACCESSION   NM_001134981
VERSION     NM_001134981.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2816)
  AUTHORS   Davignon,L., Chauveau,C., Julien,C., Dill,C., Duband-Goulet,I.,
            Cabet,E., Buendia,B., Lilienbaum,A., Rendu,J., Minot,M.C.,
            Guichet,A., Allamand,V., Vadrot,N., Faure,J., Odent,S., Lazaro,L.,
            Leroy,J.P., Marcorelles,P., Dubourg,O. and Ferreiro,A.
  TITLE     The transcription coactivator ASC-1 is a regulator of skeletal
            myogenesis, and its deficiency causes a novel form of congenital
            muscle disease
  JOURNAL   Hum Mol Genet 25 (8), 1559-1573 (2016)
   PUBMED   27008887
REFERENCE   2  (bases 1 to 2816)
  AUTHORS   Knierim,E., Hirata,H., Wolf,N.I., Morales-Gonzalez,S.,
            Schottmann,G., Tanaka,Y., Rudnik-Schoneborn,S., Orgeur,M.,
            Zerres,K., Vogt,S., van Riesen,A., Gill,E., Seifert,F., Zwirner,A.,
            Kirschner,J., Goebel,H.H., Hubner,C., Stricker,S., Meierhofer,D.,
            Stenzel,W. and Schuelke,M.
  TITLE     Mutations in Subunits of the Activating Signal Cointegrator 1
            Complex Are Associated with Prenatal Spinal Muscular Atrophy and
            Congenital Bone Fractures
  JOURNAL   Am J Hum Genet 98 (3), 473-489 (2016)
   PUBMED   26924529
REFERENCE   3  (bases 1 to 2816)
  AUTHORS   Yoo,H.M., Kang,S.H., Kim,J.Y., Lee,J.E., Seong,M.W., Lee,S.W.,
            Ka,S.H., Sou,Y.S., Komatsu,M., Tanaka,K., Lee,S.T., Noh,D.Y.,
            Baek,S.H., Jeon,Y.J. and Chung,C.H.
  TITLE     Modification of ASC1 by UFM1 is crucial for ERalpha transactivation
            and breast cancer development
  JOURNAL   Mol Cell 56 (2), 261-274 (2014)
   PUBMED   25219498
REFERENCE   4  (bases 1 to 2816)
  AUTHORS   Slater,L.H., Hett,E.C., Clatworthy,A.E., Mark,K.G. and Hung,D.T.
  TITLE     CCT chaperonin complex is required for efficient delivery of
            anthrax toxin into the cytosol of host cells
  JOURNAL   Proc Natl Acad Sci U S A 110 (24), 9932-9937 (2013)
   PUBMED   23716698
REFERENCE   5  (bases 1 to 2816)
  AUTHORS   Vaz Meirelles,G., Ferreira Lanza,D.C., da Silva,J.C., Santana
            Bernachi,J., Paes Leme,A.F. and Kobarg,J.
  TITLE     Characterization of hNek6 interactome reveals an important role for
            its short N-terminal domain and colocalization with proteins at the
            centrosome
  JOURNAL   J Proteome Res 9 (12), 6298-6316 (2010)
   PUBMED   20873783
REFERENCE   6  (bases 1 to 2816)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
REFERENCE   7  (bases 1 to 2816)
  AUTHORS   Jung,D.J., Sung,H.S., Goo,Y.W., Lee,H.M., Park,O.K., Jung,S.Y.,
            Lim,J., Kim,H.J., Lee,S.K., Kim,T.S., Lee,J.W. and Lee,Y.C.
  TITLE     Novel transcription coactivator complex containing activating
            signal cointegrator 1
  JOURNAL   Mol Cell Biol 22 (14), 5203-5211 (2002)
   PUBMED   12077347
REFERENCE   8  (bases 1 to 2816)
  AUTHORS   Kim,H.J., Yi,J.Y., Sung,H.S., Moore,D.D., Jhun,B.H., Lee,Y.C. and
            Lee,J.W.
  TITLE     Activating signal cointegrator 1, a novel transcription coactivator
            of nuclear receptors, and its cytosolic localization under
            conditions of serum deprivation
  JOURNAL   Mol Cell Biol 19 (9), 6323-6332 (1999)
   PUBMED   10454579
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473975.1.
            
            [WARNING] On Oct 7, 2024 this sequence was replaced by
            NM_001134981.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMD00132261, SAMD00132262
                              [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2816
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..2816
                     /gene="Trip4"
                     /note="thyroid hormone receptor interactor 4"
                     /db_xref="GeneID:315769"
                     /db_xref="RGD:1306838"
     exon            1..246
                     /gene="Trip4"
                     /inference="alignment:Splign:2.1.0"
     exon            247..396
                     /gene="Trip4"
                     /inference="alignment:Splign:2.1.0"
     exon            397..627
                     /gene="Trip4"
                     /inference="alignment:Splign:2.1.0"
     exon            628..936
                     /gene="Trip4"
                     /inference="alignment:Splign:2.1.0"
     CDS             836..2581
                     /gene="Trip4"
                     /codon_start=1
                     /product="activating signal cointegrator 1"
                     /protein_id="NP_001128453.1"
                     /db_xref="GeneID:315769"
                     /db_xref="RGD:1306838"
                     /translation="MAVAGAASGEPLVHWCTQQLRKTFALDVSEEIIQYVLSIESAEE
                     IRDYVTDLLQGNEGKKGQFIEDLITKWQKKDQECISDSFQQCWKKDESLDGQRSVDQL
                     KRSRRKGRNKQEVPAFPEPDVTVEVKTPLDLAKAQEGNSSVKKKTRFVSLYTREGQDK
                     LAVLLPGRHPCDCLGQKHKLINNCLVCGRIVCEQEGSGPCLFCGSLVCTNEEQDILQR
                     DSNKSQKLLKKLMSGAENSGKVDISTKDHPPHQESRMKSGLEKAVKHKEKLLEFDRTS
                     IRRTQVIDDESDYFASDSNQWLSKVERDMLQKREEELRELRHASRLSKKVTIDFAGRK
                     ILEDENPLAEYHSRLDETIQAIANGTLNQSLVTSDRSSEEPLGVLVNPNMYQAPPQWV
                     DNTGSAPPKKTSLSVGPRLELSLHPHQLRIQDQEFQEGFDGGWCLSVHQPWASLLVKG
                     IKRVEGRSWYTPHRGRLWIAATGKRPSTQEVSELQATYRLLRGKDVEFPNDYPSGCLL
                     GCVDLIDCLSQKQFQEQFPDISQESDSPFVFICKNPQEMVVKFPIKGNPKIWKLDSKI
                     HQGAKKGLMKQNKAV"
     exon            937..1106
                     /gene="Trip4"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..1240
                     /gene="Trip4"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..1453
                     /gene="Trip4"
                     /inference="alignment:Splign:2.1.0"
     exon            1454..1532
                     /gene="Trip4"
                     /inference="alignment:Splign:2.1.0"
     exon            1533..1662
                     /gene="Trip4"
                     /inference="alignment:Splign:2.1.0"
     exon            1663..1878
                     /gene="Trip4"
                     /inference="alignment:Splign:2.1.0"
     exon            1879..2005
                     /gene="Trip4"
                     /inference="alignment:Splign:2.1.0"
     exon            2006..2193
                     /gene="Trip4"
                     /inference="alignment:Splign:2.1.0"
     exon            2194..2318
                     /gene="Trip4"
                     /inference="alignment:Splign:2.1.0"
     exon            2319..2410
                     /gene="Trip4"
                     /inference="alignment:Splign:2.1.0"
     exon            2411..2513
                     /gene="Trip4"
                     /inference="alignment:Splign:2.1.0"
     exon            2514..2816
                     /gene="Trip4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggctcaatgt agctgcttct ttcagctaat ctccgacacc agctccaaat tacacacacc
       61 tcgccccttc tgggatccta ggccagctcg gcggctcctc ccaaagctcc tctctccggc
      121 ctcttgcggc agtttctttc tcactgtcta gctagcatct ccctctggtg gatttcctgt
      181 cgtttcaacc aggcttttgc atgcagttcg ttctgaaccg gctccagaag tcgaatagtg
      241 aagtgggaaa ctgaacccag ggacatacgc tagataggca ctccactaca gagctacaaa
      301 catatctcta gttgtggctt tttgagactg tctcaccatg cattccaggc tggcttcaac
      361 tcctggatct gtctcaatcc ttgtaattaa aggcattgaa actccaggag gcttaagatt
      421 agtattctcc atctaattaa accttgagat gatcttcaag gcagtccagt ttaagcttct
      481 caagatttcc tgagttataa ccagtgggct gagtagatgc gaagatctgg ttttgttttc
      541 cttgcaacgc tggatggcca gatgccattt agtccaattt caaaatgtgg tctggcctga
      601 gtctcttaat ggataaggca cagaaagctg gagttgcccc tcagtaccaa agaacagtca
      661 agcacttttc ttccccatac gtgtaaaaca gacccggaag ctgggagaag ccgcgcaacg
      721 gagcagggcg gtgcgaactt acggaaccct agtcaacgag gtcggcgttg caaagggaac
      781 tagtccagcg caggacgaga agcttttgca gcccagctgg ttccggtcgg ggaagatggc
      841 ggtagctggg gcggcatccg gagagccact agtacactgg tgcacacagc aattgcgaaa
      901 aactttcgcc ttggatgtca gcgaggagat catacaatat gttttgtcaa ttgagagtgc
      961 cgaagaaata cgagactatg tgacagatct tctccaggga aatgagggta aaaagggtca
     1021 attcatagaa gatcttataa ccaaatggca aaagaaggat caggagtgca tttctgattc
     1081 ttttcaacag tgctggaaaa aagatgaaag tttagatgga cagagatcag tggaccagct
     1141 aaagcggagt aggaggaaag gaagaaacaa acaggaagtt cctgcatttc ctgaacctga
     1201 cgtgactgtg gaggtcaaaa cacctttaga tttggccaag gcacaagaag gcaacagctc
     1261 cgtaaagaag aagacgagat ttgtcagctt atatacacga gaggggcagg acaaacttgc
     1321 agtcctcctt cctggtcgtc acccgtgtga ttgcttgggc cagaagcaca aactcatcaa
     1381 taactgtctg gtctgtgggc ggattgtctg tgaacaggag ggttcaggcc cctgcttgtt
     1441 ctgtggctct ttggtgtgta ccaatgaaga acaggacatt ttacaacgtg actcaaacaa
     1501 aagccagaaa ctgctgaaga agctcatgtc aggggcagag aattctggaa aggtggatat
     1561 ctctaccaag gaccatcctc ctcatcagga atctcgaatg aagtctggtt tggagaaggc
     1621 tgtcaagcac aaggaaaaac tgttagagtt cgataggact agtatccgaa ggacccaagt
     1681 cattgatgat gaatcagatt actttgccag tgattctaat cagtggctgt ccaaagttga
     1741 gcgagacatg ctacagaaac gagaggaaga gctgagagaa ctccgacatg cctctcgact
     1801 ttctaagaaa gtcaccattg actttgcggg gcggaagatc ctagaagatg aaaacccact
     1861 ggcagagtat cacagcagac tagatgagac aatacaagcc attgccaatg gaactttgaa
     1921 ccagtcactg gtcacgtctg atagatcttc tgaagagcct ttgggagttc tggtaaaccc
     1981 taacatgtac caggcccctc ctcagtgggt ggacaacact gggtcagcac caccaaagaa
     2041 aacttcactc tcagtaggac caagactaga gctcagttta catcctcacc agcttcgaat
     2101 ccaggaccag gaattccagg aaggctttga tggtggctgg tgcctgtctg tgcatcagcc
     2161 ctgggcttct ctgcttgtca aggggattaa aagggtggag ggcagatcct ggtatactcc
     2221 tcacagagga agactttgga tagcagccac aggcaaaaga ccttcgactc aagaagtctc
     2281 agaactccag gctacctacc gtcttcttcg cgggaaagat gtagaatttc caaatgacta
     2341 tccatcaggt tgtcttctgg gctgtgtgga ccttattgat tgcttatccc agaaacaatt
     2401 ccaggagcag ttcccggaca tcagtcaaga gtctgactct ccatttgtct tcatctgcaa
     2461 aaatccccag gaaatggttg tgaagttccc tattaaagga aatcctaaaa tctggaaact
     2521 ggattccaag atccatcaag gagcaaagaa ggggttaatg aagcagaata aagctgtctg
     2581 acccaggaaa aaaggaacta tacaacatag tggagtcttg tgtactaaat tgctatccgc
     2641 tggtcctttg ggatggaagc agtagaaagc taaaaggctt ggcaccaggc ttcggtctct
     2701 gagaatttaa actcttacca aatctgtata tttttttctt aaaggatggg attctttatg
     2761 tagtgggtca aaaatcttta aatatgttat ttataaaaac tcattttaaa aattct
//
