LOCUS       NM_001011930            1821 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus thyroid hormone receptor interactor 13 (Trip13),
            mRNA.
ACCESSION   NM_001011930 XM_217741
VERSION     NM_001011930.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1821)
  AUTHORS   Yost,S., de Wolf,B., Hanks,S., Zachariou,A., Marcozzi,C.,
            Clarke,M., de Voer,R., Etemad,B., Uijttewaal,E., Ramsay,E.,
            Wylie,H., Elliott,A., Picton,S., Smith,A., Smithson,S., Seal,S.,
            Ruark,E., Houge,G., Pines,J., Kops,G.J.P.L. and Rahman,N.
  TITLE     Biallelic TRIP13 mutations predispose to Wilms tumor and chromosome
            missegregation
  JOURNAL   Nat Genet 49 (7), 1148-1151 (2017)
   PUBMED   28553959
REFERENCE   2  (bases 1 to 1821)
  AUTHORS   Roig,I., Dowdle,J.A., Toth,A., de Rooij,D.G., Jasin,M. and
            Keeney,S.
  TITLE     Mouse TRIP13/PCH2 is required for recombination and normal
            higher-order chromosome structure during meiosis
  JOURNAL   PLoS Genet 6 (8), e1001062 (2010)
   PUBMED   20711356
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1821)
  AUTHORS   Li,X.C. and Schimenti,J.C.
  TITLE     Mouse pachytene checkpoint 2 (trip13) is required for completing
            meiotic recombination but not synapsis
  JOURNAL   PLoS Genet 3 (8), e130 (2007)
   PUBMED   17696610
  REMARK    Erratum:[PLoS Genet. 2007 Sep 7;3(9):e168. Li, Xin [corrected to
            Li, Xin Chenglin]]
REFERENCE   4  (bases 1 to 1821)
  AUTHORS   Stelzl,U., Worm,U., Lalowski,M., Haenig,C., Brembeck,F.H.,
            Goehler,H., Stroedicke,M., Zenkner,M., Schoenherr,A., Koeppen,S.,
            Timm,J., Mintzlaff,S., Abraham,C., Bock,N., Kietzmann,S.,
            Goedde,A., Toksoz,E., Droege,A., Krobitsch,S., Korn,B.,
            Birchmeier,W., Lehrach,H. and Wanker,E.E.
  TITLE     A human protein-protein interaction network: a resource for
            annotating the proteome
  JOURNAL   Cell 122 (6), 957-968 (2005)
   PUBMED   16169070
REFERENCE   5  (bases 1 to 1821)
  AUTHORS   Suzuki,H., Fukunishi,Y., Kagawa,I., Saito,R., Oda,H., Endo,T.,
            Kondo,S., Bono,H., Okazaki,Y. and Hayashizaki,Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083900.1.
            
            On Feb 11, 2005 this sequence version replaced XM_217741.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083900.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132291, SAMD00132296
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1821
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1p11"
     gene            1..1821
                     /gene="Trip13"
                     /note="thyroid hormone receptor interactor 13"
                     /db_xref="GeneID:292206"
                     /db_xref="RGD:1308516"
     exon            1..203
                     /gene="Trip13"
                     /inference="alignment:Splign:2.1.0"
     CDS             112..1410
                     /gene="Trip13"
                     /note="thyroid receptor-interacting protein 13; TRIP-13;
                     TR-interacting protein 13"
                     /codon_start=1
                     /product="pachytene checkpoint protein 2 homolog"
                     /protein_id="NP_001011930.1"
                     /db_xref="GeneID:292206"
                     /db_xref="RGD:1308516"
                     /translation="MDDAVGDLKQALPCVAESPAVHVEVLQRSGSTAKKEDIKQSVYR
                     LLKRHNIVFGDYVWTEFDEPFLTRNVQSVSIVDTELKAKDPQPIDLSACTIALHIFQL
                     NEEGPSSENLDEETENIIAASHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFS
                     DKNVDSNLITWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLF
                     SKWFSESGKLVTKMFQKIQDLIDDKEALVFVLIDEVESLTAARNACRAGAEPSDAIRV
                     VNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSC
                     LEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLSEISRKSEGLSGRVLRKLP
                     FLAHALYIQAPSVTIEGFLQALSLAVDKQFEEKKKLSAHV"
     exon            204..369
                     /gene="Trip13"
                     /inference="alignment:Splign:2.1.0"
     exon            370..499
                     /gene="Trip13"
                     /inference="alignment:Splign:2.1.0"
     exon            500..555
                     /gene="Trip13"
                     /inference="alignment:Splign:2.1.0"
     exon            556..646
                     /gene="Trip13"
                     /inference="alignment:Splign:2.1.0"
     exon            647..719
                     /gene="Trip13"
                     /inference="alignment:Splign:2.1.0"
     exon            720..783
                     /gene="Trip13"
                     /inference="alignment:Splign:2.1.0"
     exon            784..870
                     /gene="Trip13"
                     /inference="alignment:Splign:2.1.0"
     exon            871..977
                     /gene="Trip13"
                     /inference="alignment:Splign:2.1.0"
     exon            978..1131
                     /gene="Trip13"
                     /inference="alignment:Splign:2.1.0"
     exon            1132..1244
                     /gene="Trip13"
                     /inference="alignment:Splign:2.1.0"
     exon            1245..1314
                     /gene="Trip13"
                     /inference="alignment:Splign:2.1.0"
     exon            1315..1446
                     /gene="Trip13"
                     /inference="alignment:Splign:2.1.0"
     exon            1447..1798
                     /gene="Trip13"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggccagggt ggatcttcgt acagctgaga agactgtccc acagggcgcc gagaggcgac
       61 cgcgacctca ttctggctgg ccgcatttcc tcggctcccg gctgcggcgc catggacgac
      121 gcggtgggcg acctgaagca agcgcttccg tgtgttgccg agtcgcccgc ggtccatgtg
      181 gaggttttgc agcgcagcgg aagcactgca aaaaaagaag atataaagca gagcgtttac
      241 aggctgctca agaggcataa cattgtgttt ggagattacg tgtggactga gtttgatgag
      301 ccttttctaa ctagaaatgt tcagtcggta tctattgttg acacagaatt aaaggctaaa
      361 gaccctcagc ccattgatct gagtgcatgc accattgcac ttcacatctt ccagctgaat
      421 gaagaaggcc ccagcagtga aaatttggat gaagaaacag aaaatataat tgcagcaagt
      481 cactgggttt tgcctgcagc tgaatttcat gggctttggg atagcctcgt gtatgatgtg
      541 gaggtcaaat cacatctcct tgactatgtg atgaccacct tactattctc agacaagaat
      601 gtggacagca accttatcac ctggaaccgg gtggtactgc tgcacggtcc tccgggtact
      661 ggaaagacat ccctttgtaa ggcattagcc cagaaactga ccatcagact gtcaagcagg
      721 taccggtatg gccagttaat tgaaataaac agccacagcc tattttctaa gtggttttca
      781 gaaagtggca agttggtaac taagatgttc cagaagattc aggacttgat tgatgataaa
      841 gaagctttgg tgtttgttct gattgatgag gtggagagtc ttacagctgc tcgaaatgct
      901 tgcagggcag gcgcagagcc atcagatgct atccgtgtag tcaatgctgt gttgactcag
      961 attgatcaga ttaaaaggca ttccaatgtg gtgattctga ccacttccaa catcactgag
     1021 aagattgatg tggcctttgt ggatagagct gacatcaaac aatatattgg ccccccctct
     1081 gcagcagcca tcttcaaaat ctacctgtct tgtttagaag aactgatgaa gtgccagatc
     1141 atatatcccc gtcagcagct gttgaccctt cgagagctgg aaatgattgg cttcattgaa
     1201 aataatgtgt cgaagttgag cctccttttg agtgaaattt caaggaagag tgagggcctc
     1261 agcggccggg tcttgaggaa acttcctttc ctggctcatg cgctgtatat ccaggctccc
     1321 agcgtcacca tcgagggttt cctccaggcc ctgtcactgg cagtggacaa acagtttgag
     1381 gagaaaaaga aactctcagc tcatgtttga tcccagacat ccatatctgt ggttttcaat
     1441 ggacaggccc tgccaaggga ttgccacttg tgcaaatacc ccgggagaaa ggggattcct
     1501 gtgccaatgt cctcctacgt acagaggaat gaatgcaact gctgctaatt cctatggagg
     1561 gaacacctgc tacagagagc cagagtgccc tgtctctatc tgccctgctg gatattctgg
     1621 aaggttctgt aagtcggatc acactgagtg tgcttccaac ccctaccaca atggggtgct
     1681 gtgccaggat ggcgtcaata actgcacctg cttctgtatg cctgggtacc aaggcaggtg
     1741 ttgtgacttg aaaattgagt ttaagtcttt aaccaaatct ttcagtgggt acacacaaaa
     1801 aaaaaaaaaa aaaaaaaaaa a
//
